OLA1_HUMAN
Evidence for PS localization
Functions
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in OLA1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 40.0000 | 4 | no |
| GO:0000166 | nucleotide binding | 31.6667 | 4 | yes |
| GO:0043168 | anion binding | 30.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 28.3333 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.3333 | 4 | yes |
| GO:0043169 | cation binding | 23.3333 | 4 | yes |
| GO:0046872 | metal ion binding | 23.3333 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 20.0000 | 6 | yes |
| GO:0045296 | cadherin binding | 18.3333 | 4 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 16.6667 | 5 | yes |
| GO:0005524 | ATP binding | 15.0000 | 5 | yes |
| GO:0016462 | pyrophosphatase activity | 13.3333 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 13.3333 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 13.3333 | 6 | yes |
| GO:0005525 | GTP binding | 10.0000 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 10.0000 | 6 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 10.0000 | 5 | yes |
| GO:0016887 | ATP hydrolysis activity | 6.6667 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in OLA1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 46.6667 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 45.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.3333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.3333 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 41.6667 | 4 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 40.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 40.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.0000 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 38.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.3333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.6667 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.6667 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 35.0000 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 33.3333 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 31.6667 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.6667 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.6667 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 30.0000 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 30.0000 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 30.0000 | 5 | no |
| GO:0008104 | protein localization | 30.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.0000 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 30.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 28.3333 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.3333 | 5 | no |
| GO:0071310 | cellular response to organic substance | 28.3333 | 4 | no |
| GO:0022607 | cellular component assembly | 28.3333 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 28.3333 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 28.3333 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.6667 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 26.6667 | 5 | no |
| GO:0036211 | protein modification process | 26.6667 | 4 | no |
| GO:0043412 | macromolecule modification | 26.6667 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.6667 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 26.6667 | 7 | no |
| GO:0010648 | negative regulation of cell communication | 26.6667 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.6667 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.6667 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.6667 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.6667 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 25.0000 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 23.3333 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.3333 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 23.3333 | 6 | no |
| GO:0031399 | regulation of protein modification process | 23.3333 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.3333 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 23.3333 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.3333 | 6 | no |
| GO:0009894 | regulation of catabolic process | 21.6667 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 21.6667 | 7 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.6667 | 5 | no |
| GO:0033043 | regulation of organelle organization | 21.6667 | 5 | no |
| GO:0006412 | translation | 21.6667 | 4 | no |
| GO:0006163 | purine nucleotide metabolic process | 18.3333 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 18.3333 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 18.3333 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 18.3333 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 18.3333 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 18.3333 | 4 | yes |
| GO:0072521 | purine-containing compound metabolic process | 18.3333 | 4 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 15.0000 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 15.0000 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 15.0000 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 15.0000 | 7 | yes |
| GO:0046034 | ATP metabolic process | 15.0000 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| TBG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BARD1_HUMAN | [view interactions] | Low throughput | no | yes |
| RACK1_HUMAN | [view interactions] | Low throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| SHOC2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| HMGA1_HUMAN | [view interactions] | High throughput | no | yes |
| BCL6_HUMAN | [view interactions] | High throughput | no | no |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| GPC5C_HUMAN | [view interactions] | High throughput | no | no |
| SGK1_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| ASCC2_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| LMTK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LSM8_HUMAN | [view interactions] | High throughput | no | yes |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| THOC4_HUMAN | [view interactions] | High throughput | no | no |
| PRPF3_HUMAN | [view interactions] | High throughput | no | yes |
| PPIH_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| RL26L_HUMAN | [view interactions] | High throughput | no | yes |
| LSM4_HUMAN | [view interactions] | High throughput | no | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN346_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CDX2_HUMAN | [view interactions] | High throughput | no | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| BACH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF8_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIC_HUMAN | [view interactions] | High throughput | no | yes |
| ASNS_HUMAN | [view interactions] | High throughput | no | yes |
| RUXE_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDGF_HUMAN | [view interactions] | High throughput | no | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSHB_HUMAN | [view interactions] | High throughput | no | no |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUXF_HUMAN | [view interactions] | High throughput | no | no |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| GNL3L_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| PYRD_HUMAN | [view interactions] | High throughput | no | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THNS2_HUMAN | [view interactions] | High throughput | no | no |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAD1_HUMAN | [view interactions] | High throughput | no | no |
| MAST4_HUMAN | [view interactions] | High throughput | no | no |
| AGM1_HUMAN | [view interactions] | High throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAMPT_HUMAN | [view interactions] | High throughput | no | no |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPA_HUMAN | [view interactions] | High throughput | no | yes |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| ITPA_HUMAN | [view interactions] | High throughput | no | yes |
| NEUL_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| MORC2_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |