ACSL3_HUMAN
Evidence for PS localization
Functions
Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed). Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (PubMed). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ACSL3_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 48.6842 | 4 | yes |
| GO:0000166 | nucleotide binding | 47.3684 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 47.3684 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 47.3684 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 47.3684 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 31.5789 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 31.5789 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 31.5789 | 6 | no |
| GO:0043169 | cation binding | 26.3158 | 4 | no |
| GO:0046872 | metal ion binding | 26.3158 | 5 | no |
| GO:0003924 | GTPase activity | 25.0000 | 7 | no |
| GO:0005525 | GTP binding | 25.0000 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 25.0000 | 6 | no |
| GO:0032561 | guanyl ribonucleotide binding | 25.0000 | 5 | no |
| GO:0005524 | ATP binding | 22.3684 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.3684 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.3684 | 5 | yes |
| GO:0019900 | kinase binding | 21.0526 | 4 | yes |
| GO:0019901 | protein kinase binding | 21.0526 | 5 | yes |
| GO:0016405 | CoA-ligase activity | 2.6316 | 4 | yes |
| GO:0016878 | acid-thiol ligase activity | 2.6316 | 4 | yes |
| GO:0047676 | arachidonate-CoA ligase activity | 2.6316 | 4 | yes |
| GO:0090433 | palmitoyl-CoA ligase activity | 2.6316 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACSL3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.1579 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 46.0526 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.7368 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.4211 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 43.4211 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 43.4211 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 42.1053 | 5 | yes |
| GO:0010468 | regulation of gene expression | 39.4737 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 39.4737 | 5 | no |
| GO:0008104 | protein localization | 39.4737 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 38.1579 | 4 | yes |
| GO:0006996 | organelle organization | 36.8421 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.8421 | 4 | no |
| GO:0051049 | regulation of transport | 35.5263 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 35.5263 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 35.5263 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.5263 | 4 | yes |
| GO:0071702 | organic substance transport | 34.2105 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 34.2105 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.2105 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.8947 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.8947 | 5 | yes |
| GO:0032880 | regulation of protein localization | 31.5789 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 30.2632 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 28.9474 | 4 | no |
| GO:0071705 | nitrogen compound transport | 28.9474 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.6316 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.6316 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 27.6316 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.6316 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.3158 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.3158 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.3158 | 5 | no |
| GO:0033043 | regulation of organelle organization | 26.3158 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 26.3158 | 5 | yes |
| GO:0022607 | cellular component assembly | 26.3158 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.0000 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 23.6842 | 5 | yes |
| GO:0030334 | regulation of cell migration | 23.6842 | 5 | no |
| GO:0031399 | regulation of protein modification process | 23.6842 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.6842 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 23.6842 | 5 | no |
| GO:2000145 | regulation of cell motility | 23.6842 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.6842 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 23.6842 | 6 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 22.3684 | 5 | no |
| GO:0071310 | cellular response to organic substance | 22.3684 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.3684 | 5 | no |
| GO:0015031 | protein transport | 22.3684 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.3684 | 4 | no |
| GO:0061024 | membrane organization | 22.3684 | 4 | no |
| GO:0070201 | regulation of establishment of protein localization | 21.0526 | 6 | yes |
| GO:1903829 | positive regulation of protein localization | 21.0526 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 21.0526 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.0526 | 6 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.0526 | 6 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.0526 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.0526 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.0526 | 5 | no |
| GO:0141124 | intracellular signaling cassette | 21.0526 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.0526 | 6 | no |
| GO:0043933 | protein-containing complex organization | 19.7368 | 4 | yes |
| GO:0051050 | positive regulation of transport | 19.7368 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 19.7368 | 4 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 18.4211 | 7 | yes |
| GO:0051046 | regulation of secretion | 18.4211 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 18.4211 | 6 | yes |
| GO:0098657 | import into cell | 17.1053 | 4 | yes |
| GO:0051223 | regulation of protein transport | 14.4737 | 5 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 14.4737 | 6 | yes |
| GO:1905475 | regulation of protein localization to membrane | 13.1579 | 6 | yes |
| GO:0051047 | positive regulation of secretion | 11.8421 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 11.8421 | 5 | yes |
| GO:0051222 | positive regulation of protein transport | 10.5263 | 5 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 10.5263 | 6 | yes |
| GO:1905477 | positive regulation of protein localization to membrane | 10.5263 | 6 | yes |
| GO:1903076 | regulation of protein localization to plasma membrane | 7.8947 | 7 | yes |
| GO:1904377 | positive regulation of protein localization to cell periphery | 7.8947 | 6 | yes |
| GO:0043436 | oxoacid metabolic process | 6.5789 | 4 | yes |
| GO:0072521 | purine-containing compound metabolic process | 6.5789 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 6.5789 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 6.5789 | 4 | yes |
| GO:1903078 | positive regulation of protein localization to plasma membrane | 6.5789 | 7 | yes |
| GO:0006163 | purine nucleotide metabolic process | 6.5789 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 6.5789 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 6.5789 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 6.5789 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 6.5789 | 5 | yes |
| GO:0019216 | regulation of lipid metabolic process | 6.5789 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 6.5789 | 4 | yes |
| GO:0019752 | carboxylic acid metabolic process | 6.5789 | 5 | yes |
| GO:0044272 | sulfur compound biosynthetic process | 5.2632 | 4 | yes |
| GO:0090407 | organophosphate biosynthetic process | 5.2632 | 4 | yes |
| GO:0006631 | fatty acid metabolic process | 5.2632 | 4 | yes |
| GO:0006869 | lipid transport | 5.2632 | 5 | yes |
| GO:0008610 | lipid biosynthetic process | 5.2632 | 4 | yes |
| GO:0030182 | neuron differentiation | 5.2632 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 5.2632 | 6 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 5.2632 | 4 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 3.9474 | 5 | yes |
| GO:0046890 | regulation of lipid biosynthetic process | 3.9474 | 5 | yes |
| GO:0046942 | carboxylic acid transport | 3.9474 | 6 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 3.9474 | 5 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 3.9474 | 4 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 3.9474 | 5 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 3.9474 | 6 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 3.9474 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 3.9474 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 3.9474 | 6 | yes |
| GO:0015711 | organic anion transport | 3.9474 | 5 | yes |
| GO:0015849 | organic acid transport | 3.9474 | 5 | yes |
| GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process | 2.6316 | 6 | yes |
| GO:0035384 | thioester biosynthetic process | 2.6316 | 4 | yes |
| GO:0045834 | positive regulation of lipid metabolic process | 2.6316 | 5 | yes |
| GO:0046889 | positive regulation of lipid biosynthetic process | 2.6316 | 6 | yes |
| GO:0046949 | fatty-acyl-CoA biosynthetic process | 2.6316 | 5 | yes |
| GO:0071616 | acyl-CoA biosynthetic process | 2.6316 | 4 | yes |
| GO:1901568 | fatty acid derivative metabolic process | 2.6316 | 4 | yes |
| GO:1901570 | fatty acid derivative biosynthetic process | 2.6316 | 5 | yes |
| GO:0001676 | long-chain fatty acid metabolic process | 2.6316 | 5 | yes |
| GO:0033865 | nucleoside bisphosphate metabolic process | 2.6316 | 5 | yes |
| GO:0033866 | nucleoside bisphosphate biosynthetic process | 2.6316 | 6 | yes |
| GO:0033875 | ribonucleoside bisphosphate metabolic process | 2.6316 | 6 | yes |
| GO:0034030 | ribonucleoside bisphosphate biosynthetic process | 2.6316 | 7 | yes |
| GO:0034032 | purine nucleoside bisphosphate metabolic process | 2.6316 | 5 | yes |
| GO:0034033 | purine nucleoside bisphosphate biosynthetic process | 2.6316 | 6 | yes |
| GO:0035336 | long-chain fatty-acyl-CoA metabolic process | 2.6316 | 5 | yes |
| GO:0035337 | fatty-acyl-CoA metabolic process | 2.6316 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| STX17_HUMAN | [view interactions] | Low throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| RASF1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF11_HUMAN | [view interactions] | High throughput | no | yes |
| CHK1_HUMAN | [view interactions] | High throughput | no | no |
| ACSL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIGD6_HUMAN | [view interactions] | High throughput | no | no |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| KI20B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAT2_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| MK07_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSPD2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| CO040_HUMAN | [view interactions] | High throughput | no | yes |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| DOC11_HUMAN | [view interactions] | High throughput | no | yes |
| TTBK1_HUMAN | [view interactions] | High throughput | no | yes |
| PPE1_HUMAN | [view interactions] | High throughput | no | no |
| NOD2_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| HIPK4_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| IF140_HUMAN | [view interactions] | High throughput | no | yes |
| WDR19_HUMAN | [view interactions] | High throughput | no | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| LBN_HUMAN | [view interactions] | High throughput | no | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLRKT_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| MK04_HUMAN | [view interactions] | High throughput | no | no |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| FGF11_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| TM41B_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| SPTC1_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| PAEP_HUMAN | [view interactions] | High throughput | no | no |
| HAVR2_HUMAN | [view interactions] | High throughput | no | no |
| IDD_HUMAN | [view interactions] | High throughput | no | no |
| EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRAD1_HUMAN | [view interactions] | High throughput | no | no |
| PBIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARMC5_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| ENTP2_HUMAN | [view interactions] | High throughput | no | yes |
| ADIPO_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| PTH2_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC16_HUMAN | [view interactions] | High throughput | no | no |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| CP2C9_HUMAN | [view interactions] | High throughput | no | no |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI2_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMT1A_HUMAN | [view interactions] | High throughput | no | no |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIAO1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| TEX2_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R2_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |