Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MTAP2_HUMAN

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in MTAP2_HUMAN
GO:0043169 cation binding 37.6812 4 no
GO:0046872 metal ion binding 37.6812 5 no
GO:0019900 kinase binding 34.7826 4 no
GO:0019901 protein kinase binding 31.8841 5 no
GO:0043168 anion binding 28.9855 4 no
GO:0000166 nucleotide binding 24.6377 4 no
GO:0017076 purine nucleotide binding 24.6377 5 no
GO:0032555 purine ribonucleotide binding 24.6377 4 no
GO:0035639 purine ribonucleoside triphosphate binding 21.7391 4 no
GO:0030554 adenyl nucleotide binding 20.2899 6 no
GO:0032559 adenyl ribonucleotide binding 20.2899 5 no
GO:0003723 RNA binding 20.2899 4 no
GO:0015631 tubulin binding 14.4928 4 yes
GO:0048156 tau protein binding 14.4928 4 yes
GO:0008017 microtubule binding 8.6957 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MTAP2_HUMAN
GO:0048522 positive regulation of cellular process 65.2174 4 yes
GO:0048523 negative regulation of cellular process 63.7681 4 yes
GO:0010646 regulation of cell communication 59.4203 4 no
GO:0051128 regulation of cellular component organization 59.4203 4 yes
GO:0060255 regulation of macromolecule metabolic process 53.6232 4 no
GO:0031323 regulation of cellular metabolic process 53.6232 4 no
GO:0080090 regulation of primary metabolic process 52.1739 4 no
GO:0009966 regulation of signal transduction 47.8261 4 no
GO:0051246 regulation of protein metabolic process 44.9275 5 no
GO:0022607 cellular component assembly 44.9275 4 no
GO:0051049 regulation of transport 44.9275 4 yes
GO:0009893 positive regulation of metabolic process 39.1304 4 no
GO:0008104 protein localization 39.1304 4 no
GO:0006996 organelle organization 39.1304 4 yes
GO:0009892 negative regulation of metabolic process 37.6812 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.2319 5 no
GO:0009889 regulation of biosynthetic process 36.2319 4 no
GO:0010468 regulation of gene expression 36.2319 6 no
GO:0010556 regulation of macromolecule biosynthetic process 36.2319 5 no
GO:0031324 negative regulation of cellular metabolic process 36.2319 5 no
GO:0031326 regulation of cellular biosynthetic process 36.2319 5 no
GO:0030030 cell projection organization 36.2319 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 34.7826 5 no
GO:0031325 positive regulation of cellular metabolic process 34.7826 5 no
GO:0019220 regulation of phosphate metabolic process 34.7826 6 no
GO:0051174 regulation of phosphorus metabolic process 34.7826 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0050804 modulation of chemical synaptic transmission 33.3333 5 no
GO:0099177 regulation of trans-synaptic signaling 33.3333 4 no
GO:0042325 regulation of phosphorylation 31.8841 7 no
GO:0060341 regulation of cellular localization 31.8841 4 yes
GO:0120036 plasma membrane bounded cell projection organization 31.8841 5 yes
GO:0001932 regulation of protein phosphorylation 30.4348 7 no
GO:0043933 protein-containing complex organization 30.4348 4 no
GO:1902531 regulation of intracellular signal transduction 30.4348 5 no
GO:0023056 positive regulation of signaling 30.4348 4 no
GO:0048584 positive regulation of response to stimulus 30.4348 4 no
GO:0051050 positive regulation of transport 30.4348 4 yes
GO:0010647 positive regulation of cell communication 28.9855 5 no
GO:0031344 regulation of cell projection organization 28.9855 5 yes
GO:0044087 regulation of cellular component biogenesis 28.9855 4 yes
GO:0036211 protein modification process 27.5362 4 no
GO:0043412 macromolecule modification 27.5362 4 no
GO:0051130 positive regulation of cellular component organization 27.5362 5 no
GO:0051247 positive regulation of protein metabolic process 27.5362 6 no
GO:0010648 negative regulation of cell communication 27.5362 5 no
GO:0023057 negative regulation of signaling 27.5362 4 no
GO:0051248 negative regulation of protein metabolic process 27.5362 6 no
GO:0031175 neuron projection development 27.5362 6 yes
GO:0032880 regulation of protein localization 27.5362 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 27.5362 6 yes
GO:0034762 regulation of transmembrane transport 26.0870 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 26.0870 5 no
GO:0048585 negative regulation of response to stimulus 26.0870 4 no
GO:0065003 protein-containing complex assembly 26.0870 5 no
GO:0007010 cytoskeleton organization 26.0870 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 26.0870 4 yes
GO:0045595 regulation of cell differentiation 26.0870 4 yes
GO:0043549 regulation of kinase activity 24.6377 5 no
GO:0051338 regulation of transferase activity 24.6377 4 no
GO:0009968 negative regulation of signal transduction 24.6377 5 no
GO:0034330 cell junction organization 24.6377 4 no
GO:0050890 cognition 24.6377 4 no
GO:0051129 negative regulation of cellular component organization 24.6377 5 yes
GO:0051094 positive regulation of developmental process 23.1884 4 no
GO:0009890 negative regulation of biosynthetic process 23.1884 5 no
GO:0009891 positive regulation of biosynthetic process 23.1884 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 23.1884 6 no
GO:0031327 negative regulation of cellular biosynthetic process 23.1884 6 no
GO:0031328 positive regulation of cellular biosynthetic process 23.1884 6 no
GO:0006355 regulation of DNA-templated transcription 23.1884 7 no
GO:0051252 regulation of RNA metabolic process 23.1884 5 no
GO:2001141 regulation of RNA biosynthetic process 23.1884 6 no
GO:0010243 response to organonitrogen compound 23.1884 4 no
GO:0042981 regulation of apoptotic process 23.1884 5 no
GO:0043067 regulation of programmed cell death 23.1884 4 no
GO:0009967 positive regulation of signal transduction 23.1884 5 no
GO:0010563 negative regulation of phosphorus metabolic process 23.1884 6 no
GO:0031400 negative regulation of protein modification process 23.1884 7 no
GO:0045936 negative regulation of phosphate metabolic process 23.1884 7 no
GO:0033043 regulation of organelle organization 23.1884 5 yes
GO:0006796 phosphate-containing compound metabolic process 21.7391 4 no
GO:0045859 regulation of protein kinase activity 21.7391 6 no
GO:0051726 regulation of cell cycle 21.7391 4 no
GO:1901701 cellular response to oxygen-containing compound 21.7391 4 no
GO:0141124 intracellular signaling cassette 21.7391 4 no
GO:0044057 regulation of system process 21.7391 4 no
GO:0071310 cellular response to organic substance 21.7391 4 no
GO:0051240 positive regulation of multicellular organismal process 21.7391 4 no
GO:0050807 regulation of synapse organization 21.7391 5 no
GO:0010975 regulation of neuron projection development 21.7391 7 yes
GO:2000026 regulation of multicellular organismal development 20.2899 4 yes
GO:0034765 regulation of monoatomic ion transmembrane transport 20.2899 5 no
GO:0043269 regulation of monoatomic ion transport 20.2899 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.2899 6 no
GO:0043085 positive regulation of catalytic activity 20.2899 4 no
GO:0042326 negative regulation of phosphorylation 20.2899 8 no
GO:1902903 regulation of supramolecular fiber organization 18.8406 5 yes
GO:0048812 neuron projection morphogenesis 18.8406 5 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 18.8406 4 yes
GO:0051960 regulation of nervous system development 17.3913 5 yes
GO:0060284 regulation of cell development 17.3913 5 yes
GO:0043254 regulation of protein-containing complex assembly 15.9420 5 yes
GO:0050767 regulation of neurogenesis 15.9420 6 yes
GO:0051093 negative regulation of developmental process 15.9420 4 yes
GO:0051493 regulation of cytoskeleton organization 15.9420 6 yes
GO:0001558 regulation of cell growth 14.4928 4 yes
GO:0032386 regulation of intracellular transport 14.4928 5 yes
GO:0031345 negative regulation of cell projection organization 13.0435 6 yes
GO:0032388 positive regulation of intracellular transport 13.0435 5 yes
GO:0045596 negative regulation of cell differentiation 13.0435 5 yes
GO:0051241 negative regulation of multicellular organismal process 13.0435 4 yes
GO:0010639 negative regulation of organelle organization 11.5942 6 yes
GO:0032271 regulation of protein polymerization 11.5942 6 yes
GO:0043393 regulation of protein binding 11.5942 4 yes
GO:0048638 regulation of developmental growth 11.5942 4 yes
GO:1902904 negative regulation of supramolecular fiber organization 10.1449 6 yes
GO:0031110 regulation of microtubule polymerization or depolymerization 10.1449 6 yes
GO:0031113 regulation of microtubule polymerization 10.1449 6 yes
GO:0032886 regulation of microtubule-based process 10.1449 4 yes
GO:0070507 regulation of microtubule cytoskeleton organization 10.1449 5 yes
GO:0010977 negative regulation of neuron projection development 8.6957 7 yes
GO:0031333 negative regulation of protein-containing complex assembly 8.6957 6 yes
GO:0050770 regulation of axonogenesis 8.6957 5 yes
GO:0051494 negative regulation of cytoskeleton organization 8.6957 7 yes
GO:0010721 negative regulation of cell development 7.2464 6 yes
GO:0048666 neuron development 7.2464 4 yes
GO:0050768 negative regulation of neurogenesis 7.2464 6 yes
GO:0051100 negative regulation of binding 7.2464 4 yes
GO:0051961 negative regulation of nervous system development 7.2464 5 yes
GO:0030516 regulation of axon extension 5.7971 5 yes
GO:0031111 negative regulation of microtubule polymerization or depolymerization 5.7971 7 yes
GO:0031115 negative regulation of microtubule polymerization 5.7971 7 yes
GO:0032272 negative regulation of protein polymerization 5.7971 7 yes
GO:0048813 dendrite morphogenesis 5.7971 6 yes
GO:0050771 negative regulation of axonogenesis 5.7971 6 yes
GO:0061387 regulation of extent of cell growth 5.7971 5 yes
GO:1902803 regulation of synaptic vesicle transport 4.3478 4 yes
GO:0021954 central nervous system neuron development 4.3478 5 yes
GO:0030308 negative regulation of cell growth 4.3478 5 yes
GO:0032091 negative regulation of protein binding 4.3478 5 yes
GO:0045926 negative regulation of growth 4.3478 4 yes
GO:1902805 positive regulation of synaptic vesicle transport 2.8986 5 yes
GO:1903742 regulation of anterograde synaptic vesicle transport 2.8986 5 yes
GO:1903744 positive regulation of anterograde synaptic vesicle transport 2.8986 6 yes
GO:1904526 regulation of microtubule binding 2.8986 5 yes
GO:1904527 negative regulation of microtubule binding 2.8986 6 yes
GO:1904809 regulation of dense core granule transport 2.8986 6 yes
GO:1904811 positive regulation of dense core granule transport 2.8986 6 yes
GO:0030517 negative regulation of axon extension 2.8986 6 yes
GO:0048640 negative regulation of developmental growth 2.8986 5 yes
GO:0060632 regulation of microtubule-based movement 2.8986 5 yes
GO:1901608 regulation of vesicle transport along microtubule 2.8986 7 yes
GO:1901610 positive regulation of vesicle transport along microtubule 2.8986 6 yes
GO:1901951 regulation of anterograde dense core granule transport 2.8986 7 yes
GO:1901953 positive regulation of anterograde dense core granule transport 2.8986 7 yes
GO:1902513 regulation of organelle transport along microtubule 2.8986 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CP110_HUMAN [view interactions] Low throughput no yes
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
KNDC1_HUMAN [view interactions] Low throughput no no
SYN1_HUMAN [view entry] [view interactions] Low throughput yes no
CPEB1_HUMAN [view entry] [view interactions] Low throughput yes no
DGKZ_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
DGKI_HUMAN [view entry] [view interactions] Low throughput yes no
CADM1_HUMAN [view entry] [view interactions] Low throughput yes no
VAC14_HUMAN [view entry] [view interactions] Low throughput yes yes
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
KCC2D_HUMAN [view entry] [view interactions] Low throughput yes yes
RUSC1_HUMAN [view entry] [view interactions] Low throughput yes yes
TBB3_HUMAN [view entry] [view interactions] Low throughput yes yes
MYO7A_HUMAN [view interactions] Low throughput no yes
DAG1_HUMAN [view entry] [view interactions] Low throughput yes no
TBA1A_HUMAN [view entry] [view interactions] Low throughput yes yes
SMO_HUMAN [view entry] [view interactions] Low throughput yes yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
NFL_HUMAN [view entry] [view interactions] Low throughput yes yes
MTAP2_HUMAN [view entry] [view interactions] Low throughput yes yes
PLEC_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTB_HUMAN [view entry] [view interactions] Low throughput yes no
MARK4_HUMAN [view interactions] Low throughput no yes
MARK3_HUMAN [view interactions] Low throughput no yes
MARK1_HUMAN [view entry] [view interactions] Low throughput yes no
RAE1L_HUMAN [view interactions] Low throughput no no
NEUM_HUMAN [view entry] [view interactions] Low throughput yes yes
ITCH_HUMAN [view interactions] High throughput no yes
ADIP_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
NF2L2_HUMAN [view interactions] High throughput no yes
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
DHB12_HUMAN [view entry] [view interactions] High throughput yes yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
LRRK2_HUMAN [view interactions] High throughput no yes
MTR1B_HUMAN [view interactions] High throughput no yes
PSN1_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
PTBP3_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
CP135_HUMAN [view interactions] High throughput no no
JUNB_HUMAN [view interactions] High throughput no yes
PEBB_HUMAN [view interactions] High throughput no no
SCHI1_HUMAN [view interactions] High throughput no yes
MDM2_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
NMDE2_HUMAN [view entry] [view interactions] High throughput yes no
ATX3_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
KTNA1_HUMAN [view interactions] High throughput no yes
HECW2_HUMAN [view entry] [view interactions] High throughput yes no
ARMC1_HUMAN [view interactions] High throughput no yes
HAX1_HUMAN [view interactions] High throughput no no
NUFP1_HUMAN [view interactions] High throughput no yes
DGUOK_HUMAN [view interactions] High throughput no yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
GLUC_HUMAN [view interactions] High throughput no no
FBXW8_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
DX39A_HUMAN [view interactions] High throughput no yes
KAPCG_HUMAN [view interactions] High throughput no no
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3A_HUMAN [view interactions] High throughput no yes
KAP2_HUMAN [view entry] [view interactions] High throughput yes yes
THB_HUMAN [view interactions] High throughput no no
CNTP2_HUMAN [view entry] [view interactions] High throughput yes yes
MYCN_HUMAN [view interactions] High throughput no no
MSX2_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
NED4L_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
DHX9_HUMAN [view interactions] High throughput no yes
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
ROA0_HUMAN [view interactions] High throughput no yes
IF2B3_HUMAN [view interactions] High throughput no no
ABCF1_HUMAN [view interactions] High throughput no yes
DIM1_HUMAN [view interactions] High throughput no yes
EIF3C_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3K_HUMAN [view interactions] High throughput no yes
NMT1_HUMAN [view interactions] High throughput no yes
PA2G4_HUMAN [view interactions] High throughput no yes
YBOX1_HUMAN [view interactions] High throughput no yes
PRS8_HUMAN [view interactions] High throughput no yes
PSD13_HUMAN [view interactions] High throughput no yes
PSMD8_HUMAN [view interactions] High throughput no yes
RL23A_HUMAN [view entry] [view interactions] High throughput yes yes
EIFCL_HUMAN [view interactions] High throughput no yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
STMN3_HUMAN [view interactions] High throughput no yes
VISL1_HUMAN [view entry] [view interactions] High throughput yes no
TTBK1_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
TRI36_HUMAN [view interactions] High throughput no no
AP2S1_HUMAN [view entry] [view interactions] High throughput yes no
BRSK2_HUMAN [view interactions] High throughput no no
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
PPP5_HUMAN [view entry] [view interactions] High throughput yes yes
RHEB_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
SPAST_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
TAOK2_HUMAN [view entry] [view interactions] High throughput yes yes