PPR1B_HUMAN
Inhibitor of protein-phosphatase 1. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001078 | DOC_PP1_RVXF_1 | DOC | 5 | 12 | - |
ELMI001078 | DOC_PP1_RVXF_1 | DOC | 5 | 12 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in PPR1B_HUMAN |
---|---|---|---|---|
GO:0000166 | nucleotide binding | 44.4444 | 4 | no |
GO:0004674 | protein serine/threonine kinase activity | 44.4444 | 4 | no |
GO:0005524 | ATP binding | 44.4444 | 5 | no |
GO:0016301 | kinase activity | 44.4444 | 4 | no |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 44.4444 | 4 | no |
GO:0017076 | purine nucleotide binding | 44.4444 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 44.4444 | 6 | no |
GO:0032555 | purine ribonucleotide binding | 44.4444 | 4 | no |
GO:0032559 | adenyl ribonucleotide binding | 44.4444 | 5 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 44.4444 | 4 | no |
GO:0043168 | anion binding | 44.4444 | 4 | no |
GO:0106310 | protein serine kinase activity | 44.4444 | 4 | no |
GO:0043169 | cation binding | 33.3333 | 4 | no |
GO:0046872 | metal ion binding | 33.3333 | 5 | no |
GO:0051879 | Hsp90 protein binding | 22.2222 | 4 | no |
GO:0004722 | protein serine/threonine phosphatase activity | 22.2222 | 4 | no |
GO:0008157 | protein phosphatase 1 binding | 22.2222 | 6 | no |
GO:0016791 | phosphatase activity | 22.2222 | 5 | no |
GO:0017018 | myosin phosphatase activity | 22.2222 | 5 | no |
GO:0019902 | phosphatase binding | 22.2222 | 4 | no |
GO:0019903 | protein phosphatase binding | 22.2222 | 5 | no |
GO:0042578 | phosphoric ester hydrolase activity | 22.2222 | 4 | no |
GO:0019900 | kinase binding | 22.2222 | 4 | no |
GO:0019901 | protein kinase binding | 22.2222 | 5 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in PPR1B_HUMAN |
---|---|---|---|---|
GO:0031323 | regulation of cellular metabolic process | 77.7778 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 77.7778 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 77.7778 | 4 | no |
GO:0048523 | negative regulation of cellular process | 66.6667 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 66.6667 | 5 | yes |
GO:0080090 | regulation of primary metabolic process | 66.6667 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 66.6667 | 4 | no |
GO:0010646 | regulation of cell communication | 66.6667 | 4 | no |
GO:0036211 | protein modification process | 66.6667 | 4 | no |
GO:0043412 | macromolecule modification | 66.6667 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 55.5556 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 55.5556 | 4 | no |
GO:0009894 | regulation of catabolic process | 55.5556 | 4 | no |
GO:0009966 | regulation of signal transduction | 55.5556 | 4 | no |
GO:0010468 | regulation of gene expression | 55.5556 | 6 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 55.5556 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 55.5556 | 5 | no |
GO:0051128 | regulation of cellular component organization | 55.5556 | 4 | no |
GO:0009416 | response to light stimulus | 44.4444 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 44.4444 | 5 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 44.4444 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 44.4444 | 6 | yes |
GO:0071310 | cellular response to organic substance | 44.4444 | 4 | yes |
GO:0090304 | nucleic acid metabolic process | 44.4444 | 4 | yes |
GO:0006468 | protein phosphorylation | 44.4444 | 5 | no |
GO:0006915 | apoptotic process | 44.4444 | 4 | no |
GO:0010647 | positive regulation of cell communication | 44.4444 | 5 | no |
GO:0016310 | phosphorylation | 44.4444 | 5 | no |
GO:0018105 | peptidyl-serine phosphorylation | 44.4444 | 6 | no |
GO:0018193 | peptidyl-amino acid modification | 44.4444 | 5 | no |
GO:0018209 | peptidyl-serine modification | 44.4444 | 6 | no |
GO:0023056 | positive regulation of signaling | 44.4444 | 4 | no |
GO:0030162 | regulation of proteolysis | 44.4444 | 6 | no |
GO:0042981 | regulation of apoptotic process | 44.4444 | 5 | no |
GO:0043067 | regulation of programmed cell death | 44.4444 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 44.4444 | 4 | no |
GO:0051726 | regulation of cell cycle | 44.4444 | 4 | no |
GO:0045595 | regulation of cell differentiation | 44.4444 | 4 | no |
GO:0060341 | regulation of cellular localization | 44.4444 | 4 | no |
GO:0010243 | response to organonitrogen compound | 33.3333 | 4 | yes |
GO:0071417 | cellular response to organonitrogen compound | 33.3333 | 4 | yes |
GO:1901699 | cellular response to nitrogen compound | 33.3333 | 4 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 33.3333 | 4 | yes |
GO:0009895 | negative regulation of catabolic process | 33.3333 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 33.3333 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 33.3333 | 5 | no |
GO:0010648 | negative regulation of cell communication | 33.3333 | 5 | no |
GO:0023057 | negative regulation of signaling | 33.3333 | 4 | no |
GO:0045861 | negative regulation of proteolysis | 33.3333 | 7 | no |
GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
GO:1903050 | regulation of proteolysis involved in protein catabolic process | 33.3333 | 7 | no |
GO:2001233 | regulation of apoptotic signaling pathway | 33.3333 | 5 | no |
GO:0050767 | regulation of neurogenesis | 33.3333 | 6 | no |
GO:0051960 | regulation of nervous system development | 33.3333 | 5 | no |
GO:0060284 | regulation of cell development | 33.3333 | 5 | no |
GO:2000026 | regulation of multicellular organismal development | 33.3333 | 4 | no |
GO:0010506 | regulation of autophagy | 33.3333 | 6 | no |
GO:0031329 | regulation of cellular catabolic process | 33.3333 | 5 | no |
GO:0032880 | regulation of protein localization | 33.3333 | 5 | no |
GO:0070201 | regulation of establishment of protein localization | 33.3333 | 6 | no |
GO:1903829 | positive regulation of protein localization | 33.3333 | 5 | no |
GO:1904951 | positive regulation of establishment of protein localization | 33.3333 | 6 | no |
GO:0032386 | regulation of intracellular transport | 33.3333 | 5 | no |
GO:0046822 | regulation of nucleocytoplasmic transport | 33.3333 | 6 | no |
GO:0051049 | regulation of transport | 33.3333 | 4 | no |
GO:0007612 | learning | 22.2222 | 4 | yes |
GO:0008306 | associative learning | 22.2222 | 5 | yes |
GO:0008542 | visual learning | 22.2222 | 4 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 22.2222 | 6 | yes |
GO:0016070 | RNA metabolic process | 22.2222 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 22.2222 | 6 | yes |
GO:0031399 | regulation of protein modification process | 22.2222 | 6 | yes |
GO:0031400 | negative regulation of protein modification process | 22.2222 | 7 | yes |
GO:0043086 | negative regulation of catalytic activity | 22.2222 | 4 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 22.2222 | 7 | yes |
GO:0048148 | behavioral response to cocaine | 22.2222 | 4 | yes |
GO:0050890 | cognition | 22.2222 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 22.2222 | 5 | yes |
GO:0051336 | regulation of hydrolase activity | 22.2222 | 4 | yes |
GO:0051346 | negative regulation of hydrolase activity | 22.2222 | 5 | yes |
GO:0001558 | regulation of cell growth | 22.2222 | 4 | no |
GO:0006259 | DNA metabolic process | 22.2222 | 5 | no |
GO:0006281 | DNA repair | 22.2222 | 5 | no |
GO:0006302 | double-strand break repair | 22.2222 | 6 | no |
GO:0006417 | regulation of translation | 22.2222 | 6 | no |
GO:0006974 | DNA damage response | 22.2222 | 4 | no |
GO:0008284 | positive regulation of cell population proliferation | 22.2222 | 5 | no |
GO:0009890 | negative regulation of biosynthetic process | 22.2222 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 22.2222 | 4 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.2222 | 6 | no |
GO:0010564 | regulation of cell cycle process | 22.2222 | 5 | no |
GO:0010608 | post-transcriptional regulation of gene expression | 22.2222 | 7 | no |
GO:0016055 | Wnt signaling pathway | 22.2222 | 4 | no |
GO:0018107 | peptidyl-threonine phosphorylation | 22.2222 | 6 | no |
GO:0018210 | peptidyl-threonine modification | 22.2222 | 6 | no |
GO:0030111 | regulation of Wnt signaling pathway | 22.2222 | 5 | no |
GO:0031327 | negative regulation of cellular biosynthetic process | 22.2222 | 6 | no |
GO:0042127 | regulation of cell population proliferation | 22.2222 | 4 | no |
GO:0042176 | regulation of protein catabolic process | 22.2222 | 5 | no |
GO:0043066 | negative regulation of apoptotic process | 22.2222 | 6 | no |
GO:0043069 | negative regulation of programmed cell death | 22.2222 | 5 | no |
GO:0051983 | regulation of chromosome segregation | 22.2222 | 6 | no |
GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | 22.2222 | 8 | no |
GO:1905818 | regulation of chromosome separation | 22.2222 | 7 | no |
GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 22.2222 | 5 | no |
GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 22.2222 | 6 | no |
GO:2001234 | negative regulation of apoptotic signaling pathway | 22.2222 | 6 | no |
GO:0005976 | polysaccharide metabolic process | 22.2222 | 4 | no |
GO:0005977 | glycogen metabolic process | 22.2222 | 6 | no |
GO:0006109 | regulation of carbohydrate metabolic process | 22.2222 | 5 | no |
GO:0006112 | energy reserve metabolic process | 22.2222 | 5 | no |
GO:0006470 | protein dephosphorylation | 22.2222 | 5 | no |
GO:0009648 | photoperiodism | 22.2222 | 5 | no |
GO:0015980 | energy derivation by oxidation of organic compounds | 22.2222 | 4 | no |
GO:0016311 | dephosphorylation | 22.2222 | 5 | no |
GO:0043065 | positive regulation of apoptotic process | 22.2222 | 6 | no |
GO:0043068 | positive regulation of programmed cell death | 22.2222 | 5 | no |
GO:0043153 | entrainment of circadian clock by photoperiod | 22.2222 | 4 | no |
GO:0043255 | regulation of carbohydrate biosynthetic process | 22.2222 | 5 | no |
GO:0043393 | regulation of protein binding | 22.2222 | 4 | no |
GO:0043467 | regulation of generation of precursor metabolites and energy | 22.2222 | 5 | no |
GO:0043470 | regulation of carbohydrate catabolic process | 22.2222 | 5 | no |
GO:0043933 | protein-containing complex organization | 22.2222 | 4 | no |
GO:0044042 | glucan metabolic process | 22.2222 | 5 | no |
GO:0007411 | axon guidance | 22.2222 | 8 | no |
GO:0010720 | positive regulation of cell development | 22.2222 | 6 | no |
GO:0010975 | regulation of neuron projection development | 22.2222 | 7 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 22.2222 | 4 | no |
GO:0030030 | cell projection organization | 22.2222 | 4 | no |
GO:0031175 | neuron projection development | 22.2222 | 6 | no |
GO:0031344 | regulation of cell projection organization | 22.2222 | 5 | no |
GO:0032870 | cellular response to hormone stimulus | 22.2222 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.2222 | 4 | no |
GO:0045597 | positive regulation of cell differentiation | 22.2222 | 5 | no |
GO:0048666 | neuron development | 22.2222 | 4 | no |
GO:0050769 | positive regulation of neurogenesis | 22.2222 | 6 | no |
GO:0050770 | regulation of axonogenesis | 22.2222 | 5 | no |
GO:0050807 | regulation of synapse organization | 22.2222 | 5 | no |
GO:0051093 | negative regulation of developmental process | 22.2222 | 4 | no |
GO:0051094 | positive regulation of developmental process | 22.2222 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 22.2222 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 22.2222 | 4 | no |
GO:0051241 | negative regulation of multicellular organismal process | 22.2222 | 4 | no |
GO:0051961 | negative regulation of nervous system development | 22.2222 | 5 | no |
GO:0051962 | positive regulation of nervous system development | 22.2222 | 5 | no |
GO:0097485 | neuron projection guidance | 22.2222 | 7 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.2222 | 6 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 22.2222 | 5 | no |
GO:1901888 | regulation of cell junction assembly | 22.2222 | 5 | no |
GO:0048232 | male gamete generation | 22.2222 | 4 | no |
GO:1903533 | regulation of protein targeting | 22.2222 | 7 | no |
GO:0006886 | intracellular protein transport | 22.2222 | 4 | no |
GO:0008104 | protein localization | 22.2222 | 4 | no |
GO:0015031 | protein transport | 22.2222 | 4 | no |
GO:0016241 | regulation of macroautophagy | 22.2222 | 7 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.2222 | 5 | no |
GO:0022607 | cellular component assembly | 22.2222 | 4 | no |
GO:0033157 | regulation of intracellular protein transport | 22.2222 | 6 | no |
GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 22.2222 | 5 | no |
GO:0046825 | regulation of protein export from nucleus | 22.2222 | 7 | no |
GO:0050804 | modulation of chemical synaptic transmission | 22.2222 | 5 | no |
GO:0051046 | regulation of secretion | 22.2222 | 5 | no |
GO:0051047 | positive regulation of secretion | 22.2222 | 5 | no |
GO:0051050 | positive regulation of transport | 22.2222 | 4 | no |
GO:0051223 | regulation of protein transport | 22.2222 | 5 | no |
GO:0071702 | organic substance transport | 22.2222 | 4 | no |
GO:0071705 | nitrogen compound transport | 22.2222 | 4 | no |
GO:0099177 | regulation of trans-synaptic signaling | 22.2222 | 4 | no |
GO:0141124 | intracellular signaling cassette | 22.2222 | 4 | no |
GO:1903530 | regulation of secretion by cell | 22.2222 | 4 | no |
GO:1903532 | positive regulation of secretion by cell | 22.2222 | 5 | no |
GO:0030182 | neuron differentiation | 22.2222 | 4 | no |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
KLHL6_HUMAN | [view interactions] | High throughput | no | no |
DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ROBO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTBL_HUMAN | [view interactions] | High throughput | no | no |
CDK5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |