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RYR2_HUMAN

Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development. [View more on UniProt]

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Download full PS network for entry.
Position Amino acid Mutation Disease Overlap with binding region
433 Leu Pro Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2246 Ser Leu Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2328 Pro Ser Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2386 Asn Ile Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2474 Arg Ser Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4104 Asn Lys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4201 Gln Arg Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4497 Arg Cys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4653 Val Phe Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2306 Val Ile Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4902 Pro Leu Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4959 Arg Gln Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
164 Pro Ser Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
176 Arg Gln Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
414 Arg Leu Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
419 Ile Phe Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
420 Arg Trp Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2311 Glu Asp Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2387 Ala Pro Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2392 Tyr Cys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2403 Ala Thr Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
2504 Thr Met Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
3778 Leu Phe Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
3946 Gly Ser Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4097 Asn Ser Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4146 Glu Lys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4158 Thr Pro Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4499 Phe Cys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4504 Met Ile Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4510 Ala Thr Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4607 Ala Pro Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4671 Gly Arg Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4771 Val Ile Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4848 Ile Val Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4860 Ala Gly Ventriculararrhythmiasduetocardiacryanodinereceptorcalciumreleasedeficiencysyndrome(VACRDS) -
4867 Ile Met Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4880 Val Ala Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4895 Asn Asp Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4950 Glu Lys Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
3800 Cys Phe Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4124 Ser Thr Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4159 Gln Pro Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
4556 Ala Thr Ventriculartachycardia,catecholaminergicpolymorphic,1,withorwithoutatrialdysfunctionand/ordilatedcardiomyopathy(CPVT1) -
3774 Gln Leu Ventriculararrhythmiasduetocardiacryanodinereceptorcalciumreleasedeficiencysyndrome(VACRDS) -
4196 Thr Ile Ventriculararrhythmiasduetocardiacryanodinereceptorcalciumreleasedeficiencysyndrome(VACRDS) -
4646 Asp Ala Ventriculararrhythmiasduetocardiacryanodinereceptorcalciumreleasedeficiencysyndrome(VACRDS) -
4938 Ser Phe Ventriculararrhythmiasduetocardiacryanodinereceptorcalciumreleasedeficiencysyndrome(VACRDS) -

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RYR2_HUMAN
GO:0043169 cation binding 34.8485 4 yes
GO:0046872 metal ion binding 34.8485 5 yes
GO:0043168 anion binding 31.8182 4 yes
GO:0000166 nucleotide binding 22.7273 4 no
GO:0019900 kinase binding 21.2121 4 yes
GO:0019901 protein kinase binding 21.2121 5 yes
GO:0005509 calcium ion binding 12.1212 6 yes
GO:0015267 channel activity 12.1212 4 yes
GO:0005216 monoatomic ion channel activity 10.6061 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 10.6061 4 yes
GO:0005261 monoatomic cation channel activity 9.0909 5 yes
GO:0005262 calcium channel activity 9.0909 6 yes
GO:0008324 monoatomic cation transmembrane transporter activity 9.0909 4 yes
GO:0015085 calcium ion transmembrane transporter activity 9.0909 6 yes
GO:0022836 gated channel activity 9.0909 5 yes
GO:0046873 metal ion transmembrane transporter activity 9.0909 5 yes
GO:0015276 ligand-gated monoatomic ion channel activity 6.0606 5 yes
GO:0022834 ligand-gated channel activity 6.0606 6 yes
GO:0034236 protein kinase A catalytic subunit binding 6.0606 4 yes
GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4.5455 6 yes
GO:0015278 intracellularly gated calcium channel activity 4.5455 7 yes
GO:0034237 protein kinase A regulatory subunit binding 4.5455 4 yes
GO:0099094 ligand-gated monoatomic cation channel activity 4.5455 6 yes
GO:0099604 ligand-gated calcium channel activity 4.5455 7 yes
GO:0005219 ryanodine-sensitive calcium-release channel activity 3.0303 9 yes
GO:0048763 calcium-induced calcium release activity 3.0303 8 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RYR2_HUMAN
GO:0048522 positive regulation of cellular process 57.5758 4 yes
GO:0048523 negative regulation of cellular process 51.5152 4 yes
GO:0031323 regulation of cellular metabolic process 46.9697 4 no
GO:0010646 regulation of cell communication 46.9697 4 yes
GO:0051049 regulation of transport 45.4545 4 yes
GO:0060255 regulation of macromolecule metabolic process 43.9394 4 no
GO:0080090 regulation of primary metabolic process 40.9091 4 no
GO:0051128 regulation of cellular component organization 34.8485 4 no
GO:0022607 cellular component assembly 34.8485 4 no
GO:0009889 regulation of biosynthetic process 31.8182 4 no
GO:0051050 positive regulation of transport 31.8182 4 yes
GO:0031326 regulation of cellular biosynthetic process 30.3030 5 no
GO:0009966 regulation of signal transduction 30.3030 4 no
GO:0008104 protein localization 30.3030 4 yes
GO:0006996 organelle organization 28.7879 4 no
GO:0010556 regulation of macromolecule biosynthetic process 28.7879 5 no
GO:0044057 regulation of system process 28.7879 4 yes
GO:0009893 positive regulation of metabolic process 27.2727 4 no
GO:0009892 negative regulation of metabolic process 27.2727 4 no
GO:0051246 regulation of protein metabolic process 27.2727 5 no
GO:0060341 regulation of cellular localization 27.2727 4 no
GO:0034762 regulation of transmembrane transport 27.2727 4 yes
GO:0043269 regulation of monoatomic ion transport 27.2727 5 yes
GO:1903522 regulation of blood circulation 25.7576 5 yes
GO:0031325 positive regulation of cellular metabolic process 25.7576 5 no
GO:0043933 protein-containing complex organization 25.7576 4 no
GO:0010959 regulation of metal ion transport 25.7576 6 yes
GO:0034765 regulation of monoatomic ion transmembrane transport 25.7576 5 yes
GO:1904062 regulation of monoatomic cation transmembrane transport 24.2424 6 yes
GO:0023056 positive regulation of signaling 24.2424 4 no
GO:0031324 negative regulation of cellular metabolic process 24.2424 5 no
GO:0010468 regulation of gene expression 24.2424 6 no
GO:0010605 negative regulation of macromolecule metabolic process 24.2424 5 no
GO:0010647 positive regulation of cell communication 22.7273 5 no
GO:0048584 positive regulation of response to stimulus 22.7273 4 no
GO:0010648 negative regulation of cell communication 22.7273 5 no
GO:0023057 negative regulation of signaling 22.7273 4 no
GO:0032880 regulation of protein localization 22.7273 5 no
GO:0042981 regulation of apoptotic process 22.7273 5 no
GO:0043067 regulation of programmed cell death 22.7273 4 no
GO:0008016 regulation of heart contraction 22.7273 6 yes
GO:0036211 protein modification process 21.2121 4 no
GO:0043412 macromolecule modification 21.2121 4 no
GO:0006796 phosphate-containing compound metabolic process 21.2121 4 no
GO:1902531 regulation of intracellular signal transduction 21.2121 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.2121 5 no
GO:0051924 regulation of calcium ion transport 21.2121 7 yes
GO:0141124 intracellular signaling cassette 19.6970 4 yes
GO:0022898 regulation of transmembrane transporter activity 19.6970 4 yes
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 19.6970 5 yes
GO:0051240 positive regulation of multicellular organismal process 19.6970 4 yes
GO:0071310 cellular response to organic substance 19.6970 4 yes
GO:1903169 regulation of calcium ion transmembrane transport 18.1818 7 yes
GO:0010038 response to metal ion 18.1818 4 yes
GO:0006937 regulation of muscle contraction 16.6667 6 yes
GO:0006942 regulation of striated muscle contraction 16.6667 7 yes
GO:0051282 regulation of sequestering of calcium ion 16.6667 4 yes
GO:0055117 regulation of cardiac muscle contraction 16.6667 7 yes
GO:0090257 regulation of muscle system process 16.6667 5 yes
GO:0006811 monoatomic ion transport 15.1515 4 yes
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 15.1515 6 yes
GO:0043270 positive regulation of monoatomic ion transport 15.1515 5 yes
GO:0051279 regulation of release of sequestered calcium ion into cytosol 15.1515 5 yes
GO:0051592 response to calcium ion 15.1515 5 yes
GO:1901019 regulation of calcium ion transmembrane transporter activity 13.6364 6 yes
GO:0006812 monoatomic cation transport 13.6364 5 yes
GO:0006816 calcium ion transport 13.6364 7 yes
GO:0010243 response to organonitrogen compound 13.6364 4 yes
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 13.6364 7 yes
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 13.6364 6 yes
GO:0019722 calcium-mediated signaling 13.6364 5 yes
GO:0030001 metal ion transport 13.6364 6 yes
GO:0032970 regulation of actin filament-based process 13.6364 4 yes
GO:0034764 positive regulation of transmembrane transport 13.6364 5 yes
GO:1901699 cellular response to nitrogen compound 12.1212 4 yes
GO:0001508 action potential 12.1212 4 yes
GO:0006873 intracellular monoatomic ion homeostasis 12.1212 4 yes
GO:0030003 intracellular monoatomic cation homeostasis 12.1212 5 yes
GO:0034767 positive regulation of monoatomic ion transmembrane transport 12.1212 6 yes
GO:0051928 positive regulation of calcium ion transport 12.1212 6 yes
GO:0055080 monoatomic cation homeostasis 12.1212 4 yes
GO:0071417 cellular response to organonitrogen compound 12.1212 4 yes
GO:0098901 regulation of cardiac muscle cell action potential 10.6061 4 yes
GO:1904064 positive regulation of cation transmembrane transport 10.6061 7 yes
GO:0006874 intracellular calcium ion homeostasis 10.6061 5 yes
GO:0014070 response to organic cyclic compound 10.6061 4 yes
GO:0032411 positive regulation of transporter activity 10.6061 4 yes
GO:0032414 positive regulation of ion transmembrane transporter activity 10.6061 5 yes
GO:0051284 positive regulation of sequestering of calcium ion 10.6061 5 yes
GO:0055074 calcium ion homeostasis 10.6061 4 yes
GO:1904427 positive regulation of calcium ion transmembrane transport 9.0909 7 yes
GO:0002009 morphogenesis of an epithelium 9.0909 4 yes
GO:0006915 apoptotic process 9.0909 4 yes
GO:0070588 calcium ion transmembrane transport 9.0909 5 yes
GO:0086001 cardiac muscle cell action potential 9.0909 5 yes
GO:0086002 cardiac muscle cell action potential involved in contraction 9.0909 6 yes
GO:0086064 cell communication by electrical coupling involved in cardiac conduction 9.0909 4 yes
GO:0097553 calcium ion transmembrane import into cytosol 9.0909 6 yes
GO:0098655 monoatomic cation transmembrane transport 9.0909 4 yes
GO:0098662 inorganic cation transmembrane transport 9.0909 4 yes
GO:1901021 positive regulation of calcium ion transmembrane transporter activity 7.5758 6 yes
GO:1903115 regulation of actin filament-based movement 7.5758 5 yes
GO:0005513 detection of calcium ion 7.5758 4 yes
GO:0006936 muscle contraction 7.5758 4 yes
GO:0036293 response to decreased oxygen levels 7.5758 4 yes
GO:0060562 epithelial tube morphogenesis 7.5758 4 yes
GO:0071407 cellular response to organic cyclic compound 7.5758 5 yes
GO:0086004 regulation of cardiac muscle cell contraction 7.5758 6 yes
GO:0098911 regulation of ventricular cardiac muscle cell action potential 6.0606 5 yes
GO:0003143 embryonic heart tube morphogenesis 6.0606 4 yes
GO:0033365 protein localization to organelle 6.0606 5 yes
GO:0051209 release of sequestered calcium ion into cytosol 6.0606 6 yes
GO:0051283 negative regulation of sequestering of calcium ion 6.0606 5 yes
GO:0051480 regulation of cytosolic calcium ion concentration 6.0606 6 yes
GO:1903779 regulation of cardiac conduction 4.5455 7 yes
GO:0006941 striated muscle contraction 4.5455 5 yes
GO:0043279 response to alkaloid 4.5455 5 yes
GO:0060402 calcium ion transport into cytosol 4.5455 4 yes
GO:0071312 cellular response to alkaloid 4.5455 5 yes
GO:0071872 cellular response to epinephrine stimulus 4.5455 4 yes
GO:0086005 ventricular cardiac muscle cell action potential 4.5455 7 yes
GO:0098735 positive regulation of the force of heart contraction 3.0303 4 yes
GO:0098904 regulation of AV node cell action potential 3.0303 5 yes
GO:0098907 regulation of SA node cell action potential 3.0303 5 yes
GO:0098910 regulation of atrial cardiac muscle cell action potential 3.0303 5 yes
GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 3.0303 4 yes
GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity 3.0303 5 yes
GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3.0303 7 yes
GO:1903524 positive regulation of blood circulation 3.0303 5 yes
GO:1904019 epithelial cell apoptotic process 3.0303 5 yes
GO:0003220 left ventricular cardiac muscle tissue morphogenesis 3.0303 7 yes
GO:0003300 cardiac muscle hypertrophy 3.0303 6 yes
GO:0010460 positive regulation of heart rate 3.0303 4 yes
GO:0014074 response to purine-containing compound 3.0303 5 yes
GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3.0303 8 yes
GO:0014896 muscle hypertrophy 3.0303 4 yes
GO:0014897 striated muscle hypertrophy 3.0303 5 yes
GO:0031000 response to caffeine 3.0303 6 yes
GO:0032781 positive regulation of ATP-dependent activity 3.0303 4 yes
GO:0035994 response to muscle stretch 3.0303 4 yes
GO:0045823 positive regulation of heart contraction 3.0303 6 yes
GO:0055008 cardiac muscle tissue morphogenesis 3.0303 5 yes
GO:0055010 ventricular cardiac muscle tissue morphogenesis 3.0303 6 yes
GO:0060048 cardiac muscle contraction 3.0303 6 yes
GO:0060415 muscle tissue morphogenesis 3.0303 4 yes
GO:0070296 sarcoplasmic reticulum calcium ion transport 3.0303 8 yes
GO:0070972 protein localization to endoplasmic reticulum 3.0303 6 yes
GO:0071313 cellular response to caffeine 3.0303 6 yes
GO:0071415 cellular response to purine-containing compound 3.0303 5 yes
GO:0072594 establishment of protein localization to organelle 3.0303 4 yes
GO:0072599 establishment of protein localization to endoplasmic reticulum 3.0303 5 yes
GO:0086019 cell-cell signaling involved in cardiac conduction 3.0303 4 yes
GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling 3.0303 5 yes
GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell communication 3.0303 4 yes
GO:0097050 type B pancreatic cell apoptotic process 3.0303 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
FKB1B_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
RYR2_HUMAN [view entry] [view interactions] Low throughput yes yes
RYR1_HUMAN [view interactions] Low throughput no no
SORCN_HUMAN [view entry] [view interactions] Low throughput yes yes
PLCE1_HUMAN [view interactions] Low throughput no yes
AKAP6_HUMAN [view interactions] Low throughput no no
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
SRCH_HUMAN [view interactions] Low throughput no no
PKD2_HUMAN [view interactions] Low throughput no yes
KCC2D_HUMAN [view entry] [view interactions] Low throughput yes yes
CAC1C_HUMAN [view entry] [view interactions] Low throughput yes no
FKB1A_HUMAN [view interactions] Low throughput no yes
RYR3_HUMAN [view interactions] Low throughput no no
PSN2_HUMAN [view entry] [view interactions] Low throughput yes no
RTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE2C_HUMAN [view interactions] Low throughput no yes
HOME1_HUMAN [view entry] [view interactions] Low throughput yes yes
PSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAPCG_HUMAN [view interactions] Low throughput no no
KAPCB_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNN4_HUMAN [view interactions] Low throughput no no
CAC1D_HUMAN [view entry] [view interactions] Low throughput yes yes
JPH3_HUMAN [view interactions] Low throughput no no
JPH4_HUMAN [view interactions] Low throughput no no
KAP2_HUMAN [view entry] [view interactions] Low throughput yes yes
KAP3_HUMAN [view entry] [view interactions] Low throughput yes yes
PP1A_HUMAN [view entry] [view interactions] Low throughput yes yes
PP1B_HUMAN [view entry] [view interactions] Low throughput yes yes
PP1G_HUMAN [view entry] [view interactions] Low throughput yes yes
S10A1_HUMAN [view interactions] Low throughput no yes
SMAD5_HUMAN [view interactions] High throughput no no
COPB_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB2_HUMAN [view interactions] High throughput no yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
ALBU_HUMAN [view interactions] High throughput no no
CAV3_HUMAN [view interactions] High throughput no no
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
PSA4_HUMAN [view entry] [view interactions] High throughput yes yes
SPAT7_HUMAN [view interactions] High throughput no no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
SPEG_HUMAN [view interactions] High throughput no no
COBL1_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
PSA3_HUMAN [view interactions] High throughput no no
SNTA1_HUMAN [view entry] [view interactions] High throughput yes no
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
PSA2_HUMAN [view interactions] High throughput no yes
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
MYH1_HUMAN [view interactions] High throughput no no
ODPX_HUMAN [view entry] [view interactions] High throughput yes yes
KNG1_HUMAN [view interactions] High throughput no no
HRG_HUMAN [view interactions] High throughput no no
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
CATD_HUMAN [view interactions] High throughput no yes
IRAG2_HUMAN [view interactions] High throughput no yes
AATC_HUMAN [view entry] [view interactions] High throughput yes yes
FABPH_HUMAN [view entry] [view interactions] High throughput yes no
TGM3_HUMAN [view interactions] High throughput no no
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
H33_HUMAN [view interactions] High throughput no yes
MY18B_HUMAN [view interactions] High throughput no no
MYPC3_HUMAN [view interactions] High throughput no no
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
TBB2B_HUMAN [view entry] [view interactions] High throughput yes yes
ODB2_HUMAN [view entry] [view interactions] High throughput yes yes
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
ARF1_HUMAN [view entry] [view interactions] High throughput yes yes
NONO_HUMAN [view interactions] High throughput no yes
EIF3H_HUMAN [view interactions] High throughput no yes
AINX_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
C1QC_HUMAN [view entry] [view interactions] High throughput yes yes
SPTN4_HUMAN [view entry] [view interactions] High throughput yes no
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
FIBG_HUMAN [view entry] [view interactions] High throughput yes no
FIBA_HUMAN [view interactions] High throughput no no
FIBB_HUMAN [view entry] [view interactions] High throughput yes no
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
LRC10_HUMAN [view interactions] High throughput no no
SYVC_HUMAN [view interactions] High throughput no yes
IF6_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
MDM2_HUMAN [view entry] [view interactions] High throughput yes yes
BIN1_HUMAN [view entry] [view interactions] High throughput yes yes
TERF1_HUMAN [view interactions] High throughput no no
TERF2_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
OTUD4_HUMAN [view interactions] High throughput no yes
ACTN2_HUMAN [view entry] [view interactions] High throughput yes yes
ITPR1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX4_HUMAN [view entry] [view interactions] High throughput yes yes
CPNE9_HUMAN [view interactions] High throughput no no
RASL1_HUMAN [view entry] [view interactions] High throughput yes yes
RBM20_HUMAN [view interactions] High throughput no no
MK11_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
NUP43_HUMAN [view interactions] High throughput no yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
SAR1B_HUMAN [view interactions] High throughput no yes
ARL2_HUMAN [view interactions] High throughput no yes
TRI23_HUMAN [view interactions] High throughput no yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes