SKT_HUMAN
Required for normal development of intervertebral disks. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SKT_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 33.3333 | 4 | no |
GO:0019901 | protein kinase binding | 28.5714 | 5 | no |
GO:0003723 | RNA binding | 26.1905 | 4 | no |
GO:0017076 | purine nucleotide binding | 23.8095 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 21.4286 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 21.4286 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SKT_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 71.4286 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 61.9048 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 54.7619 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 54.7619 | 4 | no |
GO:0051128 | regulation of cellular component organization | 52.3810 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 52.3810 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 52.3810 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 50.0000 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
GO:0048523 | negative regulation of cellular process | 47.6190 | 4 | no |
GO:0010468 | regulation of gene expression | 42.8571 | 5 | no |
GO:0022607 | cellular component assembly | 42.8571 | 4 | no |
GO:0010646 | regulation of cell communication | 42.8571 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 42.8571 | 5 | no |
GO:0008104 | protein localization | 40.4762 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 40.4762 | 6 | no |
GO:0006996 | organelle organization | 38.0952 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 38.0952 | 5 | no |
GO:0031399 | regulation of protein modification process | 38.0952 | 6 | no |
GO:0048584 | positive regulation of response to stimulus | 38.0952 | 4 | no |
GO:0009966 | regulation of signal transduction | 35.7143 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
GO:0007010 | cytoskeleton organization | 30.9524 | 5 | no |
GO:0010647 | positive regulation of cell communication | 30.9524 | 5 | no |
GO:0030030 | cell projection organization | 30.9524 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 30.9524 | 7 | no |
GO:0019220 | regulation of phosphate metabolic process | 30.9524 | 6 | no |
GO:0042325 | regulation of phosphorylation | 30.9524 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 30.9524 | 5 | no |
GO:0036211 | protein modification process | 28.5714 | 4 | no |
GO:0043412 | macromolecule modification | 28.5714 | 4 | no |
GO:0010628 | positive regulation of gene expression | 28.5714 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.5714 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 28.5714 | 4 | no |
GO:0023056 | positive regulation of signaling | 28.5714 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 28.5714 | 7 | no |
GO:0042127 | regulation of cell population proliferation | 26.1905 | 4 | no |
GO:0051049 | regulation of transport | 26.1905 | 4 | no |
GO:0033043 | regulation of organelle organization | 26.1905 | 5 | no |
GO:0071702 | organic substance transport | 26.1905 | 4 | no |
GO:0071705 | nitrogen compound transport | 26.1905 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 26.1905 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 26.1905 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 26.1905 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 26.1905 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 26.1905 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 23.8095 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 23.8095 | 5 | no |
GO:0097435 | supramolecular fiber organization | 23.8095 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 23.8095 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.8095 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 23.8095 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 23.8095 | 6 | no |
GO:0080134 | regulation of response to stress | 23.8095 | 4 | no |
GO:0071310 | cellular response to organic substance | 23.8095 | 4 | no |
GO:0051094 | positive regulation of developmental process | 21.4286 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 21.4286 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.4286 | 4 | no |
GO:0034330 | cell junction organization | 21.4286 | 4 | no |
GO:0051493 | regulation of cytoskeleton organization | 21.4286 | 6 | no |
GO:0009894 | regulation of catabolic process | 21.4286 | 4 | no |
GO:0010941 | regulation of cell death | 21.4286 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.4286 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.4286 | 6 | no |
GO:0080135 | regulation of cellular response to stress | 21.4286 | 4 | no |
GO:2000112 | regulation of cellular macromolecule biosynthetic process | 21.4286 | 6 | no |
GO:0001934 | positive regulation of protein phosphorylation | 21.4286 | 8 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 21.4286 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 21.4286 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 21.4286 | 7 | no |
GO:1901699 | cellular response to nitrogen compound | 21.4286 | 4 | no |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in SKT_HUMAN |
---|---|---|---|---|
DOID:1289 | neurodegenerative disease | 7.1429 | 4 | no |
DOID:231 | motor neuron disease | 7.1429 | 5 | no |
DOID:331 | central nervous system disease | 7.1429 | 3 | no |
DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 4.7619 | 7 | no |
DOID:12377 | spinal muscular atrophy | 4.7619 | 6 | no |
DOID:332 | amyotrophic lateral sclerosis | 4.7619 | 6 | no |
DOID:0111962 | combined immunodeficiency | 4.7619 | 4 | no |
DOID:612 | primary immunodeficiency disease | 4.7619 | 3 | no |
DOID:627 | severe combined immunodeficiency | 4.7619 | 5 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
MARE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FHL2_HUMAN | [view interactions] | High throughput | no | yes |
NANOG_HUMAN | [view interactions] | High throughput | no | no |
NANP8_HUMAN | [view interactions] | High throughput | no | no |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
NEK4_HUMAN | [view interactions] | High throughput | no | yes |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VINEX_HUMAN | [view interactions] | High throughput | no | no |
NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EXOS5_HUMAN | [view interactions] | High throughput | no | yes |
TEX11_HUMAN | [view interactions] | High throughput | no | no |
GCC1_HUMAN | [view interactions] | High throughput | no | yes |
K1C15_HUMAN | [view interactions] | High throughput | no | no |
FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRK1_HUMAN | [view interactions] | High throughput | no | yes |
CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
NINL_HUMAN | [view interactions] | High throughput | no | yes |
HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSBP1_HUMAN | [view interactions] | High throughput | no | no |
VPS52_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SIAH1_HUMAN | [view interactions] | High throughput | no | yes |
TRAF1_HUMAN | [view interactions] | High throughput | no | no |
K1H1_HUMAN | [view interactions] | High throughput | no | no |
PTK6_HUMAN | [view interactions] | High throughput | no | yes |
EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ALKB7_HUMAN | [view interactions] | High throughput | no | yes |
TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
RINT1_HUMAN | [view interactions] | High throughput | no | yes |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
K1C27_HUMAN | [view interactions] | High throughput | no | no |
INCA1_HUMAN | [view interactions] | High throughput | no | no |
GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MICU2_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
TRIB2_HUMAN | [view interactions] | High throughput | no | yes |
WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
ERR2_HUMAN | [view interactions] | High throughput | no | no |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP1_HUMAN | [view interactions] | High throughput | no | yes |
WDR48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
FOXO3_HUMAN | [view interactions] | High throughput | no | yes |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
RND3_HUMAN | [view interactions] | High throughput | no | no |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CPNE4_HUMAN | [view interactions] | High throughput | no | no |
CPNE1_HUMAN | [view interactions] | High throughput | no | no |
HNRLL_HUMAN | [view interactions] | High throughput | no | yes |
SYNC_HUMAN | [view interactions] | High throughput | no | yes |
NAL14_HUMAN | [view interactions] | High throughput | no | no |
NOS3_HUMAN | [view interactions] | High throughput | no | no |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
NIN_HUMAN | [view interactions] | High throughput | no | no |
PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LZTS2_HUMAN | [view interactions] | High throughput | no | no |
MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41LA_HUMAN | [view interactions] | High throughput | no | yes |
FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
K1C18_HUMAN | [view interactions] | High throughput | no | no |
LATS1_HUMAN | [view interactions] | High throughput | no | yes |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AFAD_HUMAN | [view interactions] | High throughput | no | yes |
NDC80_HUMAN | [view interactions] | High throughput | no | no |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAXI_HUMAN | [view interactions] | High throughput | no | yes |
RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STIL_HUMAN | [view interactions] | High throughput | no | no |
SYNE3_HUMAN | [view interactions] | High throughput | no | no |
VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZYX_HUMAN | [view interactions] | High throughput | no | no |
NAA40_HUMAN | [view interactions] | High throughput | no | no |
RNF43_HUMAN | [view interactions] | High throughput | no | yes |
IDH3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |