CLUS_HUMAN
Does not affect caspase or BAX-mediated intrinsic apoptosis and TNF-induced NF-kappa-B-activity (PubMed). Promotes cell death through interaction with BCL2L1 that releases and activates BAX (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CLUS_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 32.9114 | 4 | no |
| GO:0046872 | metal ion binding | 32.9114 | 5 | no |
| GO:0000166 | nucleotide binding | 27.8481 | 4 | no |
| GO:0043168 | anion binding | 27.8481 | 4 | no |
| GO:0003723 | RNA binding | 27.8481 | 4 | no |
| GO:0017076 | purine nucleotide binding | 26.5823 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 26.5823 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.3165 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 24.0506 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 24.0506 | 5 | no |
| GO:0005524 | ATP binding | 22.7848 | 5 | no |
| GO:0031625 | ubiquitin protein ligase binding | 17.7215 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 17.7215 | 4 | yes |
| GO:0048156 | tau protein binding | 10.1266 | 4 | yes |
| GO:0070325 | lipoprotein particle receptor binding | 5.0633 | 4 | yes |
| GO:0050750 | low-density lipoprotein particle receptor binding | 3.7975 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CLUS_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 67.0886 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 60.7595 | 4 | yes |
| GO:0010646 | regulation of cell communication | 58.2278 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 58.2278 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 58.2278 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 58.2278 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 55.6962 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 55.6962 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.6329 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 50.6329 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 46.8354 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 45.5696 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 45.5696 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 44.3038 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 44.3038 | 5 | yes |
| GO:0010468 | regulation of gene expression | 43.0380 | 6 | yes |
| GO:0022607 | cellular component assembly | 43.0380 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 43.0380 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 37.9747 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 37.9747 | 4 | yes |
| GO:0006996 | organelle organization | 36.7089 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 36.7089 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 36.7089 | 6 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 36.7089 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 35.4430 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 35.4430 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 35.4430 | 5 | yes |
| GO:0008104 | protein localization | 34.1772 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 32.9114 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 31.6456 | 6 | no |
| GO:0009894 | regulation of catabolic process | 31.6456 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.6456 | 6 | yes |
| GO:0042981 | regulation of apoptotic process | 31.6456 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 31.6456 | 4 | yes |
| GO:0051049 | regulation of transport | 31.6456 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 30.3797 | 5 | yes |
| GO:0080134 | regulation of response to stress | 30.3797 | 4 | yes |
| GO:0036211 | protein modification process | 29.1139 | 4 | no |
| GO:0043412 | macromolecule modification | 29.1139 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 29.1139 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 29.1139 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 29.1139 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 27.8481 | 5 | no |
| GO:0043933 | protein-containing complex organization | 27.8481 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 27.8481 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 26.5823 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.5823 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.5823 | 6 | no |
| GO:0030162 | regulation of proteolysis | 26.5823 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 26.5823 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 26.5823 | 6 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 25.3165 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 25.3165 | 7 | no |
| GO:0032101 | regulation of response to external stimulus | 25.3165 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.3165 | 7 | yes |
| GO:0009968 | negative regulation of signal transduction | 25.3165 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 25.3165 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 25.3165 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 25.3165 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 25.3165 | 4 | yes |
| GO:0071702 | organic substance transport | 25.3165 | 4 | yes |
| GO:0030030 | cell projection organization | 24.0506 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 24.0506 | 7 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.7848 | 7 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 22.7848 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 22.7848 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.7848 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.7848 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.7848 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.7848 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 22.7848 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 22.7848 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.5190 | 4 | no |
| GO:0051338 | regulation of transferase activity | 21.5190 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 21.5190 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 21.5190 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 21.5190 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 21.5190 | 7 | yes |
| GO:0043066 | negative regulation of apoptotic process | 21.5190 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 21.5190 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 20.2532 | 7 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.2532 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.2532 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.2532 | 4 | no |
| GO:0033043 | regulation of organelle organization | 20.2532 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 20.2532 | 5 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.2532 | 6 | yes |
| GO:0009896 | positive regulation of catabolic process | 18.9873 | 5 | yes |
| GO:0015031 | protein transport | 18.9873 | 4 | yes |
| GO:0051050 | positive regulation of transport | 17.7215 | 4 | yes |
| GO:0033365 | protein localization to organelle | 16.4557 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 16.4557 | 4 | yes |
| GO:0080135 | regulation of cellular response to stress | 16.4557 | 4 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 16.4557 | 6 | yes |
| GO:0042176 | regulation of protein catabolic process | 15.1899 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 15.1899 | 5 | yes |
| GO:0045862 | positive regulation of proteolysis | 15.1899 | 7 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 15.1899 | 7 | yes |
| GO:0001817 | regulation of cytokine production | 13.9241 | 4 | yes |
| GO:0043065 | positive regulation of apoptotic process | 13.9241 | 6 | yes |
| GO:0043068 | positive regulation of programmed cell death | 13.9241 | 5 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 13.9241 | 5 | yes |
| GO:0002684 | positive regulation of immune system process | 12.6582 | 4 | yes |
| GO:0006886 | intracellular protein transport | 12.6582 | 4 | yes |
| GO:0050821 | protein stabilization | 12.6582 | 4 | yes |
| GO:0061024 | membrane organization | 12.6582 | 4 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 11.3924 | 5 | yes |
| GO:0007005 | mitochondrion organization | 11.3924 | 5 | yes |
| GO:0030100 | regulation of endocytosis | 11.3924 | 5 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 11.3924 | 5 | yes |
| GO:0050776 | regulation of immune response | 11.3924 | 4 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 11.3924 | 5 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 10.1266 | 6 | yes |
| GO:0043523 | regulation of neuron apoptotic process | 10.1266 | 6 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 10.1266 | 6 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 10.1266 | 6 | yes |
| GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 10.1266 | 8 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 8.8608 | 6 | yes |
| GO:0001819 | positive regulation of cytokine production | 8.8608 | 5 | yes |
| GO:0010639 | negative regulation of organelle organization | 8.8608 | 6 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 8.8608 | 6 | yes |
| GO:0045807 | positive regulation of endocytosis | 8.8608 | 5 | yes |
| GO:0050778 | positive regulation of immune response | 8.8608 | 5 | yes |
| GO:0072594 | establishment of protein localization to organelle | 8.8608 | 4 | yes |
| GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 7.5949 | 6 | yes |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 7.5949 | 6 | yes |
| GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 7.5949 | 7 | yes |
| GO:0007034 | vacuolar transport | 7.5949 | 4 | yes |
| GO:0007041 | lysosomal transport | 7.5949 | 5 | yes |
| GO:0032680 | regulation of tumor necrosis factor production | 7.5949 | 6 | yes |
| GO:0140546 | defense response to symbiont | 7.5949 | 4 | yes |
| GO:1901800 | positive regulation of proteasomal protein catabolic process | 7.5949 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 7.5949 | 6 | yes |
| GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 7.5949 | 5 | yes |
| GO:0001774 | microglial cell activation | 6.3291 | 4 | yes |
| GO:0010821 | regulation of mitochondrion organization | 6.3291 | 6 | yes |
| GO:0015850 | organic hydroxy compound transport | 6.3291 | 5 | yes |
| GO:0032760 | positive regulation of tumor necrosis factor production | 6.3291 | 7 | yes |
| GO:0034248 | regulation of amide metabolic process | 6.3291 | 4 | yes |
| GO:0042116 | macrophage activation | 6.3291 | 4 | yes |
| GO:0048259 | regulation of receptor-mediated endocytosis | 6.3291 | 6 | yes |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 6.3291 | 4 | yes |
| GO:0051131 | chaperone-mediated protein complex assembly | 6.3291 | 6 | yes |
| GO:1902904 | negative regulation of supramolecular fiber organization | 6.3291 | 6 | yes |
| GO:1903557 | positive regulation of tumor necrosis factor superfamily cytokine production | 6.3291 | 6 | yes |
| GO:1905897 | regulation of response to endoplasmic reticulum stress | 6.3291 | 5 | yes |
| GO:0006605 | protein targeting | 5.0633 | 4 | yes |
| GO:0006869 | lipid transport | 5.0633 | 5 | yes |
| GO:0007009 | plasma membrane organization | 5.0633 | 5 | yes |
| GO:0031333 | negative regulation of protein-containing complex assembly | 5.0633 | 6 | yes |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 5.0633 | 7 | yes |
| GO:0034249 | negative regulation of amide metabolic process | 5.0633 | 5 | yes |
| GO:0043524 | negative regulation of neuron apoptotic process | 5.0633 | 7 | yes |
| GO:0045428 | regulation of nitric oxide biosynthetic process | 5.0633 | 5 | yes |
| GO:0045429 | positive regulation of nitric oxide biosynthetic process | 5.0633 | 6 | yes |
| GO:0048260 | positive regulation of receptor-mediated endocytosis | 5.0633 | 6 | yes |
| GO:0080164 | regulation of nitric oxide metabolic process | 5.0633 | 4 | yes |
| GO:0090199 | regulation of release of cytochrome c from mitochondria | 5.0633 | 7 | yes |
| GO:0097193 | intrinsic apoptotic signaling pathway | 5.0633 | 4 | yes |
| GO:1902003 | regulation of amyloid-beta formation | 5.0633 | 5 | yes |
| GO:1902430 | negative regulation of amyloid-beta formation | 5.0633 | 6 | yes |
| GO:1902991 | regulation of amyloid precursor protein catabolic process | 5.0633 | 6 | yes |
| GO:1902992 | negative regulation of amyloid precursor protein catabolic process | 5.0633 | 7 | yes |
| GO:1903573 | negative regulation of response to endoplasmic reticulum stress | 5.0633 | 5 | yes |
| GO:1904407 | positive regulation of nitric oxide metabolic process | 5.0633 | 5 | yes |
| GO:2001235 | positive regulation of apoptotic signaling pathway | 3.7975 | 6 | yes |
| GO:0006958 | complement activation, classical pathway | 3.7975 | 4 | yes |
| GO:0008637 | apoptotic mitochondrial changes | 3.7975 | 6 | yes |
| GO:0015918 | sterol transport | 3.7975 | 6 | yes |
| GO:0030301 | cholesterol transport | 3.7975 | 7 | yes |
| GO:0032286 | central nervous system myelin maintenance | 3.7975 | 7 | yes |
| GO:0043217 | myelin maintenance | 3.7975 | 6 | yes |
| GO:0090201 | negative regulation of release of cytochrome c from mitochondria | 3.7975 | 7 | yes |
| GO:1900221 | regulation of amyloid-beta clearance | 3.7975 | 4 | yes |
| GO:1905906 | regulation of amyloid fibril formation | 3.7975 | 6 | yes |
| GO:1905908 | positive regulation of amyloid fibril formation | 3.7975 | 7 | yes |
| GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway | 2.5316 | 7 | yes |
| GO:0001836 | release of cytochrome c from mitochondria | 2.5316 | 7 | yes |
| GO:0006622 | protein targeting to lysosome | 2.5316 | 6 | yes |
| GO:0006623 | protein targeting to vacuole | 2.5316 | 5 | yes |
| GO:0017038 | protein import | 2.5316 | 5 | yes |
| GO:0034250 | positive regulation of amide metabolic process | 2.5316 | 5 | yes |
| GO:0043691 | reverse cholesterol transport | 2.5316 | 8 | yes |
| GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 2.5316 | 5 | yes |
| GO:0051788 | response to misfolded protein | 2.5316 | 4 | yes |
| GO:0061462 | protein localization to lysosome | 2.5316 | 7 | yes |
| GO:0061517 | macrophage proliferation | 2.5316 | 4 | yes |
| GO:0061518 | microglial cell proliferation | 2.5316 | 4 | yes |
| GO:0061740 | protein targeting to lysosome involved in chaperone-mediated autophagy | 2.5316 | 7 | yes |
| GO:0071211 | protein targeting to vacuole involved in autophagy | 2.5316 | 6 | yes |
| GO:0072665 | protein localization to vacuole | 2.5316 | 6 | yes |
| GO:0072666 | establishment of protein localization to vacuole | 2.5316 | 5 | yes |
| GO:0090083 | regulation of inclusion body assembly | 2.5316 | 5 | yes |
| GO:0090261 | positive regulation of inclusion body assembly | 2.5316 | 6 | yes |
| GO:1902004 | positive regulation of amyloid-beta formation | 2.5316 | 6 | yes |
| GO:1902229 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 2.5316 | 5 | yes |
| GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 2.5316 | 6 | yes |
| GO:1902847 | regulation of neuronal signal transduction | 2.5316 | 5 | yes |
| GO:1902993 | positive regulation of amyloid precursor protein catabolic process | 2.5316 | 7 | yes |
| GO:1902996 | regulation of neurofibrillary tangle assembly | 2.5316 | 6 | yes |
| GO:1902998 | positive regulation of neurofibrillary tangle assembly | 2.5316 | 7 | yes |
| GO:1905907 | negative regulation of amyloid fibril formation | 2.5316 | 7 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CO8B_HUMAN | [view interactions] | Low throughput | no | no |
| CO7_HUMAN | [view interactions] | Low throughput | no | no |
| CO9_HUMAN | [view interactions] | Low throughput | no | no |
| LRP2_HUMAN | [view interactions] | Low throughput | no | no |
| SYVN1_HUMAN | [view interactions] | Low throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| TTHY_HUMAN | [view interactions] | Low throughput | no | no |
| ELN_HUMAN | [view interactions] | Low throughput | no | no |
| MSRB1_HUMAN | [view interactions] | Low throughput | no | no |
| LYSC_HUMAN | [view interactions] | Low throughput | no | no |
| PROP_HUMAN | [view interactions] | Low throughput | no | no |
| IL24_HUMAN | [view interactions] | Low throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LEP_HUMAN | [view interactions] | Low throughput | no | no |
| VLDLR_HUMAN | [view interactions] | Low throughput | no | yes |
| TREM2_HUMAN | [view interactions] | Low throughput | no | yes |
| LRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYCN_HUMAN | [view interactions] | Low throughput | no | no |
| KDM1A_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLUS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| XRCC6_HUMAN | [view interactions] | Low throughput | no | yes |
| TGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| COMD1_HUMAN | [view interactions] | Low throughput | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZWINT_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KTNA1_HUMAN | [view interactions] | Low throughput | no | yes |
| SKAP_HUMAN | [view interactions] | Low throughput | no | yes |
| CBY1_HUMAN | [view interactions] | Low throughput | no | no |
| CLUA1_HUMAN | [view interactions] | Low throughput | no | yes |
| PACR_HUMAN | [view interactions] | Low throughput | no | no |
| EIF3F_HUMAN | [view interactions] | Low throughput | no | yes |
| MMP25_HUMAN | [view interactions] | Low throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
| BAX_HUMAN | [view interactions] | Low throughput | no | yes |
| CD209_HUMAN | [view interactions] | Low throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| B3AT_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HBA_HUMAN | [view interactions] | Low throughput | no | no |
| ATP7B_HUMAN | [view interactions] | Low throughput | no | no |
| ATP7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HYALP_HUMAN | [view interactions] | Low throughput | no | no |
| CH60_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PON1_HUMAN | [view interactions] | Low throughput | no | no |
| BIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HYOU1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRFL_HUMAN | [view interactions] | Low throughput | no | no |
| EPPI_HUMAN | [view interactions] | Low throughput | no | no |
| SEMG1_HUMAN | [view interactions] | Low throughput | no | no |
| ATG3_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MMP9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VEGFA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLXA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRP1B_HUMAN | [view interactions] | Low throughput | no | yes |
| TENA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KLF5_HUMAN | [view interactions] | Low throughput | no | yes |
| ULK1_HUMAN | [view interactions] | Low throughput | no | no |
| PACA_HUMAN | [view interactions] | Low throughput | no | no |
| TWST1_HUMAN | [view interactions] | Low throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SOAT2_HUMAN | [view interactions] | Low throughput | no | no |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDR1_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| APOA1_HUMAN | [view interactions] | High throughput | no | no |
| IGHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGHG1_HUMAN | [view interactions] | High throughput | no | no |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP2E1_HUMAN | [view interactions] | High throughput | no | no |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| KLF11_HUMAN | [view interactions] | High throughput | no | no |
| CTIP_HUMAN | [view interactions] | High throughput | no | no |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
| NUCB2_HUMAN | [view interactions] | High throughput | no | yes |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APMAP_HUMAN | [view interactions] | High throughput | no | yes |
| STAG2_HUMAN | [view interactions] | High throughput | no | yes |
| ABCA6_HUMAN | [view interactions] | High throughput | no | no |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| F169A_HUMAN | [view interactions] | High throughput | no | yes |
| PPARG_HUMAN | [view interactions] | High throughput | no | yes |
| MOCOS_HUMAN | [view interactions] | High throughput | no | no |
| CDK19_HUMAN | [view interactions] | High throughput | no | yes |
| HPTR_HUMAN | [view interactions] | High throughput | no | no |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| BIG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| TEBP_HUMAN | [view interactions] | High throughput | no | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MO4L1_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMNL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADHX_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
| SYDC_HUMAN | [view interactions] | High throughput | no | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRE2_HUMAN | [view interactions] | High throughput | no | yes |
| MYT1L_HUMAN | [view interactions] | High throughput | no | no |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| BICRL_HUMAN | [view interactions] | High throughput | no | yes |
| FRIH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| BEX3_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA4_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLDN_HUMAN | [view interactions] | High throughput | no | no |
| CE85L_HUMAN | [view interactions] | High throughput | no | yes |
| ASB3_HUMAN | [view interactions] | High throughput | no | yes |
| PAX6_HUMAN | [view interactions] | High throughput | no | no |
| CSN7A_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG4_HUMAN | [view interactions] | High throughput | no | yes |
| PI42A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSD3_HUMAN | [view interactions] | High throughput | no | yes |
| INT10_HUMAN | [view interactions] | High throughput | no | yes |
| RN220_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| SOS2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| QTRT2_HUMAN | [view interactions] | High throughput | no | yes |
| SPEF2_HUMAN | [view interactions] | High throughput | no | no |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| SPRL1_HUMAN | [view interactions] | High throughput | no | no |
| ZN514_HUMAN | [view interactions] | High throughput | no | yes |
| VP9D1_HUMAN | [view interactions] | High throughput | no | no |
| ZN592_HUMAN | [view interactions] | High throughput | no | yes |
| BTG3_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| ETS2_HUMAN | [view interactions] | High throughput | no | no |
| HUNK_HUMAN | [view interactions] | High throughput | no | yes |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| LCOR_HUMAN | [view interactions] | High throughput | no | yes |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| MDM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZNF24_HUMAN | [view interactions] | High throughput | no | yes |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| RSPH1_HUMAN | [view interactions] | High throughput | no | no |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RPE_HUMAN | [view interactions] | High throughput | no | yes |
| DPA1_HUMAN | [view interactions] | High throughput | no | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| CCND3_HUMAN | [view interactions] | High throughput | no | no |
| DPPA4_HUMAN | [view interactions] | High throughput | no | no |
| I20RB_HUMAN | [view interactions] | High throughput | no | no |
| SUMF2_HUMAN | [view interactions] | High throughput | no | yes |
| GP180_HUMAN | [view interactions] | High throughput | no | yes |
| GINM1_HUMAN | [view interactions] | High throughput | no | yes |
| CAB45_HUMAN | [view interactions] | High throughput | no | no |
| MMP3_HUMAN | [view interactions] | High throughput | no | no |
| RASF7_HUMAN | [view interactions] | High throughput | no | no |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| RNS13_HUMAN | [view interactions] | High throughput | no | no |
| IFNA5_HUMAN | [view interactions] | High throughput | no | no |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| ARMC6_HUMAN | [view interactions] | High throughput | no | yes |
| GCP5_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SETX_HUMAN | [view interactions] | High throughput | no | yes |
| GPAT1_HUMAN | [view interactions] | High throughput | no | no |
| BUB1_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| CEP72_HUMAN | [view interactions] | High throughput | no | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| SDK2_HUMAN | [view interactions] | High throughput | no | no |
| AT2B2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TEN3_HUMAN | [view interactions] | High throughput | no | yes |
| FAT4_HUMAN | [view interactions] | High throughput | no | yes |
| FBX27_HUMAN | [view interactions] | High throughput | no | yes |
| ZNG1C_HUMAN | [view interactions] | High throughput | no | yes |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| DHX57_HUMAN | [view interactions] | High throughput | no | no |
| ITA8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EDEM2_HUMAN | [view interactions] | High throughput | no | yes |
| MANEA_HUMAN | [view interactions] | High throughput | no | yes |
| DDX31_HUMAN | [view interactions] | High throughput | no | no |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| EXTL2_HUMAN | [view interactions] | High throughput | no | yes |
| TOR1A_HUMAN | [view interactions] | High throughput | no | yes |
| MA1A1_HUMAN | [view interactions] | High throughput | no | yes |
| TNFL9_HUMAN | [view interactions] | High throughput | no | no |
| PCYXL_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MA1A2_HUMAN | [view interactions] | High throughput | no | yes |
| CELR1_HUMAN | [view interactions] | High throughput | no | no |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXD11_HUMAN | [view interactions] | High throughput | no | yes |
| INT5_HUMAN | [view interactions] | High throughput | no | no |
| PCYOX_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR9_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| LMA2L_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| BMP4_HUMAN | [view interactions] | High throughput | no | no |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COMP_HUMAN | [view interactions] | High throughput | no | no |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| PHIP_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| VTDB_HUMAN | [view interactions] | High throughput | no | yes |
| CERU_HUMAN | [view interactions] | High throughput | no | no |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| PROL4_HUMAN | [view interactions] | High throughput | no | no |
| A1AT_HUMAN | [view interactions] | High throughput | no | no |
| STAT_HUMAN | [view interactions] | High throughput | no | no |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FCGRN_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIRB4_HUMAN | [view interactions] | High throughput | no | no |
| MK09_HUMAN | [view interactions] | High throughput | no | yes |
| MICB_HUMAN | [view interactions] | High throughput | no | no |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTL1_HUMAN | [view interactions] | High throughput | no | no |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| CP4F8_HUMAN | [view interactions] | High throughput | no | no |
| AP2D_HUMAN | [view interactions] | High throughput | no | no |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| ZN451_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEAM8_HUMAN | [view interactions] | High throughput | no | no |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| CXB5_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOG8A_HUMAN | [view interactions] | High throughput | no | no |
| DOCK6_HUMAN | [view interactions] | High throughput | no | yes |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| MAK_HUMAN | [view interactions] | High throughput | no | no |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| CCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| DDR2_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |