ACTN2_HUMAN
Evidence for PS localization
Functions
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 9 | Gln | Arg | Cardiomyopathy,dilated,1AA,withorwithoutleftventricularnon-compaction(CMD1AA) | - |
| 119 | Ala | Thr | Cardiomyopathy,dilated,1AA,withorwithoutleftventricularnon-compaction(CMD1AA) | - |
| 119 | Ala | Thr | Cardiomyopathy,familialhypertrophic,23,withorwithoutleftventricularnon-compaction(CMH23) | - |
| 495 | Thr | Met | Cardiomyopathy,familialhypertrophic,23,withorwithoutleftventricularnon-compaction(CMH23) | - |
| 583 | Glu | Ala | Cardiomyopathy,familialhypertrophic,23,withorwithoutleftventricularnon-compaction(CMH23) | - |
| 628 | Glu | Gly | Cardiomyopathy,familialhypertrophic,23,withorwithoutleftventricularnon-compaction(CMH23) | - |
| 228 | Met | Thr | Cardiomyopathy,familialhypertrophic,23,withorwithoutleftventricularnon-compaction(CMH23) | - |
| 487 | Cys | Arg | Myopathy,distal,6,adultonset,autosomaldominant(MPD6) | - |
| 727 | Leu | Arg | Congenitalmyopathy8(CMYP8) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ACTN2_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 39.3939 | 4 | yes |
| GO:0046872 | metal ion binding | 39.3939 | 5 | yes |
| GO:0043168 | anion binding | 30.3030 | 4 | yes |
| GO:0019900 | kinase binding | 25.7576 | 4 | no |
| GO:0042803 | protein homodimerization activity | 22.7273 | 4 | no |
| GO:0003779 | actin binding | 22.7273 | 4 | yes |
| GO:0005509 | calcium ion binding | 15.1515 | 6 | yes |
| GO:0035091 | phosphatidylinositol binding | 7.5758 | 4 | yes |
| GO:0030374 | nuclear receptor coactivator activity | 6.0606 | 4 | yes |
| GO:0031432 | titin binding | 4.5455 | 4 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 4.5455 | 5 | yes |
| GO:1902936 | phosphatidylinositol bisphosphate binding | 4.5455 | 6 | yes |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | 4.5455 | 5 | yes |
| GO:0030274 | LIM domain binding | 3.0303 | 4 | yes |
| GO:0051373 | FATZ binding | 3.0303 | 4 | yes |
| GO:0070080 | titin Z domain binding | 3.0303 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACTN2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 59.0909 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 48.4848 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 46.9697 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.4545 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 42.4242 | 4 | no |
| GO:0010646 | regulation of cell communication | 42.4242 | 4 | no |
| GO:0006996 | organelle organization | 39.3939 | 4 | yes |
| GO:0008104 | protein localization | 39.3939 | 4 | yes |
| GO:0051049 | regulation of transport | 37.8788 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 36.3636 | 4 | no |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
| GO:0034762 | regulation of transmembrane transport | 30.3030 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 30.3030 | 4 | no |
| GO:0010468 | regulation of gene expression | 30.3030 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.3030 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.3030 | 5 | no |
| GO:0043269 | regulation of monoatomic ion transport | 27.2727 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:0007010 | cytoskeleton organization | 25.7576 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 25.7576 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 25.7576 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 25.7576 | 5 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 24.2424 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 24.2424 | 5 | no |
| GO:0010959 | regulation of metal ion transport | 22.7273 | 6 | yes |
| GO:0051050 | positive regulation of transport | 22.7273 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.7273 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.7273 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 22.7273 | 5 | no |
| GO:0030030 | cell projection organization | 21.2121 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 21.2121 | 4 | yes |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 21.2121 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 21.2121 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.2121 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.2121 | 4 | no |
| GO:0022898 | regulation of transmembrane transporter activity | 19.6970 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 19.6970 | 5 | yes |
| GO:0034330 | cell junction organization | 19.6970 | 4 | yes |
| GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 18.1818 | 5 | yes |
| GO:0032880 | regulation of protein localization | 18.1818 | 5 | yes |
| GO:0072657 | protein localization to membrane | 18.1818 | 4 | yes |
| GO:0032970 | regulation of actin filament-based process | 15.1515 | 4 | yes |
| GO:0043270 | positive regulation of monoatomic ion transport | 15.1515 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 15.1515 | 5 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 13.6364 | 6 | yes |
| GO:1990778 | protein localization to cell periphery | 13.6364 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 12.1212 | 6 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 12.1212 | 5 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 12.1212 | 5 | yes |
| GO:0110053 | regulation of actin filament organization | 12.1212 | 6 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 12.1212 | 5 | yes |
| GO:0034329 | cell junction assembly | 10.6061 | 5 | yes |
| GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 10.6061 | 6 | yes |
| GO:0051051 | negative regulation of transport | 10.6061 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 10.6061 | 4 | yes |
| GO:0032411 | positive regulation of transporter activity | 9.0909 | 4 | yes |
| GO:0032414 | positive regulation of ion transmembrane transporter activity | 9.0909 | 5 | yes |
| GO:0032535 | regulation of cellular component size | 9.0909 | 4 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 9.0909 | 7 | yes |
| GO:0055001 | muscle cell development | 9.0909 | 4 | yes |
| GO:0072659 | protein localization to plasma membrane | 9.0909 | 5 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 9.0909 | 6 | yes |
| GO:1904064 | positive regulation of cation transmembrane transport | 9.0909 | 7 | yes |
| GO:0034763 | negative regulation of transmembrane transport | 7.5758 | 5 | yes |
| GO:0034766 | negative regulation of monoatomic ion transmembrane transport | 7.5758 | 6 | yes |
| GO:0043266 | regulation of potassium ion transport | 7.5758 | 7 | yes |
| GO:0043271 | negative regulation of monoatomic ion transport | 7.5758 | 5 | yes |
| GO:1901379 | regulation of potassium ion transmembrane transport | 7.5758 | 7 | yes |
| GO:2001257 | regulation of cation channel activity | 7.5758 | 6 | yes |
| GO:0007044 | cell-substrate junction assembly | 6.0606 | 6 | yes |
| GO:0008064 | regulation of actin polymerization or depolymerization | 6.0606 | 6 | yes |
| GO:0030031 | cell projection assembly | 6.0606 | 5 | yes |
| GO:0030832 | regulation of actin filament length | 6.0606 | 5 | yes |
| GO:0031032 | actomyosin structure organization | 6.0606 | 4 | yes |
| GO:0032410 | negative regulation of transporter activity | 6.0606 | 4 | yes |
| GO:0032413 | negative regulation of ion transmembrane transporter activity | 6.0606 | 5 | yes |
| GO:0045214 | sarcomere organization | 6.0606 | 5 | yes |
| GO:0048041 | focal adhesion assembly | 6.0606 | 7 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 6.0606 | 6 | yes |
| GO:0150115 | cell-substrate junction organization | 6.0606 | 5 | yes |
| GO:1901016 | regulation of potassium ion transmembrane transporter activity | 6.0606 | 6 | yes |
| GO:1904063 | negative regulation of cation transmembrane transport | 6.0606 | 7 | yes |
| GO:0038166 | angiotensin-activated signaling pathway | 4.5455 | 4 | yes |
| GO:0043268 | positive regulation of potassium ion transport | 4.5455 | 6 | yes |
| GO:0055006 | cardiac cell development | 4.5455 | 4 | yes |
| GO:0055013 | cardiac muscle cell development | 4.5455 | 5 | yes |
| GO:1903828 | negative regulation of protein localization | 4.5455 | 5 | yes |
| GO:2001259 | positive regulation of cation channel activity | 4.5455 | 6 | yes |
| GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | 3.0303 | 4 | yes |
| GO:0030035 | microspike assembly | 3.0303 | 7 | yes |
| GO:0030834 | regulation of actin filament depolymerization | 3.0303 | 7 | yes |
| GO:0030836 | positive regulation of actin filament depolymerization | 3.0303 | 7 | yes |
| GO:0032386 | regulation of intracellular transport | 3.0303 | 5 | yes |
| GO:0032388 | positive regulation of intracellular transport | 3.0303 | 5 | yes |
| GO:0043243 | positive regulation of protein-containing complex disassembly | 3.0303 | 6 | yes |
| GO:0043244 | regulation of protein-containing complex disassembly | 3.0303 | 5 | yes |
| GO:0043267 | negative regulation of potassium ion transport | 3.0303 | 6 | yes |
| GO:0051695 | actin filament uncapping | 3.0303 | 8 | yes |
| GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway | 3.0303 | 5 | yes |
| GO:1901017 | negative regulation of potassium ion transmembrane transporter activity | 3.0303 | 6 | yes |
| GO:1901018 | positive regulation of potassium ion transmembrane transporter activity | 3.0303 | 6 | yes |
| GO:1901380 | negative regulation of potassium ion transmembrane transport | 3.0303 | 7 | yes |
| GO:1901381 | positive regulation of potassium ion transmembrane transport | 3.0303 | 7 | yes |
| GO:1901879 | regulation of protein depolymerization | 3.0303 | 6 | yes |
| GO:1901881 | positive regulation of protein depolymerization | 3.0303 | 7 | yes |
| GO:2000008 | regulation of protein localization to cell surface | 3.0303 | 6 | yes |
| GO:2000009 | negative regulation of protein localization to cell surface | 3.0303 | 6 | yes |
| GO:2001135 | regulation of endocytic recycling | 3.0303 | 5 | yes |
| GO:2001137 | positive regulation of endocytic recycling | 3.0303 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KCNA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNA5_HUMAN | [view interactions] | Low throughput | no | no |
| ADA12_HUMAN | [view interactions] | Low throughput | no | no |
| LRP12_HUMAN | [view interactions] | Low throughput | no | yes |
| MYOZ1_HUMAN | [view interactions] | Low throughput | no | no |
| ANGI_HUMAN | [view interactions] | Low throughput | no | no |
| TITIN_HUMAN | [view interactions] | Low throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CAC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FXL22_HUMAN | [view interactions] | Low throughput | no | no |
| LDB3_HUMAN | [view interactions] | Low throughput | no | no |
| PDLI1_HUMAN | [view interactions] | Low throughput | no | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSRP3_HUMAN | [view interactions] | Low throughput | no | no |
| LRRC7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NRAP_HUMAN | [view interactions] | Low throughput | no | no |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTA_HUMAN | [view interactions] | Low throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYPN_HUMAN | [view interactions] | Low throughput | no | no |
| RAVR1_HUMAN | [view interactions] | Low throughput | no | no |
| FBX32_HUMAN | [view interactions] | Low throughput | no | no |
| AA2AR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ST7_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CDC73_HUMAN | [view interactions] | Low throughput | no | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAPSN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TENN_HUMAN | [view interactions] | Low throughput | no | no |
| SYNP2_HUMAN | [view interactions] | Low throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| NOS3_HUMAN | [view interactions] | High throughput | no | no |
| ATX7_HUMAN | [view interactions] | High throughput | no | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| DUX1_HUMAN | [view interactions] | High throughput | no | no |
| ALMS1_HUMAN | [view interactions] | High throughput | no | no |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2B2E_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN446_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| MOS_HUMAN | [view interactions] | High throughput | no | no |
| SAXO1_HUMAN | [view interactions] | High throughput | no | no |
| SP100_HUMAN | [view interactions] | High throughput | no | no |
| PDLI3_HUMAN | [view interactions] | High throughput | no | no |
| MYOZ2_HUMAN | [view interactions] | High throughput | no | no |
| RTP5_HUMAN | [view interactions] | High throughput | no | yes |
| BRM1L_HUMAN | [view interactions] | High throughput | no | no |
| MILK2_HUMAN | [view interactions] | High throughput | no | no |
| MYOTI_HUMAN | [view interactions] | High throughput | no | no |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMA1B_HUMAN | [view interactions] | High throughput | no | no |
| 5HT1B_HUMAN | [view interactions] | High throughput | no | no |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| RPP14_HUMAN | [view interactions] | High throughput | no | no |
| CNNM3_HUMAN | [view interactions] | High throughput | no | yes |
| NKAP1_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| FA50B_HUMAN | [view interactions] | High throughput | no | yes |
| KATL2_HUMAN | [view interactions] | High throughput | no | yes |
| DYT2B_HUMAN | [view interactions] | High throughput | no | no |
| GOGA7_HUMAN | [view interactions] | High throughput | no | yes |
| RM10_HUMAN | [view interactions] | High throughput | no | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| AT5G1_HUMAN | [view interactions] | High throughput | no | no |
| ANGL7_HUMAN | [view interactions] | High throughput | no | no |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRADD_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| GSTT1_HUMAN | [view interactions] | High throughput | no | no |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| RABP2_HUMAN | [view interactions] | High throughput | no | no |
| CD27_HUMAN | [view interactions] | High throughput | no | no |
| SP17_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARX_HUMAN | [view interactions] | High throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMCA2_HUMAN | [view interactions] | High throughput | no | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASH2L_HUMAN | [view interactions] | High throughput | no | yes |
| DYSF_HUMAN | [view interactions] | High throughput | no | no |
| MAST2_HUMAN | [view interactions] | High throughput | no | yes |
| MYPC2_HUMAN | [view interactions] | High throughput | no | no |
| MYOM2_HUMAN | [view interactions] | High throughput | no | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| KAT2B_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPR_HUMAN | [view interactions] | High throughput | no | yes |
| NR1I2_HUMAN | [view interactions] | High throughput | no | no |
| CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNDH2_HUMAN | [view interactions] | High throughput | no | no |
| ZC21C_HUMAN | [view interactions] | High throughput | no | yes |
| SYP2L_HUMAN | [view interactions] | High throughput | no | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| NFIX_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH1_HUMAN | [view interactions] | High throughput | no | no |
| MYH2_HUMAN | [view interactions] | High throughput | no | yes |
| MYH3_HUMAN | [view interactions] | High throughput | no | no |
| MYH4_HUMAN | [view interactions] | High throughput | no | no |
| MYH6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH7_HUMAN | [view interactions] | High throughput | no | no |
| MYH8_HUMAN | [view interactions] | High throughput | no | no |
| PSB5_HUMAN | [view interactions] | High throughput | no | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNNI1_HUMAN | [view interactions] | High throughput | no | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| FGF12_HUMAN | [view interactions] | High throughput | no | no |
| PGAM2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |