PI42A_HUMAN
Evidence for PS localization
Functions
Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) (PubMed, PubMed). Has both ATP- and GTP-dependent kinase activities (PubMed). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2 (PubMed). May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation . Required for lysosome-peroxisome membrane contacts and intracellular cholesterol transport through modulating peroxisomal PtdIns(4,5)P2 level (PubMed). In collaboration with PIP4K2B, has a role in mediating autophagy in times of nutrient stress . Required for autophagosome-lysosome fusion and the regulation of cellular lipid metabolism (PubMed). May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size . Negatively regulates insulin signaling through a catalytic-independent mechanism (PubMed). PIP4Ks interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PI42A_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 24.5283 | 4 | yes |
| GO:0000166 | nucleotide binding | 22.6415 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 22.6415 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 22.6415 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.6415 | 4 | yes |
| GO:0003723 | RNA binding | 20.7547 | 4 | no |
| GO:0005524 | ATP binding | 16.9811 | 5 | yes |
| GO:0016301 | kinase activity | 16.9811 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 16.9811 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 16.9811 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 16.9811 | 5 | yes |
| GO:0042803 | protein homodimerization activity | 9.4340 | 4 | yes |
| GO:0001727 | lipid kinase activity | 5.6604 | 5 | yes |
| GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity | 5.6604 | 6 | yes |
| GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity | 5.6604 | 6 | yes |
| GO:0052742 | phosphatidylinositol kinase activity | 5.6604 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PI42A_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 58.4906 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.9434 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.9434 | 4 | yes |
| GO:0010646 | regulation of cell communication | 50.9434 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 45.2830 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 41.5094 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 39.6226 | 4 | yes |
| GO:0008104 | protein localization | 39.6226 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 37.7358 | 4 | no |
| GO:0006996 | organelle organization | 37.7358 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 37.7358 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 35.8491 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.8491 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.8491 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.8491 | 5 | no |
| GO:0051049 | regulation of transport | 35.8491 | 4 | no |
| GO:0022607 | cellular component assembly | 35.8491 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.9623 | 5 | yes |
| GO:0071702 | organic substance transport | 33.9623 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 33.9623 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.0755 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 32.0755 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 32.0755 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 30.1887 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 28.3019 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 28.3019 | 5 | no |
| GO:0071705 | nitrogen compound transport | 26.4151 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.4151 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.4151 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.4151 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 26.4151 | 5 | no |
| GO:0009894 | regulation of catabolic process | 26.4151 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 26.4151 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 26.4151 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 26.4151 | 4 | yes |
| GO:0015031 | protein transport | 24.5283 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.5283 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.6415 | 4 | yes |
| GO:0036211 | protein modification process | 22.6415 | 4 | no |
| GO:0043412 | macromolecule modification | 22.6415 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.7547 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 20.7547 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 20.7547 | 4 | no |
| GO:0051726 | regulation of cell cycle | 20.7547 | 4 | no |
| GO:0030030 | cell projection organization | 20.7547 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 20.7547 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.7547 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.7547 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.7547 | 6 | no |
| GO:0061024 | membrane organization | 18.8679 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 18.8679 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 16.9811 | 5 | yes |
| GO:0010506 | regulation of autophagy | 16.9811 | 6 | yes |
| GO:0016310 | phosphorylation | 16.9811 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 15.0943 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 15.0943 | 6 | yes |
| GO:0016050 | vesicle organization | 15.0943 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 13.2075 | 5 | yes |
| GO:0016241 | regulation of macroautophagy | 9.4340 | 7 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 7.5472 | 6 | yes |
| GO:0046626 | regulation of insulin receptor signaling pathway | 7.5472 | 5 | yes |
| GO:0046627 | negative regulation of insulin receptor signaling pathway | 7.5472 | 6 | yes |
| GO:0048284 | organelle fusion | 7.5472 | 5 | yes |
| GO:0061025 | membrane fusion | 7.5472 | 5 | yes |
| GO:0090174 | organelle membrane fusion | 7.5472 | 6 | yes |
| GO:1900076 | regulation of cellular response to insulin stimulus | 7.5472 | 4 | yes |
| GO:1900077 | negative regulation of cellular response to insulin stimulus | 7.5472 | 5 | yes |
| GO:0006869 | lipid transport | 7.5472 | 5 | yes |
| GO:0006906 | vesicle fusion | 7.5472 | 6 | yes |
| GO:0010508 | positive regulation of autophagy | 7.5472 | 7 | yes |
| GO:0015850 | organic hydroxy compound transport | 7.5472 | 5 | yes |
| GO:0044088 | regulation of vacuole organization | 5.6604 | 6 | yes |
| GO:0044090 | positive regulation of vacuole organization | 5.6604 | 7 | yes |
| GO:0045017 | glycerolipid biosynthetic process | 5.6604 | 4 | yes |
| GO:0046474 | glycerophospholipid biosynthetic process | 5.6604 | 5 | yes |
| GO:0046486 | glycerolipid metabolic process | 5.6604 | 4 | yes |
| GO:0046488 | phosphatidylinositol metabolic process | 5.6604 | 6 | yes |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | 5.6604 | 7 | yes |
| GO:0061909 | autophagosome-lysosome fusion | 5.6604 | 7 | yes |
| GO:0090407 | organophosphate biosynthetic process | 5.6604 | 4 | yes |
| GO:1902115 | regulation of organelle assembly | 5.6604 | 5 | yes |
| GO:1902117 | positive regulation of organelle assembly | 5.6604 | 6 | yes |
| GO:1902633 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process | 5.6604 | 7 | yes |
| GO:1902635 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process | 5.6604 | 8 | yes |
| GO:2000785 | regulation of autophagosome assembly | 5.6604 | 6 | yes |
| GO:2000786 | positive regulation of autophagosome assembly | 5.6604 | 7 | yes |
| GO:0006644 | phospholipid metabolic process | 5.6604 | 4 | yes |
| GO:0006650 | glycerophospholipid metabolic process | 5.6604 | 5 | yes |
| GO:0006661 | phosphatidylinositol biosynthetic process | 5.6604 | 6 | yes |
| GO:0008610 | lipid biosynthetic process | 5.6604 | 4 | yes |
| GO:0008654 | phospholipid biosynthetic process | 5.6604 | 5 | yes |
| GO:0015918 | sterol transport | 5.6604 | 6 | yes |
| GO:0016239 | positive regulation of macroautophagy | 5.6604 | 8 | yes |
| GO:0016482 | cytosolic transport | 5.6604 | 4 | yes |
| GO:0030301 | cholesterol transport | 5.6604 | 7 | yes |
| GO:0032365 | intracellular lipid transport | 3.7736 | 4 | yes |
| GO:0032366 | intracellular sterol transport | 3.7736 | 5 | yes |
| GO:0032367 | intracellular cholesterol transport | 3.7736 | 6 | yes |
| GO:0035855 | megakaryocyte development | 3.7736 | 6 | yes |
| GO:0061515 | myeloid cell development | 3.7736 | 5 | yes |
| GO:0030097 | hemopoiesis | 3.7736 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KS6B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PI42A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTM1_HUMAN | [view interactions] | Low throughput | no | yes |
| SRSF8_HUMAN | [view interactions] | High throughput | no | yes |
| RHG22_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCOF_HUMAN | [view interactions] | High throughput | no | yes |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |
| ARK2N_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
| CHD8_HUMAN | [view interactions] | High throughput | no | no |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| RFIP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYAR_HUMAN | [view interactions] | High throughput | no | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMA16_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYY1_HUMAN | [view interactions] | High throughput | no | yes |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| RS21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KNOP1_HUMAN | [view interactions] | High throughput | no | yes |
| SLTM_HUMAN | [view interactions] | High throughput | no | yes |
| MMTA2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
| PR38B_HUMAN | [view interactions] | High throughput | no | no |
| DDX56_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF7_HUMAN | [view interactions] | High throughput | no | yes |
| HXA5_HUMAN | [view interactions] | High throughput | no | no |
| ELOA1_HUMAN | [view interactions] | High throughput | no | yes |
| PHF6_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF5_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| PRPF3_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| CI114_HUMAN | [view interactions] | High throughput | no | yes |
| CAH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUSAP_HUMAN | [view interactions] | High throughput | no | no |
| FA98A_HUMAN | [view interactions] | High throughput | no | no |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
| TAF2_HUMAN | [view interactions] | High throughput | no | no |
| DHE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
| SPR2E_HUMAN | [view interactions] | High throughput | no | no |
| NUFP2_HUMAN | [view interactions] | High throughput | no | no |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| SLIT2_HUMAN | [view interactions] | High throughput | no | no |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| CD6_HUMAN | [view interactions] | High throughput | no | no |
| ZCH10_HUMAN | [view interactions] | High throughput | no | yes |
| MADD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC85A_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| ATG4C_HUMAN | [view interactions] | High throughput | no | yes |
| MAX_HUMAN | [view interactions] | High throughput | no | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3K_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| KC1AL_HUMAN | [view interactions] | High throughput | no | no |
| CSK23_HUMAN | [view interactions] | High throughput | no | no |
| RIOK2_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX23_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VTI1A_HUMAN | [view interactions] | High throughput | no | yes |
| AP3S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAP26_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIM8B_HUMAN | [view interactions] | High throughput | no | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC5_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| EH1L1_HUMAN | [view interactions] | High throughput | no | yes |
| IPO9_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| AFF1_HUMAN | [view interactions] | High throughput | no | no |
| AP3B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELL2_HUMAN | [view interactions] | High throughput | no | no |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNT1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CAPON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| AF9_HUMAN | [view interactions] | High throughput | no | yes |
| ELL_HUMAN | [view interactions] | High throughput | no | no |
| PI42B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENL_HUMAN | [view interactions] | High throughput | no | yes |
| PPIG_HUMAN | [view interactions] | High throughput | no | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KANK1_HUMAN | [view interactions] | High throughput | no | yes |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
| EDC4_HUMAN | [view interactions] | High throughput | no | yes |
| RFWD3_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3B_HUMAN | [view interactions] | High throughput | no | no |
| STRAA_HUMAN | [view interactions] | High throughput | no | yes |
| SELH_HUMAN | [view interactions] | High throughput | no | yes |
| PLCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NKAP_HUMAN | [view interactions] | High throughput | no | yes |
| PNISR_HUMAN | [view interactions] | High throughput | no | yes |
| RTF1_HUMAN | [view interactions] | High throughput | no | yes |
| C102A_HUMAN | [view interactions] | High throughput | no | yes |
| CSTOS_HUMAN | [view interactions] | High throughput | no | yes |
| EAF2_HUMAN | [view interactions] | High throughput | no | yes |
| NAF1_HUMAN | [view interactions] | High throughput | no | yes |
| MINT_HUMAN | [view interactions] | High throughput | no | yes |
| SETD2_HUMAN | [view interactions] | High throughput | no | yes |
| PININ_HUMAN | [view interactions] | High throughput | no | yes |
| ELL3_HUMAN | [view interactions] | High throughput | no | yes |
| GPBL1_HUMAN | [view interactions] | High throughput | no | yes |
| CWC22_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| AFF4_HUMAN | [view interactions] | High throughput | no | yes |
| GPTC8_HUMAN | [view interactions] | High throughput | no | yes |
| ACINU_HUMAN | [view interactions] | High throughput | no | yes |
| SET1B_HUMAN | [view interactions] | High throughput | no | yes |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| DIP2C_HUMAN | [view interactions] | High throughput | no | yes |
| AP3M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
| EAF1_HUMAN | [view interactions] | High throughput | no | yes |
| NEMP1_HUMAN | [view interactions] | High throughput | no | no |
| PRIC3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN428_HUMAN | [view interactions] | High throughput | no | yes |
| SIAT1_HUMAN | [view interactions] | High throughput | no | no |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| SOST_HUMAN | [view interactions] | High throughput | no | no |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUAK2_HUMAN | [view interactions] | High throughput | no | yes |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GSTK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP100_HUMAN | [view interactions] | High throughput | no | no |
| TP53B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MEIS3_HUMAN | [view interactions] | High throughput | no | no |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P4_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAB2_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| UBF1_HUMAN | [view interactions] | High throughput | no | yes |
| AFF3_HUMAN | [view interactions] | High throughput | no | yes |
| HDGR2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| CHD9_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH3_HUMAN | [view interactions] | High throughput | no | yes |
| GPAM1_HUMAN | [view interactions] | High throughput | no | yes |
| PI51A_HUMAN | [view interactions] | High throughput | no | yes |
| BRPF1_HUMAN | [view interactions] | High throughput | no | yes |
| RNPS1_HUMAN | [view interactions] | High throughput | no | yes |
| LENG8_HUMAN | [view interactions] | High throughput | no | yes |
| PPRC1_HUMAN | [view interactions] | High throughput | no | yes |
| STRAB_HUMAN | [view interactions] | High throughput | no | no |
| IKBL1_HUMAN | [view interactions] | High throughput | no | no |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| CLASR_HUMAN | [view interactions] | High throughput | no | yes |
| JMJD6_HUMAN | [view interactions] | High throughput | no | yes |
| CXXC1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IWS1_HUMAN | [view interactions] | High throughput | no | yes |