MTX2_HUMAN
Evidence for PS localization
Functions
Involved in transport of proteins into the mitochondrion. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MTX2_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 53.5714 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 44.6429 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 37.5000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 37.5000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 35.7143 | 4 | no |
| GO:0007005 | mitochondrion organization | 33.9286 | 5 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 33.9286 | 4 | no |
| GO:0061024 | membrane organization | 32.1429 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 32.1429 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 32.1429 | 4 | no |
| GO:0008104 | protein localization | 30.3571 | 4 | yes |
| GO:0071702 | organic substance transport | 28.5714 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 28.5714 | 4 | no |
| GO:0010646 | regulation of cell communication | 28.5714 | 4 | no |
| GO:0010941 | regulation of cell death | 28.5714 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.7857 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.7857 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 26.7857 | 5 | no |
| GO:0071705 | nitrogen compound transport | 25.0000 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0007006 | mitochondrial membrane organization | 23.2143 | 5 | yes |
| GO:0022607 | cellular component assembly | 23.2143 | 4 | no |
| GO:0010468 | regulation of gene expression | 21.4286 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21.4286 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 21.4286 | 5 | no |
| GO:0051049 | regulation of transport | 21.4286 | 4 | no |
| GO:0015031 | protein transport | 19.6429 | 4 | yes |
| GO:0007007 | inner mitochondrial membrane organization | 17.8571 | 6 | yes |
| GO:0006839 | mitochondrial transport | 10.7143 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MTX2_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 5.3571 | 3 | no |
| DOID:870 | neuropathy | 5.3571 | 4 | no |
| DOID:1891 | optic nerve disease | 3.5714 | 6 | no |
| DOID:5656 | cranial nerve disease | 3.5714 | 5 | no |
| DOID:5723 | optic atrophy | 3.5714 | 7 | no |
| DOID:700 | mitochondrial metabolism disease | 3.5714 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MIC60_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RNF26_HUMAN | [view interactions] | High throughput | no | yes |
| TRI13_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAM3B_HUMAN | [view interactions] | High throughput | no | yes |
| EDNRA_HUMAN | [view interactions] | High throughput | no | yes |
| DOXA2_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| TRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| FAXC_HUMAN | [view interactions] | High throughput | no | no |
| PARVG_HUMAN | [view interactions] | High throughput | no | yes |
| GTR8_HUMAN | [view interactions] | High throughput | no | yes |
| GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRN4L_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P2RY8_HUMAN | [view interactions] | High throughput | no | no |
| COAA1_HUMAN | [view interactions] | High throughput | no | no |
| T184A_HUMAN | [view interactions] | High throughput | no | no |
| HUMMR_HUMAN | [view interactions] | High throughput | no | yes |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| CLPB_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARH2_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BNIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BNI3L_HUMAN | [view interactions] | High throughput | no | yes |
| CC138_HUMAN | [view interactions] | High throughput | no | yes |
| ACM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX20_HUMAN | [view interactions] | High throughput | no | no |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC49_HUMAN | [view interactions] | High throughput | no | no |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIGA1_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP_HUMAN | [view interactions] | High throughput | no | yes |
| PDCL3_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| TDRKH_HUMAN | [view interactions] | High throughput | no | no |
| TRA2B_HUMAN | [view interactions] | High throughput | no | yes |
| TRABD_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP30_HUMAN | [view interactions] | High throughput | no | yes |
| VP13D_HUMAN | [view interactions] | High throughput | no | no |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| OPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| TIM29_HUMAN | [view interactions] | High throughput | no | no |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| DNJC4_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE120_HUMAN | [view interactions] | High throughput | no | no |
| CC127_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASTE1_HUMAN | [view interactions] | High throughput | no | no |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| MTX3_HUMAN | [view interactions] | High throughput | no | yes |
| TM263_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPB2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUBB_HUMAN | [view interactions] | High throughput | no | yes |
| CEPT1_HUMAN | [view interactions] | High throughput | no | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRDC_HUMAN | [view interactions] | High throughput | no | no |
| CATAC_HUMAN | [view interactions] | High throughput | no | yes |
| MIC27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC13_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGB_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ATG2A_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| TAD2A_HUMAN | [view interactions] | High throughput | no | no |
| KASH5_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| C1QT2_HUMAN | [view interactions] | High throughput | no | yes |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLRKT_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| PARL_HUMAN | [view interactions] | High throughput | no | yes |
| YMEL1_HUMAN | [view interactions] | High throughput | no | yes |
| MIC10_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| TRAK2_HUMAN | [view interactions] | High throughput | no | yes |
| CD244_HUMAN | [view interactions] | High throughput | no | no |
| TPD52_HUMAN | [view interactions] | High throughput | no | yes |
| EI2BD_HUMAN | [view interactions] | High throughput | no | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAR19_HUMAN | [view interactions] | High throughput | no | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM5_HUMAN | [view interactions] | Computational | no | yes |
| TOM7_HUMAN | [view interactions] | Computational | no | no |
| LNP_HUMAN | [view interactions] | Computational | no | yes |
| TOM40_HUMAN | [view interactions] | Computational | no | yes |
| TMM11_HUMAN | [view interactions] | Computational | no | no |
| TOM70_HUMAN | [view interactions] | Computational | no | yes |