Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

UBP50_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Has no peptidase activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in UBP50_HUMAN
GO:0000166 nucleotide binding 60.0000 4 no
GO:0017076 purine nucleotide binding 60.0000 5 no
GO:0032555 purine ribonucleotide binding 60.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 60.0000 4 no
GO:0043168 anion binding 60.0000 4 no
GO:0005524 ATP binding 45.0000 5 no
GO:0030554 adenyl nucleotide binding 45.0000 6 no
GO:0032559 adenyl ribonucleotide binding 45.0000 5 no
GO:0016462 pyrophosphatase activity 45.0000 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 45.0000 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 45.0000 6 no
GO:0003723 RNA binding 35.0000 4 no
GO:0016887 ATP hydrolysis activity 35.0000 7 no
GO:0042803 protein homodimerization activity 30.0000 4 no
GO:0031625 ubiquitin protein ligase binding 25.0000 5 no
GO:0044389 ubiquitin-like protein ligase binding 25.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in UBP50_HUMAN
GO:0031323 regulation of cellular metabolic process 55.0000 4 yes
GO:0080090 regulation of primary metabolic process 50.0000 4 yes
GO:0048522 positive regulation of cellular process 50.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 yes
GO:0006996 organelle organization 45.0000 4 yes
GO:0009889 regulation of biosynthetic process 45.0000 4 yes
GO:0009893 positive regulation of metabolic process 45.0000 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 45.0000 5 yes
GO:0031325 positive regulation of cellular metabolic process 45.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 45.0000 5 yes
GO:0051049 regulation of transport 40.0000 4 no
GO:0071702 organic substance transport 40.0000 4 no
GO:0009891 positive regulation of biosynthetic process 40.0000 5 yes
GO:0010468 regulation of gene expression 40.0000 6 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 40.0000 6 yes
GO:0010604 positive regulation of macromolecule metabolic process 40.0000 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 40.0000 6 yes
GO:0051246 regulation of protein metabolic process 40.0000 5 yes
GO:0008104 protein localization 35.0000 4 no
GO:0031399 regulation of protein modification process 35.0000 6 no
GO:0032880 regulation of protein localization 35.0000 5 no
GO:0048523 negative regulation of cellular process 35.0000 4 no
GO:0048584 positive regulation of response to stimulus 35.0000 4 no
GO:0060341 regulation of cellular localization 35.0000 4 no
GO:0014070 response to organic cyclic compound 35.0000 4 no
GO:0010628 positive regulation of gene expression 35.0000 7 yes
GO:0051128 regulation of cellular component organization 35.0000 4 yes
GO:0051240 positive regulation of multicellular organismal process 35.0000 4 yes
GO:0051247 positive regulation of protein metabolic process 35.0000 6 yes
GO:0009892 negative regulation of metabolic process 30.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 30.0000 5 no
GO:0071705 nitrogen compound transport 30.0000 4 no
GO:0009894 regulation of catabolic process 30.0000 4 no
GO:0010646 regulation of cell communication 30.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 30.0000 5 no
GO:0042981 regulation of apoptotic process 30.0000 5 no
GO:0043067 regulation of programmed cell death 30.0000 4 no
GO:0071310 cellular response to organic substance 30.0000 4 no
GO:0043933 protein-containing complex organization 30.0000 4 no
GO:0044087 regulation of cellular component biogenesis 30.0000 4 yes
GO:0001932 regulation of protein phosphorylation 25.0000 7 no
GO:0002684 positive regulation of immune system process 25.0000 4 no
GO:0002831 regulation of response to biotic stimulus 25.0000 4 no
GO:0006886 intracellular protein transport 25.0000 4 no
GO:0015031 protein transport 25.0000 4 no
GO:0019220 regulation of phosphate metabolic process 25.0000 6 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0031347 regulation of defense response 25.0000 5 no
GO:0032101 regulation of response to external stimulus 25.0000 4 no
GO:0033365 protein localization to organelle 25.0000 5 no
GO:0042325 regulation of phosphorylation 25.0000 7 no
GO:0045088 regulation of innate immune response 25.0000 5 no
GO:0050776 regulation of immune response 25.0000 4 no
GO:0051174 regulation of phosphorus metabolic process 25.0000 5 no
GO:0051223 regulation of protein transport 25.0000 5 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:0051726 regulation of cell cycle 25.0000 4 no
GO:0070201 regulation of establishment of protein localization 25.0000 6 no
GO:0072594 establishment of protein localization to organelle 25.0000 4 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:1903829 positive regulation of protein localization 25.0000 5 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 no
GO:0009057 macromolecule catabolic process 25.0000 4 no
GO:0009059 macromolecule biosynthetic process 25.0000 4 no
GO:0009896 positive regulation of catabolic process 25.0000 5 no
GO:0009966 regulation of signal transduction 25.0000 4 no
GO:0009967 positive regulation of signal transduction 25.0000 5 no
GO:0010243 response to organonitrogen compound 25.0000 4 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0031396 regulation of protein ubiquitination 25.0000 9 no
GO:0033993 response to lipid 25.0000 4 no
GO:0042176 regulation of protein catabolic process 25.0000 5 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0045595 regulation of cell differentiation 25.0000 4 no
GO:0045597 positive regulation of cell differentiation 25.0000 5 no
GO:0051094 positive regulation of developmental process 25.0000 4 no
GO:0061024 membrane organization 25.0000 4 no
GO:0071396 cellular response to lipid 25.0000 5 no
GO:1901873 regulation of post-translational protein modification 25.0000 7 no
GO:1903320 regulation of protein modification by small protein conjugation or removal 25.0000 8 no
GO:0022607 cellular component assembly 25.0000 4 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:0090304 nucleic acid metabolic process 25.0000 4 no
GO:1901362 organic cyclic compound biosynthetic process 25.0000 4 no
GO:0019752 carboxylic acid metabolic process 25.0000 5 no
GO:0043436 oxoacid metabolic process 25.0000 4 no
GO:0001817 regulation of cytokine production 25.0000 4 yes
GO:0001819 positive regulation of cytokine production 25.0000 5 yes
GO:0030162 regulation of proteolysis 25.0000 6 yes
GO:0043085 positive regulation of catalytic activity 25.0000 4 yes
GO:0043254 regulation of protein-containing complex assembly 25.0000 5 yes
GO:0031334 positive regulation of protein-containing complex assembly 20.0000 6 yes
GO:0044089 positive regulation of cellular component biogenesis 20.0000 5 yes
GO:0045862 positive regulation of proteolysis 20.0000 7 yes
GO:0051130 positive regulation of cellular component organization 20.0000 5 yes
GO:0051336 regulation of hydrolase activity 20.0000 4 yes
GO:0051345 positive regulation of hydrolase activity 20.0000 5 yes
GO:0141124 intracellular signaling cassette 15.0000 4 yes
GO:0070647 protein modification by small protein conjugation or removal 10.0000 6 yes
GO:1900225 regulation of NLRP3 inflammasome complex assembly 10.0000 6 yes
GO:2000116 regulation of cysteine-type endopeptidase activity 10.0000 7 yes
GO:0007264 small GTPase-mediated signal transduction 10.0000 5 yes
GO:0007265 Ras protein signal transduction 10.0000 6 yes
GO:0036211 protein modification process 10.0000 4 yes
GO:0043412 macromolecule modification 10.0000 4 yes
GO:0043687 post-translational protein modification 10.0000 5 yes
GO:0052547 regulation of peptidase activity 10.0000 5 yes
GO:0052548 regulation of endopeptidase activity 10.0000 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
HS90B_HUMAN [view entry] [view interactions] Low throughput yes yes
HS90A_HUMAN [view entry] [view interactions] Low throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71B_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71A_HUMAN [view entry] [view interactions] Low throughput yes yes
NLRP3_HUMAN [view interactions] Low throughput no no
ASC_HUMAN [view interactions] Low throughput no no
XRCC6_HUMAN [view interactions] Low throughput no yes
CPT1A_HUMAN [view entry] [view interactions] Low throughput yes yes
ZHX2_HUMAN [view interactions] Low throughput no yes
ACE2_HUMAN [view interactions] Low throughput no no
MPRI_HUMAN [view interactions] High throughput no yes
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
DYHC2_HUMAN [view interactions] High throughput no yes
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
SRPRB_HUMAN [view entry] [view interactions] High throughput yes no
ABCD3_HUMAN [view entry] [view interactions] High throughput yes yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
AMRA1_HUMAN [view interactions] High throughput no yes
AAAT_HUMAN [view interactions] High throughput no no
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
C1TM_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
NU205_HUMAN [view interactions] High throughput no no
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
UMPS_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
S2513_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
ACADM_HUMAN [view interactions] High throughput no yes
LUC7L_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes