ERLN2_HUMAN
Evidence for PS localization
Functions
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed, PubMed). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ERLN2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 30.7692 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 30.7692 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.7692 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 24.6154 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 24.6154 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 24.6154 | 6 | no |
| GO:0003723 | RNA binding | 24.6154 | 4 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 18.4615 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 16.9231 | 5 | yes |
| GO:0015485 | cholesterol binding | 4.6154 | 4 | yes |
| GO:0032934 | sterol binding | 4.6154 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ERLN2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 56.9231 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 52.3077 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 49.2308 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 47.6923 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.1538 | 4 | no |
| GO:0008104 | protein localization | 46.1538 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 40.0000 | 4 | yes |
| GO:0071702 | organic substance transport | 40.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.4615 | 4 | no |
| GO:0071705 | nitrogen compound transport | 38.4615 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.4615 | 4 | no |
| GO:0006996 | organelle organization | 36.9231 | 4 | no |
| GO:0010646 | regulation of cell communication | 36.9231 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.9231 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 35.3846 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 33.8462 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 33.8462 | 5 | yes |
| GO:0022607 | cellular component assembly | 33.8462 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.8462 | 5 | no |
| GO:0015031 | protein transport | 33.8462 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.3077 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.7692 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.7692 | 5 | no |
| GO:0071310 | cellular response to organic substance | 30.7692 | 4 | no |
| GO:0051049 | regulation of transport | 29.2308 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.2308 | 5 | no |
| GO:0009894 | regulation of catabolic process | 29.2308 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.6923 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.6923 | 5 | no |
| GO:0006886 | intracellular protein transport | 26.1538 | 4 | no |
| GO:0010941 | regulation of cell death | 26.1538 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.6154 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 24.6154 | 5 | no |
| GO:0033365 | protein localization to organelle | 24.6154 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 24.6154 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 24.6154 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.6154 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.6154 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 24.6154 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 23.0769 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 21.5385 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 21.5385 | 5 | yes |
| GO:0061024 | membrane organization | 21.5385 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.5385 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 21.5385 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.5385 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.5385 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 21.5385 | 5 | no |
| GO:0060341 | regulation of cellular localization | 21.5385 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.5385 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 21.5385 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 21.5385 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.5385 | 4 | no |
| GO:0006508 | proteolysis | 20.0000 | 4 | yes |
| GO:0034976 | response to endoplasmic reticulum stress | 20.0000 | 4 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 18.4615 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 18.4615 | 5 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 18.4615 | 4 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 18.4615 | 5 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 16.9231 | 7 | yes |
| GO:0030163 | protein catabolic process | 16.9231 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 16.9231 | 4 | yes |
| GO:0010498 | proteasomal protein catabolic process | 13.8462 | 5 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 13.8462 | 6 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 12.3077 | 5 | yes |
| GO:0036503 | ERAD pathway | 12.3077 | 5 | yes |
| GO:0030433 | ubiquitin-dependent ERAD pathway | 10.7692 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 10.7692 | 6 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 6.1538 | 4 | yes |
| GO:0008202 | steroid metabolic process | 4.6154 | 4 | yes |
| GO:0008203 | cholesterol metabolic process | 3.0769 | 5 | yes |
| GO:0010565 | regulation of cellular ketone metabolic process | 3.0769 | 5 | yes |
| GO:0010894 | negative regulation of steroid biosynthetic process | 3.0769 | 7 | yes |
| GO:0016125 | sterol metabolic process | 3.0769 | 4 | yes |
| GO:0019216 | regulation of lipid metabolic process | 3.0769 | 5 | yes |
| GO:0019217 | regulation of fatty acid metabolic process | 3.0769 | 6 | yes |
| GO:0019218 | regulation of steroid metabolic process | 3.0769 | 6 | yes |
| GO:0032933 | SREBP signaling pathway | 3.0769 | 4 | yes |
| GO:0042304 | regulation of fatty acid biosynthetic process | 3.0769 | 6 | yes |
| GO:0045540 | regulation of cholesterol biosynthetic process | 3.0769 | 6 | yes |
| GO:0045541 | negative regulation of cholesterol biosynthetic process | 3.0769 | 7 | yes |
| GO:0045717 | negative regulation of fatty acid biosynthetic process | 3.0769 | 7 | yes |
| GO:0045833 | negative regulation of lipid metabolic process | 3.0769 | 5 | yes |
| GO:0045922 | negative regulation of fatty acid metabolic process | 3.0769 | 6 | yes |
| GO:0045939 | negative regulation of steroid metabolic process | 3.0769 | 6 | yes |
| GO:0046890 | regulation of lipid biosynthetic process | 3.0769 | 5 | yes |
| GO:0050810 | regulation of steroid biosynthetic process | 3.0769 | 6 | yes |
| GO:0051055 | negative regulation of lipid biosynthetic process | 3.0769 | 6 | yes |
| GO:0062014 | negative regulation of small molecule metabolic process | 3.0769 | 5 | yes |
| GO:0071501 | cellular response to sterol depletion | 3.0769 | 4 | yes |
| GO:0090181 | regulation of cholesterol metabolic process | 3.0769 | 5 | yes |
| GO:0090206 | negative regulation of cholesterol metabolic process | 3.0769 | 6 | yes |
| GO:0106118 | regulation of sterol biosynthetic process | 3.0769 | 7 | yes |
| GO:0106119 | negative regulation of sterol biosynthetic process | 3.0769 | 8 | yes |
| GO:1902652 | secondary alcohol metabolic process | 3.0769 | 4 | yes |
| GO:1902930 | regulation of alcohol biosynthetic process | 3.0769 | 5 | yes |
| GO:1902931 | negative regulation of alcohol biosynthetic process | 3.0769 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ERLN2_HUMAN |
|---|---|---|---|---|
| DOID:1289 | neurodegenerative disease | 6.1538 | 4 | no |
| DOID:331 | central nervous system disease | 6.1538 | 3 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 4.6154 | 6 | no |
| DOID:440 | neuromuscular disease | 4.6154 | 5 | no |
| DOID:574 | peripheral nervous system disease | 4.6154 | 3 | no |
| DOID:870 | neuropathy | 4.6154 | 4 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 3.0769 | 7 | no |
| DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 3.0769 | 7 | no |
| DOID:12377 | spinal muscular atrophy | 3.0769 | 6 | no |
| DOID:231 | motor neuron disease | 3.0769 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| WLS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NICA_HUMAN | [view interactions] | Low throughput | no | yes |
| AMFR_HUMAN | [view interactions] | Low throughput | no | yes |
| INSI1_HUMAN | [view interactions] | Low throughput | no | no |
| RN170_HUMAN | [view interactions] | Low throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| RN185_HUMAN | [view interactions] | Low throughput | no | no |
| ITPR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCAP_HUMAN | [view interactions] | Low throughput | no | yes |
| SRBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| SRBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF5_HUMAN | [view interactions] | Low throughput | no | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK1_HUMAN | [view interactions] | Low throughput | no | no |
| CCNB1_HUMAN | [view interactions] | Low throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| CHSTA_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| GORS2_HUMAN | [view interactions] | High throughput | no | yes |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C7_HUMAN | [view interactions] | High throughput | no | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRL2_HUMAN | [view interactions] | High throughput | no | yes |
| PDCD6_HUMAN | [view interactions] | High throughput | no | no |
| MCU_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| RT12_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| HDA11_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| S38A1_HUMAN | [view interactions] | High throughput | no | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| KLH21_HUMAN | [view interactions] | High throughput | no | no |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| RN139_HUMAN | [view interactions] | High throughput | no | yes |
| TMUB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKB14_HUMAN | [view interactions] | High throughput | no | yes |
| AMGO1_HUMAN | [view interactions] | High throughput | no | yes |
| GSTM5_HUMAN | [view interactions] | High throughput | no | yes |
| GALNS_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| CLN6_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRC2B_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| TBA8_HUMAN | [view interactions] | High throughput | no | yes |
| UBAC2_HUMAN | [view interactions] | High throughput | no | yes |
| DUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MBRL_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK2_HUMAN | [view interactions] | High throughput | no | yes |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| HMDH_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| ICOS_HUMAN | [view interactions] | High throughput | no | no |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| TFDP1_HUMAN | [view interactions] | High throughput | no | yes |
| MIRO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA1D_HUMAN | [view interactions] | High throughput | no | no |
| PP6R3_HUMAN | [view interactions] | High throughput | no | yes |
| STK3_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TECT1_HUMAN | [view interactions] | High throughput | no | yes |
| MKS3_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| EPHAA_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASP8_HUMAN | [view interactions] | High throughput | no | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| CD3D_HUMAN | [view interactions] | High throughput | no | no |
| TFE2_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APH1A_HUMAN | [view interactions] | High throughput | no | yes |
| PEN2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| RIC3_HUMAN | [view interactions] | High throughput | no | yes |
| ARSK_HUMAN | [view interactions] | High throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD109_HUMAN | [view interactions] | High throughput | no | no |
| CA2D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| SEPR_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PODO_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| TMUB2_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXTP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| TM41B_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPAP_HUMAN | [view interactions] | High throughput | no | no |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |