Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

S2546_HUMAN

May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission. [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in S2546_HUMAN
GO:0017076 purine nucleotide binding 20.8333 4 no
GO:0032555 purine ribonucleotide binding 20.8333 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in S2546_HUMAN
GO:0006996 organelle organization 50.0000 4 yes
GO:0008104 protein localization 36.1111 4 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0048522 positive regulation of cellular process 33.3333 4 no
GO:0061024 membrane organization 30.5556 4 yes
GO:0031323 regulation of cellular metabolic process 30.5556 4 no
GO:0048523 negative regulation of cellular process 29.1667 4 no
GO:0007005 mitochondrion organization 27.7778 5 yes
GO:0060255 regulation of macromolecule metabolic process 27.7778 4 no
GO:0080090 regulation of primary metabolic process 27.7778 4 no
GO:0010646 regulation of cell communication 27.7778 4 no
GO:0051128 regulation of cellular component organization 26.3889 4 no
GO:0071705 nitrogen compound transport 26.3889 4 no
GO:0051171 regulation of nitrogen compound metabolic process 26.3889 4 no
GO:0015031 protein transport 23.6111 4 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0009966 regulation of signal transduction 22.2222 4 no
GO:0022607 cellular component assembly 20.8333 4 yes
GO:0033043 regulation of organelle organization 20.8333 5 no
GO:0032990 cell part morphogenesis 9.7222 4 yes
GO:0006839 mitochondrial transport 8.3333 4 yes
GO:0000266 mitochondrial fission 6.9444 6 yes
GO:0030030 cell projection organization 6.9444 4 yes
GO:0048285 organelle fission 6.9444 5 yes
GO:0022411 cellular component disassembly 5.5556 4 yes
GO:0031175 neuron projection development 5.5556 6 yes
GO:0034330 cell junction organization 5.5556 4 yes
GO:0048812 neuron projection morphogenesis 5.5556 7 yes
GO:0048858 cell projection morphogenesis 5.5556 5 yes
GO:0050808 synapse organization 5.5556 5 yes
GO:0120036 plasma membrane bounded cell projection organization 5.5556 5 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 5.5556 6 yes
GO:1903008 organelle disassembly 5.5556 5 yes
GO:0030182 neuron differentiation 4.1667 4 yes
GO:0000422 autophagy of mitochondrion 2.7778 4 yes
GO:0007409 axonogenesis 2.7778 8 yes
GO:0007416 synapse assembly 2.7778 6 yes
GO:0021953 central nervous system neuron differentiation 2.7778 5 yes
GO:0034329 cell junction assembly 2.7778 5 yes
GO:0042552 myelination 2.7778 4 yes
GO:0061564 axon development 2.7778 7 yes
GO:0061726 mitochondrion disassembly 2.7778 6 yes
GO:0090148 membrane fission 2.7778 5 yes
GO:0090149 mitochondrial membrane fission 2.7778 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in S2546_HUMAN
DOID:574 peripheral nervous system disease 5.5556 3 no
DOID:870 neuropathy 5.5556 4 no
DOID:331 central nervous system disease 4.1667 3 no
DOID:10595 Charcot-Marie-Tooth disease 2.7778 6 no
DOID:440 neuromuscular disease 2.7778 5 no
DOID:1891 optic nerve disease 2.7778 6 no
DOID:5656 cranial nerve disease 2.7778 5 no
DOID:5723 optic atrophy 2.7778 7 no
DOID:936 brain disease 2.7778 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MTCH2_HUMAN [view entry] [view interactions] Low throughput yes yes
MFN1_HUMAN [view interactions] Low throughput no yes
MFN2_HUMAN [view entry] [view interactions] Low throughput yes yes
MIC60_HUMAN [view entry] [view interactions] Low throughput yes yes
MIC19_HUMAN [view entry] [view interactions] Low throughput yes yes
MUL1_HUMAN [view interactions] High throughput no no
TOM40_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
SAM50_HUMAN [view entry] [view interactions] High throughput yes yes
MTX1_HUMAN [view entry] [view interactions] High throughput yes yes
TMM11_HUMAN [view interactions] High throughput no no
MTX2_HUMAN [view entry] [view interactions] High throughput yes yes
MARC2_HUMAN [view interactions] High throughput no no
MFF_HUMAN [view entry] [view interactions] High throughput yes yes
MTFR2_HUMAN [view interactions] High throughput no no
PLD6_HUMAN [view interactions] High throughput no yes
ARMC1_HUMAN [view interactions] High throughput no yes
FUND2_HUMAN [view interactions] High throughput no yes
MTFR1_HUMAN [view interactions] High throughput no yes
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
MIC25_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH1_HUMAN [view entry] [view interactions] High throughput yes yes
MARH5_HUMAN [view interactions] High throughput no no
MIC13_HUMAN [view interactions] High throughput no yes
S22A6_HUMAN [view interactions] High throughput no no
SPX3_HUMAN [view interactions] High throughput no no
P2RX2_HUMAN [view interactions] High throughput no no
OPRM_HUMAN [view entry] [view interactions] High throughput yes no
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
LCTL_HUMAN [view interactions] High throughput no no
GLR_HUMAN [view interactions] High throughput no no
S26A6_HUMAN [view interactions] High throughput no yes
C5AR1_HUMAN [view interactions] High throughput no yes
S22A8_HUMAN [view interactions] High throughput no no
SC5A6_HUMAN [view interactions] High throughput no no
CRLF2_HUMAN [view interactions] High throughput no no
S22A4_HUMAN [view interactions] High throughput no yes
GPR17_HUMAN [view interactions] High throughput no no
CREL1_HUMAN [view interactions] High throughput no yes
CD3D_HUMAN [view interactions] High throughput no no
SV2A_HUMAN [view entry] [view interactions] High throughput yes yes
CBPQ_HUMAN [view interactions] High throughput no no
IL2RA_HUMAN [view interactions] High throughput no no
V2R_HUMAN [view interactions] High throughput no no
MFAP4_HUMAN [view interactions] High throughput no no
AQP3_HUMAN [view interactions] High throughput no no
CML1_HUMAN [view interactions] High throughput no yes
GTR9_HUMAN [view interactions] High throughput no no
BSCL2_HUMAN [view interactions] High throughput no yes
S22AF_HUMAN [view interactions] High throughput no yes
OX2R_HUMAN [view interactions] High throughput no no
FFAR1_HUMAN [view interactions] High throughput no no
OTUD4_HUMAN [view interactions] High throughput no yes
SCFD1_HUMAN [view entry] [view interactions] High throughput yes yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
ERAL1_HUMAN [view interactions] High throughput no yes
MARC1_HUMAN [view interactions] High throughput no yes
OPTN_HUMAN [view interactions] High throughput no yes
S10AA_HUMAN [view interactions] High throughput no no
FIS1_HUMAN [view entry] [view interactions] High throughput yes yes
OCAD1_HUMAN [view interactions] High throughput no yes
MARH1_HUMAN [view interactions] High throughput no yes
MARH2_HUMAN [view interactions] High throughput no yes
AAAS_HUMAN [view interactions] High throughput no yes
ABCD3_HUMAN [view entry] [view interactions] High throughput yes yes
GCP60_HUMAN [view interactions] High throughput no yes
ACBD5_HUMAN [view entry] [view interactions] High throughput yes yes
ACSL3_HUMAN [view entry] [view interactions] High throughput yes yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
ELYS_HUMAN [view interactions] High throughput no yes
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
ANKL2_HUMAN [view interactions] High throughput no yes
RHG01_HUMAN [view entry] [view interactions] High throughput yes yes
ARMX3_HUMAN [view interactions] High throughput no no
ATD3A_HUMAN [view entry] [view interactions] High throughput yes yes
ATPF1_HUMAN [view interactions] High throughput no yes
AUP1_HUMAN [view interactions] High throughput no yes
BAX_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
B2L13_HUMAN [view interactions] High throughput no no
BNI3L_HUMAN [view interactions] High throughput no yes
CI072_HUMAN [view interactions] High throughput no no
CAMLG_HUMAN [view interactions] High throughput no yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
CC115_HUMAN [view interactions] High throughput no no
CCD47_HUMAN [view interactions] High throughput no yes
CDKAL_HUMAN [view interactions] High throughput no no
CHMP7_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
CLCC1_HUMAN [view interactions] High throughput no yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
DDX24_HUMAN [view interactions] High throughput no yes
DDX50_HUMAN [view interactions] High throughput no yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
EHBP1_HUMAN [view interactions] High throughput no yes
E2AK3_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
EMC3_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
EMC7_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
ERLN2_HUMAN [view entry] [view interactions] High throughput yes yes
ESYT1_HUMAN [view entry] [view interactions] High throughput yes yes
ESYT2_HUMAN [view entry] [view interactions] High throughput yes yes
EXD2_HUMAN [view interactions] High throughput no yes
FAF2_HUMAN [view interactions] High throughput no yes
FBXL4_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
GLPK_HUMAN [view entry] [view interactions] High throughput yes no
GOGA3_HUMAN [view interactions] High throughput no yes
GOGB1_HUMAN [view entry] [view interactions] High throughput yes yes
GPAT3_HUMAN [view interactions] High throughput no yes
HAX1_HUMAN [view interactions] High throughput no no
HXK1_HUMAN [view entry] [view interactions] High throughput yes yes
HM13_HUMAN [view interactions] High throughput no yes
INF2_HUMAN [view entry] [view interactions] High throughput yes yes
ITPR2_HUMAN [view interactions] High throughput no yes
ITPR3_HUMAN [view interactions] High throughput no yes
JPH1_HUMAN [view interactions] High throughput no no
KI16B_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
LBR_HUMAN [view interactions] High throughput no yes
MAN1_HUMAN [view interactions] High throughput no yes
LMAN1_HUMAN [view interactions] High throughput no yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
LMNB2_HUMAN [view entry] [view interactions] High throughput yes yes
LNP_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
LSG1_HUMAN [view interactions] High throughput no yes
MAGT1_HUMAN [view interactions] High throughput no yes
MAVS_HUMAN [view interactions] High throughput no yes
TGO1_HUMAN [view interactions] High throughput no yes
MIGA1_HUMAN [view interactions] High throughput no yes
EMC5_HUMAN [view interactions] High throughput no yes
MSPD2_HUMAN [view interactions] High throughput no yes
LYRIC_HUMAN [view entry] [view interactions] High throughput yes yes
MFR1L_HUMAN [view interactions] High throughput no yes
MYO19_HUMAN [view interactions] High throughput no yes
NBAS_HUMAN [view interactions] High throughput no yes
NDC1_HUMAN [view interactions] High throughput no yes
NFL_HUMAN [view entry] [view interactions] High throughput yes yes
NIPS1_HUMAN [view entry] [view interactions] High throughput yes yes
NIPS2_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
NU155_HUMAN [view interactions] High throughput no yes
NU160_HUMAN [view interactions] High throughput no no
NUP35_HUMAN [view interactions] High throughput no yes
PALD_HUMAN [view interactions] High throughput no yes
PHLP_HUMAN [view interactions] High throughput no yes
PDZD8_HUMAN [view interactions] High throughput no yes
PGRC2_HUMAN [view interactions] High throughput no yes
PLK1_HUMAN [view interactions] High throughput no yes
PREB_HUMAN [view interactions] High throughput no yes
KAP2_HUMAN [view entry] [view interactions] High throughput yes yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
PTN1_HUMAN [view interactions] High throughput no yes
RB3GP_HUMAN [view entry] [view interactions] High throughput yes yes
RBGPR_HUMAN [view entry] [view interactions] High throughput yes yes
RABL3_HUMAN [view interactions] High throughput no yes
MIRO2_HUMAN [view entry] [view interactions] High throughput yes yes
RMD2_HUMAN [view interactions] High throughput no yes
RMD3_HUMAN [view interactions] High throughput no yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
RRBP1_HUMAN [view entry] [view interactions] High throughput yes yes
RTN3_HUMAN [view entry] [view interactions] High throughput yes yes
SCYL1_HUMAN [view interactions] High throughput no yes
SEC13_HUMAN [view entry] [view interactions] High throughput yes yes
SC16A_HUMAN [view interactions] High throughput no yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
SC23A_HUMAN [view entry] [view interactions] High throughput yes yes
SC23B_HUMAN [view interactions] High throughput no yes
S23IP_HUMAN [view interactions] High throughput no yes
SC24A_HUMAN [view interactions] High throughput no no
SC24B_HUMAN [view interactions] High throughput no yes
SEC63_HUMAN [view interactions] High throughput no yes
SENP1_HUMAN [view interactions] High throughput no no
SENP2_HUMAN [view interactions] High throughput no yes
ZNT6_HUMAN [view interactions] High throughput no yes
ZNT9_HUMAN [view interactions] High throughput no yes
SMCR8_HUMAN [view interactions] High throughput no yes
NSMA3_HUMAN [view interactions] High throughput no yes
SNP29_HUMAN [view interactions] High throughput no yes
SNP47_HUMAN [view entry] [view interactions] High throughput yes yes
SOAT1_HUMAN [view interactions] High throughput no no
SRPRA_HUMAN [view interactions] High throughput no no
STBD1_HUMAN [view interactions] High throughput no yes
STIM1_HUMAN [view interactions] High throughput no yes
STIM2_HUMAN [view interactions] High throughput no yes
STML2_HUMAN [view entry] [view interactions] High throughput yes yes
STT3B_HUMAN [view interactions] High throughput no yes
STX5_HUMAN [view interactions] High throughput no yes
SUN1_HUMAN [view interactions] High throughput no yes
SUN2_HUMAN [view interactions] High throughput no yes
SYAP1_HUMAN [view entry] [view interactions] High throughput yes yes
SYNE2_HUMAN [view interactions] High throughput no no
TACC1_HUMAN [view entry] [view interactions] High throughput yes yes
TDRKH_HUMAN [view interactions] High throughput no no
TEX2_HUMAN [view interactions] High throughput no yes
TX264_HUMAN [view interactions] High throughput no no
TM209_HUMAN [view interactions] High throughput no no
TM214_HUMAN [view interactions] High throughput no no
LAP2A_HUMAN [view interactions] High throughput no yes
TOIP1_HUMAN [view interactions] High throughput no yes
TOIP2_HUMAN [view interactions] High throughput no no
TRABD_HUMAN [view interactions] High throughput no yes
TRAK2_HUMAN [view interactions] High throughput no yes
TRI13_HUMAN [view interactions] High throughput no no
TRIPB_HUMAN [view interactions] High throughput no yes
TRPM7_HUMAN [view interactions] High throughput no no
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
UBAC2_HUMAN [view interactions] High throughput no yes
UB2J1_HUMAN [view interactions] High throughput no yes
UBXN4_HUMAN [view interactions] High throughput no yes
UBP30_HUMAN [view interactions] High throughput no yes
UBP33_HUMAN [view interactions] High throughput no yes
VANG1_HUMAN [view interactions] High throughput no no
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
PDCD1_HUMAN [view interactions] High throughput no yes
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
APJ_HUMAN [view interactions] High throughput no yes
VEZA_HUMAN [view interactions] High throughput no yes
S15A1_HUMAN [view interactions] High throughput no no
VP13A_HUMAN [view interactions] High throughput no yes
I13R2_HUMAN [view interactions] High throughput no no
VP13C_HUMAN [view interactions] High throughput no yes
NK1R_HUMAN [view interactions] High throughput no no
VP13D_HUMAN [view interactions] High throughput no no
S22A9_HUMAN [view interactions] High throughput no no
VRK2_HUMAN [view interactions] High throughput no no
AAAT_HUMAN [view interactions] High throughput no no
WDR41_HUMAN [view interactions] High throughput no yes
SC5A8_HUMAN [view interactions] High throughput no no
WWOX_HUMAN [view interactions] High throughput no yes
S22AG_HUMAN [view interactions] High throughput no yes
YKT6_HUMAN [view interactions] High throughput no yes
PI2R_HUMAN [view interactions] High throughput no no
ZCCHV_HUMAN [view interactions] High throughput no yes
GCNT1_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
FHL3_HUMAN [view interactions] High throughput no no
FUND1_HUMAN [view interactions] High throughput no yes
REEP2_HUMAN [view interactions] High throughput no yes
S66A2_HUMAN [view interactions] High throughput no yes
NTCP_HUMAN [view interactions] High throughput no no
ODFP4_HUMAN [view interactions] High throughput no no
LAT2_HUMAN [view interactions] High throughput no no
REEP4_HUMAN [view interactions] High throughput no no
MF14B_HUMAN [view interactions] High throughput no no
SOAT_HUMAN [view interactions] High throughput no no
AQP6_HUMAN [view interactions] High throughput no no
DHB13_HUMAN [view interactions] High throughput no yes
VMA21_HUMAN [view interactions] High throughput no no
DHB11_HUMAN [view interactions] High throughput no yes
LERL1_HUMAN [view interactions] High throughput no no
TOM22_HUMAN [view interactions] High throughput no yes
SPCS1_HUMAN [view interactions] High throughput no yes
ERGI3_HUMAN [view interactions] High throughput no yes
OPA1_HUMAN [view entry] [view interactions] High throughput yes yes
MIC27_HUMAN [view entry] [view interactions] High throughput yes yes