CPT1A_HUMAN
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed, PubMed, PubMed). Plays an important role in hepatic triglyceride metabolism . [View more on UniProt]
Interacting region for partners were not defined.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in CPT1A_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 31.6667 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 31.6667 | 4 | no |
GO:0046872 | metal ion binding | 30.0000 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 30.0000 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 23.3333 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 23.3333 | 5 | no |
GO:0015399 | primary active transmembrane transporter activity | 23.3333 | 4 | no |
GO:0005524 | ATP binding | 21.6667 | 5 | no |
GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | 10.0000 | 4 | yes |
GO:0004095 | carnitine O-palmitoyltransferase activity | 5.0000 | 7 | yes |
GO:0008374 | O-acyltransferase activity | 5.0000 | 5 | yes |
GO:0016406 | carnitine O-acyltransferase activity | 5.0000 | 6 | yes |
GO:0016409 | palmitoyltransferase activity | 5.0000 | 5 | yes |
GO:0016416 | O-palmitoyltransferase activity | 5.0000 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in CPT1A_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 48.3333 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 43.3333 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 40.0000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 40.0000 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 36.6667 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 36.6667 | 4 | no |
GO:0048523 | negative regulation of cellular process | 35.0000 | 4 | no |
GO:0010646 | regulation of cell communication | 35.0000 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 33.3333 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | yes |
GO:0071310 | cellular response to organic substance | 31.6667 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 30.0000 | 5 | no |
GO:0022607 | cellular component assembly | 30.0000 | 4 | no |
GO:0051128 | regulation of cellular component organization | 30.0000 | 4 | no |
GO:0010243 | response to organonitrogen compound | 30.0000 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 28.3333 | 6 | no |
GO:0009966 | regulation of signal transduction | 28.3333 | 4 | no |
GO:0010468 | regulation of gene expression | 28.3333 | 5 | no |
GO:0006996 | organelle organization | 28.3333 | 4 | no |
GO:0051049 | regulation of transport | 28.3333 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 26.6667 | 4 | no |
GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
GO:0010941 | regulation of cell death | 25.0000 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
GO:0043067 | regulation of programmed cell death | 25.0000 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 25.0000 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
GO:0071702 | organic substance transport | 25.0000 | 4 | yes |
GO:0031399 | regulation of protein modification process | 23.3333 | 6 | no |
GO:0048584 | positive regulation of response to stimulus | 23.3333 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 23.3333 | 5 | no |
GO:0042325 | regulation of phosphorylation | 21.6667 | 7 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 21.6667 | 7 | no |
GO:0009967 | positive regulation of signal transduction | 21.6667 | 5 | no |
GO:1901701 | cellular response to oxygen-containing compound | 21.6667 | 4 | yes |
GO:0006811 | ion transport | 21.6667 | 4 | no |
GO:0008104 | protein localization | 21.6667 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 21.6667 | 6 | no |
GO:0019752 | carboxylic acid metabolic process | 20.0000 | 5 | yes |
GO:0043436 | oxoacid metabolic process | 20.0000 | 4 | yes |
GO:0032787 | monocarboxylic acid metabolic process | 18.3333 | 6 | yes |
GO:0060341 | regulation of cellular localization | 18.3333 | 4 | yes |
GO:0014070 | response to organic cyclic compound | 16.6667 | 4 | yes |
GO:0009894 | regulation of catabolic process | 15.0000 | 4 | yes |
GO:0032880 | regulation of protein localization | 15.0000 | 5 | yes |
GO:0006631 | fatty acid metabolic process | 13.3333 | 4 | yes |
GO:0033993 | response to lipid | 11.6667 | 4 | yes |
GO:0051046 | regulation of secretion | 11.6667 | 5 | yes |
GO:0051223 | regulation of protein transport | 11.6667 | 5 | yes |
GO:0070201 | regulation of establishment of protein localization | 11.6667 | 6 | yes |
GO:0071396 | cellular response to lipid | 11.6667 | 5 | yes |
GO:0016042 | lipid catabolic process | 10.0000 | 4 | yes |
GO:0019216 | regulation of lipid metabolic process | 10.0000 | 5 | yes |
GO:0031329 | regulation of cellular catabolic process | 10.0000 | 5 | yes |
GO:1903530 | regulation of secretion by cell | 10.0000 | 4 | yes |
GO:0006635 | fatty acid beta-oxidation | 8.3333 | 6 | yes |
GO:0009062 | fatty acid catabolic process | 8.3333 | 5 | yes |
GO:0009896 | positive regulation of catabolic process | 8.3333 | 5 | yes |
GO:0015849 | organic acid transport | 8.3333 | 5 | yes |
GO:0016054 | organic acid catabolic process | 8.3333 | 4 | yes |
GO:0019395 | fatty acid oxidation | 8.3333 | 5 | yes |
GO:0030258 | lipid modification | 8.3333 | 4 | yes |
GO:0031667 | response to nutrient levels | 8.3333 | 4 | yes |
GO:0034440 | lipid oxidation | 8.3333 | 5 | yes |
GO:0044242 | cellular lipid catabolic process | 8.3333 | 4 | yes |
GO:0046395 | carboxylic acid catabolic process | 8.3333 | 5 | yes |
GO:0072329 | monocarboxylic acid catabolic process | 8.3333 | 6 | yes |
GO:0001676 | long-chain fatty acid metabolic process | 6.6667 | 5 | yes |
GO:0006839 | mitochondrial transport | 6.6667 | 4 | yes |
GO:0006869 | lipid transport | 6.6667 | 5 | yes |
GO:0015908 | fatty acid transport | 6.6667 | 6 | yes |
GO:0015909 | long-chain fatty acid transport | 6.6667 | 7 | yes |
GO:0031331 | positive regulation of cellular catabolic process | 6.6667 | 6 | yes |
GO:0043279 | response to alkaloid | 6.6667 | 5 | yes |
GO:0045834 | positive regulation of lipid metabolic process | 6.6667 | 5 | yes |
GO:0048732 | gland development | 6.6667 | 4 | yes |
GO:0062012 | regulation of small molecule metabolic process | 6.6667 | 4 | yes |
GO:1905039 | carboxylic acid transmembrane transport | 6.6667 | 4 | yes |
GO:0002791 | regulation of peptide secretion | 5.0000 | 6 | yes |
GO:0006006 | glucose metabolic process | 5.0000 | 5 | yes |
GO:0006577 | amino-acid betaine metabolic process | 5.0000 | 4 | yes |
GO:0009437 | carnitine metabolic process | 5.0000 | 5 | yes |
GO:0019318 | hexose metabolic process | 5.0000 | 4 | yes |
GO:0030855 | epithelial cell differentiation | 5.0000 | 4 | yes |
GO:0046883 | regulation of hormone secretion | 5.0000 | 4 | yes |
GO:0050708 | regulation of protein secretion | 5.0000 | 5 | yes |
GO:0050796 | regulation of insulin secretion | 5.0000 | 6 | yes |
GO:0090087 | regulation of peptide transport | 5.0000 | 5 | yes |
GO:0090276 | regulation of peptide hormone secretion | 5.0000 | 5 | yes |
GO:1902001 | fatty acid transmembrane transport | 5.0000 | 5 | yes |
GO:0001889 | liver development | 3.3333 | 5 | yes |
GO:0006853 | carnitine shuttle | 3.3333 | 4 | yes |
GO:0010565 | regulation of cellular ketone metabolic process | 3.3333 | 5 | yes |
GO:0019217 | regulation of fatty acid metabolic process | 3.3333 | 6 | yes |
GO:0032365 | intracellular lipid transport | 3.3333 | 4 | yes |
GO:0045471 | response to ethanol | 3.3333 | 5 | yes |
GO:0046486 | glycerolipid metabolic process | 3.3333 | 4 | yes |
GO:0062013 | positive regulation of small molecule metabolic process | 3.3333 | 5 | yes |
GO:0097305 | response to alcohol | 3.3333 | 4 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in CPT1A_HUMAN |
---|---|---|---|---|
DOID:3146 | lipid metabolism disorder | 3.3333 | 3 | yes |
DOID:0060038 | specific developmental disorder | 3.3333 | 3 | no |
DOID:1059 | intellectual disability | 3.3333 | 4 | no |
DOID:331 | central nervous system disease | 3.3333 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
BCL2_HUMAN | [view interactions] | Low throughput | no | no |
LDHA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VSIG4_HUMAN | [view interactions] | High throughput | no | no |
KLRD1_HUMAN | [view interactions] | High throughput | no | no |
ADAM7_HUMAN | [view interactions] | High throughput | no | no |
T184A_HUMAN | [view interactions] | High throughput | no | no |
SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
THB_HUMAN | [view interactions] | High throughput | no | no |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPSM_HUMAN | [view interactions] | High throughput | no | no |
LPP_HUMAN | [view interactions] | High throughput | no | yes |
TOM40_HUMAN | [view interactions] | High throughput | no | yes |
VATC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U520_HUMAN | [view interactions] | High throughput | no | yes |
HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EMC4_HUMAN | [view interactions] | High throughput | no | yes |
NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ODBA_HUMAN | [view interactions] | High throughput | no | yes |
VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EMC2_HUMAN | [view interactions] | High throughput | no | yes |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YIPF3_HUMAN | [view interactions] | High throughput | no | yes |
PLOD3_HUMAN | [view interactions] | High throughput | no | yes |
EMC3_HUMAN | [view interactions] | High throughput | no | yes |
ATPB_HUMAN | [view interactions] | High throughput | no | yes |
COX7C_HUMAN | [view interactions] | High throughput | no | yes |
ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TOM5_HUMAN | [view interactions] | High throughput | no | yes |
CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGR2_HUMAN | [view interactions] | High throughput | no | no |
OPTN_HUMAN | [view interactions] | High throughput | no | yes |
TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
CY24A_HUMAN | [view interactions] | High throughput | no | no |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NPDC1_HUMAN | [view interactions] | High throughput | no | yes |
HDA11_HUMAN | [view interactions] | High throughput | no | no |
TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
PP4C_HUMAN | [view interactions] | High throughput | no | yes |
KCNK1_HUMAN | [view interactions] | High throughput | no | yes |
HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDR5_HUMAN | [view interactions] | High throughput | no | no |
TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
COQ9_HUMAN | [view interactions] | High throughput | no | yes |
NMES1_HUMAN | [view interactions] | High throughput | no | no |
NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ELK1_HUMAN | [view interactions] | High throughput | no | yes |
KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SDHA_HUMAN | [view interactions] | High throughput | no | yes |
E2F3_HUMAN | [view interactions] | High throughput | no | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYPC3_HUMAN | [view interactions] | High throughput | no | no |
INSR_HUMAN | [view interactions] | High throughput | no | yes |
RYBP_HUMAN | [view interactions] | High throughput | no | no |
CLIC1_HUMAN | [view interactions] | High throughput | no | no |
KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
TIFAB_HUMAN | [view interactions] | High throughput | no | no |
CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLN3_HUMAN | [view interactions] | High throughput | no | no |
PCKGC_HUMAN | [view interactions] | High throughput | no | no |
FBX6_HUMAN | [view interactions] | High throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LGR4_HUMAN | [view interactions] | High throughput | no | yes |
ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
RING2_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
HERC2_HUMAN | [view interactions] | High throughput | no | yes |
WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
TBCD9_HUMAN | [view interactions] | High throughput | no | yes |
GBRG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
PRP8_HUMAN | [view interactions] | High throughput | no | yes |
PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
PPT1_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H4_HUMAN | [view interactions] | High throughput | no | yes |
LMBRL_HUMAN | [view interactions] | High throughput | no | no |
EMC1_HUMAN | [view interactions] | High throughput | no | yes |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
INS_HUMAN | [view interactions] | High throughput | no | no |
RMC1_HUMAN | [view interactions] | High throughput | no | no |
NPC1_HUMAN | [view interactions] | High throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F16P1_HUMAN | [view interactions] | High throughput | no | no |
P53_HUMAN | [view interactions] | High throughput | no | no |
AT2B2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD1A_HUMAN | [view interactions] | High throughput | no | no |
CKLF5_HUMAN | [view interactions] | High throughput | no | yes |
DQB1_HUMAN | [view interactions] | High throughput | no | no |
S22A4_HUMAN | [view interactions] | High throughput | no | yes |
S39A9_HUMAN | [view interactions] | High throughput | no | yes |
TTYH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
INLR1_HUMAN | [view interactions] | High throughput | no | no |
AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TMM59_HUMAN | [view interactions] | High throughput | no | yes |
MAGA8_HUMAN | [view interactions] | High throughput | no | no |
CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAMP2_HUMAN | [view interactions] | High throughput | no | no |
PCDGM_HUMAN | [view interactions] | High throughput | no | yes |
TSN8_HUMAN | [view interactions] | High throughput | no | no |
AT1A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AQP3_HUMAN | [view interactions] | High throughput | no | no |
GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DOXA2_HUMAN | [view interactions] | High throughput | no | no |
EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITLN1_HUMAN | [view interactions] | High throughput | no | no |
GP182_HUMAN | [view interactions] | High throughput | no | no |
GPR45_HUMAN | [view interactions] | High throughput | no | no |
HLAC_HUMAN | [view interactions] | High throughput | no | no |
NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
GPIX_HUMAN | [view interactions] | High throughput | no | no |
CPT1B_HUMAN | [view interactions] | Computational | no | no |
PPARA_HUMAN | [view interactions] | Computational | no | yes |
FAS_HUMAN | [view entry] [view interactions] | Computational | yes | no |
EP300_HUMAN | [view interactions] | Computational | no | yes |
ECHP_HUMAN | [view interactions] | Computational | no | no |
NCOA2_HUMAN | [view interactions] | Computational | no | no |
JUN_HUMAN | [view interactions] | Computational | no | yes |
SRA1_HUMAN | [view interactions] | Computational | no | yes |
CBP_HUMAN | [view interactions] | Computational | no | yes |
APOA1_HUMAN | [view interactions] | Computational | no | no |
RORA_HUMAN | [view interactions] | Computational | no | yes |
CARM1_HUMAN | [view interactions] | Computational | no | yes |
TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MAOX_HUMAN | [view interactions] | Computational | no | yes |
MCAT_HUMAN | [view interactions] | Computational | no | yes |
ACSL3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ACSL5_HUMAN | [view interactions] | Computational | no | yes |
SP1_HUMAN | [view interactions] | Computational | no | yes |
TGS1_HUMAN | [view interactions] | Computational | no | yes |
TBL1R_HUMAN | [view interactions] | Computational | no | yes |
CPT2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NCOA1_HUMAN | [view interactions] | Computational | no | yes |
PRGC1_HUMAN | [view interactions] | Computational | no | no |
ACSL1_HUMAN | [view interactions] | Computational | no | no |
ACOX1_HUMAN | [view interactions] | Computational | no | yes |
SRBP1_HUMAN | [view interactions] | Computational | no | yes |
ACSL4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NCOA6_HUMAN | [view interactions] | Computational | no | yes |
CPT1C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SMRD3_HUMAN | [view interactions] | Computational | no | no |
CHD9_HUMAN | [view interactions] | Computational | no | yes |
MED1_HUMAN | [view interactions] | Computational | no | no |
RXRA_HUMAN | [view interactions] | Computational | no | yes |
APOA2_HUMAN | [view interactions] | Computational | no | no |
ACACB_HUMAN | [view interactions] | Computational | no | no |
RAB28_HUMAN | [view interactions] | Computational | no | yes |
HELZ2_HUMAN | [view interactions] | Computational | no | no |
NRIP1_HUMAN | [view interactions] | Computational | no | yes |
FABPL_HUMAN | [view interactions] | Computational | no | no |