NDUB4_HUMAN
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in NDUB4_HUMAN |
---|---|---|---|---|
GO:0015399 | primary active transmembrane transporter activity | 60.3774 | 4 | yes |
GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 56.6038 | 5 | yes |
GO:0003954 | NADH dehydrogenase activity | 43.3962 | 4 | yes |
GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | 43.3962 | 5 | yes |
GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 43.3962 | 4 | yes |
GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 43.3962 | 4 | yes |
GO:0050136 | NADH dehydrogenase (quinone) activity | 43.3962 | 5 | yes |
GO:0046872 | metal ion binding | 32.0755 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in NDUB4_HUMAN |
---|---|---|---|---|
GO:0009060 | aerobic respiration | 56.6038 | 6 | yes |
GO:0015980 | energy derivation by oxidation of organic compounds | 56.6038 | 4 | yes |
GO:0022900 | electron transport chain | 56.6038 | 4 | yes |
GO:0022904 | respiratory electron transport chain | 56.6038 | 5 | yes |
GO:0045333 | cellular respiration | 56.6038 | 5 | yes |
GO:0019646 | aerobic electron transport chain | 52.8302 | 6 | yes |
GO:0022607 | cellular component assembly | 52.8302 | 4 | yes |
GO:0043933 | protein-containing complex organization | 43.3962 | 4 | yes |
GO:0065003 | protein-containing complex assembly | 41.5094 | 5 | yes |
GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 39.6226 | 7 | yes |
GO:0033108 | mitochondrial respiratory chain complex assembly | 35.8491 | 6 | yes |
GO:0010257 | NADH dehydrogenase complex assembly | 33.9623 | 6 | yes |
GO:0032981 | mitochondrial respiratory chain complex I assembly | 33.9623 | 7 | yes |
GO:0048523 | negative regulation of cellular process | 26.4151 | 4 | no |
GO:0006996 | organelle organization | 24.5283 | 4 | no |
GO:0009966 | regulation of signal transduction | 22.6415 | 4 | no |
GO:0010646 | regulation of cell communication | 22.6415 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 22.6415 | 4 | no |
GO:0048522 | positive regulation of cellular process | 22.6415 | 4 | no |
GO:0051128 | regulation of cellular component organization | 22.6415 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 20.7547 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 20.7547 | 4 | no |
GO:0008104 | protein localization | 20.7547 | 4 | no |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NDUB3_HUMAN | [view interactions] | Low throughput | no | yes |
NDUA1_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB1_HUMAN | [view interactions] | Low throughput | no | yes |
NDUA3_HUMAN | [view interactions] | Low throughput | no | yes |
NDUC2_HUMAN | [view interactions] | Low throughput | no | yes |
NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUBA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB5_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB2_HUMAN | [view interactions] | Low throughput | no | yes |
NU4LM_HUMAN | [view interactions] | Low throughput | no | no |
NU2M_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NU4M_HUMAN | [view interactions] | Low throughput | no | yes |
NU6M_HUMAN | [view interactions] | Low throughput | no | no |
NDUB8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NU1M_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUC1_HUMAN | [view interactions] | Low throughput | no | yes |
NU3M_HUMAN | [view interactions] | Low throughput | no | yes |
NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NU5M_HUMAN | [view interactions] | Low throughput | no | no |
NDUB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUS5_HUMAN | [view interactions] | Low throughput | no | yes |
NDUAB_HUMAN | [view interactions] | Low throughput | no | no |
ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
NDUA8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUBB_HUMAN | [view interactions] | Low throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
INS_HUMAN | [view interactions] | High throughput | no | no |
CFAD_HUMAN | [view interactions] | High throughput | no | no |
FNDC5_HUMAN | [view interactions] | High throughput | no | no |
DX39A_HUMAN | [view interactions] | High throughput | no | yes |
NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRIL_HUMAN | [view interactions] | High throughput | no | yes |
NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
FUT1_HUMAN | [view interactions] | High throughput | no | no |
SCAR3_HUMAN | [view interactions] | High throughput | no | yes |
FFAR1_HUMAN | [view interactions] | High throughput | no | no |
DRB1_HUMAN | [view interactions] | High throughput | no | no |
DJC30_HUMAN | [view interactions] | High throughput | no | no |
SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
T2EA_HUMAN | [view interactions] | High throughput | no | yes |
BACD3_HUMAN | [view interactions] | High throughput | no | yes |
C560_HUMAN | [view interactions] | High throughput | no | no |
QCR7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ML12A_HUMAN | [view interactions] | High throughput | no | no |
MPV17_HUMAN | [view interactions] | High throughput | no | no |
MPRD_HUMAN | [view interactions] | High throughput | no | yes |
TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LTOR3_HUMAN | [view interactions] | High throughput | no | yes |
MARC1_HUMAN | [view interactions] | High throughput | no | yes |
ABCD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TOM5_HUMAN | [view interactions] | High throughput | no | yes |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUCR_HUMAN | [view interactions] | High throughput | no | yes |
NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
KSR1_HUMAN | [view interactions] | High throughput | no | yes |
NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NMES1_HUMAN | [view interactions] | High throughput | no | no |
CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COQ9_HUMAN | [view interactions] | High throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NEP_HUMAN | [view interactions] | High throughput | no | no |
NDUA6_HUMAN | [view interactions] | High throughput | no | no |
HSC20_HUMAN | [view interactions] | High throughput | no | yes |
KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
CAV3_HUMAN | [view interactions] | High throughput | no | no |
ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FTM_HUMAN | [view interactions] | High throughput | no | yes |
TFE2_HUMAN | [view interactions] | High throughput | no | no |
ENPP6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP4R1_HUMAN | [view interactions] | High throughput | no | yes |
GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
BMR1A_HUMAN | [view interactions] | High throughput | no | no |
RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMED2_HUMAN | [view interactions] | High throughput | no | yes |
RMD3_HUMAN | [view interactions] | High throughput | no | yes |
KCTD5_HUMAN | [view interactions] | High throughput | no | no |
CDC16_HUMAN | [view interactions] | High throughput | no | yes |
ERC6L_HUMAN | [view interactions] | High throughput | no | yes |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
ATPMK_HUMAN | [view interactions] | Computational | no | no |
NDUS8_HUMAN | [view interactions] | Computational | no | yes |
COX41_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
QCR9_HUMAN | [view interactions] | Computational | no | no |
QCR10_HUMAN | [view interactions] | Computational | no | no |
COX7C_HUMAN | [view interactions] | Computational | no | yes |
CYB_HUMAN | [view interactions] | Computational | no | yes |
QCR8_HUMAN | [view interactions] | Computational | no | yes |
QCR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
QCR6_HUMAN | [view interactions] | Computational | no | yes |
ATP5J_HUMAN | [view interactions] | Computational | no | yes |
CY1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CIA30_HUMAN | [view interactions] | Computational | no | yes |
QCR2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ATPK_HUMAN | [view interactions] | Computational | no | yes |
COX5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
COX5B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |