DLG5_HUMAN
Evidence for PS localization
Functions
Acts as a regulator of the Hippo signaling pathway (PubMed, PubMed). Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1 (PubMed). Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transition (EMT), cell migration and invasion (PubMed). Plays an important role in dendritic spine formation and synaptogenesis in cortical neurons; regulates synaptogenesis by enhancing the cell surface localization of N-cadherin. Acts as a positive regulator of hedgehog (Hh) signaling pathway. Plays a critical role in the early point of the SMO activity cycle by interacting with SMO at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DLG5_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 35.9375 | 4 | no |
| GO:0019901 | protein kinase binding | 35.9375 | 5 | no |
| GO:0017076 | purine nucleotide binding | 29.6875 | 4 | no |
| GO:0045296 | cadherin binding | 28.1250 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 26.5625 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.5625 | 4 | no |
| GO:0030159 | signaling receptor complex adaptor activity | 3.1250 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DLG5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 70.3125 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 67.1875 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 64.0625 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 60.9375 | 4 | no |
| GO:0006996 | organelle organization | 56.2500 | 4 | no |
| GO:0008104 | protein localization | 54.6875 | 4 | yes |
| GO:0022607 | cellular component assembly | 53.1250 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 53.1250 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.1250 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 53.1250 | 4 | no |
| GO:0010646 | regulation of cell communication | 50.0000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 48.4375 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 46.8750 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 46.8750 | 5 | no |
| GO:0009966 | regulation of signal transduction | 45.3125 | 4 | yes |
| GO:0030030 | cell projection organization | 42.1875 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 40.6250 | 4 | yes |
| GO:0007010 | cytoskeleton organization | 40.6250 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 39.0625 | 5 | no |
| GO:0033043 | regulation of organelle organization | 39.0625 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | no |
| GO:0051049 | regulation of transport | 37.5000 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 35.9375 | 5 | yes |
| GO:0071702 | organic substance transport | 35.9375 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.3750 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 34.3750 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.8125 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 32.8125 | 5 | no |
| GO:0010941 | regulation of cell death | 32.8125 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 32.8125 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 32.8125 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 31.2500 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 31.2500 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 31.2500 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 31.2500 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 31.2500 | 6 | no |
| GO:0009889 | regulation of biosynthetic process | 31.2500 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 31.2500 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.6875 | 6 | no |
| GO:0030155 | regulation of cell adhesion | 29.6875 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 29.6875 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 29.6875 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 29.6875 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 29.6875 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.6875 | 4 | no |
| GO:0071310 | cellular response to organic substance | 29.6875 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.1250 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 28.1250 | 6 | no |
| GO:0015031 | protein transport | 28.1250 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 28.1250 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.1250 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.1250 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 26.5625 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.5625 | 6 | no |
| GO:0097435 | supramolecular fiber organization | 26.5625 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 26.5625 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 26.5625 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 26.5625 | 4 | yes |
| GO:2000145 | regulation of cell motility | 26.5625 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.5625 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 26.5625 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.5625 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.5625 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 26.5625 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 26.5625 | 5 | no |
| GO:0030334 | regulation of cell migration | 25.0000 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 25.0000 | 4 | yes |
| GO:0010628 | positive regulation of gene expression | 25.0000 | 6 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 25.0000 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 23.4375 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.4375 | 5 | yes |
| GO:0034330 | cell junction organization | 23.4375 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 23.4375 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 23.4375 | 5 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 21.8750 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.8750 | 5 | no |
| GO:0036211 | protein modification process | 21.8750 | 4 | no |
| GO:0043412 | macromolecule modification | 21.8750 | 4 | no |
| GO:0045785 | positive regulation of cell adhesion | 21.8750 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.8750 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.8750 | 7 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 21.8750 | 5 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 20.3125 | 5 | no |
| GO:0022604 | regulation of cell morphogenesis | 20.3125 | 5 | no |
| GO:0051726 | regulation of cell cycle | 20.3125 | 4 | no |
| GO:0007015 | actin filament organization | 20.3125 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 20.3125 | 7 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 20.3125 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.3125 | 6 | yes |
| GO:0060548 | negative regulation of cell death | 20.3125 | 5 | no |
| GO:0061024 | membrane organization | 20.3125 | 4 | no |
| GO:0006886 | intracellular protein transport | 20.3125 | 4 | no |
| GO:0022407 | regulation of cell-cell adhesion | 17.1875 | 5 | yes |
| GO:0034329 | cell junction assembly | 17.1875 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 15.6250 | 4 | yes |
| GO:0045216 | cell-cell junction organization | 15.6250 | 5 | yes |
| GO:0051960 | regulation of nervous system development | 15.6250 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 15.6250 | 5 | yes |
| GO:0002009 | morphogenesis of an epithelium | 14.0625 | 4 | yes |
| GO:0040013 | negative regulation of locomotion | 14.0625 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 14.0625 | 5 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 14.0625 | 6 | yes |
| GO:0002694 | regulation of leukocyte activation | 12.5000 | 4 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 12.5000 | 5 | yes |
| GO:0050807 | regulation of synapse organization | 12.5000 | 5 | yes |
| GO:0050865 | regulation of cell activation | 12.5000 | 4 | yes |
| GO:2000146 | negative regulation of cell motility | 12.5000 | 5 | yes |
| GO:0007043 | cell-cell junction assembly | 10.9375 | 6 | yes |
| GO:0030336 | negative regulation of cell migration | 10.9375 | 6 | yes |
| GO:0050863 | regulation of T cell activation | 10.9375 | 6 | yes |
| GO:0051249 | regulation of lymphocyte activation | 10.9375 | 5 | yes |
| GO:0051962 | positive regulation of nervous system development | 10.9375 | 5 | yes |
| GO:0007162 | negative regulation of cell adhesion | 9.3750 | 5 | yes |
| GO:0035088 | establishment or maintenance of apical/basal cell polarity | 9.3750 | 4 | yes |
| GO:1901890 | positive regulation of cell junction assembly | 9.3750 | 6 | yes |
| GO:1902414 | protein localization to cell junction | 9.3750 | 5 | yes |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 9.3750 | 6 | yes |
| GO:0002683 | negative regulation of immune system process | 7.8125 | 4 | yes |
| GO:0030855 | epithelial cell differentiation | 7.8125 | 4 | yes |
| GO:0034332 | adherens junction organization | 7.8125 | 6 | yes |
| GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 7.8125 | 5 | yes |
| GO:0150105 | protein localization to cell-cell junction | 7.8125 | 6 | yes |
| GO:0022408 | negative regulation of cell-cell adhesion | 6.2500 | 6 | yes |
| GO:0030859 | polarized epithelial cell differentiation | 6.2500 | 5 | yes |
| GO:0032944 | regulation of mononuclear cell proliferation | 6.2500 | 6 | yes |
| GO:0048754 | branching morphogenesis of an epithelial tube | 6.2500 | 4 | yes |
| GO:0050670 | regulation of lymphocyte proliferation | 6.2500 | 6 | yes |
| GO:0051963 | regulation of synapse assembly | 6.2500 | 6 | yes |
| GO:0070663 | regulation of leukocyte proliferation | 6.2500 | 5 | yes |
| GO:0001837 | epithelial to mesenchymal transition | 4.6875 | 5 | yes |
| GO:0002695 | negative regulation of leukocyte activation | 4.6875 | 5 | yes |
| GO:0032945 | negative regulation of mononuclear cell proliferation | 4.6875 | 7 | yes |
| GO:0042129 | regulation of T cell proliferation | 4.6875 | 7 | yes |
| GO:0048762 | mesenchymal cell differentiation | 4.6875 | 4 | yes |
| GO:0050672 | negative regulation of lymphocyte proliferation | 4.6875 | 7 | yes |
| GO:0050866 | negative regulation of cell activation | 4.6875 | 5 | yes |
| GO:0051250 | negative regulation of lymphocyte activation | 4.6875 | 6 | yes |
| GO:0051965 | positive regulation of synapse assembly | 4.6875 | 6 | yes |
| GO:0060441 | epithelial tube branching involved in lung morphogenesis | 4.6875 | 5 | yes |
| GO:0070664 | negative regulation of leukocyte proliferation | 4.6875 | 6 | yes |
| GO:0071896 | protein localization to adherens junction | 4.6875 | 7 | yes |
| GO:0008589 | regulation of smoothened signaling pathway | 3.1250 | 5 | yes |
| GO:0034333 | adherens junction assembly | 3.1250 | 7 | yes |
| GO:0042130 | negative regulation of T cell proliferation | 3.1250 | 8 | yes |
| GO:0045176 | apical protein localization | 3.1250 | 5 | yes |
| GO:0045880 | positive regulation of smoothened signaling pathway | 3.1250 | 6 | yes |
| GO:0050868 | negative regulation of T cell activation | 3.1250 | 7 | yes |
| GO:0060998 | regulation of dendritic spine development | 3.1250 | 4 | yes |
| GO:0060999 | positive regulation of dendritic spine development | 3.1250 | 5 | yes |
| GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 3.1250 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DLG5_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 3.1250 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.1250 | 5 | no |
| DOID:114 | heart disease | 3.1250 | 3 | no |
| DOID:331 | central nervous system disease | 3.1250 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| SKP1_HUMAN | [view interactions] | Low throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| VINEX_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| BTBDA_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| RPGR1_HUMAN | [view interactions] | High throughput | no | no |
| CEP89_HUMAN | [view interactions] | High throughput | no | no |
| CE104_HUMAN | [view interactions] | High throughput | no | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NAA11_HUMAN | [view interactions] | High throughput | no | no |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MELT_HUMAN | [view interactions] | High throughput | no | yes |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT1_HUMAN | [view interactions] | High throughput | no | yes |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| TNR6A_HUMAN | [view interactions] | High throughput | no | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB5_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB7_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| AMOT_HUMAN | [view interactions] | High throughput | no | no |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| LATS1_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UTP4_HUMAN | [view interactions] | High throughput | no | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTF2I_HUMAN | [view interactions] | High throughput | no | yes |
| RL21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| SCRIB_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| L2GL2_HUMAN | [view interactions] | Computational | no | yes |
| L2GL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |