KS6A5_HUMAN
Evidence for PS localization
Functions
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin (PubMed, PubMed). Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression (PubMed, PubMed). In skeletal myoblasts is required for phosphorylation of RELA at Ser-276 during oxidative stress (PubMed). In erythropoietin-stimulated cells, is necessary for the Ser-727 phosphorylation of STAT3 and regulation of its transcriptional potential (PubMed). Phosphorylates ETV1/ER81 at Ser-191 and Ser-216, and thereby regulates its ability to stimulate transcription, which may be important during development and breast tumor formation (PubMed). Directly represses transcription via phosphorylation of Ser-1 of histone H2A (PubMed). Phosphorylates Ser-10 of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN (PubMed). May also phosphorylate Ser-28 of histone H3 (PubMed). Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14) (PubMed). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro-inflammatory cytokines . Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti-inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors . Plays a role in neuronal cell death by mediating the downstream effects of excitotoxic injury . Phosphorylates TRIM7 at Ser-107 in response to growth factor signaling via the MEK/ERK pathway, thereby stimulating its ubiquitin ligase activity (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002944 | DOC_MAPK_RevD_3 | DOC | 730 | 744 | - |
| ELMI003708 | LIG_SH2_STAP1 | LIG | 423 | 427 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in KS6A5_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 36.5854 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 36.5854 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 36.5854 | 4 | yes |
| GO:0005524 | ATP binding | 26.8293 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 26.8293 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 26.8293 | 5 | yes |
| GO:0046872 | metal ion binding | 24.3902 | 4 | yes |
| GO:0003723 | RNA binding | 21.9512 | 4 | no |
| GO:0019900 | kinase binding | 21.9512 | 4 | no |
| GO:0019901 | protein kinase binding | 21.9512 | 5 | no |
| GO:0004674 | protein serine/threonine kinase activity | 14.6341 | 4 | yes |
| GO:0016301 | kinase activity | 14.6341 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 14.6341 | 4 | yes |
| GO:0004712 | protein serine/threonine/tyrosine kinase activity | 12.1951 | 4 | yes |
| GO:0106310 | protein serine kinase activity | 12.1951 | 4 | yes |
| GO:0000287 | magnesium ion binding | 4.8780 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in KS6A5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 68.2927 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 58.5366 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 56.0976 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 56.0976 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.6585 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 53.6585 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 51.2195 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 48.7805 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 46.3415 | 5 | yes |
| GO:0010468 | regulation of gene expression | 43.9024 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 43.9024 | 5 | yes |
| GO:0010646 | regulation of cell communication | 43.9024 | 4 | no |
| GO:0006996 | organelle organization | 43.9024 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 41.4634 | 5 | yes |
| GO:0022607 | cellular component assembly | 41.4634 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 41.4634 | 4 | no |
| GO:0051049 | regulation of transport | 36.5854 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 36.5854 | 6 | yes |
| GO:0009966 | regulation of signal transduction | 36.5854 | 4 | no |
| GO:0071310 | cellular response to organic substance | 34.1463 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 34.1463 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 34.1463 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.1463 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 34.1463 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 31.7073 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.7073 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 31.7073 | 4 | yes |
| GO:0036211 | protein modification process | 31.7073 | 4 | yes |
| GO:0043412 | macromolecule modification | 31.7073 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 31.7073 | 4 | no |
| GO:0010941 | regulation of cell death | 31.7073 | 4 | no |
| GO:0080134 | regulation of response to stress | 29.2683 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 29.2683 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 29.2683 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.2683 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 29.2683 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 29.2683 | 6 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.2683 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 29.2683 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 29.2683 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.2683 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 29.2683 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 29.2683 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 26.8293 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 26.8293 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.8293 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 26.8293 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.8293 | 6 | yes |
| GO:0030030 | cell projection organization | 26.8293 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.8293 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 26.8293 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 26.8293 | 5 | no |
| GO:0023056 | positive regulation of signaling | 26.8293 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 26.8293 | 4 | no |
| GO:0033043 | regulation of organelle organization | 26.8293 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.8293 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 24.3902 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.3902 | 6 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 24.3902 | 7 | yes |
| GO:0051252 | regulation of RNA metabolic process | 24.3902 | 5 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.3902 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 24.3902 | 6 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 24.3902 | 6 | no |
| GO:0042327 | positive regulation of phosphorylation | 24.3902 | 8 | no |
| GO:0043933 | protein-containing complex organization | 24.3902 | 4 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 24.3902 | 7 | no |
| GO:0065003 | protein-containing complex assembly | 24.3902 | 5 | no |
| GO:0006897 | endocytosis | 24.3902 | 5 | no |
| GO:0009894 | regulation of catabolic process | 24.3902 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 24.3902 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.3902 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.9512 | 4 | no |
| GO:0006468 | protein phosphorylation | 21.9512 | 5 | yes |
| GO:0016310 | phosphorylation | 21.9512 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 21.9512 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.9512 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 21.9512 | 4 | no |
| GO:0008104 | protein localization | 21.9512 | 4 | no |
| GO:0007010 | cytoskeleton organization | 21.9512 | 5 | no |
| GO:0032880 | regulation of protein localization | 21.9512 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.9512 | 4 | no |
| GO:0045597 | positive regulation of cell differentiation | 21.9512 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 19.5122 | 7 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 19.5122 | 7 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 19.5122 | 8 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 19.5122 | 6 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 19.5122 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 19.5122 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 19.5122 | 8 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 17.0732 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 17.0732 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 17.0732 | 5 | yes |
| GO:0031175 | neuron projection development | 17.0732 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 17.0732 | 6 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 17.0732 | 6 | yes |
| GO:0001817 | regulation of cytokine production | 14.6341 | 4 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 14.6341 | 7 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 14.6341 | 4 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 14.6341 | 6 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 14.6341 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 14.6341 | 8 | yes |
| GO:0010629 | negative regulation of gene expression | 12.1951 | 6 | yes |
| GO:0019221 | cytokine-mediated signaling pathway | 12.1951 | 4 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 9.7561 | 6 | yes |
| GO:0018209 | peptidyl-serine modification | 9.7561 | 6 | yes |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 9.7561 | 4 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 7.3171 | 4 | yes |
| GO:0007411 | axon guidance | 7.3171 | 8 | yes |
| GO:0031056 | regulation of histone modification | 7.3171 | 7 | yes |
| GO:0031058 | positive regulation of histone modification | 7.3171 | 8 | yes |
| GO:0035065 | regulation of histone acetylation | 7.3171 | 8 | yes |
| GO:0035066 | positive regulation of histone acetylation | 7.3171 | 9 | yes |
| GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 7.3171 | 5 | yes |
| GO:0070498 | interleukin-1-mediated signaling pathway | 7.3171 | 5 | yes |
| GO:0097485 | neuron projection guidance | 7.3171 | 7 | yes |
| GO:1901983 | regulation of protein acetylation | 7.3171 | 7 | yes |
| GO:1901985 | positive regulation of protein acetylation | 7.3171 | 8 | yes |
| GO:2000756 | regulation of peptidyl-lysine acetylation | 7.3171 | 8 | yes |
| GO:2000758 | positive regulation of peptidyl-lysine acetylation | 7.3171 | 9 | yes |
| GO:0001818 | negative regulation of cytokine production | 4.8780 | 5 | yes |
| GO:0006954 | inflammatory response | 4.8780 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 4.8780 | 5 | yes |
| GO:0038127 | ERBB signaling pathway | 4.8780 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SMCA4_HUMAN | [view interactions] | Low throughput | no | yes |
| RARA_HUMAN | [view interactions] | Low throughput | no | no |
| MK14_HUMAN | [view interactions] | Low throughput | no | yes |
| EGF_HUMAN | [view interactions] | Low throughput | no | no |
| ATF2_HUMAN | [view interactions] | Low throughput | no | yes |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MK11_HUMAN | [view interactions] | Low throughput | no | yes |
| BAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
| H31_HUMAN | [view interactions] | Low throughput | no | yes |
| H32_HUMAN | [view interactions] | Low throughput | no | yes |
| H2B2E_HUMAN | [view interactions] | Low throughput | no | yes |
| H4_HUMAN | [view interactions] | Low throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | Low throughput | no | yes |
| MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| H11_HUMAN | [view interactions] | Low throughput | no | no |
| ETV1_HUMAN | [view interactions] | Low throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATF1_HUMAN | [view interactions] | Low throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KDM3A_HUMAN | [view interactions] | Low throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAD2_HUMAN | [view interactions] | High throughput | no | no |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| RPAB1_HUMAN | [view interactions] | High throughput | no | yes |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| SCO2_HUMAN | [view interactions] | High throughput | no | no |
| PFD6_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT1_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| I17RB_HUMAN | [view interactions] | High throughput | no | no |
| ALG8_HUMAN | [view interactions] | High throughput | no | yes |
| GASP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| SPSB4_HUMAN | [view interactions] | High throughput | no | no |
| HIDE1_HUMAN | [view interactions] | High throughput | no | no |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| GGH_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4A_HUMAN | [view interactions] | High throughput | no | no |
| MK04_HUMAN | [view interactions] | High throughput | no | no |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| TMM25_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| THOC1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| MDFIC_HUMAN | [view interactions] | High throughput | no | yes |
| TXD11_HUMAN | [view interactions] | High throughput | no | yes |
| M3K20_HUMAN | [view interactions] | High throughput | no | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKTS1_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDAH2_HUMAN | [view interactions] | High throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERH_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| ITSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI1_HUMAN | [view interactions] | High throughput | no | yes |
| RAI1_HUMAN | [view interactions] | High throughput | no | yes |
| RN19A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROBO2_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD6_HUMAN | [view interactions] | High throughput | no | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| U119A_HUMAN | [view interactions] | High throughput | no | no |
| ZN775_HUMAN | [view interactions] | High throughput | no | no |
| HS904_HUMAN | [view interactions] | High throughput | no | no |
| RT18B_HUMAN | [view interactions] | High throughput | no | yes |
| RT17_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| RM27_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| CPVL_HUMAN | [view interactions] | High throughput | no | no |
| CLPB_HUMAN | [view interactions] | High throughput | no | yes |
| SIN3A_HUMAN | [view interactions] | High throughput | no | yes |
| RM24_HUMAN | [view interactions] | High throughput | no | yes |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEBP_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOS2_HUMAN | [view interactions] | High throughput | no | yes |
| TP53B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H31T_HUMAN | [view interactions] | Computational | no | yes |
| KS6A1_HUMAN | [view interactions] | Computational | no | yes |
| ATF6B_HUMAN | [view interactions] | Computational | no | yes |
| 4EBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H3C_HUMAN | [view interactions] | Computational | no | yes |
| H33_HUMAN | [view interactions] | Computational | no | yes |
| KS6A2_HUMAN | [view interactions] | Computational | no | yes |
| LPAR4_HUMAN | [view interactions] | Computational | no | no |
| ATF4_HUMAN | [view interactions] | Computational | no | no |
| MK12_HUMAN | [view interactions] | Computational | no | no |
| KS6A6_HUMAN | [view interactions] | Computational | no | yes |
| KS6A4_HUMAN | [view interactions] | Computational | no | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MK13_HUMAN | [view interactions] | Computational | no | yes |
| HMGN1_HUMAN | [view interactions] | Computational | no | yes |
| CBX3_HUMAN | [view interactions] | Computational | no | yes |