COX7R_HUMAN
Evidence for PS localization
Functions
Involved in the regulation of oxidative phosphorylation and energy metabolism . Necessary for the assembly of mitochondrial respiratory supercomplex . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in COX7R_HUMAN |
|---|---|---|---|---|
| GO:0015399 | primary active transmembrane transporter activity | 38.0952 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 38.0952 | 5 | yes |
| GO:0046872 | metal ion binding | 35.7143 | 4 | no |
| GO:0008324 | cation transmembrane transporter activity | 26.1905 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 26.1905 | 4 | yes |
| GO:0015078 | proton transmembrane transporter activity | 23.8095 | 5 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 23.8095 | 4 | yes |
| GO:0004129 | cytochrome-c oxidase activity | 14.2857 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in COX7R_HUMAN |
|---|---|---|---|---|
| GO:0009060 | aerobic respiration | 47.6190 | 6 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 47.6190 | 4 | yes |
| GO:0045333 | cellular respiration | 47.6190 | 5 | yes |
| GO:0022900 | electron transport chain | 45.2381 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 45.2381 | 5 | yes |
| GO:0019646 | aerobic electron transport chain | 42.8571 | 6 | yes |
| GO:0022607 | cellular component assembly | 28.5714 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 28.5714 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 26.1905 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 23.8095 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 23.8095 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 23.8095 | 4 | no |
| GO:0006996 | organelle organization | 21.4286 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 21.4286 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 21.4286 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 21.4286 | 4 | no |
| GO:0010941 | regulation of cell death | 21.4286 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 21.4286 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 21.4286 | 5 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 21.4286 | 4 | no |
| GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen | 16.6667 | 7 | yes |
| GO:0007005 | mitochondrion organization | 14.2857 | 5 | yes |
| GO:0043467 | regulation of generation of precursor metabolites and energy | 9.5238 | 5 | yes |
| GO:0002082 | regulation of oxidative phosphorylation | 4.7619 | 8 | yes |
| GO:0043457 | regulation of cellular respiration | 4.7619 | 6 | yes |
| GO:1903715 | regulation of aerobic respiration | 4.7619 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBPQ_HUMAN | [view interactions] | High throughput | no | no |
| GPR34_HUMAN | [view interactions] | High throughput | no | yes |
| NAT8B_HUMAN | [view interactions] | High throughput | no | no |
| COX5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| CX6A1_HUMAN | [view interactions] | High throughput | no | yes |
| ADCY9_HUMAN | [view interactions] | High throughput | no | yes |
| PGES2_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX42_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| CX7B2_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| ACOT9_HUMAN | [view interactions] | High throughput | no | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA3_HUMAN | [view interactions] | High throughput | no | yes |
| GBG5_HUMAN | [view interactions] | High throughput | no | no |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MGST1_HUMAN | [view interactions] | High throughput | no | no |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AN34C_HUMAN | [view interactions] | High throughput | no | no |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| RCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ML12A_HUMAN | [view interactions] | High throughput | no | no |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN782_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
| TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| COX5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGAB_HUMAN | [view interactions] | High throughput | no | no |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX3_HUMAN | [view interactions] | Computational | no | yes |
| QCR6L_HUMAN | [view interactions] | Computational | no | yes |
| RCAS1_HUMAN | [view interactions] | Computational | no | yes |
| NMDE4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CX7A1_HUMAN | [view interactions] | Computational | no | no |
| COX1_HUMAN | [view interactions] | Computational | no | yes |