EXOC2_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 28.1250 | 4 | no |
| GO:0031267 | small GTPase binding | 12.5000 | 5 | yes |
| GO:0051020 | GTPase binding | 12.5000 | 4 | yes |
| GO:0019900 | kinase binding | 9.3750 | 4 | yes |
| GO:0019901 | protein kinase binding | 9.3750 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC2_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 59.3750 | 4 | yes |
| GO:0071702 | organic substance transport | 50.0000 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 50.0000 | 4 | yes |
| GO:0015031 | protein transport | 43.7500 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 43.7500 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 43.7500 | 4 | no |
| GO:0046903 | secretion | 40.6250 | 4 | yes |
| GO:0010646 | regulation of cell communication | 37.5000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 37.5000 | 4 | no |
| GO:0006996 | organelle organization | 34.3750 | 4 | no |
| GO:0022607 | cellular component assembly | 34.3750 | 4 | no |
| GO:0000281 | mitotic cytokinesis | 31.2500 | 4 | yes |
| GO:0061024 | membrane organization | 31.2500 | 4 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 31.2500 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 31.2500 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 31.2500 | 4 | no |
| GO:0009966 | regulation of signal transduction | 31.2500 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 31.2500 | 4 | no |
| GO:0048278 | vesicle docking | 28.1250 | 4 | yes |
| GO:0090148 | membrane fission | 28.1250 | 5 | yes |
| GO:0099022 | vesicle tethering | 28.1250 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 28.1250 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 28.1250 | 5 | no |
| GO:0023056 | positive regulation of signaling | 28.1250 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 28.1250 | 4 | no |
| GO:0036211 | protein modification process | 28.1250 | 4 | no |
| GO:0043412 | macromolecule modification | 28.1250 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 25.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 25.0000 | 5 | no |
| GO:0010468 | regulation of gene expression | 25.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
| GO:0006892 | post-Golgi vesicle-mediated transport | 21.8750 | 4 | yes |
| GO:0006893 | Golgi to plasma membrane transport | 21.8750 | 4 | yes |
| GO:0010506 | regulation of autophagy | 21.8750 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 21.8750 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.8750 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 21.8750 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.8750 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.8750 | 5 | no |
| GO:0033365 | protein localization to organelle | 21.8750 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.8750 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.8750 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.8750 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.8750 | 5 | no |
| GO:0060341 | regulation of cellular localization | 21.8750 | 4 | no |
| GO:0052372 | modulation by symbiont of entry into host | 9.3750 | 4 | yes |
| GO:2000535 | regulation of entry of bacterium into host cell | 6.2500 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| EXOC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRGEF_HUMAN | [view interactions] | Low throughput | no | yes |
| RALB_HUMAN | [view interactions] | Low throughput | no | no |
| RALA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPS53_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| SCAR3_HUMAN | [view interactions] | High throughput | no | yes |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| LNX2_HUMAN | [view interactions] | High throughput | no | yes |
| EDNRB_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| GLPA_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| CD6_HUMAN | [view interactions] | High throughput | no | no |
| KI2L4_HUMAN | [view interactions] | High throughput | no | no |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| FXYD3_HUMAN | [view interactions] | High throughput | no | yes |
| P2Y10_HUMAN | [view interactions] | High throughput | no | no |
| VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| V2R_HUMAN | [view interactions] | High throughput | no | no |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| SDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2RY8_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| PTAR1_HUMAN | [view interactions] | High throughput | no | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| PGM1_HUMAN | [view interactions] | High throughput | no | no |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| DHX40_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KBTB4_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |
| BAKOR_HUMAN | [view interactions] | High throughput | no | yes |
| RUBIC_HUMAN | [view interactions] | High throughput | no | no |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| APJ_HUMAN | [view interactions] | High throughput | no | yes |
| ACM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| ESX1_HUMAN | [view interactions] | High throughput | no | no |
| CDN2A_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CTDP1_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| PK3C3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ULK1_HUMAN | [view interactions] | High throughput | no | no |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LPAR6_HUMAN | [view interactions] | High throughput | no | no |
| PE2R3_HUMAN | [view interactions] | High throughput | no | no |