MTX1_HUMAN
Evidence for PS localization
Functions
Involved in transport of proteins into the mitochondrion. Essential for embryonic development . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MTX1_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 52.5000 | 4 | yes |
| GO:0007005 | mitochondrion organization | 37.5000 | 5 | yes |
| GO:0061024 | membrane organization | 32.5000 | 4 | yes |
| GO:0071702 | organic substance transport | 32.5000 | 4 | yes |
| GO:0008104 | protein localization | 30.0000 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 30.0000 | 4 | yes |
| GO:0007006 | mitochondrial membrane organization | 27.5000 | 5 | yes |
| GO:0007007 | inner mitochondrial membrane organization | 27.5000 | 6 | yes |
| GO:0048522 | positive regulation of cellular process | 27.5000 | 4 | no |
| GO:0015031 | protein transport | 25.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 25.0000 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 22.5000 | 4 | no |
| GO:0022607 | cellular component assembly | 22.5000 | 4 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MTX1_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 5.0000 | 3 | no |
| DOID:700 | mitochondrial metabolism disease | 5.0000 | 3 | no |
| DOID:870 | neuropathy | 5.0000 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| TOM40_HUMAN | [view interactions] | Low throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SAM50_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD80_HUMAN | [view interactions] | High throughput | no | no |
| AQP3_HUMAN | [view interactions] | High throughput | no | no |
| RUSF1_HUMAN | [view interactions] | High throughput | no | yes |
| OX2R_HUMAN | [view interactions] | High throughput | no | no |
| MAGA8_HUMAN | [view interactions] | High throughput | no | no |
| BSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| GLR_HUMAN | [view interactions] | High throughput | no | no |
| PTH1R_HUMAN | [view interactions] | High throughput | no | no |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| MTLR_HUMAN | [view interactions] | High throughput | no | no |
| S26A6_HUMAN | [view interactions] | High throughput | no | yes |
| VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MICB_HUMAN | [view interactions] | High throughput | no | no |
| PCAT2_HUMAN | [view interactions] | High throughput | no | yes |
| P2Y10_HUMAN | [view interactions] | High throughput | no | no |
| PTH2R_HUMAN | [view interactions] | High throughput | no | no |
| EFNA4_HUMAN | [view interactions] | High throughput | no | no |
| GPR12_HUMAN | [view interactions] | High throughput | no | no |
| OPRX_HUMAN | [view interactions] | High throughput | no | no |
| HCST_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRNG_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3C_HUMAN | [view interactions] | High throughput | no | no |
| A1BG_HUMAN | [view interactions] | High throughput | no | no |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC10_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NECA1_HUMAN | [view interactions] | High throughput | no | yes |
| PLXA4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| OPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYR1_HUMAN | [view interactions] | High throughput | no | no |
| MIC27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| MIC13_HUMAN | [view interactions] | High throughput | no | yes |
| CISD3_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| LFG4_HUMAN | [view interactions] | High throughput | no | no |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| CLN8_HUMAN | [view interactions] | High throughput | no | no |
| MIC10_HUMAN | [view interactions] | High throughput | no | yes |
| KCIP4_HUMAN | [view interactions] | High throughput | no | no |
| DPA1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| CCG4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYPD3_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| EDNRA_HUMAN | [view interactions] | High throughput | no | yes |
| ADCK1_HUMAN | [view interactions] | High throughput | no | no |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPAR4_HUMAN | [view interactions] | High throughput | no | no |
| GON1_HUMAN | [view interactions] | High throughput | no | yes |
| VIPR2_HUMAN | [view interactions] | High throughput | no | no |
| GLMP_HUMAN | [view interactions] | High throughput | no | no |
| GHITM_HUMAN | [view interactions] | High throughput | no | yes |
| GTR12_HUMAN | [view interactions] | High throughput | no | yes |
| MAS_HUMAN | [view interactions] | High throughput | no | no |
| S39AC_HUMAN | [view interactions] | High throughput | no | no |
| S15A1_HUMAN | [view interactions] | High throughput | no | no |
| APJ_HUMAN | [view interactions] | High throughput | no | yes |
| SIG12_HUMAN | [view interactions] | High throughput | no | no |
| 5HT2C_HUMAN | [view interactions] | High throughput | no | no |
| TM108_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S39A9_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| SC5A6_HUMAN | [view interactions] | High throughput | no | no |
| IL2RA_HUMAN | [view interactions] | High throughput | no | no |
| SO4C1_HUMAN | [view interactions] | High throughput | no | no |
| TOM7_HUMAN | [view interactions] | Computational | no | no |
| MIC25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TRI46_HUMAN | [view interactions] | Computational | no | no |
| TOM70_HUMAN | [view interactions] | Computational | no | yes |
| MIC19_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TSP3_HUMAN | [view interactions] | Computational | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TOM20_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TM40L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | Computational | yes | yes |