Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DGKZ_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Does not regulate RASGRP1 activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DGKZ_HUMAN
GO:0000166 nucleotide binding 27.2727 4 yes
GO:0016301 kinase activity 27.2727 4 yes
GO:0017076 purine nucleotide binding 27.2727 5 yes
GO:0032555 purine ribonucleotide binding 27.2727 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.2727 4 yes
GO:0043168 anion binding 27.2727 4 yes
GO:0019900 kinase binding 27.2727 4 no
GO:0005524 ATP binding 24.2424 5 yes
GO:0030554 adenyl nucleotide binding 24.2424 6 yes
GO:0032559 adenyl ribonucleotide binding 24.2424 5 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 21.2121 4 yes
GO:0043169 cation binding 15.1515 4 yes
GO:0046872 metal ion binding 15.1515 5 yes
GO:0001727 lipid kinase activity 6.0606 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DGKZ_HUMAN
GO:0048522 positive regulation of cellular process 66.6667 4 no
GO:0048523 negative regulation of cellular process 63.6364 4 yes
GO:0010646 regulation of cell communication 60.6061 4 yes
GO:0060255 regulation of macromolecule metabolic process 57.5758 4 no
GO:0080090 regulation of primary metabolic process 54.5455 4 no
GO:0009966 regulation of signal transduction 51.5152 4 yes
GO:0051128 regulation of cellular component organization 51.5152 4 no
GO:0031323 regulation of cellular metabolic process 48.4848 4 no
GO:0051246 regulation of protein metabolic process 48.4848 5 no
GO:0051049 regulation of transport 48.4848 4 no
GO:0042127 regulation of cell population proliferation 45.4545 4 no
GO:0009892 negative regulation of metabolic process 39.3939 4 no
GO:0009893 positive regulation of metabolic process 39.3939 4 no
GO:0010604 positive regulation of macromolecule metabolic process 39.3939 5 no
GO:0010605 negative regulation of macromolecule metabolic process 39.3939 5 no
GO:0048584 positive regulation of response to stimulus 39.3939 4 no
GO:0009889 regulation of biosynthetic process 36.3636 4 no
GO:0010556 regulation of macromolecule biosynthetic process 36.3636 5 no
GO:0010647 positive regulation of cell communication 36.3636 5 no
GO:0023056 positive regulation of signaling 36.3636 4 no
GO:0031326 regulation of cellular biosynthetic process 36.3636 5 no
GO:0008104 protein localization 36.3636 4 no
GO:0031399 regulation of protein modification process 36.3636 6 no
GO:0010648 negative regulation of cell communication 33.3333 5 yes
GO:0023057 negative regulation of signaling 33.3333 4 yes
GO:0048585 negative regulation of response to stimulus 33.3333 4 yes
GO:0008284 positive regulation of cell population proliferation 33.3333 5 no
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0010468 regulation of gene expression 33.3333 6 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0001932 regulation of protein phosphorylation 33.3333 7 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:0009968 negative regulation of signal transduction 30.3030 5 yes
GO:0050804 modulation of chemical synaptic transmission 30.3030 5 yes
GO:0099177 regulation of trans-synaptic signaling 30.3030 4 yes
GO:0051247 positive regulation of protein metabolic process 30.3030 6 no
GO:0031325 positive regulation of cellular metabolic process 30.3030 5 no
GO:0022607 cellular component assembly 30.3030 4 no
GO:0045595 regulation of cell differentiation 30.3030 4 no
GO:0051050 positive regulation of transport 30.3030 4 no
GO:0060341 regulation of cellular localization 30.3030 4 no
GO:0006796 phosphate-containing compound metabolic process 27.2727 4 yes
GO:0051726 regulation of cell cycle 27.2727 4 yes
GO:0006915 apoptotic process 27.2727 4 no
GO:0009890 negative regulation of biosynthetic process 27.2727 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0031327 negative regulation of cellular biosynthetic process 27.2727 6 no
GO:0036211 protein modification process 27.2727 4 no
GO:0042981 regulation of apoptotic process 27.2727 5 no
GO:0043067 regulation of programmed cell death 27.2727 4 no
GO:0043412 macromolecule modification 27.2727 4 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0006996 organelle organization 27.2727 4 no
GO:0051130 positive regulation of cellular component organization 27.2727 5 no
GO:0032880 regulation of protein localization 27.2727 5 no
GO:0033043 regulation of organelle organization 27.2727 5 no
GO:0051241 negative regulation of multicellular organismal process 27.2727 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.2727 5 no
GO:0010629 negative regulation of gene expression 24.2424 7 no
GO:0043066 negative regulation of apoptotic process 24.2424 6 no
GO:0043069 negative regulation of programmed cell death 24.2424 5 no
GO:0031401 positive regulation of protein modification process 24.2424 7 no
GO:0099536 synaptic signaling 24.2424 4 no
GO:0030030 cell projection organization 24.2424 4 no
GO:0031344 regulation of cell projection organization 24.2424 5 no
GO:0043933 protein-containing complex organization 24.2424 4 no
GO:0051094 positive regulation of developmental process 24.2424 4 no
GO:0141124 intracellular signaling cassette 24.2424 4 no
GO:0022603 regulation of anatomical structure morphogenesis 24.2424 4 no
GO:0009891 positive regulation of biosynthetic process 24.2424 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 24.2424 6 no
GO:0031328 positive regulation of cellular biosynthetic process 24.2424 6 no
GO:0030334 regulation of cell migration 24.2424 5 no
GO:2000145 regulation of cell motility 24.2424 4 no
GO:0010564 regulation of cell cycle process 21.2121 5 yes
GO:0016310 phosphorylation 21.2121 5 yes
GO:0050776 regulation of immune response 21.2121 4 yes
GO:0001934 positive regulation of protein phosphorylation 21.2121 8 no
GO:0007268 chemical synaptic transmission 21.2121 7 no
GO:0008285 negative regulation of cell population proliferation 21.2121 5 no
GO:0010562 positive regulation of phosphorus metabolic process 21.2121 6 no
GO:0042327 positive regulation of phosphorylation 21.2121 8 no
GO:0043085 positive regulation of catalytic activity 21.2121 4 no
GO:0045937 positive regulation of phosphate metabolic process 21.2121 7 no
GO:0098916 anterograde trans-synaptic signaling 21.2121 6 no
GO:0099537 trans-synaptic signaling 21.2121 5 no
GO:0065003 protein-containing complex assembly 21.2121 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.2121 6 no
GO:0120036 plasma membrane bounded cell projection organization 21.2121 5 no
GO:1903829 positive regulation of protein localization 21.2121 5 no
GO:0043408 regulation of MAPK cascade 21.2121 6 no
GO:2000026 regulation of multicellular organismal development 21.2121 4 no
GO:0044087 regulation of cellular component biogenesis 21.2121 4 no
GO:0051240 positive regulation of multicellular organismal process 21.2121 4 no
GO:0006355 regulation of DNA-templated transcription 21.2121 7 no
GO:0051252 regulation of RNA metabolic process 21.2121 5 no
GO:0071702 organic substance transport 21.2121 4 no
GO:0071705 nitrogen compound transport 21.2121 4 no
GO:0080134 regulation of response to stress 21.2121 4 no
GO:2001141 regulation of RNA biosynthetic process 21.2121 6 no
GO:0002683 negative regulation of immune system process 15.1515 4 yes
GO:0006644 phospholipid metabolic process 12.1212 4 yes
GO:0006650 glycerophospholipid metabolic process 12.1212 5 yes
GO:0006974 DNA damage response 12.1212 4 yes
GO:0007346 regulation of mitotic cell cycle 12.1212 5 yes
GO:0046486 glycerolipid metabolic process 12.1212 4 yes
GO:0008610 lipid biosynthetic process 9.0909 4 yes
GO:0008654 phospholipid biosynthetic process 9.0909 5 yes
GO:0010948 negative regulation of cell cycle process 9.0909 6 yes
GO:0045017 glycerolipid biosynthetic process 9.0909 4 yes
GO:0045786 negative regulation of cell cycle 9.0909 5 yes
GO:0045930 negative regulation of mitotic cell cycle 9.0909 6 yes
GO:0046474 glycerophospholipid biosynthetic process 9.0909 5 yes
GO:0090407 organophosphate biosynthetic process 9.0909 4 yes
GO:1901987 regulation of cell cycle phase transition 9.0909 6 yes
GO:1901988 negative regulation of cell cycle phase transition 9.0909 7 yes
GO:1901990 regulation of mitotic cell cycle phase transition 9.0909 6 yes
GO:1901991 negative regulation of mitotic cell cycle phase transition 9.0909 7 yes
GO:1902806 regulation of cell cycle G1/S phase transition 9.0909 7 yes
GO:1902807 negative regulation of cell cycle G1/S phase transition 9.0909 8 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 9.0909 7 yes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 9.0909 8 yes
GO:0030258 lipid modification 6.0606 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG3_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG2_HUMAN [view entry] [view interactions] Low throughput yes yes
RB_HUMAN [view interactions] Low throughput no yes
SYN1_HUMAN [view entry] [view interactions] Low throughput yes no
MTAP2_HUMAN [view entry] [view interactions] Low throughput yes yes
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
PLCG1_HUMAN [view entry] [view interactions] Low throughput yes yes
DMD_HUMAN [view entry] [view interactions] Low throughput yes no
RASH_HUMAN [view entry] [view interactions] Low throughput yes no
GRP1_HUMAN [view interactions] Low throughput no no
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
PAR6A_HUMAN [view interactions] Low throughput no yes
RBL1_HUMAN [view interactions] Low throughput no yes
RBL2_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
SNX27_HUMAN [view entry] [view interactions] Low throughput yes no
SMO_HUMAN [view entry] [view interactions] Low throughput yes yes
SNTA1_HUMAN [view entry] [view interactions] Low throughput yes no
SNTB1_HUMAN [view entry] [view interactions] Low throughput yes yes
SNTB2_HUMAN [view entry] [view interactions] Low throughput yes no
STING_HUMAN [view interactions] High throughput no yes
MK06_HUMAN [view interactions] High throughput no yes
ARRB1_HUMAN [view entry] [view interactions] High throughput yes yes
ARRB2_HUMAN [view entry] [view interactions] High throughput yes no
MECOM_HUMAN [view interactions] High throughput no yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
MYZAP_HUMAN [view interactions] High throughput no yes
GRL1A_HUMAN [view interactions] High throughput no no
SAT1_HUMAN [view interactions] High throughput no yes
CBX8_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
EPHA1_HUMAN [view interactions] High throughput no yes
SPAG6_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
PTN3_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
RBM28_HUMAN [view interactions] High throughput no yes
NOC2L_HUMAN [view interactions] High throughput no yes
H15_HUMAN [view interactions] High throughput no no
H12_HUMAN [view interactions] High throughput no yes
CEBPZ_HUMAN [view interactions] High throughput no no
ASCC3_HUMAN [view interactions] High throughput no yes
COPT1_HUMAN [view interactions] High throughput no no
EFNB1_HUMAN [view interactions] High throughput no yes
NOL6_HUMAN [view interactions] High throughput no no
HNRLL_HUMAN [view interactions] High throughput no yes
NOL8_HUMAN [view interactions] High throughput no yes
FNTB_HUMAN [view interactions] High throughput no no
DDX27_HUMAN [view interactions] High throughput no no
HM20A_HUMAN [view interactions] High throughput no yes
TEBP_HUMAN [view interactions] High throughput no yes
LRC15_HUMAN [view interactions] High throughput no no
RL36L_HUMAN [view interactions] High throughput no no
H2A1_HUMAN [view interactions] High throughput no yes
ZN629_HUMAN [view interactions] High throughput no no
FNBP4_HUMAN [view interactions] High throughput no yes
WDR36_HUMAN [view interactions] High throughput no no
FNTA_HUMAN [view interactions] High throughput no yes
COX10_HUMAN [view interactions] High throughput no yes
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
RRP8_HUMAN [view interactions] High throughput no yes
ZKSC8_HUMAN [view interactions] High throughput no yes
ARK2N_HUMAN [view interactions] High throughput no yes
NOC3L_HUMAN [view interactions] High throughput no no
ZC3H1_HUMAN [view interactions] High throughput no yes
FRIL_HUMAN [view interactions] High throughput no yes
DDX51_HUMAN [view interactions] High throughput no no
BMS1_HUMAN [view interactions] High throughput no yes
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
NPA1P_HUMAN [view interactions] High throughput no yes
PI51A_HUMAN [view interactions] High throughput no yes
TRM1L_HUMAN [view interactions] High throughput no yes
TEFM_HUMAN [view interactions] High throughput no no
ECT2L_HUMAN [view interactions] High throughput no no
ASCC2_HUMAN [view interactions] High throughput no yes
FEZF1_HUMAN [view interactions] High throughput no yes
RRP5_HUMAN [view interactions] High throughput no yes
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
KBTB7_HUMAN [view interactions] High throughput no yes
KBTB6_HUMAN [view interactions] High throughput no yes
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2O_HUMAN [view interactions] High throughput no yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
GBA1_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
SPPL3_HUMAN [view interactions] High throughput no no
JIP4_HUMAN [view interactions] High throughput no yes
OGA_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] High throughput yes no
HMGN5_HUMAN [view interactions] High throughput no no
KI20B_HUMAN [view entry] [view interactions] High throughput yes yes