MACF1_HUMAN
Evidence for PS localization
Functions
F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules (PubMed, PubMed). Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex (PubMed). Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane . Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics . Interaction with CAMSAP3 at the minus ends of non-centrosomal microtubules tethers microtubules minus-ends to actin filaments, regulating focal adhesion size and cell migration (PubMed). May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4 (PubMed). Plays a key role in wound healing and epidermal cell migration . Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate microtubule dynamics and polarize hair follicle stem cells . As a regulator of actin and microtubule arrangement and stabilization, it plays an essential role in neurite outgrowth, branching and spine formation during brain development . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 7135 | Cys | Phe | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7186 | Asp | Tyr | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7188 | Cys | Phe | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7188 | Cys | Gly | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MACF1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 25.7576 | 4 | yes |
| GO:0046872 | metal ion binding | 25.7576 | 4 | yes |
| GO:0045296 | cadherin binding | 24.2424 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 24.2424 | 4 | no |
| GO:0019900 | kinase binding | 24.2424 | 4 | no |
| GO:0019901 | protein kinase binding | 24.2424 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.7273 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.7273 | 4 | no |
| GO:0003779 | actin binding | 21.2121 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 21.2121 | 5 | no |
| GO:0015631 | tubulin binding | 19.6970 | 4 | yes |
| GO:0008017 | microtubule binding | 16.6667 | 5 | yes |
| GO:0005509 | calcium ion binding | 9.0909 | 5 | yes |
| GO:0051011 | microtubule minus-end binding | 3.0303 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MACF1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 74.2424 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 68.1818 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 54.5455 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.5455 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.0303 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 53.0303 | 4 | no |
| GO:0022607 | cellular component assembly | 51.5152 | 4 | no |
| GO:0008104 | protein localization | 50.0000 | 4 | yes |
| GO:0006996 | organelle organization | 46.9697 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 46.9697 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.4545 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 45.4545 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 43.9394 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.9394 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 40.9091 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 40.9091 | 5 | no |
| GO:0009966 | regulation of signal transduction | 39.3939 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 37.8788 | 5 | yes |
| GO:0030030 | cell projection organization | 37.8788 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 36.3636 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 36.3636 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 36.3636 | 6 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 34.8485 | 6 | yes |
| GO:0051049 | regulation of transport | 34.8485 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.3333 | 5 | no |
| GO:0007010 | cytoskeleton organization | 31.8182 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 31.8182 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.8182 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 31.8182 | 5 | no |
| GO:0043412 | macromolecule modification | 30.3030 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 30.3030 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 28.7879 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 28.7879 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 28.7879 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 28.7879 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 27.2727 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 27.2727 | 6 | no |
| GO:0036211 | protein modification process | 27.2727 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:0071702 | organic substance transport | 25.7576 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 25.7576 | 6 | no |
| GO:0060341 | regulation of cellular localization | 25.7576 | 4 | no |
| GO:0051050 | positive regulation of transport | 25.7576 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.7576 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 24.2424 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 24.2424 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 24.2424 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 24.2424 | 4 | no |
| GO:0032880 | regulation of protein localization | 24.2424 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 24.2424 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.2424 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.2424 | 5 | no |
| GO:0010975 | regulation of neuron projection development | 22.7273 | 7 | yes |
| GO:0072657 | protein localization to membrane | 22.7273 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 22.7273 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 22.7273 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 22.7273 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.7273 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.7273 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.7273 | 5 | no |
| GO:0034330 | cell junction organization | 22.7273 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 22.7273 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 21.2121 | 4 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 21.2121 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.2121 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.2121 | 5 | no |
| GO:0071310 | cellular response to organic substance | 21.2121 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.2121 | 4 | no |
| GO:0010941 | regulation of cell death | 21.2121 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 19.6970 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 19.6970 | 4 | yes |
| GO:2000145 | regulation of cell motility | 19.6970 | 4 | yes |
| GO:0015031 | protein transport | 18.1818 | 4 | yes |
| GO:0030334 | regulation of cell migration | 18.1818 | 5 | yes |
| GO:0031346 | positive regulation of cell projection organization | 18.1818 | 6 | yes |
| GO:0001558 | regulation of cell growth | 16.6667 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 16.6667 | 5 | yes |
| GO:0048638 | regulation of developmental growth | 16.6667 | 4 | yes |
| GO:0060284 | regulation of cell development | 16.6667 | 5 | yes |
| GO:1990778 | protein localization to cell periphery | 16.6667 | 5 | yes |
| GO:0051960 | regulation of nervous system development | 15.1515 | 5 | yes |
| GO:0022604 | regulation of cell morphogenesis | 13.6364 | 5 | yes |
| GO:0030516 | regulation of axon extension | 13.6364 | 5 | yes |
| GO:0032886 | regulation of microtubule-based process | 13.6364 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 13.6364 | 6 | yes |
| GO:0051962 | positive regulation of nervous system development | 13.6364 | 5 | yes |
| GO:0061387 | regulation of extent of cell growth | 13.6364 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 12.1212 | 6 | yes |
| GO:0050769 | positive regulation of neurogenesis | 12.1212 | 6 | yes |
| GO:0072659 | protein localization to plasma membrane | 12.1212 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 12.1212 | 5 | yes |
| GO:0001952 | regulation of cell-matrix adhesion | 10.6061 | 6 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 10.6061 | 5 | yes |
| GO:0016055 | Wnt signaling pathway | 10.6061 | 5 | yes |
| GO:0045927 | positive regulation of growth | 10.6061 | 4 | yes |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 10.6061 | 4 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 9.0909 | 5 | yes |
| GO:0030307 | positive regulation of cell growth | 9.0909 | 5 | yes |
| GO:0048639 | positive regulation of developmental growth | 9.0909 | 5 | yes |
| GO:0050770 | regulation of axonogenesis | 9.0909 | 5 | yes |
| GO:0010632 | regulation of epithelial cell migration | 7.5758 | 4 | yes |
| GO:0045773 | positive regulation of axon extension | 7.5758 | 6 | yes |
| GO:0048193 | Golgi vesicle transport | 7.5758 | 5 | yes |
| GO:0050772 | positive regulation of axonogenesis | 7.5758 | 6 | yes |
| GO:0051893 | regulation of focal adhesion assembly | 7.5758 | 7 | yes |
| GO:0090109 | regulation of cell-substrate junction assembly | 7.5758 | 6 | yes |
| GO:0150116 | regulation of cell-substrate junction organization | 7.5758 | 5 | yes |
| GO:0006892 | post-Golgi vesicle-mediated transport | 6.0606 | 6 | yes |
| GO:0030177 | positive regulation of Wnt signaling pathway | 6.0606 | 6 | yes |
| GO:0090150 | establishment of protein localization to membrane | 6.0606 | 4 | yes |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 6.0606 | 4 | yes |
| GO:0006893 | Golgi to plasma membrane transport | 4.5455 | 5 | yes |
| GO:0150011 | regulation of neuron projection arborization | 4.5455 | 6 | yes |
| GO:0042060 | wound healing | 3.0303 | 4 | yes |
| GO:0043001 | Golgi to plasma membrane protein transport | 3.0303 | 5 | yes |
| GO:0061951 | establishment of protein localization to plasma membrane | 3.0303 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MACF1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 3.0303 | 3 | no |
| DOID:0050453 | lissencephaly | 3.0303 | 3 | yes |
| DOID:0112228 | lissencephaly 9 with complex brainstem malformation | 3.0303 | 4 | yes |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UBP14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MACF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| TTC29_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAXX_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1107_HUMAN | [view interactions] | High throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT2_HUMAN | [view interactions] | High throughput | no | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| WIPI2_HUMAN | [view interactions] | High throughput | no | yes |
| BATF3_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISCA1_HUMAN | [view interactions] | High throughput | no | yes |
| C2C4B_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| RSMB_HUMAN | [view interactions] | High throughput | no | yes |
| RU1C_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD5_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKIL_HUMAN | [view interactions] | High throughput | no | yes |
| MCAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ID2_HUMAN | [view interactions] | High throughput | no | no |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| ALX3_HUMAN | [view interactions] | High throughput | no | no |
| AMERL_HUMAN | [view interactions] | High throughput | no | no |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H33_HUMAN | [view interactions] | High throughput | no | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MK09_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| CHP3_HUMAN | [view interactions] | High throughput | no | yes |
| ERR1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| NRCAM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NRX1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLXD1_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRX2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TNG6_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP4_HUMAN | [view interactions] | High throughput | no | no |
| ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEN1_HUMAN | [view interactions] | High throughput | no | no |
| FHL1_HUMAN | [view interactions] | High throughput | no | no |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA4_HUMAN | [view interactions] | Computational | no | yes |
| CAMP3_HUMAN | [view interactions] | Computational | no | no |
| AXIN1_HUMAN | [view interactions] | Computational | no | yes |
| RAPSN_HUMAN | [view entry] [view interactions] | Computational | yes | no |