HXK1_HUMAN
Evidence for PS localization
Functions
Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate, respectively) (PubMed, PubMed, PubMed). Does not phosphorylate N-acetyl-D-glucosamine (PubMed). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate . Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial peptidoglycan (PubMed). When released in the cytosol, N-acetyl-D-glucosamine component of bacterial peptidoglycan inhibits the hexokinase activity of HK1 and causes its dissociation from mitochondrial outer membrane, thereby activating the NLRP3 inflammasome (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in HXK1_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 36.1702 | 4 | yes |
| GO:0043168 | anion binding | 36.1702 | 4 | yes |
| GO:0043169 | cation binding | 35.1064 | 4 | no |
| GO:0017076 | purine nucleotide binding | 32.9787 | 5 | yes |
| GO:0046872 | metal ion binding | 32.9787 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 29.7872 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.7234 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 20.2128 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 20.2128 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 20.2128 | 6 | no |
| GO:0030554 | adenyl nucleotide binding | 15.9574 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 12.7660 | 5 | yes |
| GO:0005524 | ATP binding | 11.7021 | 5 | yes |
| GO:0016301 | kinase activity | 8.5106 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 8.5106 | 4 | yes |
| GO:0004340 | glucokinase activity | 2.1277 | 6 | yes |
| GO:0004396 | hexokinase activity | 2.1277 | 5 | yes |
| GO:0005536 | glucose binding | 2.1277 | 4 | yes |
| GO:0008865 | fructokinase activity | 2.1277 | 6 | yes |
| GO:0019158 | mannokinase activity | 2.1277 | 6 | yes |
| GO:0019200 | carbohydrate kinase activity | 2.1277 | 5 | yes |
| GO:0042834 | peptidoglycan binding | 2.1277 | 4 | yes |
| GO:0047931 | glucosamine kinase activity | 2.1277 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HXK1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.2553 | 4 | yes |
| GO:0006996 | organelle organization | 46.8085 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 42.5532 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 39.3617 | 4 | yes |
| GO:0022607 | cellular component assembly | 38.2979 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 37.2340 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 37.2340 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 35.1064 | 4 | no |
| GO:0008104 | protein localization | 34.0426 | 4 | yes |
| GO:0010646 | regulation of cell communication | 34.0426 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 31.9149 | 4 | yes |
| GO:0071702 | organic substance transport | 30.8511 | 4 | no |
| GO:0009966 | regulation of signal transduction | 30.8511 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 29.7872 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 29.7872 | 5 | no |
| GO:0010468 | regulation of gene expression | 28.7234 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.7234 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 28.7234 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 28.7234 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.6596 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 27.6596 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.6596 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 25.5319 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 25.5319 | 4 | no |
| GO:0051049 | regulation of transport | 25.5319 | 4 | no |
| GO:0033043 | regulation of organelle organization | 24.4681 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 24.4681 | 4 | no |
| GO:0009894 | regulation of catabolic process | 24.4681 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.4681 | 4 | no |
| GO:0032880 | regulation of protein localization | 23.4043 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.4043 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.4043 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.4043 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.3404 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 22.3404 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.3404 | 4 | no |
| GO:0033365 | protein localization to organelle | 21.2766 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 21.2766 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.2766 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 20.2128 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 20.2128 | 5 | yes |
| GO:0015031 | protein transport | 20.2128 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.2128 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 19.1489 | 6 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 17.0213 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 15.9574 | 6 | yes |
| GO:0010628 | positive regulation of gene expression | 14.8936 | 7 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 13.8298 | 4 | yes |
| GO:0072594 | establishment of protein localization to organelle | 12.7660 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 11.7021 | 4 | yes |
| GO:0070585 | protein localization to mitochondrion | 11.7021 | 6 | yes |
| GO:0072521 | purine-containing compound metabolic process | 11.7021 | 4 | yes |
| GO:0006163 | purine nucleotide metabolic process | 10.6383 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 10.6383 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 10.6383 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 10.6383 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 10.6383 | 4 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 9.5745 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 9.5745 | 6 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 9.5745 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 9.5745 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 9.5745 | 7 | yes |
| GO:0009259 | ribonucleotide metabolic process | 9.5745 | 5 | yes |
| GO:0016310 | phosphorylation | 9.5745 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 9.5745 | 4 | yes |
| GO:0046034 | ATP metabolic process | 9.5745 | 7 | yes |
| GO:0072655 | establishment of protein localization to mitochondrion | 9.5745 | 5 | yes |
| GO:0001817 | regulation of cytokine production | 7.4468 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 7.4468 | 6 | yes |
| GO:0140546 | defense response to symbiont | 7.4468 | 4 | yes |
| GO:0001819 | positive regulation of cytokine production | 6.3830 | 5 | yes |
| GO:0002697 | regulation of immune effector process | 6.3830 | 4 | yes |
| GO:0006006 | glucose metabolic process | 6.3830 | 5 | yes |
| GO:0019318 | hexose metabolic process | 6.3830 | 4 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 6.3830 | 4 | yes |
| GO:0002699 | positive regulation of immune effector process | 5.3191 | 5 | yes |
| GO:0019362 | pyridine nucleotide metabolic process | 5.3191 | 5 | yes |
| GO:0034655 | nucleobase-containing compound catabolic process | 5.3191 | 4 | yes |
| GO:0046496 | nicotinamide nucleotide metabolic process | 5.3191 | 6 | yes |
| GO:0072524 | pyridine-containing compound metabolic process | 5.3191 | 4 | yes |
| GO:0002700 | regulation of production of molecular mediator of immune response | 4.2553 | 5 | yes |
| GO:0002702 | positive regulation of production of molecular mediator of immune response | 4.2553 | 6 | yes |
| GO:0006090 | pyruvate metabolic process | 4.2553 | 7 | yes |
| GO:0006734 | NADH metabolic process | 4.2553 | 7 | yes |
| GO:0009166 | nucleotide catabolic process | 4.2553 | 6 | yes |
| GO:0019674 | NAD metabolic process | 4.2553 | 6 | yes |
| GO:0042593 | glucose homeostasis | 4.2553 | 4 | yes |
| GO:0046434 | organophosphate catabolic process | 4.2553 | 4 | yes |
| GO:1901292 | nucleoside phosphate catabolic process | 4.2553 | 5 | yes |
| GO:0001678 | intracellular glucose homeostasis | 3.1915 | 4 | yes |
| GO:0002718 | regulation of cytokine production involved in immune response | 3.1915 | 5 | yes |
| GO:0002720 | positive regulation of cytokine production involved in immune response | 3.1915 | 6 | yes |
| GO:0006007 | glucose catabolic process | 3.1915 | 6 | yes |
| GO:0006096 | glycolytic process | 3.1915 | 4 | yes |
| GO:0006195 | purine nucleotide catabolic process | 3.1915 | 6 | yes |
| GO:0006735 | NADH regeneration | 3.1915 | 8 | yes |
| GO:0006954 | inflammatory response | 3.1915 | 4 | yes |
| GO:0009132 | nucleoside diphosphate metabolic process | 3.1915 | 5 | yes |
| GO:0009134 | nucleoside diphosphate catabolic process | 3.1915 | 6 | yes |
| GO:0009135 | purine nucleoside diphosphate metabolic process | 3.1915 | 6 | yes |
| GO:0009137 | purine nucleoside diphosphate catabolic process | 3.1915 | 7 | yes |
| GO:0009154 | purine ribonucleotide catabolic process | 3.1915 | 6 | yes |
| GO:0009179 | purine ribonucleoside diphosphate metabolic process | 3.1915 | 7 | yes |
| GO:0009181 | purine ribonucleoside diphosphate catabolic process | 3.1915 | 8 | yes |
| GO:0009185 | ribonucleoside diphosphate metabolic process | 3.1915 | 6 | yes |
| GO:0009191 | ribonucleoside diphosphate catabolic process | 3.1915 | 7 | yes |
| GO:0009261 | ribonucleotide catabolic process | 3.1915 | 5 | yes |
| GO:0016052 | carbohydrate catabolic process | 3.1915 | 4 | yes |
| GO:0019320 | hexose catabolic process | 3.1915 | 5 | yes |
| GO:0019364 | pyridine nucleotide catabolic process | 3.1915 | 6 | yes |
| GO:0019677 | NAD catabolic process | 3.1915 | 7 | yes |
| GO:0032651 | regulation of interleukin-1 beta production | 3.1915 | 6 | yes |
| GO:0032652 | regulation of interleukin-1 production | 3.1915 | 5 | yes |
| GO:0032731 | positive regulation of interleukin-1 beta production | 3.1915 | 7 | yes |
| GO:0032732 | positive regulation of interleukin-1 production | 3.1915 | 6 | yes |
| GO:0046031 | ADP metabolic process | 3.1915 | 7 | yes |
| GO:0046032 | ADP catabolic process | 3.1915 | 7 | yes |
| GO:0046365 | monosaccharide catabolic process | 3.1915 | 4 | yes |
| GO:0061615 | glycolytic process through fructose-6-phosphate | 3.1915 | 5 | yes |
| GO:0061620 | glycolytic process through glucose-6-phosphate | 3.1915 | 6 | yes |
| GO:0061621 | canonical glycolysis | 3.1915 | 7 | yes |
| GO:0061718 | glucose catabolic process to pyruvate | 3.1915 | 7 | yes |
| GO:0072523 | purine-containing compound catabolic process | 3.1915 | 5 | yes |
| GO:0072526 | pyridine-containing compound catabolic process | 3.1915 | 5 | yes |
| GO:0072595 | maintenance of protein localization in organelle | 3.1915 | 4 | yes |
| GO:0072656 | maintenance of protein location in mitochondrion | 3.1915 | 5 | yes |
| GO:1901136 | carbohydrate derivative catabolic process | 3.1915 | 4 | yes |
| GO:0006002 | fructose 6-phosphate metabolic process | 2.1277 | 4 | yes |
| GO:0006013 | mannose metabolic process | 2.1277 | 5 | yes |
| GO:0046835 | carbohydrate phosphorylation | 2.1277 | 4 | yes |
| GO:0051156 | glucose 6-phosphate metabolic process | 2.1277 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RETR1_HUMAN | [view interactions] | Low throughput | no | no |
| ATF2_HUMAN | [view interactions] | Low throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HXK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PER2_HUMAN | [view interactions] | Low throughput | no | yes |
| RN146_HUMAN | [view interactions] | Low throughput | no | yes |
| P4HA2_HUMAN | [view interactions] | High throughput | no | no |
| ADPGK_HUMAN | [view interactions] | High throughput | no | no |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2513_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPH_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FACE1_HUMAN | [view interactions] | High throughput | no | yes |
| TMED7_HUMAN | [view interactions] | High throughput | no | yes |
| LUM_HUMAN | [view interactions] | High throughput | no | no |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYJ2B_HUMAN | [view interactions] | High throughput | no | no |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| S2512_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLRX2_HUMAN | [view interactions] | High throughput | no | yes |
| PYGL_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPD2B_HUMAN | [view interactions] | High throughput | no | no |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| PTH2_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| MARH5_HUMAN | [view interactions] | High throughput | no | no |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| ARL10_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| IFT27_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4G_HUMAN | [view interactions] | High throughput | no | no |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSF1_HUMAN | [view interactions] | High throughput | no | yes |
| DYH6_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| PSKH2_HUMAN | [view interactions] | High throughput | no | no |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| NEUL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCMH1_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX4_HUMAN | [view interactions] | High throughput | no | yes |
| MAX_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP1_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| AXA2L_HUMAN | [view interactions] | High throughput | no | no |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| GLO2_HUMAN | [view interactions] | High throughput | no | yes |
| LRC49_HUMAN | [view interactions] | High throughput | no | no |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| ZFP14_HUMAN | [view interactions] | High throughput | no | no |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLRKT_HUMAN | [view interactions] | High throughput | no | yes |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| HKDC1_HUMAN | [view interactions] | High throughput | no | no |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| ASPC1_HUMAN | [view interactions] | High throughput | no | yes |
| HXK3_HUMAN | [view interactions] | High throughput | no | no |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| HS12B_HUMAN | [view interactions] | High throughput | no | yes |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| AQ12B_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | High throughput | no | no |
| MTG16_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARLY_HUMAN | [view interactions] | High throughput | no | no |
| CAN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TF3C4_HUMAN | [view interactions] | High throughput | no | no |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| FKBP9_HUMAN | [view interactions] | High throughput | no | yes |
| HEXA_HUMAN | [view interactions] | High throughput | no | yes |
| HEXB_HUMAN | [view interactions] | High throughput | no | no |
| PDC10_HUMAN | [view interactions] | High throughput | no | yes |
| PLPHP_HUMAN | [view interactions] | High throughput | no | yes |
| SYRC_HUMAN | [view interactions] | High throughput | no | yes |
| SGTA_HUMAN | [view interactions] | High throughput | no | yes |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP6_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| PLAP_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TWF2_HUMAN | [view interactions] | High throughput | no | no |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN1_HUMAN | [view interactions] | High throughput | no | no |
| ASPDH_HUMAN | [view interactions] | High throughput | no | yes |
| HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
| ODBB_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PON2_HUMAN | [view interactions] | High throughput | no | yes |
| CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| LRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTYH3_HUMAN | [view interactions] | High throughput | no | yes |
| TPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P3H2_HUMAN | [view interactions] | High throughput | no | yes |
| BPIB3_HUMAN | [view interactions] | High throughput | no | no |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NNTM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATLA3_HUMAN | [view interactions] | High throughput | no | no |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| P3H1_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |