CAN1_HUMAN
Evidence for PS localization
Functions
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed, PubMed). Proteolytically cleaves CTBP1 at Asn-375, Gly-387 and His-409 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CAN1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 27.1186 | 4 | no |
| GO:0019900 | kinase binding | 27.1186 | 4 | no |
| GO:0019901 | protein kinase binding | 27.1186 | 5 | no |
| GO:0017076 | purine nucleotide binding | 23.7288 | 4 | no |
| GO:0046872 | metal ion binding | 22.0339 | 4 | yes |
| GO:0003779 | actin binding | 22.0339 | 4 | no |
| GO:0045296 | cadherin binding | 22.0339 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0339 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.0339 | 4 | no |
| GO:0005509 | calcium ion binding | 13.5593 | 5 | yes |
| GO:0004175 | endopeptidase activity | 5.0847 | 4 | yes |
| GO:0004197 | cysteine-type endopeptidase activity | 3.3898 | 5 | yes |
| GO:0008234 | cysteine-type peptidase activity | 3.3898 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CAN1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 66.1017 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 66.1017 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 59.3220 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 57.6271 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 57.6271 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 55.9322 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.5424 | 4 | yes |
| GO:0006996 | organelle organization | 50.8475 | 4 | no |
| GO:0010468 | regulation of gene expression | 47.4576 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 47.4576 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 45.7627 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.7627 | 4 | no |
| GO:0010941 | regulation of cell death | 44.0678 | 4 | no |
| GO:0022607 | cellular component assembly | 44.0678 | 4 | no |
| GO:0009966 | regulation of signal transduction | 44.0678 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 44.0678 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 44.0678 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 44.0678 | 5 | no |
| GO:0051049 | regulation of transport | 42.3729 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.3729 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 42.3729 | 5 | no |
| GO:0071310 | cellular response to organic substance | 40.6780 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 40.6780 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 40.6780 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 40.6780 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 40.6780 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 38.9831 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 37.2881 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 37.2881 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 35.5932 | 4 | no |
| GO:0009894 | regulation of catabolic process | 35.5932 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 35.5932 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 35.5932 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 35.5932 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 33.8983 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 33.8983 | 6 | no |
| GO:0007010 | cytoskeleton organization | 33.8983 | 5 | no |
| GO:0051050 | positive regulation of transport | 32.2034 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 32.2034 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.2034 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 32.2034 | 5 | no |
| GO:0023056 | positive regulation of signaling | 32.2034 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 32.2034 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 32.2034 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.5085 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 30.5085 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 28.8136 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 28.8136 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.8136 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.8136 | 5 | no |
| GO:0051336 | regulation of hydrolase activity | 28.8136 | 4 | no |
| GO:0060341 | regulation of cellular localization | 28.8136 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.8136 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 28.8136 | 4 | no |
| GO:0031399 | regulation of protein modification process | 27.1186 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 27.1186 | 5 | no |
| GO:0032880 | regulation of protein localization | 27.1186 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 27.1186 | 7 | no |
| GO:0060548 | negative regulation of cell death | 27.1186 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 27.1186 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 27.1186 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.1186 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 27.1186 | 4 | no |
| GO:0030334 | regulation of cell migration | 25.4237 | 5 | no |
| GO:0043412 | macromolecule modification | 25.4237 | 4 | no |
| GO:2000145 | regulation of cell motility | 25.4237 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.4237 | 5 | no |
| GO:0030030 | cell projection organization | 25.4237 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.4237 | 4 | no |
| GO:0043269 | regulation of ion transport | 25.4237 | 5 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 25.4237 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.4237 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 25.4237 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.4237 | 6 | no |
| GO:1901214 | regulation of neuron death | 23.7288 | 5 | no |
| GO:0008104 | protein localization | 23.7288 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 23.7288 | 6 | no |
| GO:0030162 | regulation of proteolysis | 23.7288 | 6 | no |
| GO:0036211 | protein modification process | 23.7288 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 23.7288 | 8 | no |
| GO:0043066 | negative regulation of apoptotic process | 23.7288 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 23.7288 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 23.7288 | 7 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.7288 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.7288 | 6 | no |
| GO:0010942 | positive regulation of cell death | 23.7288 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 23.7288 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 23.7288 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 23.7288 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.7288 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.7288 | 6 | no |
| GO:0010629 | negative regulation of gene expression | 23.7288 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 23.7288 | 6 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.0339 | 4 | no |
| GO:0010959 | regulation of metal ion transport | 22.0339 | 6 | no |
| GO:0051093 | negative regulation of developmental process | 22.0339 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 22.0339 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.0339 | 7 | no |
| GO:0051338 | regulation of transferase activity | 22.0339 | 4 | no |
| GO:0051345 | positive regulation of hydrolase activity | 22.0339 | 5 | no |
| GO:0080134 | regulation of response to stress | 22.0339 | 4 | no |
| GO:0034330 | cell junction organization | 22.0339 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 22.0339 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 22.0339 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 22.0339 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 22.0339 | 6 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 20.3390 | 6 | no |
| GO:0071417 | cellular response to organonitrogen compound | 20.3390 | 4 | no |
| GO:1901699 | cellular response to nitrogen compound | 20.3390 | 4 | no |
| GO:0014070 | response to organic cyclic compound | 20.3390 | 4 | no |
| GO:0045596 | negative regulation of cell differentiation | 20.3390 | 5 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 20.3390 | 8 | no |
| GO:0016310 | phosphorylation | 20.3390 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 20.3390 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 20.3390 | 7 | no |
| GO:0033993 | response to lipid | 20.3390 | 4 | no |
| GO:0045597 | positive regulation of cell differentiation | 20.3390 | 5 | no |
| GO:0045862 | positive regulation of proteolysis | 20.3390 | 7 | no |
| GO:0060284 | regulation of cell development | 20.3390 | 5 | no |
| GO:1903829 | positive regulation of protein localization | 20.3390 | 5 | no |
| GO:0010506 | regulation of autophagy | 20.3390 | 6 | yes |
| GO:0034762 | regulation of transmembrane transport | 20.3390 | 4 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 20.3390 | 6 | no |
| GO:0034765 | regulation of ion transmembrane transport | 18.6441 | 5 | yes |
| GO:1904062 | regulation of cation transmembrane transport | 18.6441 | 6 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 16.9492 | 5 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 13.5593 | 4 | yes |
| GO:0016241 | regulation of macroautophagy | 11.8644 | 7 | yes |
| GO:0032412 | regulation of ion transmembrane transporter activity | 11.8644 | 5 | yes |
| GO:0009057 | macromolecule catabolic process | 10.1695 | 4 | yes |
| GO:2001257 | regulation of cation channel activity | 10.1695 | 6 | yes |
| GO:0006508 | proteolysis | 8.4746 | 4 | yes |
| GO:0099601 | regulation of neurotransmitter receptor activity | 5.0847 | 4 | yes |
| GO:0032801 | receptor catabolic process | 3.3898 | 4 | yes |
| GO:0043112 | receptor metabolic process | 3.3898 | 4 | yes |
| GO:2000310 | regulation of NMDA receptor activity | 3.3898 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in CAN1_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 3.3898 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.3898 | 5 | no |
| DOID:114 | heart disease | 3.3898 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 3.3898 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ICAL_HUMAN | [view interactions] | Low throughput | no | yes |
| CPNS1_HUMAN | [view interactions] | Low throughput | no | yes |
| CFTR_HUMAN | [view interactions] | Low throughput | no | no |
| PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
| TIRAP_HUMAN | [view interactions] | Low throughput | no | no |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PSN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FANCA_HUMAN | [view interactions] | Low throughput | no | no |
| FANCG_HUMAN | [view interactions] | Low throughput | no | yes |
| FANCC_HUMAN | [view interactions] | Low throughput | no | yes |
| PALB2_HUMAN | [view interactions] | Low throughput | no | yes |
| GAS2_HUMAN | [view interactions] | Low throughput | no | no |
| RAD21_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| NMT1_HUMAN | [view interactions] | Low throughput | no | yes |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| CPEB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTN5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATG5_HUMAN | [view interactions] | Low throughput | no | no |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLC4G_HUMAN | [view interactions] | High throughput | no | no |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| SYCM_HUMAN | [view interactions] | High throughput | no | yes |
| DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
| COG1_HUMAN | [view interactions] | High throughput | no | yes |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| TB22B_HUMAN | [view interactions] | High throughput | no | no |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| ZIC1_HUMAN | [view interactions] | High throughput | no | yes |
| CPNS2_HUMAN | [view interactions] | High throughput | no | no |
| C99L2_HUMAN | [view interactions] | High throughput | no | yes |
| RP9_HUMAN | [view interactions] | High throughput | no | yes |
| AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIPC_HUMAN | [view interactions] | High throughput | no | yes |
| FNTB_HUMAN | [view interactions] | High throughput | no | no |
| NEST_HUMAN | [view interactions] | High throughput | no | no |
| CAN2_HUMAN | [view interactions] | High throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAN8_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE164_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3BG_HUMAN | [view interactions] | High throughput | no | no |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| TINAL_HUMAN | [view interactions] | High throughput | no | no |
| CREG1_HUMAN | [view interactions] | High throughput | no | no |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLIT3_HUMAN | [view interactions] | High throughput | no | yes |
| ALAT1_HUMAN | [view interactions] | High throughput | no | no |
| CATC_HUMAN | [view interactions] | High throughput | no | yes |
| PTGDS_HUMAN | [view interactions] | High throughput | no | yes |
| TLE5_HUMAN | [view interactions] | High throughput | no | no |
| NF2L1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CO1A1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| KNG1_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR17_HUMAN | [view interactions] | High throughput | no | yes |
| FXL12_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| CD109_HUMAN | [view interactions] | High throughput | no | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FNTA_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
| TGFB1_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIRC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| OR2A4_HUMAN | [view interactions] | High throughput | no | no |
| ZC3H4_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| SAFB1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR33_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| S22A1_HUMAN | [view interactions] | High throughput | no | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP1_HUMAN | [view interactions] | High throughput | no | no |
| BCCIP_HUMAN | [view interactions] | High throughput | no | no |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNS_HUMAN | [view interactions] | High throughput | no | yes |
| LDH6B_HUMAN | [view interactions] | High throughput | no | no |
| PEPD_HUMAN | [view interactions] | High throughput | no | yes |
| PUR4_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| P4R3B_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASP7_HUMAN | [view interactions] | High throughput | no | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBP2_HUMAN | [view interactions] | High throughput | no | yes |
| PSF2_HUMAN | [view interactions] | High throughput | no | no |
| PSF3_HUMAN | [view interactions] | High throughput | no | yes |
| AGAL_HUMAN | [view interactions] | High throughput | no | yes |
| GLSK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MVD1_HUMAN | [view interactions] | High throughput | no | yes |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MA2A1_HUMAN | [view interactions] | High throughput | no | no |
| EIF2A_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| NIT1_HUMAN | [view interactions] | High throughput | no | yes |
| MTREX_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCP60_HUMAN | [view interactions] | High throughput | no | yes |
| BID_HUMAN | [view interactions] | High throughput | no | no |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MESD_HUMAN | [view interactions] | High throughput | no | yes |
| SDF2_HUMAN | [view interactions] | High throughput | no | no |
| OS9_HUMAN | [view interactions] | High throughput | no | yes |
| UGGG1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| BAK_HUMAN | [view interactions] | Computational | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| NOLC1_HUMAN | [view interactions] | Computational | no | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CSK_HUMAN | [view interactions] | Computational | no | yes |
| FILA_HUMAN | [view interactions] | Computational | no | no |
| PAXI_HUMAN | [view interactions] | Computational | no | yes |
| TENS1_HUMAN | [view interactions] | Computational | no | no |
| ITA1_HUMAN | [view interactions] | Computational | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| IL1A_HUMAN | [view interactions] | Computational | no | no |
| ACTN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CD5R1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CRKL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TLN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ACTS_HUMAN | [view interactions] | Computational | no | no |
| BAX_HUMAN | [view interactions] | Computational | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| CDK5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ZYX_HUMAN | [view interactions] | Computational | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |