DLGP4_HUMAN
Evidence for PS localization
Functions
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DLGP4_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 29.0909 | 4 | no |
| GO:0000166 | nucleotide binding | 27.2727 | 4 | no |
| GO:0017076 | purine nucleotide binding | 27.2727 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.2727 | 4 | no |
| GO:0019900 | kinase binding | 25.4545 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.4545 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DLGP4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 67.2727 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 54.5455 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 52.7273 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 50.9091 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 49.0909 | 4 | no |
| GO:0010646 | regulation of cell communication | 49.0909 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 49.0909 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 41.8182 | 5 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 38.1818 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.1818 | 4 | no |
| GO:0008104 | protein localization | 36.3636 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.5455 | 5 | no |
| GO:0030030 | cell projection organization | 32.7273 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.7273 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.9091 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 30.9091 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.9091 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.9091 | 4 | no |
| GO:0031399 | regulation of protein modification process | 30.9091 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.9091 | 4 | no |
| GO:0051049 | regulation of transport | 29.0909 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 29.0909 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 29.0909 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 29.0909 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 29.0909 | 5 | no |
| GO:0010468 | regulation of gene expression | 29.0909 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.0909 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 29.0909 | 6 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.0909 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.0909 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 29.0909 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 29.0909 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 29.0909 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 27.2727 | 5 | no |
| GO:0043933 | protein-containing complex organization | 27.2727 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.2727 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.2727 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
| GO:0141124 | intracellular signaling cassette | 27.2727 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 25.4545 | 6 | no |
| GO:0007010 | cytoskeleton organization | 25.4545 | 5 | no |
| GO:0033043 | regulation of organelle organization | 25.4545 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.4545 | 7 | no |
| GO:0042127 | regulation of cell population proliferation | 25.4545 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 25.4545 | 7 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.6364 | 5 | no |
| GO:0050890 | cognition | 23.6364 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 21.8182 | 7 | no |
| GO:0032970 | regulation of actin filament-based process | 21.8182 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 21.8182 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 21.8182 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 21.8182 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.8182 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BIN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZNF35_HUMAN | [view interactions] | High throughput | no | no |
| MCA3_HUMAN | [view interactions] | High throughput | no | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| TRM6_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN5_HUMAN | [view interactions] | High throughput | no | no |
| H2BFS_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1H_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHL3_HUMAN | [view interactions] | High throughput | no | no |
| NHRF2_HUMAN | [view interactions] | High throughput | no | no |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| FHL5_HUMAN | [view interactions] | High throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A16A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKBP6_HUMAN | [view interactions] | High throughput | no | no |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| PPR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3R1_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3A_HUMAN | [view interactions] | High throughput | no | no |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| PAR6B_HUMAN | [view interactions] | High throughput | no | no |
| TYK2_HUMAN | [view interactions] | High throughput | no | no |
| B4GT1_HUMAN | [view interactions] | High throughput | no | yes |
| NEK2_HUMAN | [view interactions] | High throughput | no | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| CNDG2_HUMAN | [view interactions] | High throughput | no | yes |
| FGD6_HUMAN | [view interactions] | High throughput | no | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DEOC_HUMAN | [view interactions] | High throughput | no | no |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THOC4_HUMAN | [view interactions] | High throughput | no | no |
| SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS42_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRCC2_HUMAN | [view interactions] | High throughput | no | no |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAGI3_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| CHD5_HUMAN | [view interactions] | High throughput | no | no |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBSK_HUMAN | [view interactions] | High throughput | no | yes |
| RTCB_HUMAN | [view interactions] | High throughput | no | yes |
| H2B2F_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC4C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |