SNTB1_HUMAN
Evidence for PS localization
Functions
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNTB1_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 40.0000 | 4 | no |
| GO:0003779 | actin binding | 26.6667 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 23.3333 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 23.3333 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.3333 | 4 | no |
| GO:0030165 | PDZ domain binding | 13.3333 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNTB1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 43.3333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 43.3333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.3333 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.0000 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 40.0000 | 4 | no |
| GO:0051049 | regulation of transport | 40.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 36.6667 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 36.6667 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0006936 | muscle contraction | 30.0000 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 30.0000 | 6 | no |
| GO:0051094 | positive regulation of developmental process | 30.0000 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 30.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.6667 | 4 | no |
| GO:0006996 | organelle organization | 26.6667 | 4 | no |
| GO:0007010 | cytoskeleton organization | 26.6667 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.6667 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.6667 | 6 | no |
| GO:0030030 | cell projection organization | 26.6667 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.6667 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 26.6667 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.6667 | 5 | no |
| GO:0010468 | regulation of gene expression | 26.6667 | 5 | no |
| GO:0043269 | regulation of ion transport | 26.6667 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.3333 | 7 | no |
| GO:0030334 | regulation of cell migration | 23.3333 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 23.3333 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.3333 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.3333 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 23.3333 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 23.3333 | 4 | no |
| GO:2000145 | regulation of cell motility | 23.3333 | 4 | no |
| GO:0010959 | regulation of metal ion transport | 23.3333 | 6 | no |
| GO:0034762 | regulation of transmembrane transport | 23.3333 | 4 | no |
| GO:0034765 | regulation of ion transmembrane transport | 23.3333 | 5 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SNTB1_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 13.3333 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 13.3333 | 5 | no |
| DOID:114 | heart disease | 13.3333 | 3 | no |
| DOID:0080000 | muscular disease | 10.0000 | 3 | no |
| DOID:423 | myopathy | 10.0000 | 5 | no |
| DOID:66 | muscle tissue disease | 10.0000 | 4 | no |
| DOID:9884 | muscular dystrophy | 10.0000 | 6 | no |
| DOID:0110274 | autosomal recessive limb-girdle muscular dystrophy | 6.6667 | 8 | no |
| DOID:11724 | limb-girdle muscular dystrophy | 6.6667 | 7 | no |
| DOID:12930 | dilated cardiomyopathy | 6.6667 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ABCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| DMD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADA1D_HUMAN | [view interactions] | Low throughput | no | no |
| DTNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UTRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCN7A_HUMAN | [view interactions] | Low throughput | no | no |
| SCN5A_HUMAN | [view interactions] | Low throughput | no | no |
| NOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DGKZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MORC3_HUMAN | [view interactions] | High throughput | no | yes |
| HM20A_HUMAN | [view interactions] | High throughput | no | yes |
| NAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TENS3_HUMAN | [view interactions] | High throughput | no | no |
| TENS1_HUMAN | [view interactions] | High throughput | no | no |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| SNTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNTB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNL1_HUMAN | [view interactions] | High throughput | no | no |
| ZGPAT_HUMAN | [view interactions] | High throughput | no | no |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPZ1_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCYA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK12_HUMAN | [view interactions] | High throughput | no | no |
| FRPD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLTR2_HUMAN | [view interactions] | High throughput | no | no |
| ASND1_HUMAN | [view interactions] | High throughput | no | yes |
| KCJ12_HUMAN | [view interactions] | High throughput | no | no |
| SIR3_HUMAN | [view interactions] | High throughput | no | yes |
| TNS2_HUMAN | [view interactions] | High throughput | no | no |
| SNTG2_HUMAN | [view interactions] | High throughput | no | no |
| NDEL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA2_HUMAN | [view interactions] | High throughput | no | no |
| SNTG1_HUMAN | [view interactions] | High throughput | no | no |
| SGF29_HUMAN | [view interactions] | High throughput | no | yes |
| TAGAP_HUMAN | [view interactions] | High throughput | no | yes |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| AGRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH3_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DAG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SGCG_HUMAN | [view interactions] | Computational | no | no |
| SGCD_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SSPN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SGCA_HUMAN | [view interactions] | Computational | no | yes |