EXOC5_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC5_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 26.6667 | 4 | no |
| GO:0000166 | nucleotide binding | 24.4444 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.4444 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.2222 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0051020 | GTPase binding | 13.3333 | 4 | yes |
| GO:0031267 | small GTPase binding | 11.1111 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC5_HUMAN |
|---|---|---|---|---|
| GO:0071702 | organic substance transport | 55.5556 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 55.5556 | 4 | yes |
| GO:0008104 | protein localization | 51.1111 | 4 | yes |
| GO:0006996 | organelle organization | 48.8889 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 48.8889 | 4 | no |
| GO:0015031 | protein transport | 46.6667 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.6667 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 46.6667 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 46.6667 | 4 | no |
| GO:0051049 | regulation of transport | 44.4444 | 4 | no |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | yes |
| GO:0061024 | membrane organization | 40.0000 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 40.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 40.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.7778 | 4 | no |
| GO:0009966 | regulation of signal transduction | 37.7778 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 37.7778 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 35.5556 | 5 | no |
| GO:0046903 | secretion | 33.3333 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 33.3333 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 31.1111 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.1111 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 31.1111 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 28.8889 | 4 | no |
| GO:0048278 | vesicle docking | 26.6667 | 4 | yes |
| GO:0010468 | regulation of gene expression | 26.6667 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.6667 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.6667 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.6667 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.6667 | 4 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 26.6667 | 4 | no |
| GO:0031399 | regulation of protein modification process | 26.6667 | 6 | no |
| GO:0090148 | membrane fission | 24.4444 | 5 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 24.4444 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.4444 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.4444 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 24.4444 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 24.4444 | 5 | no |
| GO:0023057 | negative regulation of signaling | 24.4444 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.4444 | 4 | no |
| GO:0051046 | regulation of secretion | 24.4444 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 24.4444 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.4444 | 6 | no |
| GO:0000281 | mitotic cytokinesis | 22.2222 | 4 | yes |
| GO:0006892 | post-Golgi vesicle-mediated transport | 22.2222 | 4 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 22.2222 | 4 | yes |
| GO:0070925 | organelle assembly | 22.2222 | 5 | yes |
| GO:0099022 | vesicle tethering | 22.2222 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 22.2222 | 5 | no |
| GO:0010506 | regulation of autophagy | 22.2222 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 22.2222 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.2222 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.2222 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.2222 | 4 | no |
| GO:0006886 | intracellular protein transport | 22.2222 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.2222 | 4 | no |
| GO:0006893 | Golgi to plasma membrane transport | 20.0000 | 4 | yes |
| GO:0006915 | apoptotic process | 20.0000 | 4 | yes |
| GO:0030030 | cell projection organization | 20.0000 | 4 | yes |
| GO:0072657 | protein localization to membrane | 20.0000 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 17.7778 | 5 | yes |
| GO:0072659 | protein localization to plasma membrane | 15.5556 | 5 | yes |
| GO:1990778 | protein localization to cell periphery | 15.5556 | 5 | yes |
| GO:0030031 | cell projection assembly | 8.8889 | 5 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 8.8889 | 6 | yes |
| GO:0044782 | cilium organization | 6.6667 | 5 | yes |
| GO:0060271 | cilium assembly | 6.6667 | 6 | yes |
| GO:1904019 | epithelial cell apoptotic process | 6.6667 | 5 | yes |
| GO:0001736 | establishment of planar polarity | 4.4444 | 4 | yes |
| GO:1905515 | non-motile cilium assembly | 4.4444 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN609_HUMAN | [view interactions] | High throughput | no | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDRF1_HUMAN | [view interactions] | High throughput | no | no |
| TT23L_HUMAN | [view interactions] | High throughput | no | no |
| PPIP1_HUMAN | [view interactions] | High throughput | no | no |
| DAAF4_HUMAN | [view interactions] | High throughput | no | yes |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| FIBA_HUMAN | [view interactions] | High throughput | no | no |
| CBP_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| PNKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| OPRM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EDNRB_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SCHI1_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| GLPA_HUMAN | [view interactions] | High throughput | no | no |
| CC018_HUMAN | [view interactions] | High throughput | no | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| GLR_HUMAN | [view interactions] | High throughput | no | no |
| CML1_HUMAN | [view interactions] | High throughput | no | yes |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| GGA1_HUMAN | [view interactions] | High throughput | no | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KT222_HUMAN | [view interactions] | High throughput | no | no |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNPO2_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| NPY2R_HUMAN | [view interactions] | High throughput | no | no |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| CAH14_HUMAN | [view interactions] | High throughput | no | yes |
| ERP29_HUMAN | [view interactions] | High throughput | no | yes |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSN1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| CADH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICA69_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX10_HUMAN | [view interactions] | High throughput | no | yes |
| TBX21_HUMAN | [view interactions] | High throughput | no | no |
| ADCK1_HUMAN | [view interactions] | High throughput | no | no |
| ARP3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEUP1_HUMAN | [view interactions] | High throughput | no | no |
| OAS1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB4B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXN4A_HUMAN | [view interactions] | High throughput | no | no |
| PTK6_HUMAN | [view interactions] | High throughput | no | yes |
| BRM1L_HUMAN | [view interactions] | High throughput | no | no |
| C102B_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| TXLNB_HUMAN | [view interactions] | High throughput | no | no |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| MESH1_HUMAN | [view interactions] | High throughput | no | yes |
| SACA9_HUMAN | [view interactions] | High throughput | no | no |
| FRMD6_HUMAN | [view interactions] | High throughput | no | no |
| BARD1_HUMAN | [view interactions] | High throughput | no | yes |
| ASC_HUMAN | [view interactions] | High throughput | no | no |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFT57_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| CRBB1_HUMAN | [view interactions] | High throughput | no | no |
| THOC1_HUMAN | [view interactions] | High throughput | no | yes |
| CA216_HUMAN | [view interactions] | High throughput | no | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| CRYAB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |