ACSL4_HUMAN
Evidence for PS localization
Functions
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed, PubMed, PubMed). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs . Modulates prostaglandin E2 secretion (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 570 | Arg | Ser | Intellectualdevelopmentaldisorder,X-linked63(XLID63) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ACSL4_HUMAN |
|---|---|---|---|---|
| GO:0035639 | purine ribonucleoside triphosphate binding | 36.1111 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 36.1111 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 36.1111 | 4 | yes |
| GO:0019900 | kinase binding | 33.3333 | 4 | no |
| GO:0019901 | protein kinase binding | 30.5556 | 5 | no |
| GO:0046872 | metal ion binding | 22.2222 | 4 | no |
| GO:0003924 | GTPase activity | 22.2222 | 7 | no |
| GO:0005525 | GTP binding | 22.2222 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 22.2222 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 22.2222 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 22.2222 | 6 | no |
| GO:0019001 | guanyl nucleotide binding | 22.2222 | 5 | no |
| GO:0032561 | guanyl ribonucleotide binding | 22.2222 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 13.8889 | 5 | yes |
| GO:0005524 | ATP binding | 13.8889 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 13.8889 | 5 | yes |
| GO:0047676 | arachidonate-CoA ligase activity | 5.5556 | 4 | yes |
| GO:0090433 | palmitoyl-CoA ligase activity | 5.5556 | 4 | yes |
| GO:0016405 | CoA-ligase activity | 5.5556 | 4 | yes |
| GO:0016878 | acid-thiol ligase activity | 5.5556 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACSL4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 61.1111 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 58.3333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 58.3333 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 55.5556 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.7778 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 52.7778 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 52.7778 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 52.7778 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 50.0000 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 47.2222 | 5 | no |
| GO:0010941 | regulation of cell death | 44.4444 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 44.4444 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 41.6667 | 6 | no |
| GO:0009966 | regulation of signal transduction | 41.6667 | 4 | no |
| GO:0033043 | regulation of organelle organization | 41.6667 | 5 | no |
| GO:0051049 | regulation of transport | 38.8889 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 38.8889 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 38.8889 | 5 | no |
| GO:0022607 | cellular component assembly | 38.8889 | 4 | no |
| GO:0071310 | cellular response to organic substance | 36.1111 | 4 | no |
| GO:0006996 | organelle organization | 36.1111 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.1111 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 36.1111 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 33.3333 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 33.3333 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 33.3333 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 33.3333 | 5 | no |
| GO:0071702 | organic substance transport | 33.3333 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 33.3333 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
| GO:0008104 | protein localization | 30.5556 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 30.5556 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 30.5556 | 7 | no |
| GO:0043085 | positive regulation of catalytic activity | 30.5556 | 4 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 30.5556 | 7 | no |
| GO:0060548 | negative regulation of cell death | 30.5556 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.5556 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 30.5556 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.5556 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 27.7778 | 7 | no |
| GO:0031399 | regulation of protein modification process | 27.7778 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 27.7778 | 7 | no |
| GO:0042327 | positive regulation of phosphorylation | 27.7778 | 8 | no |
| GO:0051338 | regulation of transferase activity | 27.7778 | 4 | no |
| GO:1901214 | regulation of neuron death | 27.7778 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 27.7778 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.7778 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.7778 | 5 | no |
| GO:0009894 | regulation of catabolic process | 27.7778 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.7778 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.7778 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 27.7778 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.7778 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 27.7778 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 27.7778 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 27.7778 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.7778 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.0000 | 4 | yes |
| GO:0051050 | positive regulation of transport | 25.0000 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 25.0000 | 8 | no |
| GO:0016192 | vesicle-mediated transport | 25.0000 | 4 | no |
| GO:0043523 | regulation of neuron apoptotic process | 25.0000 | 6 | no |
| GO:0043549 | regulation of kinase activity | 25.0000 | 5 | no |
| GO:0051347 | positive regulation of transferase activity | 25.0000 | 5 | no |
| GO:0071705 | nitrogen compound transport | 25.0000 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.0000 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 25.0000 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 25.0000 | 4 | no |
| GO:0043408 | regulation of MAPK cascade | 25.0000 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 25.0000 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 25.0000 | 6 | no |
| GO:0032880 | regulation of protein localization | 22.2222 | 5 | yes |
| GO:0051223 | regulation of protein transport | 22.2222 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 22.2222 | 4 | yes |
| GO:0070201 | regulation of establishment of protein localization | 22.2222 | 6 | yes |
| GO:0006915 | apoptotic process | 22.2222 | 4 | no |
| GO:0014070 | response to organic cyclic compound | 22.2222 | 4 | no |
| GO:0015031 | protein transport | 22.2222 | 4 | no |
| GO:0033674 | positive regulation of kinase activity | 22.2222 | 6 | no |
| GO:0036211 | protein modification process | 22.2222 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 22.2222 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.2222 | 6 | no |
| GO:0043412 | macromolecule modification | 22.2222 | 4 | no |
| GO:1901215 | negative regulation of neuron death | 22.2222 | 6 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 22.2222 | 7 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.2222 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 22.2222 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 22.2222 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.2222 | 4 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 22.2222 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.2222 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.2222 | 4 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 22.2222 | 6 | no |
| GO:0010638 | positive regulation of organelle organization | 22.2222 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 22.2222 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 22.2222 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 22.2222 | 4 | no |
| GO:0051726 | regulation of cell cycle | 22.2222 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.2222 | 6 | no |
| GO:0001558 | regulation of cell growth | 19.4444 | 4 | yes |
| GO:0043269 | regulation of ion transport | 16.6667 | 5 | yes |
| GO:0051046 | regulation of secretion | 16.6667 | 5 | yes |
| GO:1903829 | positive regulation of protein localization | 16.6667 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 13.8889 | 5 | yes |
| GO:0030307 | positive regulation of cell growth | 13.8889 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 13.8889 | 4 | yes |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 13.8889 | 4 | yes |
| GO:0045927 | positive regulation of growth | 13.8889 | 4 | yes |
| GO:0051222 | positive regulation of protein transport | 13.8889 | 5 | yes |
| GO:1903530 | regulation of secretion by cell | 13.8889 | 4 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 13.8889 | 6 | yes |
| GO:0006631 | fatty acid metabolic process | 11.1111 | 4 | yes |
| GO:0008610 | lipid biosynthetic process | 11.1111 | 4 | yes |
| GO:0018130 | heterocycle biosynthetic process | 11.1111 | 4 | yes |
| GO:0019438 | aromatic compound biosynthetic process | 11.1111 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 11.1111 | 6 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 11.1111 | 4 | yes |
| GO:0051047 | positive regulation of secretion | 11.1111 | 5 | yes |
| GO:0051051 | negative regulation of transport | 11.1111 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 11.1111 | 4 | yes |
| GO:0001676 | long-chain fatty acid metabolic process | 8.3333 | 5 | yes |
| GO:0002791 | regulation of peptide secretion | 8.3333 | 6 | yes |
| GO:0006163 | purine nucleotide metabolic process | 8.3333 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 8.3333 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 8.3333 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 8.3333 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 8.3333 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 8.3333 | 4 | yes |
| GO:0043603 | cellular amide metabolic process | 8.3333 | 4 | yes |
| GO:0043604 | amide biosynthetic process | 8.3333 | 5 | yes |
| GO:0044272 | sulfur compound biosynthetic process | 8.3333 | 4 | yes |
| GO:0046883 | regulation of hormone secretion | 8.3333 | 4 | yes |
| GO:0050708 | regulation of protein secretion | 8.3333 | 5 | yes |
| GO:0050796 | regulation of insulin secretion | 8.3333 | 6 | yes |
| GO:0051048 | negative regulation of secretion | 8.3333 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 8.3333 | 4 | yes |
| GO:0090087 | regulation of peptide transport | 8.3333 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 8.3333 | 5 | yes |
| GO:0090407 | organophosphate biosynthetic process | 8.3333 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 8.3333 | 4 | yes |
| GO:1903531 | negative regulation of secretion by cell | 8.3333 | 5 | yes |
| GO:1903532 | positive regulation of secretion by cell | 8.3333 | 5 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 5.5556 | 6 | yes |
| GO:0006637 | acyl-CoA metabolic process | 5.5556 | 4 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 5.5556 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 5.5556 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 5.5556 | 6 | yes |
| GO:0030182 | neuron differentiation | 5.5556 | 4 | yes |
| GO:0032368 | regulation of lipid transport | 5.5556 | 5 | yes |
| GO:0033865 | nucleoside bisphosphate metabolic process | 5.5556 | 5 | yes |
| GO:0033866 | nucleoside bisphosphate biosynthetic process | 5.5556 | 6 | yes |
| GO:0033875 | ribonucleoside bisphosphate metabolic process | 5.5556 | 6 | yes |
| GO:0034030 | ribonucleoside bisphosphate biosynthetic process | 5.5556 | 7 | yes |
| GO:0034032 | purine nucleoside bisphosphate metabolic process | 5.5556 | 5 | yes |
| GO:0034033 | purine nucleoside bisphosphate biosynthetic process | 5.5556 | 6 | yes |
| GO:0035336 | long-chain fatty-acyl-CoA metabolic process | 5.5556 | 6 | yes |
| GO:0035337 | fatty-acyl-CoA metabolic process | 5.5556 | 5 | yes |
| GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process | 5.5556 | 7 | yes |
| GO:0035384 | thioester biosynthetic process | 5.5556 | 4 | yes |
| GO:0043271 | negative regulation of ion transport | 5.5556 | 5 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 5.5556 | 5 | yes |
| GO:0046949 | fatty-acyl-CoA biosynthetic process | 5.5556 | 6 | yes |
| GO:0071616 | acyl-CoA biosynthetic process | 5.5556 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 5.5556 | 5 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 5.5556 | 4 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 5.5556 | 5 | yes |
| GO:1901568 | fatty acid derivative metabolic process | 5.5556 | 4 | yes |
| GO:1901570 | fatty acid derivative biosynthetic process | 5.5556 | 5 | yes |
| GO:1905952 | regulation of lipid localization | 5.5556 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| STING_HUMAN | [view interactions] | Low throughput | no | yes |
| HTAI2_HUMAN | [view interactions] | Low throughput | no | yes |
| TNAP3_HUMAN | [view interactions] | Low throughput | no | yes |
| UVRAG_HUMAN | [view interactions] | High throughput | no | yes |
| ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| TF3B_HUMAN | [view interactions] | High throughput | no | yes |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| RT15_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH2_HUMAN | [view interactions] | High throughput | no | yes |
| CHC10_HUMAN | [view interactions] | High throughput | no | yes |
| SPT20_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2B1H_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| DSE_HUMAN | [view interactions] | High throughput | no | yes |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| FOXA3_HUMAN | [view interactions] | High throughput | no | yes |
| FOXL2_HUMAN | [view interactions] | High throughput | no | no |
| FOXQ1_HUMAN | [view interactions] | High throughput | no | no |
| FOXI2_HUMAN | [view interactions] | High throughput | no | no |
| FOXJ1_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MIC10_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| EID3_HUMAN | [view interactions] | High throughput | no | no |
| GNAT2_HUMAN | [view interactions] | High throughput | no | no |
| TB22A_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCG1_HUMAN | [view interactions] | High throughput | no | yes |
| TJAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP2_HUMAN | [view interactions] | High throughput | no | no |
| NEP_HUMAN | [view interactions] | High throughput | no | no |
| S6A15_HUMAN | [view interactions] | High throughput | no | yes |
| S15A1_HUMAN | [view interactions] | High throughput | no | no |
| S39AC_HUMAN | [view interactions] | High throughput | no | no |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| RN185_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| CRCM1_HUMAN | [view interactions] | High throughput | no | yes |
| OPRX_HUMAN | [view interactions] | High throughput | no | no |
| NAGAB_HUMAN | [view interactions] | High throughput | no | yes |
| TCPQM_HUMAN | [view interactions] | High throughput | no | no |
| TTYH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S22A2_HUMAN | [view interactions] | High throughput | no | no |
| GPR12_HUMAN | [view interactions] | High throughput | no | no |
| COPT1_HUMAN | [view interactions] | High throughput | no | no |
| TNFL8_HUMAN | [view interactions] | High throughput | no | no |
| EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DQA1_HUMAN | [view interactions] | High throughput | no | yes |
| GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASGR2_HUMAN | [view interactions] | High throughput | no | no |
| RSP14_HUMAN | [view interactions] | High throughput | no | no |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| LCN6_HUMAN | [view interactions] | High throughput | no | no |
| T150A_HUMAN | [view interactions] | High throughput | no | yes |
| BRNP2_HUMAN | [view interactions] | High throughput | no | no |
| ACTT2_HUMAN | [view interactions] | High throughput | no | no |
| S22A9_HUMAN | [view interactions] | High throughput | no | no |
| NPRL3_HUMAN | [view interactions] | High throughput | no | yes |
| DHI1_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| KCNK1_HUMAN | [view interactions] | High throughput | no | yes |
| TGT_HUMAN | [view interactions] | High throughput | no | no |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| DMB_HUMAN | [view interactions] | High throughput | no | no |
| NUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| NKG2A_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANTR1_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMT1_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELOV6_HUMAN | [view interactions] | Computational | no | yes |
| ELOV1_HUMAN | [view interactions] | Computational | no | yes |
| AMMR1_HUMAN | [view interactions] | Computational | no | no |
| ACOX1_HUMAN | [view interactions] | Computational | no | yes |
| CPT1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FAS_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ACADL_HUMAN | [view interactions] | Computational | no | no |
| CO4A5_HUMAN | [view interactions] | Computational | no | no |
| FADS2_HUMAN | [view interactions] | Computational | no | yes |
| ACOX2_HUMAN | [view interactions] | Computational | no | yes |