MACF1_HUMAN
Evidence for PS localization
Functions
F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules (PubMed, PubMed). Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex (PubMed). Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane . Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics . Interaction with CAMSAP3 at the minus ends of non-centrosomal microtubules tethers microtubules minus-ends to actin filaments, regulating focal adhesion size and cell migration (PubMed). May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4 (PubMed). Plays a key role in wound healing and epidermal cell migration . Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate microtubule dynamics and polarize hair follicle stem cells . As a regulator of actin and microtubule arrangement and stabilization, it plays an essential role in neurite outgrowth, branching and spine formation during brain development . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 7135 | Cys | Phe | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7186 | Asp | Tyr | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7188 | Cys | Phe | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
| 7188 | Cys | Gly | Lissencephaly9withcomplexbrainstemmalformation(LIS9) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MACF1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 28.5714 | 4 | no |
| GO:0003723 | RNA binding | 27.2727 | 4 | yes |
| GO:0019900 | kinase binding | 27.2727 | 4 | no |
| GO:0019901 | protein kinase binding | 25.9740 | 5 | no |
| GO:0000166 | nucleotide binding | 23.3766 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.3766 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 23.3766 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.3766 | 4 | no |
| GO:0003779 | actin binding | 22.0779 | 4 | yes |
| GO:0043169 | cation binding | 20.7792 | 4 | yes |
| GO:0045296 | cadherin binding | 20.7792 | 4 | yes |
| GO:0046872 | metal ion binding | 20.7792 | 5 | yes |
| GO:0015631 | tubulin binding | 19.4805 | 4 | yes |
| GO:0008017 | microtubule binding | 15.5844 | 5 | yes |
| GO:0005509 | calcium ion binding | 6.4935 | 6 | yes |
| GO:0051011 | microtubule minus-end binding | 2.5974 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MACF1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 75.3247 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 66.2338 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 59.7403 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 55.8442 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 55.8442 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.5455 | 4 | no |
| GO:0008104 | protein localization | 49.3506 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.7532 | 4 | yes |
| GO:0022607 | cellular component assembly | 46.7532 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.4545 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 45.4545 | 5 | no |
| GO:0006996 | organelle organization | 44.1558 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 44.1558 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 44.1558 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 44.1558 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 42.8571 | 5 | no |
| GO:0010468 | regulation of gene expression | 41.5584 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 37.6623 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 37.6623 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 36.3636 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 36.3636 | 5 | no |
| GO:0051049 | regulation of transport | 36.3636 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 35.0649 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 33.7662 | 6 | yes |
| GO:0030030 | cell projection organization | 33.7662 | 4 | no |
| GO:0033043 | regulation of organelle organization | 33.7662 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 32.4675 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 31.1688 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.1688 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.5714 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 28.5714 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 28.5714 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 28.5714 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.5714 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 28.5714 | 6 | no |
| GO:0060341 | regulation of cellular localization | 28.5714 | 4 | no |
| GO:0007010 | cytoskeleton organization | 27.2727 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 27.2727 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 27.2727 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 27.2727 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 27.2727 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 25.9740 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.9740 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.9740 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.9740 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.9740 | 5 | no |
| GO:0051050 | positive regulation of transport | 25.9740 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 24.6753 | 4 | yes |
| GO:0032880 | regulation of protein localization | 24.6753 | 5 | no |
| GO:0043412 | macromolecule modification | 23.3766 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 23.3766 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 23.3766 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 23.3766 | 4 | no |
| GO:0034330 | cell junction organization | 23.3766 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 22.0779 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 22.0779 | 7 | yes |
| GO:0036211 | protein modification process | 22.0779 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.0779 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 22.0779 | 6 | no |
| GO:0009894 | regulation of catabolic process | 22.0779 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 22.0779 | 6 | no |
| GO:0030155 | regulation of cell adhesion | 20.7792 | 4 | yes |
| GO:0071702 | organic substance transport | 20.7792 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 20.7792 | 7 | no |
| GO:0031401 | positive regulation of protein modification process | 20.7792 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 20.7792 | 7 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.7792 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.7792 | 6 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 20.7792 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 19.4805 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 19.4805 | 4 | yes |
| GO:0072657 | protein localization to membrane | 19.4805 | 4 | yes |
| GO:0060284 | regulation of cell development | 18.1818 | 5 | yes |
| GO:2000145 | regulation of cell motility | 18.1818 | 4 | yes |
| GO:0001558 | regulation of cell growth | 16.8831 | 4 | yes |
| GO:0030334 | regulation of cell migration | 16.8831 | 5 | yes |
| GO:0031346 | positive regulation of cell projection organization | 16.8831 | 6 | yes |
| GO:0045597 | positive regulation of cell differentiation | 16.8831 | 5 | yes |
| GO:0048638 | regulation of developmental growth | 16.8831 | 4 | yes |
| GO:0051960 | regulation of nervous system development | 15.5844 | 5 | yes |
| GO:0032886 | regulation of microtubule-based process | 14.2857 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 14.2857 | 6 | yes |
| GO:1990778 | protein localization to cell periphery | 14.2857 | 5 | yes |
| GO:0015031 | protein transport | 12.9870 | 4 | yes |
| GO:0030516 | regulation of axon extension | 12.9870 | 5 | yes |
| GO:0061387 | regulation of extent of cell growth | 12.9870 | 5 | yes |
| GO:0072659 | protein localization to plasma membrane | 12.9870 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 12.9870 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 11.6883 | 6 | yes |
| GO:0022604 | regulation of cell morphogenesis | 11.6883 | 5 | yes |
| GO:0051962 | positive regulation of nervous system development | 11.6883 | 5 | yes |
| GO:0045927 | positive regulation of growth | 10.3896 | 4 | yes |
| GO:0050769 | positive regulation of neurogenesis | 10.3896 | 6 | yes |
| GO:0001952 | regulation of cell-matrix adhesion | 9.0909 | 6 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 9.0909 | 5 | yes |
| GO:0016055 | Wnt signaling pathway | 9.0909 | 4 | yes |
| GO:0030307 | positive regulation of cell growth | 9.0909 | 5 | yes |
| GO:0050770 | regulation of axonogenesis | 9.0909 | 5 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 7.7922 | 5 | yes |
| GO:0048639 | positive regulation of developmental growth | 7.7922 | 5 | yes |
| GO:0010632 | regulation of epithelial cell migration | 6.4935 | 4 | yes |
| GO:0045773 | positive regulation of axon extension | 6.4935 | 6 | yes |
| GO:0050772 | positive regulation of axonogenesis | 6.4935 | 6 | yes |
| GO:0051893 | regulation of focal adhesion assembly | 6.4935 | 7 | yes |
| GO:0090109 | regulation of cell-substrate junction assembly | 6.4935 | 6 | yes |
| GO:0150116 | regulation of cell-substrate junction organization | 6.4935 | 5 | yes |
| GO:0006892 | post-Golgi vesicle-mediated transport | 5.1948 | 4 | yes |
| GO:0030177 | positive regulation of Wnt signaling pathway | 5.1948 | 6 | yes |
| GO:0090150 | establishment of protein localization to membrane | 5.1948 | 4 | yes |
| GO:0006893 | Golgi to plasma membrane transport | 3.8961 | 4 | yes |
| GO:0061951 | establishment of protein localization to plasma membrane | 3.8961 | 5 | yes |
| GO:0150011 | regulation of neuron projection arborization | 3.8961 | 6 | yes |
| GO:0042060 | wound healing | 2.5974 | 4 | yes |
| GO:0043001 | Golgi to plasma membrane protein transport | 2.5974 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UBP14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MACF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MARE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CLAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISCA1_HUMAN | [view interactions] | High throughput | no | yes |
| C2C4B_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| RSMB_HUMAN | [view interactions] | High throughput | no | yes |
| RU1C_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD5_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| LRBA_HUMAN | [view interactions] | High throughput | no | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX3_HUMAN | [view interactions] | High throughput | no | yes |
| 2A5E_HUMAN | [view interactions] | High throughput | no | yes |
| PRP16_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKIL_HUMAN | [view interactions] | High throughput | no | yes |
| MCAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ID2_HUMAN | [view interactions] | High throughput | no | no |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| ALX3_HUMAN | [view interactions] | High throughput | no | no |
| AMERL_HUMAN | [view interactions] | High throughput | no | no |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H33_HUMAN | [view interactions] | High throughput | no | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MK09_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| CHP3_HUMAN | [view interactions] | High throughput | no | yes |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| NRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| LCOR_HUMAN | [view interactions] | High throughput | no | yes |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| PCNT_HUMAN | [view interactions] | High throughput | no | yes |
| PKNX1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERR1_HUMAN | [view interactions] | High throughput | no | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| NRCAM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NRX1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLXD1_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRX2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TNG6_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP4_HUMAN | [view interactions] | High throughput | no | no |
| ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEN1_HUMAN | [view interactions] | High throughput | no | no |
| FHL1_HUMAN | [view interactions] | High throughput | no | no |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| TTC29_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAXX_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTBD8_HUMAN | [view interactions] | High throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT2_HUMAN | [view interactions] | High throughput | no | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| WIPI2_HUMAN | [view interactions] | High throughput | no | yes |
| BATF3_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |