COX2_HUMAN
Evidence for PS localization
Functions
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in COX2_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 32.5000 | 4 | yes |
| GO:0015399 | primary active transmembrane transporter activity | 27.5000 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 26.2500 | 5 | yes |
| GO:0008324 | cation transmembrane transporter activity | 15.0000 | 4 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 13.7500 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 13.7500 | 4 | yes |
| GO:0015078 | proton transmembrane transporter activity | 12.5000 | 5 | yes |
| GO:0004129 | cytochrome-c oxidase activity | 7.5000 | 4 | yes |
| GO:0046914 | transition metal ion binding | 6.2500 | 5 | yes |
| GO:0005507 | copper ion binding | 2.5000 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in COX2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 38.7500 | 4 | yes |
| GO:0022607 | cellular component assembly | 37.5000 | 4 | no |
| GO:0015980 | energy derivation by oxidation of organic compounds | 36.2500 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 36.2500 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 35.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 35.0000 | 4 | yes |
| GO:0045333 | cellular respiration | 33.7500 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 32.5000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 32.5000 | 4 | no |
| GO:0009060 | aerobic respiration | 32.5000 | 6 | yes |
| GO:0022900 | electron transport chain | 31.2500 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 30.0000 | 5 | yes |
| GO:0019646 | aerobic electron transport chain | 28.7500 | 6 | yes |
| GO:0006996 | organelle organization | 28.7500 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.7500 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 27.5000 | 4 | yes |
| GO:0010941 | regulation of cell death | 27.5000 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 27.5000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 26.2500 | 4 | no |
| GO:0009966 | regulation of signal transduction | 25.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 25.0000 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.7500 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 23.7500 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 23.7500 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 22.5000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 22.5000 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.2500 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 21.2500 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 21.2500 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21.2500 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.0000 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 20.0000 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 15.0000 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 15.0000 | 6 | yes |
| GO:0010942 | positive regulation of cell death | 13.7500 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 12.5000 | 6 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 12.5000 | 7 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 11.2500 | 6 | yes |
| GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen | 8.7500 | 7 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 7.5000 | 4 | yes |
| GO:0062013 | positive regulation of small molecule metabolic process | 7.5000 | 5 | yes |
| GO:0030808 | regulation of nucleotide biosynthetic process | 5.0000 | 6 | yes |
| GO:0042773 | ATP synthesis coupled electron transport | 5.0000 | 6 | yes |
| GO:1900371 | regulation of purine nucleotide biosynthetic process | 5.0000 | 7 | yes |
| GO:1900542 | regulation of purine nucleotide metabolic process | 5.0000 | 6 | yes |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 5.0000 | 5 | yes |
| GO:0006140 | regulation of nucleotide metabolic process | 5.0000 | 5 | yes |
| GO:0030810 | positive regulation of nucleotide biosynthetic process | 3.7500 | 7 | yes |
| GO:0045981 | positive regulation of nucleotide metabolic process | 3.7500 | 6 | yes |
| GO:0046903 | secretion | 3.7500 | 4 | yes |
| GO:1900373 | positive regulation of purine nucleotide biosynthetic process | 3.7500 | 8 | yes |
| GO:1900544 | positive regulation of purine nucleotide metabolic process | 3.7500 | 7 | yes |
| GO:1903426 | regulation of reactive oxygen species biosynthetic process | 3.7500 | 5 | yes |
| GO:1903578 | regulation of ATP metabolic process | 3.7500 | 7 | yes |
| GO:1903580 | positive regulation of ATP metabolic process | 3.7500 | 8 | yes |
| GO:2000379 | positive regulation of reactive oxygen species metabolic process | 3.7500 | 6 | yes |
| GO:2001169 | regulation of ATP biosynthetic process | 3.7500 | 8 | yes |
| GO:2001171 | positive regulation of ATP biosynthetic process | 3.7500 | 9 | yes |
| GO:0010310 | regulation of hydrogen peroxide metabolic process | 2.5000 | 6 | yes |
| GO:0010726 | positive regulation of hydrogen peroxide metabolic process | 2.5000 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in COX2_HUMAN |
|---|---|---|---|---|
| DOID:700 | mitochondrial metabolism disease | 3.7500 | 3 | no |
| DOID:0060286 | combined oxidative phosphorylation deficiency | 2.5000 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NLGN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX41_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX5B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX6C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | Low throughput | no | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CX7A2_HUMAN | [view interactions] | Low throughput | no | no |
| CX7A1_HUMAN | [view interactions] | Low throughput | no | no |
| YMEL1_HUMAN | [view interactions] | Low throughput | no | yes |
| COX1_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| COX20_HUMAN | [view interactions] | Low throughput | no | yes |
| COA6_HUMAN | [view interactions] | Low throughput | no | yes |
| SCO2_HUMAN | [view interactions] | Low throughput | no | no |
| COX16_HUMAN | [view interactions] | Low throughput | no | no |
| PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CX6A1_HUMAN | [view interactions] | Low throughput | no | yes |
| BAP31_HUMAN | [view interactions] | Low throughput | no | yes |
| COX7B_HUMAN | [view interactions] | Low throughput | no | yes |
| COX8A_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX3_HUMAN | [view interactions] | Low throughput | no | yes |
| B2MG_HUMAN | [view interactions] | Low throughput | no | yes |
| COA3_HUMAN | [view interactions] | Low throughput | no | yes |
| HLAB_HUMAN | [view interactions] | Low throughput | no | yes |
| NRAM2_HUMAN | [view interactions] | Low throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CMC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| NELFD_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM41B_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS23_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GORS1_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| ANTR1_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGT1_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSRD_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PREB_HUMAN | [view interactions] | High throughput | no | yes |
| ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX7R_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASPH_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| ODBA_HUMAN | [view interactions] | High throughput | no | yes |
| B2L13_HUMAN | [view interactions] | High throughput | no | no |
| RCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view interactions] | High throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ML12A_HUMAN | [view interactions] | High throughput | no | no |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMRE_HUMAN | [view interactions] | High throughput | no | yes |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN782_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
| CH082_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCU_HUMAN | [view interactions] | High throughput | no | yes |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| RIDA_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA1_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| S38A1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| USF1_HUMAN | [view interactions] | High throughput | no | yes |
| RXRB_HUMAN | [view interactions] | High throughput | no | yes |
| TFEB_HUMAN | [view interactions] | High throughput | no | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| RALB_HUMAN | [view interactions] | High throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNR2_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| PINX1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RXRA_HUMAN | [view interactions] | Computational | no | yes |
| COX42_HUMAN | [view interactions] | Computational | no | no |
| CX6B2_HUMAN | [view interactions] | Computational | no | no |
| NU2M_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NU4LM_HUMAN | [view interactions] | Computational | no | no |
| QCR6L_HUMAN | [view interactions] | Computational | no | yes |
| NU4M_HUMAN | [view interactions] | Computational | no | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| QCR10_HUMAN | [view interactions] | Computational | no | no |
| IKBA_HUMAN | [view interactions] | Computational | no | yes |
| QCR9_HUMAN | [view interactions] | Computational | no | no |
| NU1M_HUMAN | [view interactions] | Computational | no | yes |
| CYB_HUMAN | [view interactions] | Computational | no | yes |
| MPPB_HUMAN | [view interactions] | Computational | no | yes |
| NDUB8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NU3M_HUMAN | [view interactions] | Computational | no | yes |
| TNFA_HUMAN | [view interactions] | Computational | no | no |
| NU5M_HUMAN | [view interactions] | Computational | no | no |
| NDUA1_HUMAN | [view interactions] | Computational | no | yes |
| COX11_HUMAN | [view interactions] | Computational | no | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SCO1_HUMAN | [view interactions] | Computational | no | yes |
| COX17_HUMAN | [view interactions] | Computational | no | yes |
| COX10_HUMAN | [view interactions] | Computational | no | yes |
| SDHA_HUMAN | [view interactions] | Computational | no | yes |
| ATP6_HUMAN | [view interactions] | Computational | no | no |
| PPARA_HUMAN | [view interactions] | Computational | no | yes |
| ATPA_HUMAN | [view interactions] | Computational | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CX6A2_HUMAN | [view interactions] | Computational | no | no |
| NU6M_HUMAN | [view interactions] | Computational | no | no |
| SMAD4_HUMAN | [view interactions] | Computational | no | yes |
| NR0B2_HUMAN | [view interactions] | Computational | no | no |
| COT1_HUMAN | [view interactions] | Computational | no | no |
| QCR6_HUMAN | [view interactions] | Computational | no | yes |
| PERM_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PGH1_HUMAN | [view interactions] | Computational | no | yes |
| QCR7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FAT1_HUMAN | [view interactions] | Computational | no | yes |
| SP1_HUMAN | [view interactions] | Computational | no | yes |
| NOS2_HUMAN | [view interactions] | Computational | no | yes |
| ATP8_HUMAN | [view interactions] | Computational | no | no |
| TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |