Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

AGRB1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Inhibits angiogenesis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in AGRB1_HUMAN
GO:0019900 kinase binding 37.5000 4 no
GO:0019901 protein kinase binding 29.1667 5 no
GO:0030165 PDZ domain binding 25.0000 4 yes
GO:0099106 ion channel regulator activity 20.8333 4 no
GO:0004930 G protein-coupled receptor activity 12.5000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in AGRB1_HUMAN
GO:0048522 positive regulation of cellular process 66.6667 4 yes
GO:0010646 regulation of cell communication 58.3333 4 yes
GO:0048523 negative regulation of cellular process 54.1667 4 yes
GO:0051128 regulation of cellular component organization 54.1667 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 yes
GO:0080090 regulation of primary metabolic process 50.0000 4 yes
GO:0051246 regulation of protein metabolic process 45.8333 5 yes
GO:0009966 regulation of signal transduction 45.8333 4 no
GO:0031323 regulation of cellular metabolic process 45.8333 4 yes
GO:0031399 regulation of protein modification process 45.8333 6 yes
GO:0008104 protein localization 41.6667 4 no
GO:0009893 positive regulation of metabolic process 41.6667 4 yes
GO:0031325 positive regulation of cellular metabolic process 41.6667 5 yes
GO:0051049 regulation of transport 37.5000 4 no
GO:0141124 intracellular signaling cassette 37.5000 4 no
GO:1902531 regulation of intracellular signal transduction 37.5000 5 no
GO:0009892 negative regulation of metabolic process 37.5000 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 37.5000 5 yes
GO:0051130 positive regulation of cellular component organization 37.5000 5 yes
GO:0051248 negative regulation of protein metabolic process 33.3333 6 yes
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0044057 regulation of system process 33.3333 4 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 yes
GO:0031400 negative regulation of protein modification process 33.3333 7 yes
GO:0099177 regulation of trans-synaptic signaling 29.1667 4 yes
GO:2000026 regulation of multicellular organismal development 29.1667 4 yes
GO:0001932 regulation of protein phosphorylation 29.1667 7 no
GO:0010562 positive regulation of phosphorus metabolic process 29.1667 6 no
GO:0031401 positive regulation of protein modification process 29.1667 7 no
GO:0034762 regulation of transmembrane transport 29.1667 4 no
GO:0042325 regulation of phosphorylation 29.1667 7 no
GO:0043085 positive regulation of catalytic activity 29.1667 4 no
GO:0045937 positive regulation of phosphate metabolic process 29.1667 7 no
GO:0051050 positive regulation of transport 29.1667 4 no
GO:0051247 positive regulation of protein metabolic process 29.1667 6 no
GO:0009967 positive regulation of signal transduction 29.1667 5 no
GO:0010647 positive regulation of cell communication 29.1667 5 no
GO:0023056 positive regulation of signaling 29.1667 4 no
GO:0031344 regulation of cell projection organization 29.1667 5 no
GO:0048584 positive regulation of response to stimulus 29.1667 4 no
GO:0030030 cell projection organization 29.1667 4 yes
GO:0050804 modulation of chemical synaptic transmission 29.1667 5 yes
GO:0051241 negative regulation of multicellular organismal process 29.1667 4 yes
GO:0051960 regulation of nervous system development 25.0000 5 yes
GO:0061024 membrane organization 25.0000 4 yes
GO:0098657 import into cell 25.0000 4 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 25.0000 4 yes
GO:0001934 positive regulation of protein phosphorylation 25.0000 8 no
GO:0008016 regulation of heart contraction 25.0000 6 no
GO:0010959 regulation of metal ion transport 25.0000 6 no
GO:0022898 regulation of transmembrane transporter activity 25.0000 4 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 25.0000 5 no
GO:0034765 regulation of monoatomic ion transmembrane transport 25.0000 5 no
GO:0042327 positive regulation of phosphorylation 25.0000 8 no
GO:0043269 regulation of monoatomic ion transport 25.0000 5 no
GO:1903522 regulation of blood circulation 25.0000 5 no
GO:1904062 regulation of monoatomic cation transmembrane transport 25.0000 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:0072657 protein localization to membrane 25.0000 4 no
GO:0008285 negative regulation of cell population proliferation 25.0000 5 yes
GO:0009889 regulation of biosynthetic process 25.0000 4 yes
GO:0042127 regulation of cell population proliferation 25.0000 4 yes
GO:0048812 neuron projection morphogenesis 25.0000 5 yes
GO:0051094 positive regulation of developmental process 25.0000 4 yes
GO:2000145 regulation of cell motility 20.8333 4 yes
GO:0001933 negative regulation of protein phosphorylation 20.8333 8 no
GO:0010038 response to metal ion 20.8333 4 no
GO:0010563 negative regulation of phosphorus metabolic process 20.8333 6 no
GO:0010564 regulation of cell cycle process 20.8333 5 no
GO:0033674 positive regulation of kinase activity 20.8333 6 no
GO:0042326 negative regulation of phosphorylation 20.8333 8 no
GO:0043549 regulation of kinase activity 20.8333 5 no
GO:0045859 regulation of protein kinase activity 20.8333 6 no
GO:0045860 positive regulation of protein kinase activity 20.8333 7 no
GO:0045936 negative regulation of phosphate metabolic process 20.8333 7 no
GO:0051051 negative regulation of transport 20.8333 4 no
GO:0051336 regulation of hydrolase activity 20.8333 4 no
GO:0051338 regulation of transferase activity 20.8333 4 no
GO:0051345 positive regulation of hydrolase activity 20.8333 5 no
GO:0051347 positive regulation of transferase activity 20.8333 5 no
GO:0051726 regulation of cell cycle 20.8333 4 no
GO:2001257 regulation of cation channel activity 20.8333 6 no
GO:0010975 regulation of neuron projection development 20.8333 7 no
GO:0022607 cellular component assembly 20.8333 4 no
GO:0035418 protein localization to synapse 20.8333 6 no
GO:0045595 regulation of cell differentiation 20.8333 4 no
GO:1902414 protein localization to cell junction 20.8333 5 no
GO:1990778 protein localization to cell periphery 20.8333 5 no
GO:0048585 negative regulation of response to stimulus 20.8333 4 no
GO:0007409 axonogenesis 20.8333 6 yes
GO:0009891 positive regulation of biosynthetic process 20.8333 5 yes
GO:0030334 regulation of cell migration 20.8333 5 yes
GO:0050807 regulation of synapse organization 20.8333 5 yes
GO:0051240 positive regulation of multicellular organismal process 20.8333 4 yes
GO:0051962 positive regulation of nervous system development 16.6667 5 yes
GO:0099024 plasma membrane invagination 16.6667 6 yes
GO:2000146 negative regulation of cell motility 16.6667 5 yes
GO:0006911 phagocytosis, engulfment 16.6667 7 yes
GO:0010324 membrane invagination 16.6667 5 yes
GO:0030336 negative regulation of cell migration 16.6667 6 yes
GO:0040013 negative regulation of locomotion 16.6667 4 yes
GO:0044087 regulation of cellular component biogenesis 16.6667 4 yes
GO:0044089 positive regulation of cellular component biogenesis 16.6667 5 yes
GO:0051093 negative regulation of developmental process 16.6667 4 yes
GO:1901342 regulation of vasculature development 12.5000 5 yes
GO:1901873 regulation of post-translational protein modification 12.5000 7 yes
GO:1901874 negative regulation of post-translational protein modification 12.5000 8 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 12.5000 8 yes
GO:1903321 negative regulation of protein modification by small protein conjugation or removal 12.5000 9 yes
GO:0006909 phagocytosis 12.5000 4 yes
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 12.5000 4 yes
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 12.5000 5 yes
GO:0010632 regulation of epithelial cell migration 12.5000 4 yes
GO:0031396 regulation of protein ubiquitination 12.5000 9 yes
GO:0031397 negative regulation of protein ubiquitination 12.5000 10 yes
GO:0045765 regulation of angiogenesis 12.5000 5 yes
GO:0051963 regulation of synapse assembly 8.3333 6 yes
GO:0051965 positive regulation of synapse assembly 8.3333 6 yes
GO:0060142 regulation of syncytium formation by plasma membrane fusion 8.3333 4 yes
GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 8.3333 5 yes
GO:0140546 defense response to symbiont 8.3333 4 yes
GO:1901343 negative regulation of vasculature development 8.3333 5 yes
GO:1901739 regulation of myoblast fusion 8.3333 5 yes
GO:1901741 positive regulation of myoblast fusion 8.3333 6 yes
GO:1901888 regulation of cell junction assembly 8.3333 5 yes
GO:1901890 positive regulation of cell junction assembly 8.3333 6 yes
GO:1903426 regulation of reactive oxygen species biosynthetic process 8.3333 5 yes
GO:1903428 positive regulation of reactive oxygen species biosynthetic process 8.3333 6 yes
GO:2000181 negative regulation of blood vessel morphogenesis 8.3333 5 yes
GO:2000377 regulation of reactive oxygen species metabolic process 8.3333 5 yes
GO:2000379 positive regulation of reactive oxygen species metabolic process 8.3333 6 yes
GO:0007422 peripheral nervous system development 8.3333 4 yes
GO:0007517 muscle organ development 8.3333 4 yes
GO:0009894 regulation of catabolic process 8.3333 4 yes
GO:0009895 negative regulation of catabolic process 8.3333 5 yes
GO:0010594 regulation of endothelial cell migration 8.3333 5 yes
GO:0010596 negative regulation of endothelial cell migration 8.3333 6 yes
GO:0010633 negative regulation of epithelial cell migration 8.3333 5 yes
GO:0016525 negative regulation of angiogenesis 8.3333 6 yes
GO:0042176 regulation of protein catabolic process 8.3333 5 yes
GO:0042177 negative regulation of protein catabolic process 8.3333 6 yes
GO:0042742 defense response to bacterium 8.3333 4 yes
GO:0043277 apoptotic cell clearance 8.3333 5 yes
GO:0043652 engulfment of apoptotic cell 8.3333 8 yes
GO:0050829 defense response to Gram-negative bacterium 8.3333 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MAGI3_HUMAN [view interactions] Low throughput no no
BAIP3_HUMAN [view interactions] Low throughput no yes
ELMO1_HUMAN [view entry] [view interactions] Low throughput yes no
DOCK1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
MAGI1_HUMAN [view interactions] Low throughput no no
BAIP2_HUMAN [view entry] [view interactions] Low throughput yes yes
PHYIP_HUMAN [view entry] [view interactions] Low throughput yes yes
AGRB1_HUMAN [view entry] [view interactions] Low throughput yes no
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
MAGI2_HUMAN [view entry] [view interactions] Low throughput yes yes
ELMO2_HUMAN [view entry] [view interactions] Low throughput yes no
RTN4R_HUMAN [view entry] [view interactions] Low throughput yes no
EIF3H_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
DRD2_HUMAN [view entry] [view interactions] High throughput yes no
GPR35_HUMAN [view interactions] High throughput no no
GPR37_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
RN123_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
RAB9A_HUMAN [view interactions] High throughput no yes
RAB3B_HUMAN [view interactions] High throughput no no
TPC10_HUMAN [view interactions] High throughput no no
AB17B_HUMAN [view entry] [view interactions] High throughput yes no
COT2_HUMAN [view interactions] High throughput no no
INADL_HUMAN [view interactions] High throughput no no
DLG1_HUMAN [view entry] [view interactions] High throughput yes yes
LIN7A_HUMAN [view entry] [view interactions] High throughput yes yes
LRRC7_HUMAN [view entry] [view interactions] High throughput yes no
SNTA1_HUMAN [view entry] [view interactions] High throughput yes no
SNTB1_HUMAN [view entry] [view interactions] High throughput yes yes
SNTB2_HUMAN [view entry] [view interactions] High throughput yes no
SNTG2_HUMAN [view interactions] High throughput no no
PDZD2_HUMAN [view interactions] High throughput no yes
AGRB2_HUMAN [view interactions] High throughput no no
LRC4C_HUMAN [view entry] [view interactions] High throughput yes yes
MUC18_HUMAN [view interactions] High throughput no yes