DHB12_HUMAN
Evidence for PS localization
Functions
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DHB12_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 32.4675 | 4 | no |
| GO:0043168 | anion binding | 32.4675 | 4 | no |
| GO:0017076 | purine nucleotide binding | 31.1688 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 29.8701 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.8701 | 4 | no |
| GO:0043169 | cation binding | 24.6753 | 4 | no |
| GO:0046872 | metal ion binding | 23.3766 | 5 | no |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 3.8961 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DHB12_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 53.2468 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 44.1558 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.1558 | 4 | no |
| GO:0008104 | protein localization | 42.8571 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 41.5584 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 41.5584 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.9610 | 4 | no |
| GO:0006996 | organelle organization | 37.6623 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.6623 | 4 | no |
| GO:0010646 | regulation of cell communication | 36.3636 | 4 | no |
| GO:0071702 | organic substance transport | 35.0649 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.0649 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.7662 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 33.7662 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 33.7662 | 4 | no |
| GO:0071705 | nitrogen compound transport | 32.4675 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.4675 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.1688 | 5 | no |
| GO:0010468 | regulation of gene expression | 31.1688 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 31.1688 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.8701 | 4 | no |
| GO:0023056 | positive regulation of signaling | 28.5714 | 4 | no |
| GO:0022607 | cellular component assembly | 27.2727 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 27.2727 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.2727 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.2727 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.2727 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
| GO:0015031 | protein transport | 25.9740 | 4 | no |
| GO:0031399 | regulation of protein modification process | 25.9740 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 25.9740 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 25.9740 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.6753 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.6753 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.6753 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.6753 | 5 | no |
| GO:0036211 | protein modification process | 24.6753 | 4 | no |
| GO:0043412 | macromolecule modification | 24.6753 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 24.6753 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.6753 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.3766 | 7 | no |
| GO:0009892 | negative regulation of metabolic process | 23.3766 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 23.3766 | 7 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.0779 | 6 | no |
| GO:0051049 | regulation of transport | 22.0779 | 4 | no |
| GO:0006915 | apoptotic process | 22.0779 | 4 | no |
| GO:0030030 | cell projection organization | 22.0779 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 22.0779 | 7 | no |
| GO:0033043 | regulation of organelle organization | 22.0779 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.0779 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.0779 | 4 | no |
| GO:0098657 | import into cell | 22.0779 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.7792 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.7792 | 6 | no |
| GO:0060341 | regulation of cellular localization | 20.7792 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.7792 | 7 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 18.1818 | 4 | yes |
| GO:0030155 | regulation of cell adhesion | 9.0909 | 4 | yes |
| GO:0045785 | positive regulation of cell adhesion | 7.7922 | 5 | yes |
| GO:0008610 | lipid biosynthetic process | 6.4935 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 6.4935 | 4 | yes |
| GO:0006631 | fatty acid metabolic process | 5.1948 | 4 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 5.1948 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 5.1948 | 5 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 5.1948 | 6 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 5.1948 | 4 | yes |
| GO:0043436 | oxoacid metabolic process | 5.1948 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 5.1948 | 4 | yes |
| GO:0006633 | fatty acid biosynthetic process | 3.8961 | 5 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 3.8961 | 6 | yes |
| GO:0016053 | organic acid biosynthetic process | 3.8961 | 4 | yes |
| GO:0046394 | carboxylic acid biosynthetic process | 3.8961 | 5 | yes |
| GO:0072330 | monocarboxylic acid biosynthetic process | 3.8961 | 6 | yes |
| GO:0090407 | organophosphate biosynthetic process | 3.8961 | 4 | yes |
| GO:0006163 | purine nucleotide metabolic process | 2.5974 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 2.5974 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 2.5974 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 2.5974 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 2.5974 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 2.5974 | 4 | yes |
| GO:0072521 | purine-containing compound metabolic process | 2.5974 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ILDR2_HUMAN | [view interactions] | Low throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JMJD4_HUMAN | [view interactions] | High throughput | no | no |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| VGFR1_HUMAN | [view interactions] | High throughput | no | no |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ELOV1_HUMAN | [view interactions] | High throughput | no | yes |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| RN157_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| HIF1A_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| CTCF_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOT1_HUMAN | [view interactions] | High throughput | no | no |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| RN170_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| TNFL8_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| NSDHL_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| CFAH_HUMAN | [view interactions] | High throughput | no | no |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| COPB_HUMAN | [view interactions] | High throughput | no | yes |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL36_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSRG_HUMAN | [view interactions] | High throughput | no | yes |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| TMCO1_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| CALR3_HUMAN | [view interactions] | High throughput | no | no |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| HDA11_HUMAN | [view interactions] | High throughput | no | no |
| S38A1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK07_HUMAN | [view interactions] | High throughput | no | yes |
| ELK1_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CNR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMC3_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4A4A_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JAK3_HUMAN | [view interactions] | High throughput | no | no |
| ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
| TSSK6_HUMAN | [view interactions] | High throughput | no | no |
| SRPK3_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |