Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NIPS1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in NIPS1_HUMAN
GO:0003723 RNA binding 34.1463 4 no
GO:0046872 metal ion binding 26.8293 4 no
GO:0017076 purine nucleotide binding 25.6098 4 no
GO:0032555 purine ribonucleotide binding 25.6098 4 no
GO:0035639 purine ribonucleoside triphosphate binding 24.3902 4 no
GO:0030554 adenyl nucleotide binding 21.9512 5 no
GO:0032559 adenyl ribonucleotide binding 21.9512 5 no
GO:0005524 ATP binding 20.7317 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in NIPS1_HUMAN
GO:0031323 regulation of cellular metabolic process 48.7805 4 no
GO:0048522 positive regulation of cellular process 48.7805 4 no
GO:0051171 regulation of nitrogen compound metabolic process 47.5610 4 no
GO:0080090 regulation of primary metabolic process 47.5610 4 no
GO:0060255 regulation of macromolecule metabolic process 46.3415 4 no
GO:0009893 positive regulation of metabolic process 39.0244 4 no
GO:0022607 cellular component assembly 36.5854 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 36.5854 5 no
GO:0010604 positive regulation of macromolecule metabolic process 35.3659 5 no
GO:0031325 positive regulation of cellular metabolic process 35.3659 5 no
GO:0048523 negative regulation of cellular process 35.3659 4 no
GO:0051128 regulation of cellular component organization 35.3659 4 no
GO:0006996 organelle organization 34.1463 4 no
GO:0051246 regulation of protein metabolic process 32.9268 5 no
GO:0009889 regulation of biosynthetic process 31.7073 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.7073 5 no
GO:0031326 regulation of cellular biosynthetic process 31.7073 5 no
GO:0008104 protein localization 30.4878 4 no
GO:0010556 regulation of macromolecule biosynthetic process 29.2683 5 no
GO:0010941 regulation of cell death 29.2683 4 no
GO:0043933 protein-containing complex organization 28.0488 4 no
GO:0042981 regulation of apoptotic process 28.0488 6 no
GO:0043067 regulation of programmed cell death 28.0488 5 no
GO:0010646 regulation of cell communication 26.8293 4 no
GO:0009966 regulation of signal transduction 25.6098 4 no
GO:0009891 positive regulation of biosynthetic process 24.3902 5 no
GO:0031328 positive regulation of cellular biosynthetic process 24.3902 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 24.3902 6 no
GO:0065003 protein-containing complex assembly 24.3902 5 no
GO:0019220 regulation of phosphate metabolic process 23.1707 6 no
GO:0051174 regulation of phosphorus metabolic process 23.1707 5 no
GO:0032880 regulation of protein localization 23.1707 5 no
GO:0060341 regulation of cellular localization 23.1707 4 no
GO:0009892 negative regulation of metabolic process 21.9512 4 no
GO:0043085 positive regulation of catalytic activity 21.9512 4 no
GO:1902531 regulation of intracellular signal transduction 21.9512 5 no
GO:0051130 positive regulation of cellular component organization 21.9512 5 no
GO:0071702 organic substance transport 21.9512 4 no
GO:0071705 nitrogen compound transport 21.9512 4 no
GO:0007005 mitochondrion organization 20.7317 5 no
GO:0031324 negative regulation of cellular metabolic process 20.7317 5 no
GO:0051049 regulation of transport 20.7317 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 20.7317 5 no
GO:0051247 positive regulation of protein metabolic process 20.7317 6 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.7317 6 no
GO:0033043 regulation of organelle organization 20.7317 5 no
GO:0010468 regulation of gene expression 20.7317 5 no
GO:0007600 sensory perception 2.4390 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in NIPS1_HUMAN
DOID:0050700 cardiomyopathy 3.6585 4 no
DOID:0060036 intrinsic cardiomyopathy 3.6585 5 no
DOID:114 heart disease 3.6585 3 no
DOID:2843 long QT syndrome 3.6585 6 no
DOID:10273 heart conduction disease 2.4390 4 no
DOID:1289 neurodegenerative disease 2.4390 4 no
DOID:331 central nervous system disease 2.4390 3 no
DOID:700 mitochondrial metabolism disease 2.4390 3 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
COX7C_HUMAN [view interactions] High throughput no yes
ADAS_HUMAN [view interactions] High throughput no yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
ATPA_HUMAN [view interactions] High throughput no yes
ATPO_HUMAN [view interactions] High throughput no yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
SC61B_HUMAN [view interactions] High throughput no yes
NB5R3_HUMAN [view interactions] High throughput no yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5H_HUMAN [view interactions] High throughput no yes
SCPDL_HUMAN [view entry] [view interactions] High throughput yes yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
RCN2_HUMAN [view interactions] High throughput no yes
AN34C_HUMAN [view interactions] High throughput no no
ATPG_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
ODBA_HUMAN [view interactions] High throughput no yes
CALR_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
COX7R_HUMAN [view entry] [view interactions] High throughput yes no
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
COX2_HUMAN [view entry] [view interactions] High throughput yes yes
ML12A_HUMAN [view interactions] High throughput no no
NDUA9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
NDUS8_HUMAN [view interactions] High throughput no yes
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
RCAF1_HUMAN [view interactions] High throughput no yes
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
TOM22_HUMAN [view interactions] High throughput no yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
TOM40_HUMAN [view interactions] High throughput no yes
TOM5_HUMAN [view interactions] High throughput no yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR8_HUMAN [view interactions] High throughput no yes
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
BLMH_HUMAN [view interactions] High throughput no yes
RUFY3_HUMAN [view entry] [view interactions] High throughput yes yes
GRSF1_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no yes
MRES1_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
FIS1_HUMAN [view entry] [view interactions] High throughput yes yes
EFGM_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
MARH5_HUMAN [view interactions] High throughput no no
MCUB_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
MET17_HUMAN [view interactions] High throughput no yes
MFN2_HUMAN [view entry] [view interactions] High throughput yes yes
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
IF2M_HUMAN [view interactions] High throughput no yes
IF3M_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
RF1ML_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
OCAD1_HUMAN [view interactions] High throughput no yes
MPPA_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
RUSD4_HUMAN [view interactions] High throughput no yes
S2546_HUMAN [view entry] [view interactions] High throughput yes yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
SURF1_HUMAN [view interactions] High throughput no yes
TACO1_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
TEFM_HUMAN [view interactions] High throughput no no
TMM70_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
VWA8_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
SYAM_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
ACBP_HUMAN [view interactions] High throughput no yes
RGS2_HUMAN [view interactions] High throughput no no
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
GBRAP_HUMAN [view interactions] High throughput no no
GBRL1_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
NIPS2_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
KNTC1_HUMAN [view interactions] High throughput no no
RT18A_HUMAN [view interactions] High throughput no yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
FAT1_HUMAN [view interactions] High throughput no yes
AAPK2_HUMAN [view interactions] High throughput no yes
NS1BP_HUMAN [view interactions] High throughput no yes
TNC18_HUMAN [view interactions] High throughput no yes
GANAB_HUMAN [view interactions] High throughput no yes
BCL7B_HUMAN [view interactions] High throughput no yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
ZN281_HUMAN [view interactions] High throughput no no
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
NSE2_HUMAN [view interactions] High throughput no yes
ASCC2_HUMAN [view interactions] High throughput no yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
HP1B3_HUMAN [view interactions] High throughput no yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
DJC21_HUMAN [view interactions] High throughput no yes
POP1_HUMAN [view interactions] High throughput no no
TF3C5_HUMAN [view interactions] High throughput no yes
LCOR_HUMAN [view interactions] High throughput no yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
NMES1_HUMAN [view interactions] High throughput no no
COQ9_HUMAN [view interactions] High throughput no yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
CHCH2_HUMAN [view interactions] High throughput no yes
CISD3_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
MOT11_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
FXRD2_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
CXCR2_HUMAN [view interactions] High throughput no no
TBC17_HUMAN [view entry] [view interactions] High throughput yes yes
IF140_HUMAN [view interactions] High throughput no yes
WDR19_HUMAN [view interactions] High throughput no yes
CT2NL_HUMAN [view interactions] High throughput no yes
AMOT_HUMAN [view interactions] High throughput no no
TECT3_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
ICT1_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
UBE2B_HUMAN [view interactions] High throughput no no
KCMF1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
TCF20_HUMAN [view interactions] High throughput no yes
HPSE_HUMAN [view interactions] High throughput no no
FND3A_HUMAN [view interactions] High throughput no yes
ARHGC_HUMAN [view interactions] High throughput no yes
HAUS6_HUMAN [view interactions] High throughput no yes
PTPM1_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
ARI1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
AMRA1_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
RHG17_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
ATX2_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
NBR1_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
IL25_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
SAM50_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOH_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
COA3_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
SCMC1_HUMAN [view interactions] High throughput no no
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
TRPV6_HUMAN [view interactions] Computational no no