NDUB6_HUMAN
Evidence for PS localization
Functions
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDUB6_HUMAN |
|---|---|---|---|---|
| GO:0015399 | primary active transmembrane transporter activity | 73.1707 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 73.1707 | 5 | yes |
| GO:0003954 | NADH dehydrogenase activity | 56.0976 | 4 | yes |
| GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | 56.0976 | 5 | yes |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 56.0976 | 4 | yes |
| GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 56.0976 | 4 | yes |
| GO:0050136 | NADH dehydrogenase (quinone) activity | 56.0976 | 5 | yes |
| GO:0046872 | metal ion binding | 41.4634 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDUB6_HUMAN |
|---|---|---|---|---|
| GO:0009060 | aerobic respiration | 75.6098 | 6 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 75.6098 | 4 | yes |
| GO:0022900 | electron transport chain | 75.6098 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 75.6098 | 5 | yes |
| GO:0045333 | cellular respiration | 75.6098 | 5 | yes |
| GO:0019646 | aerobic electron transport chain | 70.7317 | 6 | yes |
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 51.2195 | 7 | yes |
| GO:0022607 | cellular component assembly | 51.2195 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 51.2195 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 51.2195 | 5 | yes |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 46.3415 | 6 | yes |
| GO:0010257 | NADH dehydrogenase complex assembly | 43.9024 | 6 | yes |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | 43.9024 | 7 | yes |
| GO:0042773 | ATP synthesis coupled electron transport | 12.1951 | 6 | yes |
| GO:0042775 | mitochondrial ATP synthesis coupled electron transport | 12.1951 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NDUS3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS5_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAB_HUMAN | [view interactions] | Low throughput | no | no |
| NDUA8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB5_HUMAN | [view interactions] | Low throughput | no | yes |
| CIA30_HUMAN | [view interactions] | Low throughput | no | yes |
| ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
| YMEL1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUBB_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUC2_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB1_HUMAN | [view interactions] | Low throughput | no | yes |
| NU5M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUC1_HUMAN | [view interactions] | Low throughput | no | yes |
| NU3M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU4LM_HUMAN | [view interactions] | Low throughput | no | no |
| NU2M_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NDUB2_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU6M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU1M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU4M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF19_HUMAN | [view interactions] | High throughput | no | yes |
| YIPF3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUT1_HUMAN | [view interactions] | High throughput | no | no |
| GALT6_HUMAN | [view interactions] | High throughput | no | yes |
| PON1_HUMAN | [view interactions] | High throughput | no | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LFG4_HUMAN | [view interactions] | High throughput | no | no |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| CREB3_HUMAN | [view interactions] | High throughput | no | no |
| FOXL2_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CREL1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA8_HUMAN | [view interactions] | High throughput | no | no |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| EMC3_HUMAN | [view interactions] | High throughput | no | yes |
| SNX17_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| MPV17_HUMAN | [view interactions] | High throughput | no | no |
| ABCB7_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5E_HUMAN | [view interactions] | High throughput | no | no |
| ACBP_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| T10B_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT5F1_HUMAN | [view interactions] | Computational | no | yes |
| ATP5J_HUMAN | [view interactions] | Computational | no | yes |
| C560_HUMAN | [view interactions] | Computational | no | no |
| QCR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX5B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DHSD_HUMAN | [view interactions] | Computational | no | yes |
| QCR7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MPC1_HUMAN | [view interactions] | Computational | no | yes |
| NDUCR_HUMAN | [view interactions] | Computational | no | yes |
| NDUS8_HUMAN | [view interactions] | Computational | no | yes |
| ODO2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ATPO_HUMAN | [view interactions] | Computational | no | yes |
| CX6A1_HUMAN | [view interactions] | Computational | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX1_HUMAN | [view interactions] | Computational | no | yes |
| CYB_HUMAN | [view interactions] | Computational | no | yes |
| COX7C_HUMAN | [view interactions] | Computational | no | yes |
| FXRD1_HUMAN | [view interactions] | Computational | no | no |
| QCR8_HUMAN | [view interactions] | Computational | no | yes |
| QCR9_HUMAN | [view interactions] | Computational | no | no |
| NDUA4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| QCR10_HUMAN | [view interactions] | Computational | no | no |