TIAM1_HUMAN
Evidence for PS localization
Functions
Guanyl-nucleotide exchange factor that activates RHO-like proteins and connects extracellular signals to cytoskeletal activities. Activates RAC1, CDC42, and to a lesser extent RHOA and their downstream signaling to regulate processes like cell adhesion and cell migration. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI004550 | LIG_CaMK_CASK_1 | LIG | 1572 | 1578 | - |
| ELMI004550 | LIG_CaMK_CASK_1 | LIG | 1572 | 1578 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TIAM1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 40.0000 | 4 | no |
| GO:0000166 | nucleotide binding | 37.6471 | 4 | no |
| GO:0017076 | purine nucleotide binding | 37.6471 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 37.6471 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 37.6471 | 4 | no |
| GO:0043169 | cation binding | 24.7059 | 4 | no |
| GO:0019900 | kinase binding | 22.3529 | 4 | yes |
| GO:0046872 | metal ion binding | 22.3529 | 5 | no |
| GO:0005524 | ATP binding | 21.1765 | 5 | no |
| GO:0016301 | kinase activity | 21.1765 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 21.1765 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.1765 | 5 | no |
| GO:0019901 | protein kinase binding | 18.8235 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 9.4118 | 4 | yes |
| GO:0015631 | tubulin binding | 5.8824 | 4 | yes |
| GO:1990782 | protein tyrosine kinase binding | 4.7059 | 6 | yes |
| GO:0008017 | microtubule binding | 3.5294 | 5 | yes |
| GO:0030971 | receptor tyrosine kinase binding | 3.5294 | 4 | yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 2.3529 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TIAM1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.3529 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 58.8235 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.2941 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.1176 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 51.7647 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 51.7647 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 49.4118 | 4 | yes |
| GO:0051049 | regulation of transport | 45.8824 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 45.8824 | 4 | yes |
| GO:0008104 | protein localization | 43.5294 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 42.3529 | 4 | no |
| GO:0010468 | regulation of gene expression | 42.3529 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.3529 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 42.3529 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 41.1765 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 37.6471 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 36.4706 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 36.4706 | 5 | no |
| GO:0060341 | regulation of cellular localization | 35.2941 | 4 | yes |
| GO:0006996 | organelle organization | 35.2941 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 35.2941 | 4 | no |
| GO:0023056 | positive regulation of signaling | 35.2941 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 34.1176 | 5 | no |
| GO:0022607 | cellular component assembly | 32.9412 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 31.7647 | 6 | no |
| GO:0009893 | positive regulation of metabolic process | 31.7647 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 31.7647 | 5 | no |
| GO:0032880 | regulation of protein localization | 30.5882 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 29.4118 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.4118 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.4118 | 5 | no |
| GO:0036211 | protein modification process | 29.4118 | 4 | no |
| GO:0043412 | macromolecule modification | 29.4118 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 27.0588 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 27.0588 | 6 | no |
| GO:0051050 | positive regulation of transport | 27.0588 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.0588 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 27.0588 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 27.0588 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.0588 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.0588 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.8824 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.8824 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.7059 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 24.7059 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 24.7059 | 7 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.7059 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.7059 | 7 | no |
| GO:0071702 | organic substance transport | 24.7059 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.7059 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.7059 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 24.7059 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 23.5294 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 23.5294 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 23.5294 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.3529 | 6 | yes |
| GO:2000026 | regulation of multicellular organismal development | 22.3529 | 4 | yes |
| GO:0034762 | regulation of transmembrane transport | 22.3529 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.3529 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.3529 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.3529 | 6 | no |
| GO:0051094 | positive regulation of developmental process | 21.1765 | 4 | yes |
| GO:2000145 | regulation of cell motility | 21.1765 | 4 | yes |
| GO:0031400 | negative regulation of protein modification process | 21.1765 | 7 | no |
| GO:0043269 | regulation of monoatomic ion transport | 21.1765 | 5 | no |
| GO:0007010 | cytoskeleton organization | 21.1765 | 5 | no |
| GO:0002684 | positive regulation of immune system process | 21.1765 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.1765 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.1765 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.1765 | 4 | yes |
| GO:0030334 | regulation of cell migration | 21.1765 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 21.1765 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 21.1765 | 4 | yes |
| GO:0051336 | regulation of hydrolase activity | 18.8235 | 4 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 18.8235 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 18.8235 | 4 | yes |
| GO:0051046 | regulation of secretion | 17.6471 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 17.6471 | 6 | yes |
| GO:2000147 | positive regulation of cell motility | 16.4706 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 16.4706 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 16.4706 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 16.4706 | 4 | yes |
| GO:0051223 | regulation of protein transport | 15.2941 | 5 | yes |
| GO:0060284 | regulation of cell development | 15.2941 | 5 | yes |
| GO:1903530 | regulation of secretion by cell | 15.2941 | 4 | yes |
| GO:0007264 | small GTPase-mediated signal transduction | 15.2941 | 5 | yes |
| GO:0043085 | positive regulation of catalytic activity | 15.2941 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 15.2941 | 5 | yes |
| GO:0050807 | regulation of synapse organization | 14.1176 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 14.1176 | 5 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 14.1176 | 7 | yes |
| GO:0072657 | protein localization to membrane | 14.1176 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 14.1176 | 4 | yes |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 12.9412 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 12.9412 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 12.9412 | 7 | yes |
| GO:0014070 | response to organic cyclic compound | 12.9412 | 4 | yes |
| GO:0031346 | positive regulation of cell projection organization | 12.9412 | 6 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 11.7647 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 11.7647 | 6 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 11.7647 | 5 | yes |
| GO:0050767 | regulation of neurogenesis | 11.7647 | 6 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 10.5882 | 4 | yes |
| GO:0043087 | regulation of GTPase activity | 10.5882 | 5 | yes |
| GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 9.4118 | 5 | yes |
| GO:0022604 | regulation of cell morphogenesis | 9.4118 | 5 | yes |
| GO:0043393 | regulation of protein binding | 9.4118 | 4 | yes |
| GO:0051099 | positive regulation of binding | 8.2353 | 4 | yes |
| GO:0051962 | positive regulation of nervous system development | 8.2353 | 5 | yes |
| GO:0099175 | regulation of postsynapse organization | 8.2353 | 6 | yes |
| GO:0010976 | positive regulation of neuron projection development | 8.2353 | 7 | yes |
| GO:0016055 | Wnt signaling pathway | 8.2353 | 4 | yes |
| GO:0043547 | positive regulation of GTPase activity | 8.2353 | 6 | yes |
| GO:0045664 | regulation of neuron differentiation | 8.2353 | 5 | yes |
| GO:0050769 | positive regulation of neurogenesis | 8.2353 | 6 | yes |
| GO:0050773 | regulation of dendrite development | 7.0588 | 4 | yes |
| GO:0016601 | Rac protein signal transduction | 7.0588 | 6 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 7.0588 | 5 | yes |
| GO:0032092 | positive regulation of protein binding | 7.0588 | 5 | yes |
| GO:0046883 | regulation of hormone secretion | 7.0588 | 4 | yes |
| GO:0050708 | regulation of protein secretion | 7.0588 | 5 | yes |
| GO:0050770 | regulation of axonogenesis | 5.8824 | 5 | yes |
| GO:0050796 | regulation of insulin secretion | 5.8824 | 6 | yes |
| GO:0050920 | regulation of chemotaxis | 5.8824 | 4 | yes |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 5.8824 | 6 | yes |
| GO:0090087 | regulation of peptide transport | 5.8824 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 5.8824 | 5 | yes |
| GO:0099159 | regulation of modification of postsynaptic structure | 5.8824 | 7 | yes |
| GO:1905244 | regulation of modification of synaptic structure | 5.8824 | 6 | yes |
| GO:1990138 | neuron projection extension | 5.8824 | 4 | yes |
| GO:0002791 | regulation of peptide secretion | 5.8824 | 6 | yes |
| GO:0007160 | cell-matrix adhesion | 5.8824 | 4 | yes |
| GO:0035567 | non-canonical Wnt signaling pathway | 5.8824 | 5 | yes |
| GO:0043279 | response to alkaloid | 5.8824 | 5 | yes |
| GO:0048013 | ephrin receptor signaling pathway | 5.8824 | 6 | yes |
| GO:0048814 | regulation of dendrite morphogenesis | 5.8824 | 5 | yes |
| GO:0050921 | positive regulation of chemotaxis | 4.7059 | 5 | yes |
| GO:0060998 | regulation of dendritic spine development | 4.7059 | 4 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 4.7059 | 5 | yes |
| GO:0090630 | activation of GTPase activity | 4.7059 | 7 | yes |
| GO:2000050 | regulation of non-canonical Wnt signaling pathway | 4.7059 | 6 | yes |
| GO:0050772 | positive regulation of axonogenesis | 3.5294 | 6 | yes |
| GO:0050775 | positive regulation of dendrite morphogenesis | 3.5294 | 6 | yes |
| GO:0060999 | positive regulation of dendritic spine development | 3.5294 | 5 | yes |
| GO:0061003 | positive regulation of dendritic spine morphogenesis | 3.5294 | 6 | yes |
| GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus | 3.5294 | 7 | yes |
| GO:1900147 | regulation of Schwann cell migration | 3.5294 | 7 | yes |
| GO:1903975 | regulation of glial cell migration | 3.5294 | 6 | yes |
| GO:1905274 | regulation of modification of postsynaptic actin cytoskeleton | 3.5294 | 8 | yes |
| GO:0010717 | regulation of epithelial to mesenchymal transition | 3.5294 | 5 | yes |
| GO:0010770 | positive regulation of cell morphogenesis | 3.5294 | 6 | yes |
| GO:1900149 | positive regulation of Schwann cell migration | 2.3529 | 8 | yes |
| GO:1903977 | positive regulation of glial cell migration | 2.3529 | 7 | yes |
| GO:1904266 | regulation of Schwann cell chemotaxis | 2.3529 | 5 | yes |
| GO:1904268 | positive regulation of Schwann cell chemotaxis | 2.3529 | 6 | yes |
| GO:1904338 | regulation of dopaminergic neuron differentiation | 2.3529 | 6 | yes |
| GO:0003300 | cardiac muscle hypertrophy | 2.3529 | 6 | yes |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition | 2.3529 | 5 | yes |
| GO:0014896 | muscle hypertrophy | 2.3529 | 4 | yes |
| GO:0014897 | striated muscle hypertrophy | 2.3529 | 5 | yes |
| GO:0042220 | response to cocaine | 2.3529 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OSBL1_HUMAN | [view interactions] | Low throughput | no | yes |
| ZKSC4_HUMAN | [view interactions] | Low throughput | no | yes |
| FND3B_HUMAN | [view interactions] | Low throughput | no | no |
| SRSF5_HUMAN | [view interactions] | Low throughput | no | yes |
| SYCP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SETB1_HUMAN | [view interactions] | Low throughput | no | yes |
| JIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| JIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| ANK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ANK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NSD2_HUMAN | [view interactions] | Low throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1A_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TIAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD44_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SDC1_HUMAN | [view interactions] | Low throughput | no | no |
| CNTP4_HUMAN | [view interactions] | Low throughput | no | no |
| SDC3_HUMAN | [view interactions] | Low throughput | no | yes |
| SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
| SDC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DAAM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN133_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT44_HUMAN | [view interactions] | High throughput | no | yes |
| NRBP_HUMAN | [view interactions] | High throughput | no | yes |
| ZN793_HUMAN | [view interactions] | High throughput | no | no |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRP5_HUMAN | [view interactions] | High throughput | no | no |
| ENPP5_HUMAN | [view interactions] | High throughput | no | yes |
| CHD9_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRIT1_HUMAN | [view interactions] | High throughput | no | no |
| MBD1_HUMAN | [view interactions] | High throughput | no | yes |
| DZIP1_HUMAN | [view interactions] | High throughput | no | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAAF9_HUMAN | [view interactions] | High throughput | no | yes |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| ZNF34_HUMAN | [view interactions] | High throughput | no | no |
| SGTA_HUMAN | [view interactions] | High throughput | no | yes |
| ZN350_HUMAN | [view interactions] | High throughput | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCLK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF1C_HUMAN | [view interactions] | High throughput | no | yes |
| MAST3_HUMAN | [view interactions] | High throughput | no | yes |
| SRGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
| NADK_HUMAN | [view interactions] | High throughput | no | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| IF4E2_HUMAN | [view interactions] | High throughput | no | no |
| MPIP2_HUMAN | [view interactions] | High throughput | no | no |
| MPIP3_HUMAN | [view interactions] | High throughput | no | yes |
| CDK16_HUMAN | [view interactions] | High throughput | no | yes |
| CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN638_HUMAN | [view interactions] | High throughput | no | yes |
| M3K21_HUMAN | [view interactions] | High throughput | no | yes |
| SPD2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEN4C_HUMAN | [view interactions] | High throughput | no | yes |
| PHLB2_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| DEN1A_HUMAN | [view interactions] | High throughput | no | no |
| SIN1_HUMAN | [view interactions] | High throughput | no | yes |
| RTKN_HUMAN | [view interactions] | High throughput | no | yes |
| INP5E_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1H_HUMAN | [view interactions] | High throughput | no | yes |
| AN34A_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
| F110B_HUMAN | [view interactions] | High throughput | no | yes |
| SRS12_HUMAN | [view interactions] | High throughput | no | no |
| MAGI1_HUMAN | [view interactions] | High throughput | no | no |
| TESK2_HUMAN | [view interactions] | High throughput | no | yes |
| F110A_HUMAN | [view interactions] | High throughput | no | yes |
| KI13B_HUMAN | [view interactions] | High throughput | no | yes |
| FA53C_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CING_HUMAN | [view interactions] | High throughput | no | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP21_HUMAN | [view interactions] | High throughput | no | no |
| ZBT21_HUMAN | [view interactions] | High throughput | no | yes |
| AGAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| CBP_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| KBTB6_HUMAN | [view interactions] | High throughput | no | yes |
| KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| P5CS_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNT1_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH2_HUMAN | [view interactions] | High throughput | no | yes |
| CTSL2_HUMAN | [view interactions] | High throughput | no | no |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| WDR33_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| PIP_HUMAN | [view interactions] | High throughput | no | no |
| ABTB2_HUMAN | [view interactions] | High throughput | no | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| SKP2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| PHKG2_HUMAN | [view interactions] | High throughput | no | no |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYDC_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MAZ_HUMAN | [view interactions] | High throughput | no | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| IGHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGHM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NASP_HUMAN | [view interactions] | High throughput | no | yes |
| H33_HUMAN | [view interactions] | High throughput | no | yes |
| ZHANG_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRYAB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
| RYR3_HUMAN | [view interactions] | High throughput | no | no |
| DPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHGA_HUMAN | [view interactions] | High throughput | no | yes |
| SENP6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBC23_HUMAN | [view interactions] | High throughput | no | yes |
| CCD15_HUMAN | [view interactions] | High throughput | no | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| TOP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN292_HUMAN | [view interactions] | High throughput | no | yes |
| ZN558_HUMAN | [view interactions] | High throughput | no | no |
| TMED4_HUMAN | [view interactions] | High throughput | no | yes |
| ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABTB3_HUMAN | [view interactions] | High throughput | no | no |
| RAB6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX10_HUMAN | [view interactions] | High throughput | no | yes |
| NDF2_HUMAN | [view interactions] | High throughput | no | no |