EXOC2_HUMAN
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EXOC2_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 34.2105 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 34.2105 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 34.2105 | 4 | no |
GO:0003924 | GTPase activity | 23.6842 | 7 | no |
GO:0005525 | GTP binding | 23.6842 | 5 | no |
GO:0016462 | pyrophosphatase activity | 23.6842 | 5 | no |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.6842 | 4 | no |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.6842 | 6 | no |
GO:0019001 | guanyl nucleotide binding | 23.6842 | 5 | no |
GO:0032561 | guanyl ribonucleotide binding | 23.6842 | 5 | no |
GO:0031267 | small GTPase binding | 21.0526 | 5 | yes |
GO:0051020 | GTPase binding | 21.0526 | 4 | yes |
GO:0019900 | kinase binding | 13.1579 | 4 | yes |
GO:0019901 | protein kinase binding | 13.1579 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EXOC2_HUMAN |
---|---|---|---|---|
GO:0008104 | protein localization | 73.6842 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 65.7895 | 4 | yes |
GO:0071702 | organic substance transport | 65.7895 | 4 | yes |
GO:0071705 | nitrogen compound transport | 65.7895 | 4 | yes |
GO:0015031 | protein transport | 63.1579 | 4 | yes |
GO:0006996 | organelle organization | 50.0000 | 4 | no |
GO:0046903 | secretion | 47.3684 | 4 | yes |
GO:0006887 | exocytosis | 39.4737 | 4 | yes |
GO:0098876 | vesicle-mediated transport to the plasma membrane | 39.4737 | 4 | yes |
GO:0022607 | cellular component assembly | 39.4737 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 36.8421 | 4 | no |
GO:0048522 | positive regulation of cellular process | 36.8421 | 4 | no |
GO:0051128 | regulation of cellular component organization | 34.2105 | 4 | no |
GO:0030030 | cell projection organization | 31.5789 | 4 | no |
GO:0010646 | regulation of cell communication | 31.5789 | 4 | no |
GO:0051049 | regulation of transport | 31.5789 | 4 | no |
GO:0006892 | post-Golgi vesicle-mediated transport | 28.9474 | 6 | yes |
GO:0048193 | Golgi vesicle transport | 28.9474 | 5 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 28.9474 | 5 | no |
GO:0060255 | regulation of macromolecule metabolic process | 28.9474 | 4 | no |
GO:0048523 | negative regulation of cellular process | 28.9474 | 4 | no |
GO:0072657 | protein localization to membrane | 26.3158 | 4 | no |
GO:1990778 | protein localization to cell periphery | 26.3158 | 5 | no |
GO:0009966 | regulation of signal transduction | 26.3158 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 26.3158 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 26.3158 | 4 | no |
GO:0006886 | intracellular protein transport | 26.3158 | 4 | no |
GO:0007010 | cytoskeleton organization | 26.3158 | 5 | no |
GO:0033365 | protein localization to organelle | 23.6842 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 23.6842 | 4 | no |
GO:0010468 | regulation of gene expression | 23.6842 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 23.6842 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 23.6842 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 23.6842 | 5 | no |
GO:0060627 | regulation of vesicle-mediated transport | 23.6842 | 4 | no |
GO:0006893 | Golgi to plasma membrane transport | 21.0526 | 5 | yes |
GO:0009894 | regulation of catabolic process | 21.0526 | 4 | no |
GO:0031329 | regulation of cellular catabolic process | 21.0526 | 5 | no |
GO:0032880 | regulation of protein localization | 21.0526 | 5 | no |
GO:0051094 | positive regulation of developmental process | 21.0526 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 21.0526 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 21.0526 | 6 | no |
GO:0060341 | regulation of cellular localization | 21.0526 | 4 | no |
GO:0010243 | response to organonitrogen compound | 21.0526 | 4 | no |
GO:0051046 | regulation of secretion | 21.0526 | 5 | no |
GO:1903530 | regulation of secretion by cell | 21.0526 | 4 | no |
GO:0052372 | modulation by symbiont of entry into host | 7.8947 | 4 | yes |
GO:2000535 | regulation of entry of bacterium into host cell | 5.2632 | 5 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in EXOC2_HUMAN |
---|---|---|---|---|
DOID:1289 | neurodegenerative disease | 5.2632 | 4 | no |
DOID:331 | central nervous system disease | 5.2632 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
RALB_HUMAN | [view interactions] | Low throughput | no | no |
EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VPS53_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EXOC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
EXOC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRGEF_HUMAN | [view interactions] | Low throughput | no | yes |
RALA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P2RY6_HUMAN | [view interactions] | High throughput | no | no |
TN13B_HUMAN | [view interactions] | High throughput | no | no |
AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNW1_HUMAN | [view interactions] | High throughput | no | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
ESX1_HUMAN | [view interactions] | High throughput | no | no |
CDN2A_HUMAN | [view interactions] | High throughput | no | yes |
EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP33_HUMAN | [view interactions] | High throughput | no | yes |
PK3C3_HUMAN | [view interactions] | High throughput | no | yes |
ULK1_HUMAN | [view interactions] | High throughput | no | no |
GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LPAR6_HUMAN | [view interactions] | High throughput | no | no |
PE2R3_HUMAN | [view interactions] | High throughput | no | no |
SCN2B_HUMAN | [view interactions] | High throughput | no | no |
SCAR3_HUMAN | [view interactions] | High throughput | no | yes |
5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
LNX2_HUMAN | [view interactions] | High throughput | no | yes |
EDNRB_HUMAN | [view interactions] | High throughput | no | no |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
WDR76_HUMAN | [view interactions] | High throughput | no | no |
H4_HUMAN | [view interactions] | High throughput | no | yes |
H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
CTDP1_HUMAN | [view interactions] | High throughput | no | yes |
HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
GLPA_HUMAN | [view interactions] | High throughput | no | no |
NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GP182_HUMAN | [view interactions] | High throughput | no | no |
CD6_HUMAN | [view interactions] | High throughput | no | no |
KI2L4_HUMAN | [view interactions] | High throughput | no | no |
CD70_HUMAN | [view interactions] | High throughput | no | no |
EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
GPR17_HUMAN | [view interactions] | High throughput | no | no |
CXCR4_HUMAN | [view interactions] | High throughput | no | no |
FXYD3_HUMAN | [view interactions] | High throughput | no | yes |
P2Y10_HUMAN | [view interactions] | High throughput | no | no |
VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
V2R_HUMAN | [view interactions] | High throughput | no | no |
FPR1_HUMAN | [view interactions] | High throughput | no | no |
GPR45_HUMAN | [view interactions] | High throughput | no | no |
SDC2_HUMAN | [view interactions] | High throughput | no | yes |
CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P2RY8_HUMAN | [view interactions] | High throughput | no | no |
HECD1_HUMAN | [view interactions] | High throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTAR1_HUMAN | [view interactions] | High throughput | no | yes |
GET4_HUMAN | [view interactions] | High throughput | no | yes |
PGM1_HUMAN | [view interactions] | High throughput | no | no |
SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BAKOR_HUMAN | [view interactions] | High throughput | no | yes |
RUBIC_HUMAN | [view interactions] | High throughput | no | no |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
APJ_HUMAN | [view interactions] | High throughput | no | yes |
ACM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IL1R2_HUMAN | [view interactions] | High throughput | no | no |
EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SNP23_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAB10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAB8A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MYO5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MYH9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RHOQ_HUMAN | [view interactions] | Computational | no | no |
ARHG2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EX3L4_HUMAN | [view interactions] | Computational | no | no |
RAB14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAB3I_HUMAN | [view interactions] | Computational | no | no |
STXB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DPH3_HUMAN | [view interactions] | Computational | no | no |
C2CD5_HUMAN | [view interactions] | Computational | no | yes |
LAP4B_HUMAN | [view interactions] | Computational | no | yes |
ARF6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CIP4_HUMAN | [view interactions] | Computational | no | no |
RAB13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TNAP2_HUMAN | [view interactions] | Computational | no | no |