LIS1_HUMAN
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates to the PAF inactivation. Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner . Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors . Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Required for dynein recruitment to microtubule plus ends and BICD2-bound cargos (PubMed). May modulate the Reelin pathway through interaction of the PAF-AH (I) catalytic dimer with VLDLR . [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in LIS1_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 32.5000 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 32.5000 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 30.0000 | 4 | no |
GO:0019900 | kinase binding | 27.5000 | 4 | no |
GO:0019901 | protein kinase binding | 25.0000 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 25.0000 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | no |
GO:0005524 | ATP binding | 22.5000 | 5 | no |
GO:0045296 | cadherin binding | 21.2500 | 4 | no |
GO:0015631 | tubulin binding | 20.0000 | 4 | yes |
GO:0008017 | microtubule binding | 18.7500 | 5 | yes |
GO:0051010 | microtubule plus-end binding | 12.5000 | 6 | yes |
GO:0046982 | protein heterodimerization activity | 8.7500 | 4 | yes |
GO:0034452 | dynactin binding | 2.5000 | 4 | yes |
GO:0043274 | phospholipase binding | 2.5000 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in LIS1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 55.0000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 52.5000 | 4 | yes |
GO:0006996 | organelle organization | 51.2500 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 46.2500 | 4 | yes |
GO:0022607 | cellular component assembly | 43.7500 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 38.7500 | 4 | no |
GO:0007010 | cytoskeleton organization | 38.7500 | 5 | yes |
GO:0010646 | regulation of cell communication | 38.7500 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 37.5000 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 37.5000 | 4 | no |
GO:0008104 | protein localization | 37.5000 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 36.2500 | 4 | no |
GO:0009966 | regulation of signal transduction | 35.0000 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 33.7500 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 33.7500 | 4 | no |
GO:0033043 | regulation of organelle organization | 33.7500 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 31.2500 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 31.2500 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 31.2500 | 5 | no |
GO:0051130 | positive regulation of cellular component organization | 28.7500 | 5 | yes |
GO:0051493 | regulation of cytoskeleton organization | 28.7500 | 6 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.7500 | 5 | no |
GO:0051049 | regulation of transport | 27.5000 | 4 | no |
GO:0031399 | regulation of protein modification process | 26.2500 | 6 | no |
GO:0030030 | cell projection organization | 26.2500 | 4 | yes |
GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 25.0000 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 25.0000 | 5 | yes |
GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | yes |
GO:0023056 | positive regulation of signaling | 25.0000 | 4 | yes |
GO:0051726 | regulation of cell cycle | 23.7500 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 23.7500 | 5 | yes |
GO:0010468 | regulation of gene expression | 23.7500 | 5 | no |
GO:0043254 | regulation of protein-containing complex assembly | 23.7500 | 5 | no |
GO:0071310 | cellular response to organic substance | 23.7500 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 22.5000 | 5 | yes |
GO:0071702 | organic substance transport | 21.2500 | 4 | yes |
GO:0071705 | nitrogen compound transport | 21.2500 | 4 | yes |
GO:0097435 | supramolecular fiber organization | 21.2500 | 4 | yes |
GO:0042325 | regulation of phosphorylation | 21.2500 | 7 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 21.2500 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 21.2500 | 6 | no |
GO:0009892 | negative regulation of metabolic process | 21.2500 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 21.2500 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.2500 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 21.2500 | 4 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.0000 | 6 | yes |
GO:0031344 | regulation of cell projection organization | 20.0000 | 5 | yes |
GO:0032886 | regulation of microtubule-based process | 20.0000 | 4 | yes |
GO:0070507 | regulation of microtubule cytoskeleton organization | 18.7500 | 5 | yes |
GO:0080134 | regulation of response to stress | 18.7500 | 4 | yes |
GO:0015031 | protein transport | 18.7500 | 4 | yes |
GO:0070925 | organelle assembly | 17.5000 | 5 | yes |
GO:0048585 | negative regulation of response to stimulus | 16.2500 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 16.2500 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 16.2500 | 4 | yes |
GO:0048812 | neuron projection morphogenesis | 15.0000 | 7 | yes |
GO:0048858 | cell projection morphogenesis | 15.0000 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 15.0000 | 4 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 15.0000 | 6 | yes |
GO:0001558 | regulation of cell growth | 15.0000 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 15.0000 | 5 | yes |
GO:0010975 | regulation of neuron projection development | 15.0000 | 7 | yes |
GO:0023057 | negative regulation of signaling | 15.0000 | 4 | yes |
GO:0032990 | cell part morphogenesis | 15.0000 | 4 | yes |
GO:0050807 | regulation of synapse organization | 13.7500 | 5 | yes |
GO:0061024 | membrane organization | 13.7500 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 13.7500 | 5 | yes |
GO:0030705 | cytoskeleton-dependent intracellular transport | 13.7500 | 4 | yes |
GO:0051336 | regulation of hydrolase activity | 12.5000 | 4 | yes |
GO:1902850 | microtubule cytoskeleton organization involved in mitosis | 12.5000 | 4 | yes |
GO:0022411 | cellular component disassembly | 12.5000 | 4 | yes |
GO:0051960 | regulation of nervous system development | 11.2500 | 5 | yes |
GO:0060284 | regulation of cell development | 11.2500 | 5 | yes |
GO:0099111 | microtubule-based transport | 11.2500 | 4 | yes |
GO:0001764 | neuron migration | 11.2500 | 4 | yes |
GO:0010970 | transport along microtubule | 11.2500 | 4 | yes |
GO:0030307 | positive regulation of cell growth | 11.2500 | 5 | yes |
GO:0031346 | positive regulation of cell projection organization | 11.2500 | 6 | yes |
GO:0043408 | regulation of MAPK cascade | 11.2500 | 6 | yes |
GO:0045597 | positive regulation of cell differentiation | 11.2500 | 5 | yes |
GO:0045927 | positive regulation of growth | 11.2500 | 4 | yes |
GO:0051650 | establishment of vesicle localization | 10.0000 | 4 | yes |
GO:0080135 | regulation of cellular response to stress | 10.0000 | 4 | yes |
GO:0007346 | regulation of mitotic cell cycle | 10.0000 | 5 | yes |
GO:0007409 | axonogenesis | 10.0000 | 8 | yes |
GO:0045787 | positive regulation of cell cycle | 10.0000 | 5 | yes |
GO:0048638 | regulation of developmental growth | 8.7500 | 4 | yes |
GO:0050767 | regulation of neurogenesis | 8.7500 | 6 | yes |
GO:0050770 | regulation of axonogenesis | 8.7500 | 5 | yes |
GO:0051293 | establishment of spindle localization | 8.7500 | 4 | yes |
GO:0061387 | regulation of extent of cell growth | 8.7500 | 5 | yes |
GO:0072384 | organelle transport along microtubule | 8.7500 | 4 | yes |
GO:0010720 | positive regulation of cell development | 8.7500 | 6 | yes |
GO:0022604 | regulation of cell morphogenesis | 8.7500 | 5 | yes |
GO:0030516 | regulation of axon extension | 8.7500 | 5 | yes |
GO:0031122 | cytoplasmic microtubule organization | 8.7500 | 4 | yes |
GO:0031345 | negative regulation of cell projection organization | 8.7500 | 6 | yes |
GO:0051962 | positive regulation of nervous system development | 7.5000 | 5 | yes |
GO:0099518 | vesicle cytoskeletal trafficking | 7.5000 | 5 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 7.5000 | 6 | yes |
GO:0040001 | establishment of mitotic spindle localization | 7.5000 | 5 | yes |
GO:0043087 | regulation of GTPase activity | 7.5000 | 5 | yes |
GO:0047496 | vesicle transport along microtubule | 6.2500 | 5 | yes |
GO:0048639 | positive regulation of developmental growth | 6.2500 | 5 | yes |
GO:0050769 | positive regulation of neurogenesis | 6.2500 | 6 | yes |
GO:0050772 | positive regulation of axonogenesis | 6.2500 | 6 | yes |
GO:0050773 | regulation of dendrite development | 6.2500 | 4 | yes |
GO:0050890 | cognition | 6.2500 | 4 | yes |
GO:0051294 | establishment of spindle orientation | 6.2500 | 5 | yes |
GO:0071763 | nuclear membrane organization | 6.2500 | 5 | yes |
GO:0001667 | ameboidal-type cell migration | 6.2500 | 4 | yes |
GO:0007097 | nuclear migration | 6.2500 | 4 | yes |
GO:0008088 | axo-dendritic transport | 6.2500 | 5 | yes |
GO:0010976 | positive regulation of neuron projection development | 6.2500 | 7 | yes |
GO:0010977 | negative regulation of neuron projection development | 6.2500 | 7 | yes |
GO:0021955 | central nervous system neuron axonogenesis | 6.2500 | 9 | yes |
GO:0030182 | neuron differentiation | 6.2500 | 4 | yes |
GO:0030865 | cortical cytoskeleton organization | 6.2500 | 6 | yes |
GO:0045773 | positive regulation of axon extension | 6.2500 | 6 | yes |
GO:0048666 | neuron development | 5.0000 | 4 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 5.0000 | 5 | yes |
GO:0051081 | nuclear membrane disassembly | 5.0000 | 6 | yes |
GO:0060998 | regulation of dendritic spine development | 5.0000 | 4 | yes |
GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 5.0000 | 5 | yes |
GO:0098930 | axonal transport | 5.0000 | 6 | yes |
GO:0099175 | regulation of postsynapse organization | 5.0000 | 6 | yes |
GO:0000132 | establishment of mitotic spindle orientation | 5.0000 | 6 | yes |
GO:0008090 | retrograde axonal transport | 5.0000 | 7 | yes |
GO:0010769 | regulation of cell morphogenesis involved in differentiation | 5.0000 | 6 | yes |
GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 5.0000 | 7 | yes |
GO:0016050 | vesicle organization | 5.0000 | 5 | yes |
GO:0030397 | membrane disassembly | 5.0000 | 5 | yes |
GO:0032872 | regulation of stress-activated MAPK cascade | 5.0000 | 6 | yes |
GO:0045995 | regulation of embryonic development | 5.0000 | 5 | yes |
GO:0046328 | regulation of JNK cascade | 5.0000 | 7 | yes |
GO:0046903 | secretion | 3.7500 | 4 | yes |
GO:0050905 | neuromuscular process | 3.7500 | 4 | yes |
GO:0060759 | regulation of response to cytokine stimulus | 3.7500 | 4 | yes |
GO:0060999 | positive regulation of dendritic spine development | 3.7500 | 5 | yes |
GO:0061001 | regulation of dendritic spine morphogenesis | 3.7500 | 5 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 3.7500 | 5 | yes |
GO:0099537 | trans-synaptic signaling | 3.7500 | 4 | yes |
GO:0001959 | regulation of cytokine-mediated signaling pathway | 3.7500 | 5 | yes |
GO:0007268 | chemical synaptic transmission | 3.7500 | 6 | yes |
GO:0016042 | lipid catabolic process | 3.7500 | 4 | yes |
GO:0043409 | negative regulation of MAPK cascade | 3.7500 | 7 | yes |
GO:0048854 | brain morphogenesis | 2.5000 | 4 | yes |
GO:0050775 | positive regulation of dendrite morphogenesis | 2.5000 | 6 | yes |
GO:0050885 | neuromuscular process controlling balance | 2.5000 | 5 | yes |
GO:0051012 | microtubule sliding | 2.5000 | 4 | yes |
GO:0051660 | establishment of centrosome localization | 2.5000 | 4 | yes |
GO:0051661 | maintenance of centrosome location | 2.5000 | 4 | yes |
GO:0060117 | auditory receptor cell development | 2.5000 | 6 | yes |
GO:0060119 | inner ear receptor cell development | 2.5000 | 5 | yes |
GO:0060760 | positive regulation of response to cytokine stimulus | 2.5000 | 5 | yes |
GO:0061003 | positive regulation of dendritic spine morphogenesis | 2.5000 | 6 | yes |
GO:0061515 | myeloid cell development | 2.5000 | 4 | yes |
GO:0070303 | negative regulation of stress-activated protein kinase signaling cascade | 2.5000 | 6 | yes |
GO:0071692 | protein localization to extracellular region | 2.5000 | 5 | yes |
GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity | 2.5000 | 4 | yes |
GO:0098751 | bone cell development | 2.5000 | 4 | yes |
GO:0001736 | establishment of planar polarity | 2.5000 | 4 | yes |
GO:0001961 | positive regulation of cytokine-mediated signaling pathway | 2.5000 | 6 | yes |
GO:0006644 | phospholipid metabolic process | 2.5000 | 4 | yes |
GO:0006650 | glycerophospholipid metabolic process | 2.5000 | 5 | yes |
GO:0006662 | glycerol ether metabolic process | 2.5000 | 4 | yes |
GO:0007405 | neuroblast proliferation | 2.5000 | 4 | yes |
GO:0008344 | adult locomotory behavior | 2.5000 | 4 | yes |
GO:0009306 | protein secretion | 2.5000 | 4 | yes |
GO:0021540 | corpus callosum morphogenesis | 2.5000 | 11 | yes |
GO:0021895 | cerebral cortex neuron differentiation | 2.5000 | 6 | yes |
GO:0021952 | central nervous system projection neuron axonogenesis | 2.5000 | 10 | yes |
GO:0021953 | central nervous system neuron differentiation | 2.5000 | 5 | yes |
GO:0032873 | negative regulation of stress-activated MAPK cascade | 2.5000 | 7 | yes |
GO:0033363 | secretory granule organization | 2.5000 | 6 | yes |
GO:0035592 | establishment of protein localization to extracellular region | 2.5000 | 4 | yes |
GO:0036035 | osteoclast development | 2.5000 | 5 | yes |
GO:0038026 | reelin-mediated signaling pathway | 2.5000 | 4 | yes |
GO:0040019 | positive regulation of embryonic development | 2.5000 | 5 | yes |
GO:0042249 | establishment of planar polarity of embryonic epithelium | 2.5000 | 5 | yes |
GO:0043622 | cortical microtubule organization | 2.5000 | 5 | yes |
GO:0045931 | positive regulation of mitotic cell cycle | 2.5000 | 6 | yes |
GO:0046329 | negative regulation of JNK cascade | 2.5000 | 8 | yes |
GO:0046469 | platelet activating factor metabolic process | 2.5000 | 4 | yes |
GO:0046485 | ether lipid metabolic process | 2.5000 | 4 | yes |
GO:0046486 | glycerolipid metabolic process | 2.5000 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NDEL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PA1B3_HUMAN | [view interactions] | Low throughput | no | no |
NUDC_HUMAN | [view interactions] | Low throughput | no | yes |
NDE1_HUMAN | [view interactions] | Low throughput | no | yes |
CENPF_HUMAN | [view interactions] | Low throughput | no | no |
PA1B2_HUMAN | [view interactions] | Low throughput | no | yes |
DYHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NUDC3_HUMAN | [view interactions] | Low throughput | no | yes |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NUDC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LIS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DCTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DCTN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KTNB1_HUMAN | [view interactions] | Low throughput | no | yes |
DCX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DYL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MAP1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DC1I1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KTNA1_HUMAN | [view interactions] | Low throughput | no | yes |
PDE4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDE4D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RHG01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RELN_HUMAN | [view interactions] | Low throughput | no | no |
DAB1_HUMAN | [view interactions] | Low throughput | no | yes |
TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GLUT4_HUMAN | [view interactions] | High throughput | no | no |
IQCB1_HUMAN | [view interactions] | High throughput | no | no |
CCSE2_HUMAN | [view interactions] | High throughput | no | yes |
DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CP135_HUMAN | [view interactions] | High throughput | no | no |
CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA5_HUMAN | [view interactions] | High throughput | no | yes |
GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IMPCT_HUMAN | [view interactions] | High throughput | no | yes |
IPO4_HUMAN | [view interactions] | High throughput | no | no |
DIXC1_HUMAN | [view interactions] | High throughput | no | no |
ZN616_HUMAN | [view interactions] | High throughput | no | yes |
H6ST2_HUMAN | [view interactions] | High throughput | no | no |
DLRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KI20B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGLN_HUMAN | [view interactions] | High throughput | no | no |
SYK_HUMAN | [view interactions] | High throughput | no | yes |
FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EDIL3_HUMAN | [view interactions] | High throughput | no | yes |
TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLST_HUMAN | [view interactions] | High throughput | no | yes |
CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
PPR18_HUMAN | [view interactions] | High throughput | no | no |
DYLT1_HUMAN | [view interactions] | High throughput | no | no |
DLRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GID8_HUMAN | [view interactions] | High throughput | no | yes |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYLT3_HUMAN | [view interactions] | High throughput | no | yes |
CIAO1_HUMAN | [view interactions] | High throughput | no | yes |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CE128_HUMAN | [view interactions] | High throughput | no | yes |
BET1_HUMAN | [view interactions] | High throughput | no | no |
UFO_HUMAN | [view interactions] | High throughput | no | no |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
VGFR1_HUMAN | [view interactions] | High throughput | no | no |
FLT3_HUMAN | [view interactions] | High throughput | no | no |
LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
MARE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AHI1_HUMAN | [view interactions] | High throughput | no | yes |
DYT2B_HUMAN | [view interactions] | High throughput | no | no |
TANK_HUMAN | [view interactions] | High throughput | no | yes |
WDR5_HUMAN | [view interactions] | High throughput | no | no |
CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ISG15_HUMAN | [view interactions] | High throughput | no | no |
CDK2_HUMAN | [view interactions] | High throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
ATX3_HUMAN | [view interactions] | High throughput | no | yes |
TEST_HUMAN | [view interactions] | High throughput | no | no |
NELFD_HUMAN | [view interactions] | High throughput | no | yes |
ARI4B_HUMAN | [view interactions] | High throughput | no | yes |
LNX1_HUMAN | [view interactions] | High throughput | no | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
RNF4_HUMAN | [view interactions] | High throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
NINL_HUMAN | [view interactions] | High throughput | no | yes |
CDK1_HUMAN | [view interactions] | High throughput | no | no |
THIM_HUMAN | [view interactions] | High throughput | no | yes |
CIA2B_HUMAN | [view interactions] | High throughput | no | yes |
CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CUL4A_HUMAN | [view interactions] | High throughput | no | no |
CCND1_HUMAN | [view interactions] | High throughput | no | yes |
SOSD1_HUMAN | [view interactions] | High throughput | no | no |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARP10_HUMAN | [view interactions] | High throughput | no | no |
APC13_HUMAN | [view interactions] | High throughput | no | no |
ARL2_HUMAN | [view interactions] | High throughput | no | yes |
CENPK_HUMAN | [view interactions] | High throughput | no | no |
CENPM_HUMAN | [view interactions] | High throughput | no | yes |
CE152_HUMAN | [view interactions] | High throughput | no | yes |
FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNL3L_HUMAN | [view interactions] | High throughput | no | yes |
BACD3_HUMAN | [view interactions] | High throughput | no | yes |
CE295_HUMAN | [view interactions] | High throughput | no | yes |
KIF11_HUMAN | [view interactions] | High throughput | no | yes |
MPH6_HUMAN | [view interactions] | High throughput | no | yes |
MZT1_HUMAN | [view interactions] | High throughput | no | yes |
2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PSD12_HUMAN | [view interactions] | High throughput | no | yes |
RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL36A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
C560_HUMAN | [view interactions] | High throughput | no | no |
SGO1_HUMAN | [view interactions] | High throughput | no | no |
SKA3_HUMAN | [view interactions] | High throughput | no | no |
RUXG_HUMAN | [view interactions] | High throughput | no | yes |
TCOF_HUMAN | [view interactions] | High throughput | no | yes |
SAE2_HUMAN | [view interactions] | High throughput | no | yes |
VPS72_HUMAN | [view interactions] | High throughput | no | no |
ZN574_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RIT1_HUMAN | [view interactions] | High throughput | no | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
ASNS_HUMAN | [view interactions] | High throughput | no | yes |
HMGB3_HUMAN | [view interactions] | High throughput | no | no |
PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAN2_HUMAN | [view interactions] | High throughput | no | no |
CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
IF5_HUMAN | [view interactions] | High throughput | no | yes |
ISOC1_HUMAN | [view interactions] | High throughput | no | no |
MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYO1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
SMD2_HUMAN | [view interactions] | High throughput | no | yes |
TATD1_HUMAN | [view interactions] | High throughput | no | yes |
UBXN1_HUMAN | [view interactions] | High throughput | no | no |
PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RUXF_HUMAN | [view interactions] | High throughput | no | no |
AP1G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CHID1_HUMAN | [view interactions] | High throughput | no | yes |
CHM2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSTF1_HUMAN | [view interactions] | High throughput | no | yes |
SBDS_HUMAN | [view interactions] | High throughput | no | yes |
SCLY_HUMAN | [view interactions] | High throughput | no | yes |
CENPE_HUMAN | [view interactions] | High throughput | no | no |
DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPR_HUMAN | [view interactions] | High throughput | no | yes |
ZWINT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KIF3B_HUMAN | [view interactions] | High throughput | no | no |
NUP85_HUMAN | [view interactions] | High throughput | no | yes |
ZN276_HUMAN | [view interactions] | High throughput | no | yes |
NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
MK11_HUMAN | [view interactions] | High throughput | no | yes |
ANR28_HUMAN | [view interactions] | High throughput | no | no |
AP4E1_HUMAN | [view interactions] | High throughput | no | no |
CPSF3_HUMAN | [view interactions] | High throughput | no | yes |
DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRS8_HUMAN | [view interactions] | High throughput | no | yes |
DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KIF1B_HUMAN | [view interactions] | High throughput | no | yes |
PCNT_HUMAN | [view interactions] | High throughput | no | yes |
PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
ENTR1_HUMAN | [view interactions] | High throughput | no | no |
TSR1_HUMAN | [view interactions] | High throughput | no | no |
FURIN_HUMAN | [view interactions] | High throughput | no | yes |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LPCT4_HUMAN | [view interactions] | Computational | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DYH1_HUMAN | [view interactions] | Computational | no | yes |
NDC80_HUMAN | [view interactions] | Computational | no | no |
DCTN6_HUMAN | [view interactions] | Computational | no | no |
CDK5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DYH5_HUMAN | [view interactions] | Computational | no | no |
MARE3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
BUB1_HUMAN | [view interactions] | Computational | no | no |
PCAT1_HUMAN | [view interactions] | Computational | no | yes |
PCAT2_HUMAN | [view interactions] | Computational | no | yes |
PAFA_HUMAN | [view interactions] | Computational | no | no |
ZW10_HUMAN | [view interactions] | Computational | no | yes |
BUB3_HUMAN | [view interactions] | Computational | no | yes |
ACTZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DYH6_HUMAN | [view interactions] | Computational | no | no |
DYH3_HUMAN | [view interactions] | Computational | no | no |
VLDLR_HUMAN | [view interactions] | Computational | no | yes |
PAFA2_HUMAN | [view interactions] | Computational | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLK1_HUMAN | [view interactions] | Computational | no | yes |