DHE3_HUMAN
Evidence for PS localization
Functions
Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed, PubMed, PubMed, PubMed). Plays a role in insulin homeostasis (PubMed, PubMed). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DHE3_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 29.5455 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 29.5455 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.5455 | 4 | yes |
| GO:0003723 | RNA binding | 29.5455 | 4 | no |
| GO:0005524 | ATP binding | 22.7273 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.7273 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.7273 | 5 | yes |
| GO:0046872 | metal ion binding | 21.5909 | 4 | no |
| GO:0051287 | NAD binding | 10.2273 | 4 | yes |
| GO:0005525 | GTP binding | 9.0909 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 9.0909 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 9.0909 | 5 | yes |
| GO:0016597 | amino acid binding | 3.4091 | 4 | yes |
| GO:0043531 | ADP binding | 3.4091 | 4 | yes |
| GO:0070403 | NAD+ binding | 3.4091 | 4 | yes |
| GO:0004352 | glutamate dehydrogenase (NAD+) activity | 2.2727 | 6 | yes |
| GO:0004353 | glutamate dehydrogenase [NAD(P)+] activity | 2.2727 | 5 | yes |
| GO:0004354 | glutamate dehydrogenase (NADP+) activity | 2.2727 | 6 | yes |
| GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | 2.2727 | 4 | yes |
| GO:0070728 | leucine binding | 2.2727 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DHE3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 48.8636 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 46.5909 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 42.0455 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 40.9091 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.9091 | 4 | no |
| GO:0010646 | regulation of cell communication | 40.9091 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 39.7727 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.6364 | 4 | no |
| GO:0022607 | cellular component assembly | 34.0909 | 4 | no |
| GO:0009966 | regulation of signal transduction | 34.0909 | 4 | no |
| GO:0010468 | regulation of gene expression | 32.9545 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 32.9545 | 4 | no |
| GO:0006996 | organelle organization | 30.6818 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 30.6818 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.6818 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.6818 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 30.6818 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.5455 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 29.5455 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 29.5455 | 5 | no |
| GO:0010941 | regulation of cell death | 28.4091 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.4091 | 5 | no |
| GO:0019752 | carboxylic acid metabolic process | 28.4091 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 28.4091 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.1364 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.8636 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.8636 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.8636 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.8636 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.7273 | 6 | no |
| GO:0071702 | organic substance transport | 22.7273 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.7273 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.7273 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.7273 | 6 | no |
| GO:0043412 | macromolecule modification | 22.7273 | 4 | no |
| GO:0031399 | regulation of protein modification process | 21.5909 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 21.5909 | 7 | no |
| GO:0036211 | protein modification process | 21.5909 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.4545 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 20.4545 | 5 | no |
| GO:0071705 | nitrogen compound transport | 20.4545 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.4545 | 4 | no |
| GO:0071310 | cellular response to organic substance | 20.4545 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 20.4545 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 20.4545 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 19.3182 | 4 | yes |
| GO:0051049 | regulation of transport | 19.3182 | 4 | yes |
| GO:0032880 | regulation of protein localization | 17.0455 | 5 | yes |
| GO:0043648 | dicarboxylic acid metabolic process | 17.0455 | 6 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 15.9091 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 14.7727 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 14.7727 | 5 | yes |
| GO:0016054 | organic acid catabolic process | 14.7727 | 4 | yes |
| GO:0046395 | carboxylic acid catabolic process | 14.7727 | 5 | yes |
| GO:0009063 | cellular amino acid catabolic process | 13.6364 | 4 | yes |
| GO:0051050 | positive regulation of transport | 12.5000 | 4 | yes |
| GO:1901605 | alpha-amino acid metabolic process | 12.5000 | 4 | yes |
| GO:1901606 | alpha-amino acid catabolic process | 12.5000 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 11.3636 | 6 | yes |
| GO:0016053 | organic acid biosynthetic process | 11.3636 | 4 | yes |
| GO:0046394 | carboxylic acid biosynthetic process | 11.3636 | 5 | yes |
| GO:0051223 | regulation of protein transport | 10.2273 | 5 | yes |
| GO:0006536 | glutamate metabolic process | 10.2273 | 6 | yes |
| GO:0009064 | glutamine family amino acid metabolic process | 10.2273 | 5 | yes |
| GO:0009065 | glutamine family amino acid catabolic process | 10.2273 | 6 | yes |
| GO:0051222 | positive regulation of protein transport | 9.0909 | 5 | yes |
| GO:0072350 | tricarboxylic acid metabolic process | 9.0909 | 6 | yes |
| GO:1903530 | regulation of secretion by cell | 9.0909 | 4 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 9.0909 | 6 | yes |
| GO:0051046 | regulation of secretion | 9.0909 | 5 | yes |
| GO:1901607 | alpha-amino acid biosynthetic process | 7.9545 | 5 | yes |
| GO:0008652 | cellular amino acid biosynthetic process | 7.9545 | 4 | yes |
| GO:1903532 | positive regulation of secretion by cell | 6.8182 | 5 | yes |
| GO:0006538 | glutamate catabolic process | 6.8182 | 5 | yes |
| GO:0021762 | substantia nigra development | 6.8182 | 4 | yes |
| GO:0043649 | dicarboxylic acid catabolic process | 6.8182 | 6 | yes |
| GO:0043650 | dicarboxylic acid biosynthetic process | 6.8182 | 6 | yes |
| GO:0050708 | regulation of protein secretion | 6.8182 | 5 | yes |
| GO:0051047 | positive regulation of secretion | 6.8182 | 5 | yes |
| GO:0006541 | glutamine metabolic process | 5.6818 | 6 | yes |
| GO:0009084 | glutamine family amino acid biosynthetic process | 5.6818 | 6 | yes |
| GO:0050714 | positive regulation of protein secretion | 5.6818 | 6 | yes |
| GO:0090087 | regulation of peptide transport | 4.5455 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 4.5455 | 5 | yes |
| GO:0002791 | regulation of peptide secretion | 4.5455 | 6 | yes |
| GO:0006537 | glutamate biosynthetic process | 4.5455 | 7 | yes |
| GO:0046883 | regulation of hormone secretion | 4.5455 | 4 | yes |
| GO:0050796 | regulation of insulin secretion | 4.5455 | 6 | yes |
| GO:0090277 | positive regulation of peptide hormone secretion | 3.4091 | 6 | yes |
| GO:0002793 | positive regulation of peptide secretion | 3.4091 | 6 | yes |
| GO:0032024 | positive regulation of insulin secretion | 3.4091 | 7 | yes |
| GO:0046887 | positive regulation of hormone secretion | 3.4091 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DHE3_HUMAN |
|---|---|---|---|---|
| DOID:700 | mitochondrial metabolism disease | 3.4091 | 3 | no |
| DOID:0050155 | sensory system disease | 2.2727 | 3 | no |
| DOID:10584 | retinitis pigmentosa | 2.2727 | 7 | no |
| DOID:5614 | eye disease | 2.2727 | 4 | no |
| DOID:8466 | retinal degeneration | 2.2727 | 6 | no |
| DOID:9799 | eye degenerative disease | 2.2727 | 5 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.2727 | 6 | no |
| DOID:1289 | neurodegenerative disease | 2.2727 | 4 | no |
| DOID:231 | motor neuron disease | 2.2727 | 5 | no |
| DOID:331 | central nervous system disease | 2.2727 | 3 | no |
| DOID:440 | neuromuscular disease | 2.2727 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.2727 | 3 | no |
| DOID:870 | neuropathy | 2.2727 | 4 | no |
| DOID:0060286 | combined oxidative phosphorylation deficiency | 2.2727 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GCKR_HUMAN | [view interactions] | Low throughput | no | no |
| HXK4_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF13_HUMAN | [view interactions] | Low throughput | no | yes |
| RN213_HUMAN | [view interactions] | Low throughput | no | yes |
| SIR4_HUMAN | [view interactions] | Low throughput | no | yes |
| DHE3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| STA5A_HUMAN | [view interactions] | High throughput | no | no |
| M3K1_HUMAN | [view interactions] | High throughput | no | yes |
| M3K14_HUMAN | [view interactions] | High throughput | no | yes |
| CDK5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F6_HUMAN | [view interactions] | High throughput | no | no |
| LMBL1_HUMAN | [view interactions] | High throughput | no | no |
| TFDP1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB32_HUMAN | [view interactions] | High throughput | no | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM4C_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| DDR2_HUMAN | [view interactions] | High throughput | no | no |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| LSM1_HUMAN | [view interactions] | High throughput | no | no |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCP2_HUMAN | [view interactions] | High throughput | no | yes |
| KLH29_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CRBN_HUMAN | [view interactions] | High throughput | no | yes |
| NKX21_HUMAN | [view interactions] | High throughput | no | no |
| HYPK_HUMAN | [view interactions] | High throughput | no | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| PTN22_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPR2_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| SIR3_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG30_HUMAN | [view interactions] | High throughput | no | no |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF5_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF7_HUMAN | [view interactions] | High throughput | no | yes |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
| NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI42A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| ATG4B_HUMAN | [view interactions] | High throughput | no | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| IF2G_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| ENY2_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN5_HUMAN | [view interactions] | High throughput | no | no |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CND2_HUMAN | [view interactions] | High throughput | no | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB10_HUMAN | [view interactions] | High throughput | no | no |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| TOP2A_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYSM_HUMAN | [view interactions] | High throughput | no | yes |
| NNTM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRXR2_HUMAN | [view interactions] | High throughput | no | yes |
| MRM1_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| GRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| AUHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CQ080_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| CH082_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| RRF2M_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCU_HUMAN | [view interactions] | High throughput | no | yes |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| RRFM_HUMAN | [view interactions] | High throughput | no | yes |
| MTG2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| OTC_HUMAN | [view interactions] | High throughput | no | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| MPPB_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| EFTS_HUMAN | [view interactions] | High throughput | no | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| SYAM_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| ASGR2_HUMAN | [view interactions] | High throughput | no | no |
| CRP_HUMAN | [view interactions] | High throughput | no | no |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| VTNC_HUMAN | [view interactions] | High throughput | no | no |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| PAR6A_HUMAN | [view interactions] | High throughput | no | yes |
| GORS1_HUMAN | [view interactions] | High throughput | no | yes |
| KLH22_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC8_HUMAN | [view interactions] | High throughput | no | no |
| DHE4_HUMAN | [view interactions] | High throughput | no | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COQ6_HUMAN | [view interactions] | High throughput | no | yes |
| COQ7_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| PPE1_HUMAN | [view interactions] | High throughput | no | no |
| DUS16_HUMAN | [view interactions] | High throughput | no | yes |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHF_HUMAN | [view interactions] | High throughput | no | no |
| MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| TESK1_HUMAN | [view interactions] | High throughput | no | no |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPSH2_HUMAN | [view interactions] | High throughput | no | no |
| STK33_HUMAN | [view interactions] | High throughput | no | no |
| NRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| EPHB6_HUMAN | [view interactions] | High throughput | no | no |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCE2_HUMAN | [view interactions] | Computational | no | yes |
| G6PD_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AATM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NAGS_HUMAN | [view interactions] | Computational | no | no |
| AL4A1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HCDH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNDP1_HUMAN | [view interactions] | Computational | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLNA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIPK3_HUMAN | [view interactions] | Computational | no | no |
| GCST_HUMAN | [view interactions] | Computational | no | yes |
| G6PE_HUMAN | [view interactions] | Computational | no | yes |
| GGT1_HUMAN | [view interactions] | Computational | no | no |
| ALAT1_HUMAN | [view interactions] | Computational | no | no |
| GATM_HUMAN | [view interactions] | Computational | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AATC2_HUMAN | [view interactions] | Computational | no | no |
| GLSL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P5CS_HUMAN | [view interactions] | Computational | no | yes |
| GGT7_HUMAN | [view interactions] | Computational | no | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IDH3B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| L2HDH_HUMAN | [view interactions] | Computational | no | yes |
| PYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NIT2_HUMAN | [view interactions] | Computational | no | yes |
| IDHC_HUMAN | [view interactions] | Computational | no | no |
| GGT5_HUMAN | [view interactions] | Computational | no | yes |
| ODO1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SYEM_HUMAN | [view interactions] | Computational | no | yes |
| PCKGM_HUMAN | [view interactions] | Computational | no | no |
| SYEP_HUMAN | [view interactions] | Computational | no | yes |
| FTCD_HUMAN | [view interactions] | Computational | no | no |
| AATC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CPSM_HUMAN | [view interactions] | Computational | no | no |
| ACY2_HUMAN | [view interactions] | Computational | no | no |
| GCSH_HUMAN | [view interactions] | Computational | no | yes |
| CRNS1_HUMAN | [view interactions] | Computational | no | no |
| OGDHL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLSK_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ALAT2_HUMAN | [view interactions] | Computational | no | yes |
| GCSP_HUMAN | [view interactions] | Computational | no | yes |
| PCKGC_HUMAN | [view interactions] | Computational | no | no |
| IDH3G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GSH0_HUMAN | [view interactions] | Computational | no | yes |
| OPLA_HUMAN | [view interactions] | Computational | no | no |