MOES_HUMAN
Evidence for PS localization
Functions
Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton (PubMed). Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement (PubMed). These rearrangements regulate many cellular processes, including cell shape determination, membrane transport, and signal transduction (PubMed, PubMed). The role of moesin is particularly important in immunity acting on both T and B-cells homeostasis and self-tolerance, regulating lymphocyte egress from lymphoid organs (PubMed, PubMed). Modulates phagolysosomal biogenesis in macrophages . Participates also in immunologic synapse formation (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MOES_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 34.1772 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 34.1772 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.6456 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 26.5823 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 26.5823 | 5 | no |
| GO:0005524 | ATP binding | 24.0506 | 5 | no |
| GO:0003723 | RNA binding | 21.5190 | 4 | yes |
| GO:0019900 | kinase binding | 20.2532 | 4 | yes |
| GO:0045296 | cadherin binding | 20.2532 | 4 | no |
| GO:0019901 | protein kinase binding | 18.9873 | 5 | yes |
| GO:0003779 | actin binding | 17.7215 | 4 | yes |
| GO:0003725 | double-stranded RNA binding | 3.7975 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MOES_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 59.4937 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 54.4304 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.6329 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.6329 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 49.3671 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 48.1013 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 48.1013 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 44.3038 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.5063 | 5 | yes |
| GO:0010646 | regulation of cell communication | 40.5063 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 39.2405 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 39.2405 | 4 | no |
| GO:0010468 | regulation of gene expression | 37.9747 | 5 | yes |
| GO:0006996 | organelle organization | 37.9747 | 4 | no |
| GO:0008104 | protein localization | 36.7089 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.4430 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 35.4430 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 34.1772 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.1772 | 5 | no |
| GO:0033043 | regulation of organelle organization | 32.9114 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 32.9114 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.3797 | 4 | yes |
| GO:0022607 | cellular component assembly | 30.3797 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 30.3797 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 29.1139 | 4 | yes |
| GO:0051049 | regulation of transport | 29.1139 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 29.1139 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 29.1139 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.1139 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.1139 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 27.8481 | 6 | yes |
| GO:0060341 | regulation of cellular localization | 27.8481 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.8481 | 5 | no |
| GO:0032880 | regulation of protein localization | 26.5823 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 26.5823 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.5823 | 6 | no |
| GO:0031399 | regulation of protein modification process | 26.5823 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.5823 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.3165 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.3165 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.3165 | 4 | no |
| GO:0010941 | regulation of cell death | 25.3165 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.3165 | 5 | no |
| GO:0080134 | regulation of response to stress | 25.3165 | 4 | no |
| GO:0071702 | organic substance transport | 25.3165 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 24.0506 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.0506 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.0506 | 4 | no |
| GO:0043412 | macromolecule modification | 24.0506 | 4 | no |
| GO:0030334 | regulation of cell migration | 22.7848 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 22.7848 | 4 | yes |
| GO:2000145 | regulation of cell motility | 22.7848 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 22.7848 | 7 | no |
| GO:0071705 | nitrogen compound transport | 22.7848 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 22.7848 | 6 | no |
| GO:0036211 | protein modification process | 22.7848 | 4 | no |
| GO:0009894 | regulation of catabolic process | 21.5190 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 21.5190 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 21.5190 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 21.5190 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.5190 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 21.5190 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 21.5190 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 21.5190 | 5 | no |
| GO:0030030 | cell projection organization | 21.5190 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 20.2532 | 6 | yes |
| GO:0030155 | regulation of cell adhesion | 20.2532 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 20.2532 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 20.2532 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.2532 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.2532 | 7 | no |
| GO:0010648 | negative regulation of cell communication | 20.2532 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.2532 | 4 | no |
| GO:0060548 | negative regulation of cell death | 20.2532 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 20.2532 | 5 | no |
| GO:0015031 | protein transport | 20.2532 | 4 | no |
| GO:0014070 | response to organic cyclic compound | 18.9873 | 4 | yes |
| GO:0051050 | positive regulation of transport | 18.9873 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 17.7215 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 16.4557 | 5 | yes |
| GO:0032386 | regulation of intracellular transport | 16.4557 | 5 | yes |
| GO:1903829 | positive regulation of protein localization | 16.4557 | 5 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 15.1899 | 5 | yes |
| GO:0022604 | regulation of cell morphogenesis | 13.9241 | 5 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 13.9241 | 5 | yes |
| GO:0032535 | regulation of cellular component size | 12.6582 | 4 | yes |
| GO:0033993 | response to lipid | 12.6582 | 4 | yes |
| GO:1902115 | regulation of organelle assembly | 12.6582 | 5 | yes |
| GO:0008360 | regulation of cell shape | 11.3924 | 6 | yes |
| GO:0032388 | positive regulation of intracellular transport | 11.3924 | 5 | yes |
| GO:0042176 | regulation of protein catabolic process | 10.1266 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 10.1266 | 4 | yes |
| GO:0071396 | cellular response to lipid | 10.1266 | 5 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 8.8608 | 6 | yes |
| GO:0002064 | epithelial cell development | 7.5949 | 4 | yes |
| GO:0008361 | regulation of cell size | 7.5949 | 5 | yes |
| GO:0030855 | epithelial cell differentiation | 7.5949 | 4 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 7.5949 | 6 | yes |
| GO:1902117 | positive regulation of organelle assembly | 7.5949 | 6 | yes |
| GO:1903649 | regulation of cytoplasmic transport | 7.5949 | 6 | yes |
| GO:2000641 | regulation of early endosome to late endosome transport | 7.5949 | 5 | yes |
| GO:0001885 | endothelial cell development | 6.3291 | 5 | yes |
| GO:0035088 | establishment or maintenance of apical/basal cell polarity | 6.3291 | 4 | yes |
| GO:0042110 | T cell activation | 6.3291 | 4 | yes |
| GO:0061028 | establishment of endothelial barrier | 6.3291 | 6 | yes |
| GO:1901654 | response to ketone | 6.3291 | 4 | yes |
| GO:1901655 | cellular response to ketone | 6.3291 | 5 | yes |
| GO:1902965 | regulation of protein localization to early endosome | 6.3291 | 7 | yes |
| GO:1902966 | positive regulation of protein localization to early endosome | 6.3291 | 7 | yes |
| GO:1903651 | positive regulation of cytoplasmic transport | 6.3291 | 6 | yes |
| GO:1905666 | regulation of protein localization to endosome | 6.3291 | 6 | yes |
| GO:1905668 | positive regulation of protein localization to endosome | 6.3291 | 6 | yes |
| GO:2000643 | positive regulation of early endosome to late endosome transport | 6.3291 | 6 | yes |
| GO:0002685 | regulation of leukocyte migration | 5.0633 | 4 | yes |
| GO:0007159 | leukocyte cell-cell adhesion | 5.0633 | 4 | yes |
| GO:0033574 | response to testosterone | 5.0633 | 5 | yes |
| GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 5.0633 | 5 | yes |
| GO:0071394 | cellular response to testosterone stimulus | 5.0633 | 6 | yes |
| GO:0071675 | regulation of mononuclear cell migration | 5.0633 | 5 | yes |
| GO:0071801 | regulation of podosome assembly | 5.0633 | 6 | yes |
| GO:0071803 | positive regulation of podosome assembly | 5.0633 | 7 | yes |
| GO:0030859 | polarized epithelial cell differentiation | 3.7975 | 5 | yes |
| GO:0035089 | establishment of apical/basal cell polarity | 3.7975 | 5 | yes |
| GO:0045198 | establishment of epithelial cell apical/basal polarity | 3.7975 | 5 | yes |
| GO:0061162 | establishment of monopolar cell polarity | 3.7975 | 4 | yes |
| GO:0072676 | lymphocyte migration | 3.7975 | 4 | yes |
| GO:0072678 | T cell migration | 3.7975 | 5 | yes |
| GO:0090162 | establishment of epithelial cell polarity | 3.7975 | 4 | yes |
| GO:2000401 | regulation of lymphocyte migration | 3.7975 | 6 | yes |
| GO:0001771 | immunological synapse formation | 2.5316 | 4 | yes |
| GO:0022612 | gland morphogenesis | 2.5316 | 4 | yes |
| GO:0032943 | mononuclear cell proliferation | 2.5316 | 4 | yes |
| GO:0042098 | T cell proliferation | 2.5316 | 5 | yes |
| GO:0046651 | lymphocyte proliferation | 2.5316 | 4 | yes |
| GO:0070486 | leukocyte aggregation | 2.5316 | 5 | yes |
| GO:0070489 | T cell aggregation | 2.5316 | 7 | yes |
| GO:0071593 | lymphocyte aggregation | 2.5316 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MOES_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 2.5316 | 3 | no |
| DOID:0050686 | organ system cancer | 2.5316 | 3 | no |
| DOID:193 | reproductive organ cancer | 2.5316 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DCC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD44_HUMAN | [view interactions] | Low throughput | no | yes |
| TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ICAM3_HUMAN | [view interactions] | Low throughput | no | no |
| NCF1_HUMAN | [view interactions] | Low throughput | no | no |
| NCF4_HUMAN | [view interactions] | Low throughput | no | no |
| LEUK_HUMAN | [view interactions] | Low throughput | no | no |
| SPTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MCP_HUMAN | [view interactions] | Low throughput | no | no |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| LYAM1_HUMAN | [view interactions] | Low throughput | no | no |
| ICAM2_HUMAN | [view interactions] | Low throughput | no | no |
| SELPL_HUMAN | [view interactions] | Low throughput | no | no |
| VPS11_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MOES_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CRUM1_HUMAN | [view interactions] | Low throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | Low throughput | no | no |
| NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
| PLEK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KSYK_HUMAN | [view interactions] | Low throughput | no | no |
| M4K4_HUMAN | [view interactions] | Low throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| MK10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| SYUG_HUMAN | [view interactions] | High throughput | no | yes |
| ELF3_HUMAN | [view interactions] | High throughput | no | no |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYPC2_HUMAN | [view interactions] | High throughput | no | no |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBTN2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| ELOC_HUMAN | [view interactions] | High throughput | no | no |
| DYSF_HUMAN | [view interactions] | High throughput | no | no |
| ZMYM4_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPARG_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG28_HUMAN | [view interactions] | High throughput | no | no |
| ARHGF_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD151_HUMAN | [view interactions] | High throughput | no | no |
| K319L_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| WASC4_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| MNS1_HUMAN | [view interactions] | High throughput | no | no |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBP_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI15_HUMAN | [view interactions] | High throughput | no | no |
| BID_HUMAN | [view interactions] | High throughput | no | no |
| TR10B_HUMAN | [view interactions] | High throughput | no | no |
| FADD_HUMAN | [view interactions] | High throughput | no | yes |
| TNFL6_HUMAN | [view interactions] | High throughput | no | yes |
| MK08_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASPA_HUMAN | [view interactions] | High throughput | no | yes |
| CASP8_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF3C4_HUMAN | [view interactions] | High throughput | no | no |
| SRCAP_HUMAN | [view interactions] | High throughput | no | yes |
| S10AG_HUMAN | [view interactions] | High throughput | no | no |
| ASNS_HUMAN | [view interactions] | High throughput | no | yes |
| CAN2_HUMAN | [view interactions] | High throughput | no | no |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| PSF3_HUMAN | [view interactions] | High throughput | no | yes |
| GSHB_HUMAN | [view interactions] | High throughput | no | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ULA1_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| PUR4_HUMAN | [view interactions] | High throughput | no | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| STK24_HUMAN | [view interactions] | High throughput | no | yes |
| TATD1_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PA1B2_HUMAN | [view interactions] | High throughput | no | yes |
| PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPP2_HUMAN | [view interactions] | High throughput | no | no |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| CALR_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF5AL_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FABP5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAXC_HUMAN | [view interactions] | High throughput | no | no |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INO1_HUMAN | [view interactions] | High throughput | no | no |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLSL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| GDIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IMPA2_HUMAN | [view interactions] | High throughput | no | no |
| MAOX_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| 6PGD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK2_HUMAN | [view interactions] | High throughput | no | no |
| PLSI_HUMAN | [view interactions] | High throughput | no | no |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| RCN1_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| F13A_HUMAN | [view interactions] | High throughput | no | no |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPP2B_HUMAN | [view interactions] | High throughput | no | no |
| SL9A1_HUMAN | [view interactions] | High throughput | no | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| SCNAA_HUMAN | [view interactions] | High throughput | no | no |
| CD11B_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| APC13_HUMAN | [view interactions] | High throughput | no | no |
| CATZ_HUMAN | [view interactions] | High throughput | no | yes |
| ZN624_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS7_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNS_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK6_HUMAN | [view interactions] | High throughput | no | yes |
| ACD10_HUMAN | [view interactions] | High throughput | no | no |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZF64B_HUMAN | [view interactions] | High throughput | no | no |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| MISP_HUMAN | [view interactions] | High throughput | no | no |
| TSN33_HUMAN | [view interactions] | High throughput | no | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| SOST_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SDC2_HUMAN | [view interactions] | Computational | no | yes |
| STAT4_HUMAN | [view interactions] | Computational | no | yes |
| ROCK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ROCK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | Computational | yes | yes |