Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KS6C1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KS6C1_HUMAN
GO:0017076 purine nucleotide binding 50.0000 4 yes
GO:0032555 purine ribonucleotide binding 50.0000 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 50.0000 4 yes
GO:0051020 GTPase binding 50.0000 4 no
GO:0016462 pyrophosphatase activity 41.6667 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 41.6667 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 41.6667 6 no
GO:0005525 GTP binding 33.3333 5 no
GO:0019001 guanyl nucleotide binding 33.3333 5 no
GO:0032561 guanyl ribonucleotide binding 33.3333 5 no
GO:0005524 ATP binding 25.0000 5 yes
GO:0030554 adenyl nucleotide binding 25.0000 5 yes
GO:0032559 adenyl ribonucleotide binding 25.0000 5 yes
GO:0035091 phosphatidylinositol binding 25.0000 4 yes
GO:0003924 GTPase activity 25.0000 7 no
GO:0019003 GDP binding 25.0000 4 no
GO:0031267 small GTPase binding 25.0000 5 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0048156 tau protein binding 25.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in KS6C1_HUMAN
GO:0048522 positive regulation of cellular process 75.0000 4 no
GO:0051128 regulation of cellular component organization 66.6667 4 no
GO:0006996 organelle organization 66.6667 4 no
GO:0008104 protein localization 58.3333 4 no
GO:0051049 regulation of transport 58.3333 4 no
GO:0010646 regulation of cell communication 50.0000 4 no
GO:0015031 protein transport 50.0000 4 no
GO:0016192 vesicle-mediated transport 50.0000 4 no
GO:0071702 organic substance transport 50.0000 4 no
GO:0071705 nitrogen compound transport 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0061024 membrane organization 50.0000 4 no
GO:0006886 intracellular protein transport 41.6667 4 no
GO:0051050 positive regulation of transport 41.6667 4 no
GO:0060627 regulation of vesicle-mediated transport 41.6667 4 no
GO:0009966 regulation of signal transduction 41.6667 4 no
GO:0016050 vesicle organization 41.6667 5 no
GO:0031323 regulation of cellular metabolic process 41.6667 4 no
GO:0048584 positive regulation of response to stimulus 41.6667 4 no
GO:0022607 cellular component assembly 41.6667 4 no
GO:0051171 regulation of nitrogen compound metabolic process 41.6667 4 no
GO:0051246 regulation of protein metabolic process 41.6667 5 no
GO:0006897 endocytosis 33.3333 5 no
GO:0030100 regulation of endocytosis 33.3333 5 no
GO:0033043 regulation of organelle organization 33.3333 5 no
GO:0044087 regulation of cellular component biogenesis 33.3333 4 no
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0010647 positive regulation of cell communication 33.3333 5 no
GO:0016197 endosomal transport 33.3333 4 no
GO:0023056 positive regulation of signaling 33.3333 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:1902533 positive regulation of intracellular signal transduction 33.3333 6 no
GO:0006906 vesicle fusion 33.3333 6 no
GO:0007034 vacuolar transport 33.3333 4 no
GO:0007041 lysosomal transport 33.3333 5 no
GO:0048284 organelle fusion 33.3333 5 no
GO:0061025 membrane fusion 33.3333 5 no
GO:0090174 organelle membrane fusion 33.3333 6 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0010468 regulation of gene expression 33.3333 5 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0043085 positive regulation of catalytic activity 33.3333 4 no
GO:0048523 negative regulation of cellular process 33.3333 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0016482 cytosolic transport 25.0000 4 no
GO:0032535 regulation of cellular component size 25.0000 4 no
GO:0071310 cellular response to organic substance 25.0000 4 no
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0050776 regulation of immune response 25.0000 4 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0008333 endosome to lysosome transport 25.0000 5 no
GO:0001817 regulation of cytokine production 25.0000 4 no
GO:0001932 regulation of protein phosphorylation 25.0000 7 no
GO:0001934 positive regulation of protein phosphorylation 25.0000 8 no
GO:0009889 regulation of biosynthetic process 25.0000 4 no
GO:0009892 negative regulation of metabolic process 25.0000 4 no
GO:0009894 regulation of catabolic process 25.0000 4 no
GO:0010556 regulation of macromolecule biosynthetic process 25.0000 5 no
GO:0010562 positive regulation of phosphorus metabolic process 25.0000 6 no
GO:0010941 regulation of cell death 25.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0019220 regulation of phosphate metabolic process 25.0000 6 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 25.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 25.0000 5 no
GO:0031399 regulation of protein modification process 25.0000 6 no
GO:0031401 positive regulation of protein modification process 25.0000 7 no
GO:0033674 positive regulation of kinase activity 25.0000 6 no
GO:0042176 regulation of protein catabolic process 25.0000 5 no
GO:0042325 regulation of phosphorylation 25.0000 7 no
GO:0042327 positive regulation of phosphorylation 25.0000 8 no
GO:0042981 regulation of apoptotic process 25.0000 6 no
GO:0043067 regulation of programmed cell death 25.0000 5 no
GO:0043549 regulation of kinase activity 25.0000 5 no
GO:0043933 protein-containing complex organization 25.0000 4 no
GO:0045859 regulation of protein kinase activity 25.0000 6 no
GO:0045860 positive regulation of protein kinase activity 25.0000 7 no
GO:0045937 positive regulation of phosphate metabolic process 25.0000 7 no
GO:0051174 regulation of phosphorus metabolic process 25.0000 5 no
GO:0051336 regulation of hydrolase activity 25.0000 4 no
GO:0051338 regulation of transferase activity 25.0000 4 no
GO:0051347 positive regulation of transferase activity 25.0000 5 no
GO:0051726 regulation of cell cycle 25.0000 4 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:1990138 neuron projection extension 25.0000 4 no
GO:0044089 positive regulation of cellular component biogenesis 25.0000 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SPHK1_HUMAN [view interactions] Low throughput no yes
PBX2_HUMAN [view interactions] High throughput no yes
PRDX3_HUMAN [view interactions] High throughput no yes
DEN6A_HUMAN [view interactions] High throughput no yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
HDAC4_HUMAN [view interactions] High throughput no yes
BIN1_HUMAN [view entry] [view interactions] High throughput yes yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
ETS1_HUMAN [view interactions] High throughput no no
TGON2_HUMAN [view interactions] High throughput no yes
VDR_HUMAN [view interactions] High throughput no no
SAAL1_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
VPS39_HUMAN [view entry] [view interactions] High throughput yes no
RN123_HUMAN [view interactions] High throughput no yes
DDX58_HUMAN [view interactions] High throughput no yes
SIR6_HUMAN [view interactions] High throughput no yes
ANFY1_HUMAN [view entry] [view interactions] High throughput yes yes
CAV1_HUMAN [view interactions] High throughput no no
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes