FIS1_HUMAN
Evidence for PS localization
Functions
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FIS1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 35.7143 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 35.7143 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.4286 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 24.2857 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 24.2857 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 24.2857 | 6 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FIS1_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 52.8571 | 4 | yes |
| GO:0008104 | protein localization | 42.8571 | 4 | yes |
| GO:0071702 | organic substance transport | 38.5714 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 37.1429 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 34.2857 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 34.2857 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 32.8571 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 32.8571 | 4 | yes |
| GO:0010646 | regulation of cell communication | 31.4286 | 4 | yes |
| GO:0015031 | protein transport | 31.4286 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 30.0000 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 30.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 28.5714 | 4 | yes |
| GO:0061024 | membrane organization | 27.1429 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 27.1429 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 22.8571 | 5 | yes |
| GO:0033365 | protein localization to organelle | 22.8571 | 5 | yes |
| GO:0051049 | regulation of transport | 22.8571 | 4 | yes |
| GO:0022607 | cellular component assembly | 21.4286 | 4 | no |
| GO:0006886 | intracellular protein transport | 21.4286 | 4 | yes |
| GO:0007005 | mitochondrion organization | 21.4286 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 21.4286 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 21.4286 | 5 | yes |
| GO:0010941 | regulation of cell death | 20.0000 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 20.0000 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 20.0000 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 20.0000 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 18.5714 | 5 | yes |
| GO:0072594 | establishment of protein localization to organelle | 17.1429 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 17.1429 | 4 | yes |
| GO:0048878 | chemical homeostasis | 17.1429 | 4 | yes |
| GO:0048284 | organelle fusion | 15.7143 | 5 | yes |
| GO:0051050 | positive regulation of transport | 15.7143 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 15.7143 | 5 | yes |
| GO:0070585 | protein localization to mitochondrion | 14.2857 | 6 | yes |
| GO:0098771 | inorganic ion homeostasis | 14.2857 | 6 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 14.2857 | 5 | yes |
| GO:0006839 | mitochondrial transport | 14.2857 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 14.2857 | 5 | yes |
| GO:0050801 | ion homeostasis | 14.2857 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 14.2857 | 6 | yes |
| GO:0055080 | cation homeostasis | 14.2857 | 6 | yes |
| GO:0006873 | cellular ion homeostasis | 12.8571 | 4 | yes |
| GO:0010821 | regulation of mitochondrion organization | 12.8571 | 6 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 12.8571 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 12.8571 | 6 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 12.8571 | 4 | yes |
| GO:0030003 | cellular cation homeostasis | 12.8571 | 5 | yes |
| GO:0048285 | organelle fission | 12.8571 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 12.8571 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 12.8571 | 5 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 12.8571 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 12.8571 | 4 | yes |
| GO:0072655 | establishment of protein localization to mitochondrion | 11.4286 | 5 | yes |
| GO:0000266 | mitochondrial fission | 11.4286 | 6 | yes |
| GO:0006605 | protein targeting | 11.4286 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 11.4286 | 6 | yes |
| GO:0023056 | positive regulation of signaling | 11.4286 | 4 | yes |
| GO:0032880 | regulation of protein localization | 11.4286 | 5 | yes |
| GO:0055065 | metal ion homeostasis | 11.4286 | 7 | yes |
| GO:0072507 | divalent inorganic cation homeostasis | 10.0000 | 7 | yes |
| GO:1903829 | positive regulation of protein localization | 10.0000 | 5 | yes |
| GO:0006875 | cellular metal ion homeostasis | 10.0000 | 6 | yes |
| GO:0008053 | mitochondrial fusion | 10.0000 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 10.0000 | 5 | yes |
| GO:0032990 | cell part morphogenesis | 10.0000 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 10.0000 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 10.0000 | 4 | yes |
| GO:0051051 | negative regulation of transport | 10.0000 | 4 | yes |
| GO:0070201 | regulation of establishment of protein localization | 8.5714 | 6 | yes |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 8.5714 | 6 | yes |
| GO:0090140 | regulation of mitochondrial fission | 8.5714 | 5 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 8.5714 | 5 | yes |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 8.5714 | 6 | yes |
| GO:0006626 | protein targeting to mitochondrion | 8.5714 | 5 | yes |
| GO:0006874 | cellular calcium ion homeostasis | 8.5714 | 7 | yes |
| GO:0009967 | positive regulation of signal transduction | 8.5714 | 5 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 8.5714 | 6 | yes |
| GO:0010822 | positive regulation of mitochondrion organization | 8.5714 | 7 | yes |
| GO:0022411 | cellular component disassembly | 8.5714 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 8.5714 | 6 | yes |
| GO:0032386 | regulation of intracellular transport | 8.5714 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 8.5714 | 7 | yes |
| GO:0051223 | regulation of protein transport | 8.5714 | 5 | yes |
| GO:0051336 | regulation of hydrolase activity | 8.5714 | 4 | yes |
| GO:0055074 | calcium ion homeostasis | 8.5714 | 8 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 7.1429 | 4 | yes |
| GO:0090141 | positive regulation of mitochondrial fission | 7.1429 | 5 | yes |
| GO:1903008 | organelle disassembly | 7.1429 | 5 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 7.1429 | 6 | yes |
| GO:0008637 | apoptotic mitochondrial changes | 7.1429 | 6 | yes |
| GO:0010942 | positive regulation of cell death | 7.1429 | 5 | yes |
| GO:0016559 | peroxisome fission | 7.1429 | 6 | yes |
| GO:0032388 | positive regulation of intracellular transport | 7.1429 | 5 | yes |
| GO:0033157 | regulation of intracellular protein transport | 7.1429 | 6 | yes |
| GO:0043065 | positive regulation of apoptotic process | 7.1429 | 7 | yes |
| GO:0043068 | positive regulation of programmed cell death | 7.1429 | 6 | yes |
| GO:0045862 | positive regulation of proteolysis | 7.1429 | 7 | yes |
| GO:0051222 | positive regulation of protein transport | 7.1429 | 5 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 7.1429 | 5 | yes |
| GO:0061726 | mitochondrion disassembly | 5.7143 | 6 | yes |
| GO:0070584 | mitochondrion morphogenesis | 5.7143 | 5 | yes |
| GO:0090316 | positive regulation of intracellular protein transport | 5.7143 | 6 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 5.7143 | 6 | yes |
| GO:1903533 | regulation of protein targeting | 5.7143 | 7 | yes |
| GO:1905475 | regulation of protein localization to membrane | 5.7143 | 6 | yes |
| GO:1905477 | positive regulation of protein localization to membrane | 5.7143 | 6 | yes |
| GO:0000422 | autophagy of mitochondrion | 5.7143 | 4 | yes |
| GO:0001836 | release of cytochrome c from mitochondria | 5.7143 | 7 | yes |
| GO:0043653 | mitochondrial fragmentation involved in apoptotic process | 5.7143 | 7 | yes |
| GO:0051560 | mitochondrial calcium ion homeostasis | 5.7143 | 8 | yes |
| GO:0090313 | regulation of protein targeting to membrane | 4.2857 | 7 | yes |
| GO:0090314 | positive regulation of protein targeting to membrane | 4.2857 | 7 | yes |
| GO:1900542 | regulation of purine nucleotide metabolic process | 4.2857 | 6 | yes |
| GO:1903578 | regulation of ATP metabolic process | 4.2857 | 7 | yes |
| GO:1905952 | regulation of lipid localization | 4.2857 | 4 | yes |
| GO:2001235 | positive regulation of apoptotic signaling pathway | 4.2857 | 6 | yes |
| GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway | 4.2857 | 7 | yes |
| GO:0006140 | regulation of nucleotide metabolic process | 4.2857 | 5 | yes |
| GO:0010952 | positive regulation of peptidase activity | 4.2857 | 6 | yes |
| GO:0019722 | calcium-mediated signaling | 4.2857 | 5 | yes |
| GO:0019932 | second-messenger-mediated signaling | 4.2857 | 4 | yes |
| GO:0032368 | regulation of lipid transport | 4.2857 | 5 | yes |
| GO:0032890 | regulation of organic acid transport | 4.2857 | 5 | yes |
| GO:0035584 | calcium-mediated signaling using intracellular calcium source | 4.2857 | 6 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 4.2857 | 6 | yes |
| GO:0052547 | regulation of peptidase activity | 4.2857 | 5 | yes |
| GO:0062014 | negative regulation of small molecule metabolic process | 2.8571 | 5 | yes |
| GO:1900543 | negative regulation of purine nucleotide metabolic process | 2.8571 | 7 | yes |
| GO:1903579 | negative regulation of ATP metabolic process | 2.8571 | 8 | yes |
| GO:1905953 | negative regulation of lipid localization | 2.8571 | 4 | yes |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 2.8571 | 7 | yes |
| GO:2000191 | regulation of fatty acid transport | 2.8571 | 6 | yes |
| GO:2000192 | negative regulation of fatty acid transport | 2.8571 | 6 | yes |
| GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 2.8571 | 8 | yes |
| GO:0010950 | positive regulation of endopeptidase activity | 2.8571 | 7 | yes |
| GO:0032369 | negative regulation of lipid transport | 2.8571 | 5 | yes |
| GO:0032469 | endoplasmic reticulum calcium ion homeostasis | 2.8571 | 8 | yes |
| GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration | 2.8571 | 9 | yes |
| GO:0032891 | negative regulation of organic acid transport | 2.8571 | 5 | yes |
| GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 2.8571 | 9 | yes |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 2.8571 | 8 | yes |
| GO:0045980 | negative regulation of nucleotide metabolic process | 2.8571 | 6 | yes |
| GO:0051561 | positive regulation of mitochondrial calcium ion concentration | 2.8571 | 9 | yes |
| GO:0052548 | regulation of endopeptidase activity | 2.8571 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in FIS1_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 8.5714 | 3 | no |
| DOID:870 | neuropathy | 8.5714 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 5.7143 | 6 | no |
| DOID:440 | neuromuscular disease | 5.7143 | 5 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 4.2857 | 7 | no |
| DOID:331 | central nervous system disease | 4.2857 | 3 | no |
| DOID:1891 | optic nerve disease | 2.8571 | 6 | no |
| DOID:5656 | cranial nerve disease | 2.8571 | 5 | no |
| DOID:5723 | optic atrophy | 2.8571 | 7 | no |
| DOID:0050543 | Charcot-Marie-Tooth disease intermediate type | 2.8571 | 7 | no |
| DOID:1289 | neurodegenerative disease | 2.8571 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NOD2_HUMAN | [view interactions] | Low throughput | no | yes |
| MARH5_HUMAN | [view interactions] | Low throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAP31_HUMAN | [view interactions] | Low throughput | no | yes |
| MID51_HUMAN | [view interactions] | Low throughput | no | no |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| PX11A_HUMAN | [view interactions] | Low throughput | no | no |
| PX11B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PX11C_HUMAN | [view interactions] | Low throughput | no | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASP8_HUMAN | [view interactions] | Low throughput | no | yes |
| ATPB_HUMAN | [view interactions] | Low throughput | no | yes |
| GDAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBC15_HUMAN | [view interactions] | Low throughput | no | yes |
| FIS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NOS3_HUMAN | [view interactions] | High throughput | no | no |
| CREB3_HUMAN | [view interactions] | High throughput | no | no |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| KASH5_HUMAN | [view interactions] | High throughput | no | yes |
| F210B_HUMAN | [view interactions] | High throughput | no | yes |
| TM14B_HUMAN | [view interactions] | High throughput | no | no |
| FFAR2_HUMAN | [view interactions] | High throughput | no | yes |
| TMPPE_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| JAGN1_HUMAN | [view interactions] | High throughput | no | no |
| KCNJ6_HUMAN | [view interactions] | High throughput | no | no |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| ABHD6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCN3B_HUMAN | [view interactions] | High throughput | no | no |
| RNK_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| PIGP_HUMAN | [view interactions] | High throughput | no | yes |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| APH1A_HUMAN | [view interactions] | High throughput | no | yes |
| F209A_HUMAN | [view interactions] | High throughput | no | no |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| VKOR1_HUMAN | [view interactions] | High throughput | no | yes |
| SPCS1_HUMAN | [view interactions] | High throughput | no | yes |
| UT1_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| AT12A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VP13A_HUMAN | [view interactions] | High throughput | no | yes |
| NJMU_HUMAN | [view interactions] | High throughput | no | yes |
| BIG3_HUMAN | [view interactions] | High throughput | no | yes |
| UBP24_HUMAN | [view interactions] | High throughput | no | yes |
| QSOX1_HUMAN | [view interactions] | High throughput | no | no |
| RAB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| DCNL5_HUMAN | [view interactions] | High throughput | no | yes |
| F91A1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB24_HUMAN | [view interactions] | High throughput | no | no |
| EVI5L_HUMAN | [view interactions] | High throughput | no | yes |
| HEAT6_HUMAN | [view interactions] | High throughput | no | no |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRF2_HUMAN | [view interactions] | High throughput | no | yes |
| URFB1_HUMAN | [view interactions] | High throughput | no | no |
| MCAT_HUMAN | [view interactions] | High throughput | no | yes |
| RBGP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZFY26_HUMAN | [view interactions] | High throughput | no | yes |
| TARB1_HUMAN | [view interactions] | High throughput | no | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| PLAP_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AQP3_HUMAN | [view interactions] | High throughput | no | no |
| DYLT4_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| PEX5_HUMAN | [view interactions] | High throughput | no | yes |
| S22A1_HUMAN | [view interactions] | High throughput | no | yes |
| S22A2_HUMAN | [view interactions] | High throughput | no | no |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELAV2_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| MARH2_HUMAN | [view interactions] | High throughput | no | yes |
| ABCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCP60_HUMAN | [view interactions] | High throughput | no | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANKL2_HUMAN | [view interactions] | High throughput | no | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARM10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMX2_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| ATAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5J_HUMAN | [view interactions] | High throughput | no | yes |
| VAS1_HUMAN | [view interactions] | High throughput | no | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPF1_HUMAN | [view interactions] | High throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B2L13_HUMAN | [view interactions] | High throughput | no | no |
| CI072_HUMAN | [view interactions] | High throughput | no | no |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| CDCA3_HUMAN | [view interactions] | High throughput | no | no |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| CHMP7_HUMAN | [view interactions] | High throughput | no | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCC1_HUMAN | [view interactions] | High throughput | no | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC3_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| FBXL4_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLPK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPAT1_HUMAN | [view interactions] | High throughput | no | no |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LSG1_HUMAN | [view interactions] | High throughput | no | yes |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIGA1_HUMAN | [view interactions] | High throughput | no | yes |
| MLX_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR1_HUMAN | [view interactions] | High throughput | no | yes |
| MFR1L_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR2_HUMAN | [view interactions] | High throughput | no | no |
| MTMR3_HUMAN | [view interactions] | High throughput | no | no |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTX3_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| NBAS_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PALD_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP_HUMAN | [view interactions] | High throughput | no | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| PEX1_HUMAN | [view interactions] | High throughput | no | no |
| PEX19_HUMAN | [view interactions] | High throughput | no | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| PEX6_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCL_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| RB3GP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBGPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNBP6_HUMAN | [view interactions] | High throughput | no | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| RN213_HUMAN | [view interactions] | High throughput | no | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SENP2_HUMAN | [view interactions] | High throughput | no | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMCR8_HUMAN | [view interactions] | High throughput | no | yes |
| SNP47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| STBD1_HUMAN | [view interactions] | High throughput | no | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| SYAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TACC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TDRKH_HUMAN | [view interactions] | High throughput | no | no |
| TEX2_HUMAN | [view interactions] | High throughput | no | yes |
| TM209_HUMAN | [view interactions] | High throughput | no | no |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRABD_HUMAN | [view interactions] | High throughput | no | yes |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP30_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPE39_HUMAN | [view interactions] | High throughput | no | yes |
| VMA21_HUMAN | [view interactions] | High throughput | no | no |
| VP13D_HUMAN | [view interactions] | High throughput | no | no |
| VRK2_HUMAN | [view interactions] | High throughput | no | no |
| WDR41_HUMAN | [view interactions] | High throughput | no | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| YMEL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| ABCD1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PEX26_HUMAN | [view interactions] | Computational | no | yes |
| DENR_HUMAN | [view interactions] | Computational | no | yes |
| PINK1_HUMAN | [view interactions] | Computational | no | yes |
| ABCD2_HUMAN | [view interactions] | Computational | no | no |
| PEX2_HUMAN | [view interactions] | Computational | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TOM20_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MFN1_HUMAN | [view interactions] | Computational | no | yes |
| PXMP4_HUMAN | [view interactions] | Computational | no | yes |
| PM34_HUMAN | [view interactions] | Computational | no | yes |
| MID49_HUMAN | [view interactions] | Computational | no | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| OPA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MFN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PEX13_HUMAN | [view interactions] | Computational | no | yes |
| PEX14_HUMAN | [view interactions] | Computational | no | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PEX16_HUMAN | [view interactions] | Computational | no | yes |
| PXMP2_HUMAN | [view interactions] | Computational | no | no |