Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DYST_HUMAN

regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. [View more on UniProt]

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No data found.

ELM instance Name Type Start End Partner
ELMI001286 LIG_SxIP_EBH_1 LIG 7545 7558 -
ELMI001286 LIG_SxIP_EBH_1 LIG 7545 7558 -

Molecular function

Term Name % Distance from the top of the tree Annotated in DYST_HUMAN
GO:0043168 anion binding 32.6923 4 no
GO:0000166 nucleotide binding 31.7308 4 no
GO:0017076 purine nucleotide binding 30.7692 5 no
GO:0032555 purine ribonucleotide binding 29.8077 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.8462 4 no
GO:0019900 kinase binding 27.8846 4 no
GO:0019901 protein kinase binding 27.8846 5 no
GO:0043169 cation binding 23.0769 4 yes
GO:0046872 metal ion binding 22.1154 5 yes
GO:0003779 actin binding 20.1923 4 yes
GO:0030554 adenyl nucleotide binding 20.1923 6 no
GO:0015631 tubulin binding 13.4615 4 yes
GO:0005509 calcium ion binding 12.5000 6 yes
GO:0008017 microtubule binding 9.6154 5 yes
GO:0042803 protein homodimerization activity 6.7308 4 yes
GO:0051010 microtubule plus-end binding 4.8077 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DYST_HUMAN
GO:0048522 positive regulation of cellular process 65.3846 4 no
GO:0051128 regulation of cellular component organization 55.7692 4 no
GO:0048523 negative regulation of cellular process 53.8462 4 no
GO:0060255 regulation of macromolecule metabolic process 51.9231 4 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 47.1154 4 no
GO:0010646 regulation of cell communication 46.1538 4 no
GO:0008104 protein localization 44.2308 4 no
GO:0006996 organelle organization 43.2692 4 yes
GO:0009893 positive regulation of metabolic process 41.3462 4 no
GO:0010604 positive regulation of macromolecule metabolic process 39.4231 5 no
GO:0022607 cellular component assembly 37.5000 4 yes
GO:0009966 regulation of signal transduction 37.5000 4 no
GO:0051246 regulation of protein metabolic process 36.5385 5 no
GO:0009889 regulation of biosynthetic process 35.5769 4 no
GO:0010468 regulation of gene expression 35.5769 6 no
GO:0010556 regulation of macromolecule biosynthetic process 35.5769 5 no
GO:0031326 regulation of cellular biosynthetic process 35.5769 5 no
GO:0031325 positive regulation of cellular metabolic process 33.6538 5 no
GO:0051049 regulation of transport 33.6538 4 no
GO:0030030 cell projection organization 31.7308 4 no
GO:0048584 positive regulation of response to stimulus 28.8462 4 no
GO:0051247 positive regulation of protein metabolic process 28.8462 6 no
GO:0044087 regulation of cellular component biogenesis 28.8462 4 no
GO:0031399 regulation of protein modification process 27.8846 6 no
GO:0120036 plasma membrane bounded cell projection organization 26.9231 5 no
GO:1902531 regulation of intracellular signal transduction 26.9231 5 no
GO:0051130 positive regulation of cellular component organization 26.9231 5 no
GO:0009892 negative regulation of metabolic process 26.9231 4 no
GO:0007010 cytoskeleton organization 25.9615 5 yes
GO:0019220 regulation of phosphate metabolic process 25.9615 6 no
GO:0051174 regulation of phosphorus metabolic process 25.9615 5 no
GO:0033043 regulation of organelle organization 25.9615 5 no
GO:0060341 regulation of cellular localization 25.9615 4 no
GO:0010605 negative regulation of macromolecule metabolic process 25.9615 5 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0032880 regulation of protein localization 24.0385 5 no
GO:0071702 organic substance transport 24.0385 4 no
GO:0009891 positive regulation of biosynthetic process 24.0385 5 no
GO:0001932 regulation of protein phosphorylation 23.0769 7 no
GO:0042325 regulation of phosphorylation 23.0769 7 no
GO:0071705 nitrogen compound transport 23.0769 4 no
GO:0031328 positive regulation of cellular biosynthetic process 23.0769 6 no
GO:0009967 positive regulation of signal transduction 22.1154 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 22.1154 6 no
GO:0022603 regulation of anatomical structure morphogenesis 21.1538 4 no
GO:0045595 regulation of cell differentiation 21.1538 4 no
GO:0051050 positive regulation of transport 21.1538 4 no
GO:0006355 regulation of DNA-templated transcription 21.1538 7 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.1538 5 no
GO:0051252 regulation of RNA metabolic process 21.1538 5 no
GO:2001141 regulation of RNA biosynthetic process 21.1538 6 no
GO:0071310 cellular response to organic substance 20.1923 4 no
GO:0034330 cell junction organization 18.2692 4 yes
GO:0034329 cell junction assembly 11.5385 5 yes
GO:0030705 cytoskeleton-dependent intracellular transport 7.6923 4 yes
GO:0099111 microtubule-based transport 7.6923 4 yes
GO:0010970 transport along microtubule 6.7308 4 yes
GO:0007229 integrin-mediated signaling pathway 4.8077 4 yes
GO:0008088 axo-dendritic transport 3.8462 5 yes
GO:0042060 wound healing 3.8462 4 yes
GO:0098930 axonal transport 3.8462 6 yes
GO:0007044 cell-substrate junction assembly 2.8846 6 yes
GO:0008090 retrograde axonal transport 2.8846 7 yes
GO:0031581 hemidesmosome assembly 2.8846 7 yes
GO:0150115 cell-substrate junction organization 2.8846 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DCTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ERBIN_HUMAN [view entry] [view interactions] Low throughput yes yes
COHA1_HUMAN [view interactions] Low throughput no no
ITB4_HUMAN [view entry] [view interactions] Low throughput yes yes
PERI_HUMAN [view entry] [view interactions] Low throughput yes no
NFL_HUMAN [view entry] [view interactions] Low throughput yes yes
NFH_HUMAN [view entry] [view interactions] Low throughput yes yes
MARE1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYST_HUMAN [view entry] [view interactions] Low throughput yes yes
RNPS1_HUMAN [view interactions] High throughput no yes
ALDR_HUMAN [view interactions] High throughput no no
PUF60_HUMAN [view interactions] High throughput no yes
CSKP_HUMAN [view entry] [view interactions] High throughput yes yes
HERC2_HUMAN [view interactions] High throughput no yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
BMI1_HUMAN [view interactions] High throughput no yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
CEP63_HUMAN [view interactions] High throughput no yes
APC_HUMAN [view entry] [view interactions] High throughput yes no
MK06_HUMAN [view interactions] High throughput no yes
NFYC_HUMAN [view interactions] High throughput no no
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
PE2R4_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
STK3_HUMAN [view interactions] High throughput no yes
RAB6A_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
CSAG2_HUMAN [view interactions] High throughput no no
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
ANKR1_HUMAN [view interactions] High throughput no no
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
C1T9A_HUMAN [view interactions] High throughput no no
CLIP4_HUMAN [view interactions] High throughput no yes
MYPC2_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
SNAPN_HUMAN [view interactions] High throughput no yes
TULP3_HUMAN [view interactions] High throughput no yes
FERM2_HUMAN [view interactions] High throughput no yes
PACN1_HUMAN [view entry] [view interactions] High throughput yes yes
CHP3_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
3BP5_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
MORC3_HUMAN [view interactions] High throughput no yes
RBM11_HUMAN [view interactions] High throughput no no
RSPH1_HUMAN [view interactions] High throughput no no
HUNK_HUMAN [view interactions] High throughput no yes
TTC3_HUMAN [view interactions] High throughput no yes
PCNT_HUMAN [view interactions] High throughput no yes
FTCD_HUMAN [view interactions] High throughput no no
ITSN1_HUMAN [view entry] [view interactions] High throughput yes yes
DSCAM_HUMAN [view interactions] High throughput no yes
NRIP1_HUMAN [view interactions] High throughput no yes
DSCR9_HUMAN [view interactions] High throughput no no
NFKB1_HUMAN [view interactions] High throughput no yes
PEBB_HUMAN [view interactions] High throughput no no
MOB1B_HUMAN [view interactions] High throughput no yes
MOB1A_HUMAN [view interactions] High throughput no yes
DRC5_HUMAN [view interactions] High throughput no no
TMM17_HUMAN [view interactions] High throughput no yes
BET1_HUMAN [view interactions] High throughput no no
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
TOM20_HUMAN [view entry] [view interactions] High throughput yes yes
TOM22_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
DYRK2_HUMAN [view interactions] High throughput no yes
EPHA1_HUMAN [view interactions] High throughput no yes
EPHA2_HUMAN [view interactions] High throughput no no
EPHA3_HUMAN [view interactions] High throughput no yes
FGFR2_HUMAN [view interactions] High throughput no yes
LTK_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
NTRK2_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRA_HUMAN [view interactions] High throughput no no
PGFRB_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view entry] [view interactions] High throughput yes no
STYK1_HUMAN [view interactions] High throughput no yes
SWAP1_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
AAKB2_HUMAN [view interactions] High throughput no yes
ECM29_HUMAN [view interactions] High throughput no no
4ET_HUMAN [view interactions] High throughput no yes
RT31_HUMAN [view interactions] High throughput no yes
TERF1_HUMAN [view interactions] High throughput no no
TERF2_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
MMS19_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
ADDA_HUMAN [view entry] [view interactions] High throughput yes yes
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
DREB_HUMAN [view entry] [view interactions] High throughput yes yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
LIMA1_HUMAN [view entry] [view interactions] High throughput yes no
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
MYO1C_HUMAN [view entry] [view interactions] High throughput yes yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
PPP6_HUMAN [view interactions] High throughput no yes
CE152_HUMAN [view interactions] High throughput no yes
GAN_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
WDTC1_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
TTC23_HUMAN [view interactions] High throughput no yes
TEDC2_HUMAN [view interactions] High throughput no no
SOCS6_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
K1C17_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
H4_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
NUPR1_HUMAN [view interactions] High throughput no no
NBR1_HUMAN [view interactions] High throughput no yes
UBQL1_HUMAN [view interactions] High throughput no yes
ID2_HUMAN [view interactions] High throughput no no
KCNE3_HUMAN [view interactions] High throughput no yes
TXLNA_HUMAN [view interactions] High throughput no yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
SPN90_HUMAN [view entry] [view interactions] High throughput yes no
CEA16_HUMAN [view interactions] High throughput no no
COQ4_HUMAN [view interactions] High throughput no yes
ACHA_HUMAN [view entry] [view interactions] High throughput yes no
NGN3_HUMAN [view interactions] High throughput no no
ISL2_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
FGD5_HUMAN [view interactions] High throughput no yes
RB40B_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOQ_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND1_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOU_HUMAN [view interactions] High throughput no no
BAP1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
CFAH_HUMAN [view interactions] High throughput no no
TBK1_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
UBP7_HUMAN [view interactions] High throughput no yes
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
CLMN_HUMAN [view entry] [view interactions] High throughput yes no
DOCK4_HUMAN [view entry] [view interactions] High throughput yes no
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
MICA2_HUMAN [view interactions] High throughput no yes
KLHL1_HUMAN [view interactions] High throughput no no
CAST2_HUMAN [view interactions] High throughput no no
GLRX3_HUMAN [view interactions] High throughput no yes
IF2G_HUMAN [view interactions] High throughput no yes
PDXD1_HUMAN [view interactions] High throughput no no
PGTA_HUMAN [view interactions] High throughput no yes
UBA5_HUMAN [view interactions] High throughput no yes
TBC23_HUMAN [view interactions] High throughput no yes
UGGG1_HUMAN [view interactions] High throughput no yes
ANFY1_HUMAN [view entry] [view interactions] High throughput yes yes
DYLT1_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
ACTC_HUMAN [view interactions] High throughput no no
RHDF2_HUMAN [view interactions] High throughput no yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
MIRO2_HUMAN [view entry] [view interactions] High throughput yes yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
CXAR_HUMAN [view interactions] High throughput no yes
DEN6A_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
GOGA1_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
LAMP2_HUMAN [view interactions] High throughput no yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
LMAN1_HUMAN [view entry] [view interactions] High throughput yes yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
AFAD_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
PARD3_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
STX6_HUMAN [view interactions] High throughput no yes
CELR3_HUMAN [view entry] [view interactions] High throughput yes no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
K1549_HUMAN [view entry] [view interactions] High throughput yes yes
SYNE3_HUMAN [view interactions] High throughput no no
VINC_HUMAN [view entry] [view interactions] High throughput yes no
ZFPL1_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
KPCD2_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD9_HUMAN [view interactions] High throughput no yes
ATG9A_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
NUP43_HUMAN [view interactions] High throughput no yes
EXOC1_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
AR13B_HUMAN [view interactions] High throughput no yes
MIPT3_HUMAN [view interactions] High throughput no yes
KDM1A_HUMAN [view interactions] High throughput no yes
MTR1B_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
S10A9_HUMAN [view entry] [view interactions] High throughput yes no
PF21A_HUMAN [view interactions] High throughput no yes
RCOR1_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
GSK3A_HUMAN [view interactions] High throughput no yes
CALL3_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
TCPR2_HUMAN [view interactions] High throughput no yes
RAB18_HUMAN [view entry] [view interactions] High throughput yes yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
RFA1_HUMAN [view interactions] High throughput no yes
MAGA1_HUMAN [view interactions] High throughput no no
RFA2_HUMAN [view interactions] High throughput no yes
CSN7B_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
RFA4_HUMAN [view interactions] High throughput no yes
KI67_HUMAN [view interactions] High throughput no no
MUC18_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
BRCA1_HUMAN [view interactions] High throughput no yes
LA_HUMAN [view interactions] High throughput no yes
RL1D1_HUMAN [view interactions] High throughput no yes
AT1A2_HUMAN [view entry] [view interactions] High throughput yes yes
CSTF3_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
SCRB2_HUMAN [view interactions] High throughput no yes
VMP1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
VSX1_HUMAN [view interactions] High throughput no no