Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

BIN1_HUMAN

Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (PubMed). Is a negative regulator of endocytosis . Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (PubMed). In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates . May be involved in the regulation of MYC activity and the control cell proliferation (PubMed). Has actin bundling activity and stabilizes actin filaments against depolymerization in vitro (PubMed). [View more on UniProt]

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Position Amino acid Mutation Disease Overlap with binding region
35 Lys Asn Myopathy,centronuclear,2(CNM2) -
151 Asp Asn Myopathy,centronuclear,2(CNM2) -
24 Arg Cys - -
145 Arg Cys Myopathy,centronuclear,2(CNM2) -
154 Arg Gln Myopathy,centronuclear,2(CNM2) -
234 Arg Cys Myopathy,centronuclear,2(CNM2) -
ELM instance Name Type Start End Partner
ELMI000298 LIG_AP2alpha_1 LIG 362 366 -
ELMI000629 LIG_Clathr_ClatBox_1 LIG 123 127 -
ELMI000449 LIG_Clathr_ClatBox_1 LIG 390 394 -
ELMI000452 LIG_Clathr_ClatBox_2 LIG 415 420 -
ELMI002443 LIG_SH3_3 LIG 308 314 -

Molecular function

Term Name % Distance from the top of the tree Annotated in BIN1_HUMAN
GO:0019900 kinase binding 31.2500 4 no
GO:0019901 protein kinase binding 28.7500 5 no
GO:0046872 metal ion binding 26.2500 4 no
GO:0017076 purine nucleotide binding 22.5000 4 no
GO:0032555 purine ribonucleotide binding 22.5000 4 no
GO:0003723 RNA binding 21.2500 4 no
GO:0035639 purine ribonucleoside triphosphate binding 21.2500 4 no
GO:0003779 actin binding 12.5000 4 yes
GO:0051020 GTPase binding 8.7500 4 yes
GO:0002020 protease binding 7.5000 4 yes
GO:0048156 tau protein binding 7.5000 4 yes
GO:0004866 endopeptidase inhibitor activity 3.7500 5 yes
GO:0030414 peptidase inhibitor activity 3.7500 4 yes
GO:0061135 endopeptidase regulator activity 3.7500 4 yes
GO:0019828 aspartic-type endopeptidase inhibitor activity 2.5000 6 yes
GO:0070063 RNA polymerase binding 2.5000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in BIN1_HUMAN
GO:0048522 positive regulation of cellular process 63.7500 4 yes
GO:0048523 negative regulation of cellular process 58.7500 4 yes
GO:0051128 regulation of cellular component organization 57.5000 4 yes
GO:0010646 regulation of cell communication 55.0000 4 no
GO:0031323 regulation of cellular metabolic process 51.2500 4 yes
GO:0060255 regulation of macromolecule metabolic process 51.2500 4 yes
GO:0051049 regulation of transport 48.7500 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 46.2500 4 yes
GO:0080090 regulation of primary metabolic process 46.2500 4 yes
GO:0022607 cellular component assembly 42.5000 4 yes
GO:0009893 positive regulation of metabolic process 41.2500 4 no
GO:0016192 vesicle-mediated transport 40.0000 4 yes
GO:0008104 protein localization 40.0000 4 no
GO:0009966 regulation of signal transduction 40.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 38.7500 5 no
GO:0006996 organelle organization 37.5000 4 yes
GO:0010468 regulation of gene expression 37.5000 5 yes
GO:0031325 positive regulation of cellular metabolic process 36.2500 5 no
GO:0009892 negative regulation of metabolic process 35.0000 4 yes
GO:0051130 positive regulation of cellular component organization 35.0000 5 yes
GO:0051246 regulation of protein metabolic process 35.0000 5 yes
GO:0060627 regulation of vesicle-mediated transport 35.0000 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 33.7500 5 yes
GO:0044087 regulation of cellular component biogenesis 33.7500 4 yes
GO:0051050 positive regulation of transport 33.7500 4 yes
GO:0009889 regulation of biosynthetic process 32.5000 4 yes
GO:0043933 protein-containing complex organization 32.5000 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 32.5000 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 32.5000 5 no
GO:0071702 organic substance transport 32.5000 4 no
GO:0071705 nitrogen compound transport 32.5000 4 no
GO:0006897 endocytosis 31.2500 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 30.0000 5 yes
GO:0031324 negative regulation of cellular metabolic process 30.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 30.0000 5 yes
GO:0015031 protein transport 30.0000 4 no
GO:0033043 regulation of organelle organization 28.7500 5 yes
GO:0065003 protein-containing complex assembly 28.7500 5 yes
GO:1902531 regulation of intracellular signal transduction 27.5000 5 no
GO:0050804 modulation of chemical synaptic transmission 26.2500 5 no
GO:0099177 regulation of trans-synaptic signaling 26.2500 4 no
GO:0031399 regulation of protein modification process 26.2500 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 yes
GO:0030100 regulation of endocytosis 25.0000 5 yes
GO:0051252 regulation of RNA metabolic process 25.0000 5 yes
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0019220 regulation of phosphate metabolic process 25.0000 6 no
GO:0051174 regulation of phosphorus metabolic process 25.0000 5 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0061024 membrane organization 23.7500 4 yes
GO:0006886 intracellular protein transport 23.7500 4 no
GO:0031344 regulation of cell projection organization 23.7500 5 no
GO:0036211 protein modification process 23.7500 4 no
GO:0043412 macromolecule modification 23.7500 4 no
GO:0048584 positive regulation of response to stimulus 23.7500 4 no
GO:0071310 cellular response to organic substance 23.7500 4 no
GO:0051247 positive regulation of protein metabolic process 23.7500 6 no
GO:0006355 regulation of DNA-templated transcription 22.5000 6 yes
GO:0010941 regulation of cell death 22.5000 4 yes
GO:0044057 regulation of system process 22.5000 4 yes
GO:1903506 regulation of nucleic acid-templated transcription 22.5000 7 yes
GO:2001141 regulation of RNA biosynthetic process 22.5000 6 yes
GO:0032880 regulation of protein localization 22.5000 5 no
GO:0051129 negative regulation of cellular component organization 22.5000 5 no
GO:0060341 regulation of cellular localization 22.5000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.5000 6 no
GO:0010647 positive regulation of cell communication 22.5000 5 no
GO:0023056 positive regulation of signaling 22.5000 4 no
GO:0120036 plasma membrane bounded cell projection organization 22.5000 5 no
GO:0044089 positive regulation of cellular component biogenesis 21.2500 5 yes
GO:0045595 regulation of cell differentiation 21.2500 4 yes
GO:0051240 positive regulation of multicellular organismal process 21.2500 4 yes
GO:0009891 positive regulation of biosynthetic process 21.2500 5 no
GO:0031328 positive regulation of cellular biosynthetic process 21.2500 6 no
GO:0042325 regulation of phosphorylation 21.2500 7 no
GO:0043269 regulation of ion transport 20.0000 5 yes
GO:0051248 negative regulation of protein metabolic process 20.0000 6 yes
GO:0043085 positive regulation of catalytic activity 18.7500 4 yes
GO:0051051 negative regulation of transport 18.7500 4 yes
GO:0034762 regulation of transmembrane transport 17.5000 4 yes
GO:0042981 regulation of apoptotic process 17.5000 6 yes
GO:0043067 regulation of programmed cell death 17.5000 5 yes
GO:0051094 positive regulation of developmental process 17.5000 4 yes
GO:0099003 vesicle-mediated transport in synapse 17.5000 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 16.2500 7 yes
GO:0009890 negative regulation of biosynthetic process 16.2500 5 yes
GO:0034765 regulation of ion transmembrane transport 16.2500 5 yes
GO:0043254 regulation of protein-containing complex assembly 16.2500 5 yes
GO:0045807 positive regulation of endocytosis 16.2500 5 yes
GO:0051493 regulation of cytoskeleton organization 16.2500 6 yes
GO:0051726 regulation of cell cycle 16.2500 4 yes
GO:1902903 regulation of supramolecular fiber organization 16.2500 5 yes
GO:1904062 regulation of cation transmembrane transport 16.2500 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 15.0000 6 yes
GO:0010564 regulation of cell cycle process 15.0000 5 yes
GO:0010942 positive regulation of cell death 15.0000 5 yes
GO:0030162 regulation of proteolysis 15.0000 6 yes
GO:0045597 positive regulation of cell differentiation 15.0000 5 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 15.0000 6 yes
GO:0048488 synaptic vesicle endocytosis 15.0000 5 yes
GO:0051253 negative regulation of RNA metabolic process 15.0000 6 yes
GO:0140238 presynaptic endocytosis 15.0000 4 yes
GO:0007010 cytoskeleton organization 13.7500 5 yes
GO:0010638 positive regulation of organelle organization 13.7500 6 yes
GO:0010959 regulation of metal ion transport 13.7500 6 yes
GO:0051241 negative regulation of multicellular organismal process 13.7500 4 yes
GO:0051336 regulation of hydrolase activity 13.7500 4 yes
GO:1902905 positive regulation of supramolecular fiber organization 13.7500 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 12.5000 6 yes
GO:0032970 regulation of actin filament-based process 12.5000 4 yes
GO:0034248 regulation of cellular amide metabolic process 12.5000 5 yes
GO:0051924 regulation of calcium ion transport 12.5000 7 yes
GO:0060284 regulation of cell development 12.5000 5 yes
GO:0090257 regulation of muscle system process 12.5000 5 yes
GO:2000026 regulation of multicellular organismal development 12.5000 4 yes
GO:0031334 positive regulation of protein-containing complex assembly 11.2500 6 yes
GO:0032535 regulation of cellular component size 11.2500 4 yes
GO:0045892 negative regulation of DNA-templated transcription 11.2500 7 yes
GO:0051345 positive regulation of hydrolase activity 11.2500 5 yes
GO:1902679 negative regulation of RNA biosynthetic process 11.2500 7 yes
GO:1903169 regulation of calcium ion transmembrane transport 11.2500 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 11.2500 8 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 10.0000 8 yes
GO:0006937 regulation of muscle contraction 10.0000 6 yes
GO:0010720 positive regulation of cell development 10.0000 6 yes
GO:0032956 regulation of actin cytoskeleton organization 10.0000 5 yes
GO:0043065 positive regulation of apoptotic process 10.0000 7 yes
GO:0043068 positive regulation of programmed cell death 10.0000 6 yes
GO:0050767 regulation of neurogenesis 10.0000 6 yes
GO:0051495 positive regulation of cytoskeleton organization 10.0000 7 yes
GO:0051960 regulation of nervous system development 10.0000 5 yes
GO:0110053 regulation of actin filament organization 10.0000 6 yes
GO:1903522 regulation of blood circulation 10.0000 5 yes
GO:0006942 regulation of striated muscle contraction 8.7500 7 yes
GO:0008016 regulation of heart contraction 8.7500 6 yes
GO:0032271 regulation of protein polymerization 8.7500 6 yes
GO:0032273 positive regulation of protein polymerization 8.7500 7 yes
GO:0043086 negative regulation of catalytic activity 8.7500 4 yes
GO:0055117 regulation of cardiac muscle contraction 8.7500 7 yes
GO:0034763 negative regulation of transmembrane transport 7.5000 5 yes
GO:0034766 negative regulation of ion transmembrane transport 7.5000 6 yes
GO:0043271 negative regulation of ion transport 7.5000 5 yes
GO:0050769 positive regulation of neurogenesis 7.5000 6 yes
GO:0051926 negative regulation of calcium ion transport 7.5000 6 yes
GO:0051962 positive regulation of nervous system development 7.5000 5 yes
GO:1902991 regulation of amyloid precursor protein catabolic process 7.5000 6 yes
GO:1903170 negative regulation of calcium ion transmembrane transport 7.5000 7 yes
GO:1904063 negative regulation of cation transmembrane transport 7.5000 7 yes
GO:0007034 vacuolar transport 6.2500 4 yes
GO:0007041 lysosomal transport 6.2500 5 yes
GO:0034249 negative regulation of cellular amide metabolic process 6.2500 6 yes
GO:0043087 regulation of GTPase activity 6.2500 5 yes
GO:0045664 regulation of neuron differentiation 6.2500 5 yes
GO:0052547 regulation of peptidase activity 6.2500 5 yes
GO:0052548 regulation of endopeptidase activity 6.2500 6 yes
GO:0098901 regulation of cardiac muscle cell action potential 6.2500 4 yes
GO:1902003 regulation of amyloid-beta formation 6.2500 6 yes
GO:1902992 negative regulation of amyloid precursor protein catabolic process 6.2500 7 yes
GO:0008064 regulation of actin polymerization or depolymerization 5.0000 6 yes
GO:0030832 regulation of actin filament length 5.0000 5 yes
GO:0030833 regulation of actin filament polymerization 5.0000 7 yes
GO:0030838 positive regulation of actin filament polymerization 5.0000 7 yes
GO:0043547 positive regulation of GTPase activity 5.0000 6 yes
GO:0051346 negative regulation of hydrolase activity 5.0000 5 yes
GO:0086004 regulation of cardiac muscle cell contraction 5.0000 6 yes
GO:1902430 negative regulation of amyloid-beta formation 5.0000 7 yes
GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 5.0000 7 yes
GO:1903115 regulation of actin filament-based movement 5.0000 5 yes
GO:1903523 negative regulation of blood circulation 5.0000 5 yes
GO:1905245 regulation of aspartic-type peptidase activity 5.0000 6 yes
GO:0006997 nucleus organization 3.7500 5 yes
GO:0008333 endosome to lysosome transport 3.7500 5 yes
GO:0010466 negative regulation of peptidase activity 3.7500 6 yes
GO:0010951 negative regulation of endopeptidase activity 3.7500 7 yes
GO:0014013 regulation of gliogenesis 3.7500 7 yes
GO:0014015 positive regulation of gliogenesis 3.7500 7 yes
GO:0043266 regulation of potassium ion transport 3.7500 7 yes
GO:0045822 negative regulation of heart contraction 3.7500 6 yes
GO:0045861 negative regulation of proteolysis 3.7500 7 yes
GO:0065005 protein-lipid complex assembly 3.7500 6 yes
GO:0071825 protein-lipid complex subunit organization 3.7500 5 yes
GO:0098911 regulation of ventricular cardiac muscle cell action potential 3.7500 5 yes
GO:1901379 regulation of potassium ion transmembrane transport 3.7500 7 yes
GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 3.7500 8 yes
GO:0033292 T-tubule organization 2.5000 5 yes
GO:0043267 negative regulation of potassium ion transport 2.5000 6 yes
GO:0045685 regulation of glial cell differentiation 2.5000 5 yes
GO:0045687 positive regulation of glial cell differentiation 2.5000 6 yes
GO:0045759 negative regulation of action potential 2.5000 4 yes
GO:0045932 negative regulation of muscle contraction 2.5000 5 yes
GO:0045988 negative regulation of striated muscle contraction 2.5000 6 yes
GO:0048710 regulation of astrocyte differentiation 2.5000 6 yes
GO:0048711 positive regulation of astrocyte differentiation 2.5000 7 yes
GO:0055118 negative regulation of cardiac muscle contraction 2.5000 7 yes
GO:0060988 lipid tube assembly 2.5000 7 yes
GO:0086091 regulation of heart rate by cardiac conduction 2.5000 4 yes
GO:0106135 negative regulation of cardiac muscle cell contraction 2.5000 5 yes
GO:1901380 negative regulation of potassium ion transmembrane transport 2.5000 7 yes
GO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 2.5000 8 yes
GO:1903946 negative regulation of ventricular cardiac muscle cell action potential 2.5000 5 yes
GO:1904878 negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 2.5000 8 yes
GO:1905246 negative regulation of aspartic-type peptidase activity 2.5000 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in BIN1_HUMAN
DOID:0050700 cardiomyopathy 3.7500 4 no
DOID:0060036 intrinsic cardiomyopathy 3.7500 5 no
DOID:114 heart disease 3.7500 3 no
DOID:0080000 muscular disease 2.5000 3 yes
DOID:0111216 autosomal recessive centronuclear myopathy 2.5000 7 yes
DOID:0111220 centronuclear myopathy 2 2.5000 8 yes
DOID:14717 centronuclear myopathy 2.5000 6 yes
DOID:423 myopathy 2.5000 5 yes
DOID:66 muscle tissue disease 2.5000 4 yes
DOID:2843 long QT syndrome 2.5000 6 no
DOID:1289 neurodegenerative disease 2.5000 4 no
DOID:331 central nervous system disease 2.5000 3 no
DOID:0060674 catecholaminergic polymorphic ventricular tachycardia 2.5000 5 no
DOID:10273 heart conduction disease 2.5000 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ITA1_HUMAN [view interactions] Low throughput no yes
ITA3_HUMAN [view entry] [view interactions] Low throughput yes yes
ITA6_HUMAN [view interactions] Low throughput no yes
FHL2_HUMAN [view interactions] Low throughput no yes
MYC_HUMAN [view interactions] Low throughput no yes
CLIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
SYNE2_HUMAN [view interactions] Low throughput no no
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
SYN1_HUMAN [view entry] [view interactions] Low throughput yes no
ACK1_HUMAN [view interactions] Low throughput no yes
SYNJ1_HUMAN [view entry] [view interactions] Low throughput yes yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
WASL_HUMAN [view entry] [view interactions] Low throughput yes yes
E2F1_HUMAN [view interactions] Low throughput no yes
ITCH_HUMAN [view interactions] Low throughput no yes
EH1L1_HUMAN [view interactions] Low throughput no yes
CHM4B_HUMAN [view entry] [view interactions] Low throughput yes yes
CLUS_HUMAN [view entry] [view interactions] Low throughput yes yes
BECN1_HUMAN [view interactions] Low throughput no yes
FCG3A_HUMAN [view interactions] Low throughput no no
FCG2A_HUMAN [view interactions] Low throughput no no
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
BACE1_HUMAN [view interactions] Low throughput no yes
PLD1_HUMAN [view interactions] Low throughput no no
PLD2_HUMAN [view interactions] Low throughput no yes
SOS2_HUMAN [view interactions] Low throughput no yes
AP2A1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAP1A_HUMAN [view entry] [view interactions] Low throughput yes no
ACTS_HUMAN [view interactions] Low throughput no no
ACTG_HUMAN [view entry] [view interactions] Low throughput yes yes
MBNL1_HUMAN [view interactions] Low throughput no yes
RAB8A_HUMAN [view entry] [view interactions] Low throughput yes no
RAB8B_HUMAN [view entry] [view interactions] Low throughput yes no
XRCC6_HUMAN [view interactions] Low throughput no yes
XRCC5_HUMAN [view interactions] Low throughput no yes
ARF6_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLGP4_HUMAN [view entry] [view interactions] Low throughput yes yes
XRCC4_HUMAN [view interactions] Low throughput no yes
F16P1_HUMAN [view interactions] Low throughput no no
REPS2_HUMAN [view entry] [view interactions] Low throughput yes no
RIN3_HUMAN [view interactions] Low throughput no yes
SNX4_HUMAN [view entry] [view interactions] Low throughput yes yes
CNRG_HUMAN [view interactions] Low throughput no no
MTM1_HUMAN [view interactions] Low throughput no yes
SOS1_HUMAN [view entry] [view interactions] Low throughput yes yes
AMPH_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
AP2A2_HUMAN [view entry] [view interactions] Low throughput yes yes
NECP1_HUMAN [view interactions] Low throughput no no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
BIN1_HUMAN [view entry] [view interactions] Low throughput yes yes
BIN2_HUMAN [view interactions] Low throughput no no
DYN3_HUMAN [view entry] [view interactions] Low throughput yes no
DYN2_HUMAN [view entry] [view interactions] Low throughput yes yes
RYR1_HUMAN [view interactions] Low throughput no no
CACB1_HUMAN [view entry] [view interactions] Low throughput yes yes
WBP2_HUMAN [view interactions] High throughput no yes
HECD1_HUMAN [view interactions] High throughput no yes
ZN451_HUMAN [view entry] [view interactions] High throughput yes no
GAS6_HUMAN [view interactions] High throughput no no
KS6C1_HUMAN [view entry] [view interactions] High throughput yes no
GNL3_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
PAX6_HUMAN [view interactions] High throughput no no
RAB24_HUMAN [view interactions] High throughput no no
PEPL_HUMAN [view interactions] High throughput no yes
YETS2_HUMAN [view interactions] High throughput no no
LRIF1_HUMAN [view interactions] High throughput no yes
PSA7_HUMAN [view interactions] High throughput no yes
PTPRD_HUMAN [view entry] [view interactions] High throughput yes no
BCAT2_HUMAN [view interactions] High throughput no no
RBP2_HUMAN [view interactions] High throughput no yes
RYR2_HUMAN [view entry] [view interactions] High throughput yes yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
TSNAX_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view interactions] High throughput no yes
MCAF2_HUMAN [view interactions] High throughput no yes
RANB3_HUMAN [view interactions] High throughput no yes
PIAS1_HUMAN [view interactions] High throughput no yes
SYNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
SIAT9_HUMAN [view interactions] High throughput no no
DPM1_HUMAN [view entry] [view interactions] High throughput yes yes
PIAS2_HUMAN [view interactions] High throughput no yes
ZN251_HUMAN [view interactions] High throughput no yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
Z518A_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
NUFP1_HUMAN [view interactions] High throughput no yes
DGUOK_HUMAN [view interactions] High throughput no yes
GRL1A_HUMAN [view interactions] High throughput no no
IPO8_HUMAN [view interactions] High throughput no no
KLF8_HUMAN [view interactions] High throughput no no
VPS18_HUMAN [view entry] [view interactions] High throughput yes no
OXDA_HUMAN [view interactions] High throughput no no
CNDD3_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
HDAC6_HUMAN [view interactions] High throughput no yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
NONO_HUMAN [view interactions] High throughput no yes
PLK1_HUMAN [view interactions] High throughput no yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
CDC73_HUMAN [view interactions] High throughput no yes
IF2B1_HUMAN [view interactions] High throughput no no
BGAL_HUMAN [view interactions] High throughput no yes
DHX9_HUMAN [view interactions] High throughput no yes
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
CBARP_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
SHLB1_HUMAN [view interactions] High throughput no yes
SH3G2_HUMAN [view entry] [view interactions] High throughput yes yes
SH3G3_HUMAN [view entry] [view interactions] High throughput yes no
HYOU1_HUMAN [view interactions] High throughput no yes
PDE4D_HUMAN [view entry] [view interactions] High throughput yes yes
RBM12_HUMAN [view interactions] High throughput no yes
STMN1_HUMAN [view interactions] High throughput no yes
ASAP2_HUMAN [view interactions] High throughput no yes
ATX2_HUMAN [view interactions] High throughput no yes
AP180_HUMAN [view entry] [view interactions] High throughput yes yes
SYNEM_HUMAN [view entry] [view interactions] High throughput yes no
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP7_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
IRS4_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
NECP2_HUMAN [view interactions] High throughput no yes
MERTK_HUMAN [view interactions] High throughput no yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
HOME1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
RFX3_HUMAN [view interactions] High throughput no yes
ZBTB3_HUMAN [view interactions] High throughput no yes
CUX1_HUMAN [view interactions] High throughput no yes
PE2R4_HUMAN [view interactions] High throughput no yes
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
SNAPN_HUMAN [view interactions] High throughput no yes
PIAS3_HUMAN [view interactions] High throughput no yes
PWP2A_HUMAN [view interactions] High throughput no no
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
AGRA3_HUMAN [view interactions] High throughput no yes
RNB3L_HUMAN [view interactions] High throughput no yes
FHL1_HUMAN [view interactions] High throughput no no
MTF2_HUMAN [view interactions] High throughput no no
ATF6A_HUMAN [view interactions] High throughput no yes
SMHD1_HUMAN [view interactions] High throughput no yes
EPS15_HUMAN [view entry] [view interactions] Computational yes yes
PP2BB_HUMAN [view entry] [view interactions] Computational yes yes
PP2BC_HUMAN [view interactions] Computational no yes
P73_HUMAN [view interactions] Computational no no
EPN1_HUMAN [view entry] [view interactions] Computational yes yes
M4A6A_HUMAN [view interactions] Computational no yes
CD2AP_HUMAN [view interactions] Computational no no
PP2BA_HUMAN [view entry] [view interactions] Computational yes yes
AP2M1_HUMAN [view entry] [view interactions] Computational yes yes
APOE_HUMAN [view entry] [view interactions] Computational yes yes
ABCA7_HUMAN [view interactions] Computational no yes
WASP_HUMAN [view interactions] Computational no yes
PICAL_HUMAN [view entry] [view interactions] Computational yes yes
BIN3_HUMAN [view interactions] Computational no yes