Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SC31A_HUMAN

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules . [View more on UniProt]

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No data found.

ELM instance Name Type Start End Partner
ELMI004598 DEG_Kelch_KLHL12_1 DEG 957 962 -
ELMI002659 LIG_EF_ALG2_ABM_1 LIG 870 879 -
ELMI002660 LIG_EF_ALG2_ABM_2 LIG 839 843 -
ELMI004598 DEG_Kelch_KLHL12_1 DEG 957 962 -
ELMI002659 LIG_EF_ALG2_ABM_1 LIG 870 879 -
ELMI002660 LIG_EF_ALG2_ABM_2 LIG 839 843 -

Molecular function

Term Name % Distance from the top of the tree Annotated in SC31A_HUMAN
GO:0000166 nucleotide binding 37.6812 4 no
GO:0017076 purine nucleotide binding 37.6812 5 no
GO:0043168 anion binding 36.2319 4 no
GO:0032555 purine ribonucleotide binding 34.7826 4 no
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 no
GO:0030554 adenyl nucleotide binding 30.4348 6 no
GO:0003723 RNA binding 28.9855 4 no
GO:0032559 adenyl ribonucleotide binding 27.5362 5 no
GO:0043169 cation binding 27.5362 4 no
GO:0046872 metal ion binding 27.5362 5 no
GO:0005524 ATP binding 26.0870 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SC31A_HUMAN
GO:0060255 regulation of macromolecule metabolic process 55.0725 4 no
GO:0048522 positive regulation of cellular process 52.1739 4 no
GO:0080090 regulation of primary metabolic process 52.1739 4 no
GO:0031323 regulation of cellular metabolic process 50.7246 4 no
GO:0008104 protein localization 44.9275 4 yes
GO:0009889 regulation of biosynthetic process 44.9275 4 no
GO:0010646 regulation of cell communication 44.9275 4 no
GO:0051128 regulation of cellular component organization 44.9275 4 no
GO:0031326 regulation of cellular biosynthetic process 43.4783 5 no
GO:0009893 positive regulation of metabolic process 42.0290 4 no
GO:0009966 regulation of signal transduction 42.0290 4 no
GO:0010604 positive regulation of macromolecule metabolic process 42.0290 5 no
GO:0010556 regulation of macromolecule biosynthetic process 42.0290 5 no
GO:0051246 regulation of protein metabolic process 42.0290 5 no
GO:0048523 negative regulation of cellular process 40.5797 4 no
GO:0010468 regulation of gene expression 40.5797 6 no
GO:0071702 organic substance transport 37.6812 4 yes
GO:0009892 negative regulation of metabolic process 37.6812 4 no
GO:0043412 macromolecule modification 36.2319 4 no
GO:0023056 positive regulation of signaling 36.2319 4 no
GO:0010605 negative regulation of macromolecule metabolic process 36.2319 5 no
GO:0051247 positive regulation of protein metabolic process 36.2319 6 no
GO:0071705 nitrogen compound transport 34.7826 4 yes
GO:0036211 protein modification process 34.7826 4 no
GO:0010647 positive regulation of cell communication 34.7826 5 no
GO:0006996 organelle organization 33.3333 4 yes
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0048584 positive regulation of response to stimulus 33.3333 4 no
GO:0022607 cellular component assembly 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 31.8841 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 30.4348 5 no
GO:0009894 regulation of catabolic process 30.4348 4 no
GO:0015031 protein transport 28.9855 4 yes
GO:0006796 phosphate-containing compound metabolic process 28.9855 4 no
GO:0051130 positive regulation of cellular component organization 28.9855 5 no
GO:1902531 regulation of intracellular signal transduction 28.9855 5 no
GO:0031399 regulation of protein modification process 28.9855 6 no
GO:0031324 negative regulation of cellular metabolic process 28.9855 5 no
GO:0010648 negative regulation of cell communication 27.5362 5 no
GO:0023057 negative regulation of signaling 27.5362 4 no
GO:0009891 positive regulation of biosynthetic process 26.0870 5 no
GO:0042127 regulation of cell population proliferation 26.0870 4 no
GO:0071310 cellular response to organic substance 26.0870 4 no
GO:0051252 regulation of RNA metabolic process 26.0870 5 no
GO:0032880 regulation of protein localization 26.0870 5 no
GO:0060341 regulation of cellular localization 26.0870 4 no
GO:0006886 intracellular protein transport 24.6377 4 yes
GO:0009968 negative regulation of signal transduction 24.6377 5 no
GO:0031328 positive regulation of cellular biosynthetic process 24.6377 6 no
GO:0042981 regulation of apoptotic process 24.6377 5 no
GO:0043067 regulation of programmed cell death 24.6377 4 no
GO:0048585 negative regulation of response to stimulus 24.6377 4 no
GO:0006355 regulation of DNA-templated transcription 24.6377 7 no
GO:0043933 protein-containing complex organization 24.6377 4 no
GO:2001141 regulation of RNA biosynthetic process 24.6377 6 no
GO:0009890 negative regulation of biosynthetic process 24.6377 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 24.6377 6 no
GO:0031327 negative regulation of cellular biosynthetic process 24.6377 6 no
GO:0010557 positive regulation of macromolecule biosynthetic process 23.1884 6 no
GO:0019220 regulation of phosphate metabolic process 23.1884 6 no
GO:0051174 regulation of phosphorus metabolic process 23.1884 5 no
GO:0033043 regulation of organelle organization 23.1884 5 no
GO:1901701 cellular response to oxygen-containing compound 21.7391 4 no
GO:1902533 positive regulation of intracellular signal transduction 21.7391 6 no
GO:0044087 regulation of cellular component biogenesis 21.7391 4 no
GO:0051248 negative regulation of protein metabolic process 21.7391 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.2899 5 no
GO:0031401 positive regulation of protein modification process 20.2899 7 no
GO:0051049 regulation of transport 20.2899 4 no
GO:0010038 response to metal ion 11.5942 4 yes
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 10.1449 4 yes
GO:0035459 vesicle cargo loading 8.6957 4 yes
GO:0090110 COPII-coated vesicle cargo loading 8.6957 4 yes
GO:0051592 response to calcium ion 4.3478 5 yes
GO:0007029 endoplasmic reticulum organization 2.8986 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SC31A_HUMAN [view entry] [view interactions] Low throughput yes yes
PDCD6_HUMAN [view interactions] Low throughput no no
SEC13_HUMAN [view entry] [view interactions] Low throughput yes yes
SC23A_HUMAN [view entry] [view interactions] Low throughput yes yes
ALG2_HUMAN [view interactions] Low throughput no yes
STAM1_HUMAN [view interactions] Low throughput no yes
STAM2_HUMAN [view interactions] Low throughput no yes
KLH12_HUMAN [view interactions] Low throughput no no
ARI1_HUMAN [view interactions] Low throughput no yes
UBP8_HUMAN [view entry] [view interactions] Low throughput yes no
DHX15_HUMAN [view interactions] High throughput no yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
PNCB_HUMAN [view interactions] High throughput no no
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
TBCA_HUMAN [view interactions] High throughput no yes
TPD54_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
FCL_HUMAN [view interactions] High throughput no yes
ELOB_HUMAN [view interactions] High throughput no no
RT15_HUMAN [view interactions] High throughput no yes
RL35A_HUMAN [view entry] [view interactions] High throughput yes no
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
RLA2_HUMAN [view entry] [view interactions] High throughput yes yes
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
PEPL_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
PLST_HUMAN [view interactions] High throughput no yes
IDE_HUMAN [view interactions] High throughput no yes
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
AMRP_HUMAN [view interactions] High throughput no yes
RIR2_HUMAN [view interactions] High throughput no no
ARRB1_HUMAN [view entry] [view interactions] High throughput yes yes
AP1S1_HUMAN [view entry] [view interactions] High throughput yes yes
PSME1_HUMAN [view interactions] High throughput no yes
QRIC1_HUMAN [view interactions] High throughput no yes
CARL1_HUMAN [view interactions] High throughput no yes
RHG17_HUMAN [view interactions] High throughput no no
WDFY1_HUMAN [view interactions] High throughput no yes
MA7D3_HUMAN [view interactions] High throughput no no
LS14A_HUMAN [view interactions] High throughput no yes
PLBL2_HUMAN [view interactions] High throughput no yes
GRPE2_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
ADSSP_HUMAN [view interactions] High throughput no yes
TRM1_HUMAN [view interactions] High throughput no yes
NUP50_HUMAN [view interactions] High throughput no yes
PSME2_HUMAN [view interactions] High throughput no no
TPRKB_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
CD2AP_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
RN183_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
B3GA1_HUMAN [view interactions] High throughput no yes
CAV1_HUMAN [view interactions] High throughput no no
RCAS1_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
ERGI2_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
3BHS7_HUMAN [view interactions] High throughput no no
NU155_HUMAN [view interactions] High throughput no yes
ZFPL1_HUMAN [view interactions] High throughput no yes
TMPS2_HUMAN [view interactions] High throughput no no
FURIN_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
SAR1B_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
TBK1_HUMAN [view entry] [view interactions] High throughput yes yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
PFD1_HUMAN [view interactions] High throughput no yes
TNNT1_HUMAN [view interactions] High throughput no no
MTR1B_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
TFG_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
VCAM1_HUMAN [view interactions] High throughput no no
LUZP1_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
SCYL1_HUMAN [view interactions] High throughput no yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
BICD1_HUMAN [view interactions] High throughput no yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
DYR1A_HUMAN [view interactions] High throughput no yes
REL_HUMAN [view interactions] High throughput no yes
APC_HUMAN [view entry] [view interactions] High throughput yes no
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
MYOM2_HUMAN [view interactions] High throughput no yes
UBAC1_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
LCOR_HUMAN [view interactions] High throughput no yes
TMM17_HUMAN [view interactions] High throughput no yes
BET1_HUMAN [view interactions] High throughput no no
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA8_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR4_HUMAN [view interactions] High throughput no no
VGFR3_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
LMTK1_HUMAN [view interactions] High throughput no yes
MUSK_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRA_HUMAN [view interactions] High throughput no no
RET_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
T22D2_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
FHL5_HUMAN [view interactions] High throughput no no
ITA4_HUMAN [view interactions] High throughput no no
STB5L_HUMAN [view interactions] High throughput no no
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
NOP14_HUMAN [view interactions] High throughput no yes
S23IP_HUMAN [view interactions] High throughput no yes
NOC4L_HUMAN [view interactions] High throughput no no
GNPI1_HUMAN [view interactions] High throughput no yes
GRDN_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
BRCA1_HUMAN [view interactions] High throughput no yes
PEF1_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
SC23B_HUMAN [view interactions] High throughput no yes
SC24C_HUMAN [view entry] [view interactions] High throughput yes yes
SC24D_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
MRP6_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
AKT3_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RIN3_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
GORS1_HUMAN [view interactions] High throughput no yes
RPA49_HUMAN [view interactions] High throughput no yes
RAB14_HUMAN [view entry] [view interactions] High throughput yes yes
MOES_HUMAN [view entry] [view interactions] High throughput yes no
PGTA_HUMAN [view interactions] High throughput no yes
SPTC1_HUMAN [view interactions] High throughput no yes
TMEDA_HUMAN [view interactions] High throughput no yes
MYCN_HUMAN [view interactions] High throughput no no
TLS1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
GATA4_HUMAN [view interactions] High throughput no no
BHE40_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP48_HUMAN [view interactions] High throughput no yes
MYO10_HUMAN [view interactions] High throughput no no
ARF1_HUMAN [view entry] [view interactions] High throughput yes yes
DPOE3_HUMAN [view interactions] High throughput no yes
TBL1R_HUMAN [view interactions] High throughput no yes
IF2B1_HUMAN [view interactions] High throughput no no
DEPD5_HUMAN [view interactions] High throughput no yes
BAZ1A_HUMAN [view interactions] High throughput no no
ARL5A_HUMAN [view interactions] High throughput no yes
BMI1_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
MTF2_HUMAN [view interactions] High throughput no no
MA1A1_HUMAN [view interactions] High throughput no yes
NCOR1_HUMAN [view interactions] High throughput no yes
MA2A1_HUMAN [view interactions] High throughput no no
S39A9_HUMAN [view interactions] High throughput no yes
TPC12_HUMAN [view interactions] High throughput no yes
TPC10_HUMAN [view interactions] High throughput no no
GNT2A_HUMAN [view interactions] High throughput no yes
CARM1_HUMAN [view interactions] High throughput no yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
ARFG2_HUMAN [view entry] [view interactions] High throughput yes yes
SC24B_HUMAN [view interactions] High throughput no yes
ZNT5_HUMAN [view interactions] High throughput no yes
UB2J1_HUMAN [view interactions] High throughput no yes
TPC13_HUMAN [view interactions] High throughput no yes
VPS51_HUMAN [view interactions] High throughput no yes
HDAC8_HUMAN [view interactions] High throughput no yes
DCAF7_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
ACATN_HUMAN [view interactions] High throughput no yes
VPS45_HUMAN [view entry] [view interactions] High throughput yes yes
MPRI_HUMAN [view interactions] High throughput no yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
TPC11_HUMAN [view interactions] High throughput no no
VPS53_HUMAN [view entry] [view interactions] High throughput yes yes
TPPC5_HUMAN [view interactions] High throughput no yes
RABX5_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
TFE2_HUMAN [view interactions] High throughput no no
MA1B1_HUMAN [view interactions] High throughput no yes
B3GN2_HUMAN [view interactions] High throughput no yes
RICTR_HUMAN [view interactions] High throughput no yes
SC24A_HUMAN [view interactions] High throughput no no
S39A7_HUMAN [view interactions] High throughput no yes
MOGS_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
TPC2A_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
TPC2L_HUMAN [view interactions] High throughput no yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
GBF1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
ARMT1_HUMAN [view interactions] High throughput no yes
VATC1_HUMAN [view entry] [view interactions] High throughput yes yes
ENOG_HUMAN [view entry] [view interactions] High throughput yes yes
FPPS_HUMAN [view entry] [view interactions] High throughput yes yes
NUD13_HUMAN [view interactions] High throughput no no
SSDH_HUMAN [view entry] [view interactions] High throughput yes yes
VATD_HUMAN [view entry] [view interactions] High throughput yes yes
CBS_HUMAN [view interactions] High throughput no yes
CGL_HUMAN [view interactions] High throughput no yes
CYB5B_HUMAN [view entry] [view interactions] High throughput yes yes