Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MIRO2_HUMAN

Mitochondrial GTPase involved in mitochondrial trafficking (PubMed, PubMed). Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (PubMed). [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in MIRO2_HUMAN
GO:0017076 purine nucleotide binding 31.3953 4 yes
GO:0032555 purine ribonucleotide binding 31.3953 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.9070 4 yes
GO:0046872 metal ion binding 22.0930 4 yes
GO:0016462 pyrophosphatase activity 17.4419 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 17.4419 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 17.4419 6 yes
GO:0003924 GTPase activity 13.9535 7 yes
GO:0005525 GTP binding 13.9535 5 yes
GO:0019001 guanyl nucleotide binding 13.9535 5 yes
GO:0032561 guanyl ribonucleotide binding 13.9535 5 yes
GO:0005509 calcium ion binding 6.9767 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MIRO2_HUMAN
GO:0006996 organelle organization 46.5116 4 yes
GO:0048522 positive regulation of cellular process 36.0465 4 no
GO:0031323 regulation of cellular metabolic process 34.8837 4 no
GO:0051171 regulation of nitrogen compound metabolic process 32.5581 4 no
GO:0080090 regulation of primary metabolic process 32.5581 4 no
GO:0060255 regulation of macromolecule metabolic process 32.5581 4 no
GO:0008104 protein localization 31.3953 4 no
GO:0071702 organic substance transport 29.0698 4 no
GO:0048523 negative regulation of cellular process 29.0698 4 no
GO:0010646 regulation of cell communication 27.9070 4 no
GO:0061024 membrane organization 26.7442 4 yes
GO:0009893 positive regulation of metabolic process 26.7442 4 no
GO:0051128 regulation of cellular component organization 24.4186 4 yes
GO:0022607 cellular component assembly 24.4186 4 no
GO:0071705 nitrogen compound transport 24.4186 4 no
GO:0009966 regulation of signal transduction 24.4186 4 no
GO:0010604 positive regulation of macromolecule metabolic process 23.2558 5 no
GO:0009892 negative regulation of metabolic process 22.0930 4 no
GO:0051246 regulation of protein metabolic process 22.0930 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 22.0930 5 no
GO:0007005 mitochondrion organization 20.9302 5 yes
GO:0033043 regulation of organelle organization 20.9302 5 yes
GO:0015031 protein transport 20.9302 4 no
GO:0033365 protein localization to organelle 20.9302 5 no
GO:0031324 negative regulation of cellular metabolic process 20.9302 5 no
GO:0010468 regulation of gene expression 20.9302 5 no
GO:0010941 regulation of cell death 20.9302 4 no
GO:0007006 mitochondrial membrane organization 11.6279 5 yes
GO:0010821 regulation of mitochondrion organization 9.3023 6 yes
GO:0007264 small GTPase mediated signal transduction 6.9767 4 yes
GO:0008637 apoptotic mitochondrial changes 6.9767 6 yes
GO:0010970 transport along microtubule 4.6512 4 yes
GO:0030705 cytoskeleton-dependent intracellular transport 4.6512 4 yes
GO:0099111 microtubule-based transport 4.6512 4 yes
GO:0072384 organelle transport along microtubule 3.4884 4 yes
GO:0034643 establishment of mitochondrion localization, microtubule-mediated 2.3256 4 yes
GO:0035794 positive regulation of mitochondrial membrane permeability 2.3256 5 yes
GO:0046902 regulation of mitochondrial membrane permeability 2.3256 4 yes
GO:0047497 mitochondrion transport along microtubule 2.3256 5 yes
GO:0051654 establishment of mitochondrion localization 2.3256 4 yes
GO:0097345 mitochondrial outer membrane permeabilization 2.3256 7 yes
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 2.3256 5 yes
GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 2.3256 6 yes
GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 2.3256 6 yes
GO:1905710 positive regulation of membrane permeability 2.3256 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in MIRO2_HUMAN
DOID:574 peripheral nervous system disease 4.6512 3 no
DOID:870 neuropathy 4.6512 4 no
DOID:10595 Charcot-Marie-Tooth disease 3.4884 6 no
DOID:440 neuromuscular disease 3.4884 5 no
DOID:1289 neurodegenerative disease 2.3256 4 no
DOID:331 central nervous system disease 2.3256 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TRAK2_HUMAN [view interactions] Low throughput no yes
TRAK1_HUMAN [view interactions] Low throughput no yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
PINK1_HUMAN [view interactions] Low throughput no yes
HUMMR_HUMAN [view interactions] Low throughput no yes
BRD8_HUMAN [view interactions] High throughput no yes
SP100_HUMAN [view interactions] High throughput no no
TAF1_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
DD19B_HUMAN [view interactions] High throughput no yes
FFAR1_HUMAN [view interactions] High throughput no no
NXPH1_HUMAN [view interactions] High throughput no no
KLK5_HUMAN [view interactions] High throughput no no
NXPH2_HUMAN [view interactions] High throughput no no
DOCK5_HUMAN [view entry] [view interactions] High throughput yes no
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
DKKL1_HUMAN [view interactions] High throughput no no
PAR2_HUMAN [view entry] [view interactions] High throughput yes yes
FND11_HUMAN [view interactions] High throughput no no
PPTC7_HUMAN [view interactions] High throughput no yes
TSHR_HUMAN [view interactions] High throughput no no
EFNA2_HUMAN [view interactions] High throughput no no
S1PR1_HUMAN [view interactions] High throughput no no
APJ_HUMAN [view interactions] High throughput no yes
ASB14_HUMAN [view interactions] High throughput no no
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
GPR45_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
TMPS4_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
TECR_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
OXA1L_HUMAN [view interactions] High throughput no yes
NDUS7_HUMAN [view entry] [view interactions] High throughput yes no
HNRPF_HUMAN [view interactions] High throughput no yes
SRSF5_HUMAN [view interactions] High throughput no yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPR_HUMAN [view interactions] High throughput no yes
MIA40_HUMAN [view interactions] High throughput no yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
DHX9_HUMAN [view interactions] High throughput no yes
RL9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS8_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
SAM50_HUMAN [view entry] [view interactions] High throughput yes yes
PTH2_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
DBLOH_HUMAN [view interactions] High throughput no no
EXD2_HUMAN [view interactions] High throughput no yes
FBXL4_HUMAN [view interactions] High throughput no yes
FIS1_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
HAX1_HUMAN [view interactions] High throughput no no
MARH5_HUMAN [view interactions] High throughput no no
MAVS_HUMAN [view interactions] High throughput no yes
MFN2_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH1_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
MTX2_HUMAN [view entry] [view interactions] High throughput yes yes
OCAD1_HUMAN [view interactions] High throughput no yes
PTN1_HUMAN [view interactions] High throughput no yes
MARH1_HUMAN [view interactions] High throughput no yes
MARH2_HUMAN [view interactions] High throughput no yes
AAAS_HUMAN [view interactions] High throughput no yes
ABCD3_HUMAN [view entry] [view interactions] High throughput yes yes
ACBD5_HUMAN [view entry] [view interactions] High throughput yes yes
ACSL3_HUMAN [view entry] [view interactions] High throughput yes yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK2_HUMAN [view interactions] High throughput no yes
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
ALMS1_HUMAN [view interactions] High throughput no no
ANKL2_HUMAN [view interactions] High throughput no yes
APBB1_HUMAN [view interactions] High throughput no yes
ARFG3_HUMAN [view entry] [view interactions] High throughput yes no
ARM10_HUMAN [view entry] [view interactions] High throughput yes yes
ARMX2_HUMAN [view interactions] High throughput no yes
ARMX3_HUMAN [view interactions] High throughput no no
VAS1_HUMAN [view interactions] High throughput no yes
RENR_HUMAN [view entry] [view interactions] High throughput yes yes
VATF_HUMAN [view interactions] High throughput no yes
ATPF1_HUMAN [view interactions] High throughput no yes
AUP1_HUMAN [view interactions] High throughput no yes
B2L13_HUMAN [view interactions] High throughput no no
BNI3L_HUMAN [view interactions] High throughput no yes
BUB1_HUMAN [view interactions] High throughput no no
CA198_HUMAN [view interactions] High throughput no yes
C2C4C_HUMAN [view entry] [view interactions] High throughput yes no
CI072_HUMAN [view interactions] High throughput no no
CAMLG_HUMAN [view interactions] High throughput no yes
CC115_HUMAN [view interactions] High throughput no no
CCD47_HUMAN [view interactions] High throughput no yes
CDCA3_HUMAN [view interactions] High throughput no no
CDKAL_HUMAN [view interactions] High throughput no no
CENPE_HUMAN [view interactions] High throughput no no
CENPF_HUMAN [view interactions] High throughput no no
MIC19_HUMAN [view entry] [view interactions] High throughput yes yes
CHMP5_HUMAN [view interactions] High throughput no yes
CHMP7_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
CLCC1_HUMAN [view interactions] High throughput no yes
CRBG3_HUMAN [view interactions] High throughput no no
CYB5B_HUMAN [view entry] [view interactions] High throughput yes yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
DYST_HUMAN [view entry] [view interactions] High throughput yes yes
EHBP1_HUMAN [view interactions] High throughput no yes
4ET_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
EMC3_HUMAN [view interactions] High throughput no yes
EMC8_HUMAN [view interactions] High throughput no no
ESYT1_HUMAN [view entry] [view interactions] High throughput yes yes
ESYT2_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC4_HUMAN [view entry] [view interactions] High throughput yes yes
FAF2_HUMAN [view interactions] High throughput no yes
FA83B_HUMAN [view interactions] High throughput no no
FIGL1_HUMAN [view interactions] High throughput no yes
FUND2_HUMAN [view interactions] High throughput no yes
GLPK_HUMAN [view entry] [view interactions] High throughput yes no
GOGA3_HUMAN [view interactions] High throughput no yes
ASTRA_HUMAN [view interactions] High throughput no no
HXK1_HUMAN [view entry] [view interactions] High throughput yes yes
HXK2_HUMAN [view interactions] High throughput no yes
DHB4_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
INF2_HUMAN [view entry] [view interactions] High throughput yes yes
ITPR3_HUMAN [view interactions] High throughput no yes
JPH1_HUMAN [view interactions] High throughput no no
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
K1671_HUMAN [view interactions] High throughput no yes
KI16B_HUMAN [view interactions] High throughput no yes
LARP4_HUMAN [view interactions] High throughput no yes
MAN1_HUMAN [view interactions] High throughput no yes
LMAN1_HUMAN [view interactions] High throughput no yes
LRC49_HUMAN [view interactions] High throughput no no
LSG1_HUMAN [view interactions] High throughput no yes
MACOI_HUMAN [view interactions] High throughput no no
MFF_HUMAN [view entry] [view interactions] High throughput yes yes
TGO1_HUMAN [view interactions] High throughput no yes
MIGA1_HUMAN [view interactions] High throughput no yes
MINY4_HUMAN [view interactions] High throughput no yes
MLX_HUMAN [view interactions] High throughput no yes
LYRIC_HUMAN [view entry] [view interactions] High throughput yes yes
MTFR1_HUMAN [view interactions] High throughput no yes
MFR1L_HUMAN [view interactions] High throughput no yes
MTFR2_HUMAN [view interactions] High throughput no no
MTMR3_HUMAN [view interactions] High throughput no no
MTX3_HUMAN [view interactions] High throughput no yes
NAV1_HUMAN [view interactions] High throughput no yes
NDC1_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
NU107_HUMAN [view interactions] High throughput no no
NU133_HUMAN [view interactions] High throughput no yes
PALD_HUMAN [view interactions] High throughput no yes
PHLP_HUMAN [view interactions] High throughput no yes
PDZD8_HUMAN [view interactions] High throughput no yes
PEX1_HUMAN [view interactions] High throughput no no
PX11B_HUMAN [view entry] [view interactions] High throughput yes yes
PEX14_HUMAN [view interactions] High throughput no yes
PEX19_HUMAN [view interactions] High throughput no yes
PEX5_HUMAN [view interactions] High throughput no yes
PGRC2_HUMAN [view interactions] High throughput no yes
PLD6_HUMAN [view interactions] High throughput no yes
PREB_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
KAP2_HUMAN [view entry] [view interactions] High throughput yes yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
PRSR1_HUMAN [view interactions] High throughput no yes
PRR11_HUMAN [view interactions] High throughput no no
TRUA_HUMAN [view interactions] High throughput no yes
RAB13_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7L_HUMAN [view interactions] High throughput no yes
RAB3B_HUMAN [view interactions] High throughput no no
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
RABL3_HUMAN [view interactions] High throughput no yes
RNBP6_HUMAN [view interactions] High throughput no yes
RAVR1_HUMAN [view interactions] High throughput no yes
RMD3_HUMAN [view interactions] High throughput no yes
ZFYV9_HUMAN [view interactions] High throughput no yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
SAS6_HUMAN [view interactions] High throughput no no
SCFD1_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK4_HUMAN [view interactions] High throughput no no
SCYL2_HUMAN [view interactions] High throughput no yes
S38A1_HUMAN [view interactions] High throughput no yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
MYO19_HUMAN [view interactions] High throughput no yes
SEBP2_HUMAN [view interactions] High throughput no yes
FKRP_HUMAN [view interactions] High throughput no yes
SLAI1_HUMAN [view interactions] High throughput no no
RM20_HUMAN [view interactions] High throughput no yes
ACATN_HUMAN [view interactions] High throughput no yes
SGPP1_HUMAN [view interactions] High throughput no no
SMCR8_HUMAN [view interactions] High throughput no yes
SARM1_HUMAN [view interactions] High throughput no yes
SIM12_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
NSMA3_HUMAN [view interactions] High throughput no yes
BTAF1_HUMAN [view interactions] High throughput no no
SNP29_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
SNP47_HUMAN [view entry] [view interactions] High throughput yes yes
MIC27_HUMAN [view entry] [view interactions] High throughput yes yes
SOAT1_HUMAN [view interactions] High throughput no no
COQ9_HUMAN [view interactions] High throughput no yes
JIP4_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
SPCS3_HUMAN [view interactions] High throughput no yes
CNR2_HUMAN [view interactions] High throughput no yes
SPTN5_HUMAN [view interactions] High throughput no no
MOT11_HUMAN [view interactions] High throughput no no
STBD1_HUMAN [view interactions] High throughput no yes
E2F3_HUMAN [view interactions] High throughput no no
STIM1_HUMAN [view interactions] High throughput no yes
PTN5_HUMAN [view entry] [view interactions] High throughput yes yes
STX5_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
SUN1_HUMAN [view interactions] High throughput no yes
HG2A_HUMAN [view interactions] High throughput no yes
SYNE1_HUMAN [view entry] [view interactions] High throughput yes yes
P2RY6_HUMAN [view interactions] High throughput no no
TACC1_HUMAN [view entry] [view interactions] High throughput yes yes
TR10A_HUMAN [view interactions] High throughput no no
TACC2_HUMAN [view interactions] High throughput no yes
BCKD_HUMAN [view entry] [view interactions] High throughput yes yes
TDRKH_HUMAN [view interactions] High throughput no no
ADCK2_HUMAN [view interactions] High throughput no yes
TEX2_HUMAN [view interactions] High throughput no yes
ULK4_HUMAN [view interactions] High throughput no yes
TIDC1_HUMAN [view interactions] High throughput no yes
SP7_HUMAN [view interactions] High throughput no no
TM209_HUMAN [view interactions] High throughput no no
INSR_HUMAN [view interactions] High throughput no yes
TNR6C_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
TOIP1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
TRABD_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
TRI13_HUMAN [view interactions] High throughput no no
TM14B_HUMAN [view interactions] High throughput no no
TRPM7_HUMAN [view interactions] High throughput no no
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
TTC17_HUMAN [view interactions] High throughput no yes
TM86B_HUMAN [view interactions] High throughput no no
TTK_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
TUT4_HUMAN [view interactions] High throughput no yes
COX14_HUMAN [view interactions] High throughput no yes
UBXN4_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
UBP30_HUMAN [view interactions] High throughput no yes
PLRKT_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
TOM20_HUMAN [view entry] [view interactions] High throughput yes yes
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
TOM22_HUMAN [view interactions] High throughput no yes
VEZA_HUMAN [view interactions] High throughput no yes
FGFR3_HUMAN [view interactions] High throughput no yes
SPE39_HUMAN [view interactions] High throughput no yes
LMTK1_HUMAN [view interactions] High throughput no yes
VMA21_HUMAN [view interactions] High throughput no no
LMTK3_HUMAN [view entry] [view interactions] High throughput yes yes
VP13C_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view interactions] High throughput no no
VP13D_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
VP33B_HUMAN [view interactions] High throughput no yes
VRK2_HUMAN [view interactions] High throughput no no
VTA1_HUMAN [view entry] [view interactions] High throughput yes yes
RING2_HUMAN [view interactions] High throughput no yes
WDR41_HUMAN [view interactions] High throughput no yes
MIRO1_HUMAN [view entry] [view interactions] High throughput yes yes
YKT6_HUMAN [view interactions] High throughput no yes
XPR1_HUMAN [view interactions] High throughput no yes
ZCCHV_HUMAN [view interactions] High throughput no yes
WDFY3_HUMAN [view interactions] High throughput no yes
S2546_HUMAN [view entry] [view interactions] High throughput yes yes
AT2B2_HUMAN [view entry] [view interactions] High throughput yes yes
TIM29_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
EGLN3_HUMAN [view interactions] High throughput no no
PXMP2_HUMAN [view interactions] High throughput no no
TPTE_HUMAN [view interactions] High throughput no no
BROMI_HUMAN [view interactions] High throughput no no
UB2R1_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
TM41B_HUMAN [view interactions] High throughput no yes
FXRD1_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
S15A3_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
CHM4C_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes