PDIA6_HUMAN
Evidence for PS localization
Functions
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PDIA6_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 29.4118 | 4 | no |
| GO:0003723 | RNA binding | 25.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.0588 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0588 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.5882 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 20.5882 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.5882 | 5 | no |
| GO:0015036 | disulfide oxidoreductase activity | 4.4118 | 4 | yes |
| GO:0016864 | intramolecular oxidoreductase activity, transposing S-S bonds | 2.9412 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PDIA6_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.4118 | 4 | no |
| GO:0010646 | regulation of cell communication | 48.5294 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.5882 | 4 | no |
| GO:0009966 | regulation of signal transduction | 45.5882 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.1176 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 42.6471 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.6471 | 4 | no |
| GO:0043412 | macromolecule modification | 41.1765 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 41.1765 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 41.1765 | 4 | no |
| GO:0010468 | regulation of gene expression | 39.7059 | 5 | no |
| GO:0036211 | protein modification process | 39.7059 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.7647 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.2941 | 5 | no |
| GO:0006996 | organelle organization | 33.8235 | 4 | no |
| GO:0022607 | cellular component assembly | 33.8235 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.8235 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 32.3529 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 32.3529 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 30.8824 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 30.8824 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.8824 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.8824 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 30.8824 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.8824 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.8824 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 30.8824 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.4118 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 29.4118 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.4118 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 29.4118 | 5 | no |
| GO:0023057 | negative regulation of signaling | 29.4118 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.4118 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 29.4118 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 29.4118 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 29.4118 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 29.4118 | 5 | no |
| GO:0010941 | regulation of cell death | 29.4118 | 4 | no |
| GO:0033043 | regulation of organelle organization | 27.9412 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 26.4706 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.4706 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.4706 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 26.4706 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.4706 | 5 | no |
| GO:0031399 | regulation of protein modification process | 25.0000 | 6 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
| GO:0009894 | regulation of catabolic process | 23.5294 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 23.5294 | 7 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.5294 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.5294 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 23.5294 | 4 | no |
| GO:0043933 | protein-containing complex organization | 22.0588 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 22.0588 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.0588 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.0588 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.0588 | 6 | no |
| GO:0071310 | cellular response to organic substance | 22.0588 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.0588 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.0588 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 20.5882 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.5882 | 4 | no |
| GO:0045893 | positive regulation of DNA-templated transcription | 20.5882 | 7 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.5882 | 6 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 20.5882 | 6 | no |
| GO:1902680 | positive regulation of RNA biosynthetic process | 20.5882 | 7 | no |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 20.5882 | 8 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.5882 | 6 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PDIA6_HUMAN |
|---|---|---|---|---|
| DOID:0050890 | synucleinopathy | 2.9412 | 5 | no |
| DOID:0060894 | early-onset Parkinsons disease | 2.9412 | 7 | no |
| DOID:1289 | neurodegenerative disease | 2.9412 | 4 | no |
| DOID:14330 | Parkinsons disease | 2.9412 | 6 | no |
| DOID:331 | central nervous system disease | 2.9412 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LEG9_HUMAN | [view interactions] | Low throughput | no | yes |
| PRDX4_HUMAN | [view interactions] | Low throughput | no | yes |
| PIAS1_HUMAN | [view interactions] | Low throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| PI42A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALR_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF5_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| ERN1_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| BACD3_HUMAN | [view interactions] | High throughput | no | yes |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S22A2_HUMAN | [view interactions] | High throughput | no | no |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICLN_HUMAN | [view interactions] | High throughput | no | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NRDC_HUMAN | [view interactions] | High throughput | no | no |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF2AA_HUMAN | [view interactions] | High throughput | no | yes |
| P3H1_HUMAN | [view interactions] | High throughput | no | yes |
| MAT2B_HUMAN | [view interactions] | High throughput | no | yes |
| PCY1A_HUMAN | [view interactions] | High throughput | no | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPD52_HUMAN | [view interactions] | High throughput | no | yes |
| XPO5_HUMAN | [view interactions] | High throughput | no | yes |
| TPD54_HUMAN | [view interactions] | High throughput | no | yes |
| UGDH_HUMAN | [view interactions] | High throughput | no | no |
| ACO13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC3_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN2_HUMAN | [view interactions] | High throughput | no | yes |
| CASP8_HUMAN | [view interactions] | High throughput | no | yes |
| MESD_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD4_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| UBR7_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| UGGG1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
| MATN3_HUMAN | [view interactions] | High throughput | no | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| CALR3_HUMAN | [view interactions] | High throughput | no | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDF1_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| DJB12_HUMAN | [view interactions] | High throughput | no | yes |
| DIK2A_HUMAN | [view interactions] | High throughput | no | yes |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDEM2_HUMAN | [view interactions] | High throughput | no | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| DMXL1_HUMAN | [view interactions] | High throughput | no | yes |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| O51F2_HUMAN | [view interactions] | High throughput | no | no |
| IBP5_HUMAN | [view interactions] | High throughput | no | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN281_HUMAN | [view interactions] | High throughput | no | no |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| ANR45_HUMAN | [view interactions] | High throughput | no | no |
| SLF1_HUMAN | [view interactions] | High throughput | no | no |
| ATG2B_HUMAN | [view interactions] | High throughput | no | no |
| PKHO1_HUMAN | [view interactions] | High throughput | no | no |
| RL37L_HUMAN | [view interactions] | High throughput | no | no |
| GNMT_HUMAN | [view interactions] | High throughput | no | no |
| AAKG2_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM2_HUMAN | [view interactions] | High throughput | no | yes |
| DNHD1_HUMAN | [view interactions] | High throughput | no | no |
| DPEP3_HUMAN | [view interactions] | High throughput | no | no |
| RGS22_HUMAN | [view interactions] | High throughput | no | no |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| BEND3_HUMAN | [view interactions] | High throughput | no | yes |
| CO1A1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA5_HUMAN | [view interactions] | High throughput | no | yes |
| SYT11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK_HUMAN | [view interactions] | High throughput | no | no |
| ERN2_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR14_HUMAN | [view interactions] | High throughput | no | no |
| CD9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGTB_HUMAN | [view interactions] | High throughput | no | yes |
| GET3_HUMAN | [view interactions] | High throughput | no | yes |
| AT132_HUMAN | [view interactions] | High throughput | no | yes |
| MC4R_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| CK068_HUMAN | [view interactions] | High throughput | no | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| JMY_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJB9_HUMAN | [view interactions] | High throughput | no | yes |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| DJC10_HUMAN | [view interactions] | High throughput | no | yes |
| TECT1_HUMAN | [view interactions] | High throughput | no | yes |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| MED20_HUMAN | [view interactions] | High throughput | no | no |
| CLN8_HUMAN | [view interactions] | High throughput | no | no |
| VKOR1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| LIPC_HUMAN | [view interactions] | High throughput | no | no |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| MET23_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| VWA1_HUMAN | [view interactions] | High throughput | no | no |
| PLSI_HUMAN | [view interactions] | High throughput | no | no |
| KLH24_HUMAN | [view interactions] | High throughput | no | no |
| C102A_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| BTBD9_HUMAN | [view interactions] | High throughput | no | yes |
| HNRLL_HUMAN | [view interactions] | High throughput | no | yes |
| ISCA1_HUMAN | [view interactions] | High throughput | no | yes |
| ZHX3_HUMAN | [view interactions] | High throughput | no | no |
| JMJD8_HUMAN | [view interactions] | High throughput | no | no |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| CRBN_HUMAN | [view interactions] | High throughput | no | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| KDM6B_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| KCD15_HUMAN | [view interactions] | High throughput | no | no |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| SCTM1_HUMAN | [view interactions] | High throughput | no | yes |
| PPAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS23_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| FBLN3_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| HM13_HUMAN | [view interactions] | Computational | no | yes |
| XBP1_HUMAN | [view interactions] | Computational | no | no |
| MANF_HUMAN | [view interactions] | Computational | no | yes |
| OST48_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SC11C_HUMAN | [view interactions] | Computational | no | no |
| ERO1A_HUMAN | [view interactions] | Computational | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |