Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PHYIP_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Its interaction with PHYH suggests a role in the development of the central system. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PHYIP_HUMAN
GO:0019900 kinase binding 35.7143 4 yes
GO:0019901 protein kinase binding 28.5714 5 yes
GO:0019902 phosphatase binding 21.4286 4 no
GO:0003677 DNA binding 21.4286 4 no
GO:0003723 RNA binding 21.4286 4 no
GO:0003779 actin binding 21.4286 4 no
GO:1990782 protein tyrosine kinase binding 14.2857 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PHYIP_HUMAN
GO:0048522 positive regulation of cellular process 57.1429 4 no
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0051171 regulation of nitrogen compound metabolic process 50.0000 4 no
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0051246 regulation of protein metabolic process 35.7143 5 no
GO:0099177 regulation of trans-synaptic signaling 35.7143 4 no
GO:0008104 protein localization 35.7143 4 yes
GO:0009966 regulation of signal transduction 35.7143 4 no
GO:0050804 modulation of chemical synaptic transmission 35.7143 5 no
GO:0051130 positive regulation of cellular component organization 35.7143 5 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010038 response to metal ion 28.5714 4 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0022607 cellular component assembly 28.5714 4 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0050890 cognition 28.5714 4 no
GO:0051049 regulation of transport 28.5714 4 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:0051338 regulation of transferase activity 21.4286 4 no
GO:0060341 regulation of cellular localization 21.4286 4 no
GO:0120036 plasma membrane bounded cell projection organization 21.4286 5 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 21.4286 6 no
GO:0009891 positive regulation of biosynthetic process 21.4286 5 no
GO:0009892 negative regulation of metabolic process 21.4286 4 no
GO:0010468 regulation of gene expression 21.4286 5 no
GO:0010556 regulation of macromolecule biosynthetic process 21.4286 5 no
GO:0010605 negative regulation of macromolecule metabolic process 21.4286 5 no
GO:0016070 RNA metabolic process 21.4286 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.4286 5 no
GO:0031326 regulation of cellular biosynthetic process 21.4286 5 no
GO:0051052 regulation of DNA metabolic process 21.4286 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 21.4286 5 no
GO:0090304 nucleic acid metabolic process 21.4286 4 no
GO:0036211 protein modification process 21.4286 4 no
GO:0043412 macromolecule modification 21.4286 4 no
GO:0051093 negative regulation of developmental process 21.4286 4 no
GO:0051240 positive regulation of multicellular organismal process 21.4286 4 no
GO:0051960 regulation of nervous system development 21.4286 5 no
GO:0051962 positive regulation of nervous system development 21.4286 5 no
GO:2000026 regulation of multicellular organismal development 21.4286 4 no
GO:0045595 regulation of cell differentiation 21.4286 4 no
GO:0070848 response to growth factor 21.4286 4 no
GO:0071310 cellular response to organic substance 21.4286 4 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0006996 organelle organization 21.4286 4 no
GO:0007612 learning 21.4286 4 no
GO:0009967 positive regulation of signal transduction 21.4286 5 no
GO:0010604 positive regulation of macromolecule metabolic process 21.4286 5 no
GO:0022603 regulation of anatomical structure morphogenesis 21.4286 4 no
GO:0031175 neuron projection development 21.4286 6 no
GO:0032990 cell part morphogenesis 21.4286 4 no
GO:0034762 regulation of transmembrane transport 21.4286 4 no
GO:0034765 regulation of ion transmembrane transport 21.4286 5 no
GO:0043269 regulation of ion transport 21.4286 5 no
GO:0043933 protein-containing complex organization 21.4286 4 no
GO:0044057 regulation of system process 21.4286 4 no
GO:0048812 neuron projection morphogenesis 21.4286 7 no
GO:0048858 cell projection morphogenesis 21.4286 5 no
GO:0050806 positive regulation of synaptic transmission 21.4286 5 no
GO:0051129 negative regulation of cellular component organization 21.4286 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 21.4286 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
AGRB1_HUMAN [view entry] [view interactions] Low throughput yes no
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
CAH10_HUMAN [view interactions] High throughput no yes
PTH2_HUMAN [view interactions] High throughput no yes
LIMD1_HUMAN [view interactions] High throughput no yes
KIF15_HUMAN [view interactions] High throughput no no
KPCD2_HUMAN [view interactions] High throughput no yes
TRIP6_HUMAN [view interactions] High throughput no yes
PAQR5_HUMAN [view interactions] High throughput no no
T255B_HUMAN [view interactions] High throughput no no
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
ERG28_HUMAN [view interactions] High throughput no yes
CSN6_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
MED8_HUMAN [view interactions] High throughput no yes
NDRG1_HUMAN [view entry] [view interactions] High throughput yes yes
TTHY_HUMAN [view interactions] High throughput no no
PLPL2_HUMAN [view interactions] High throughput no no
SPT5H_HUMAN [view interactions] High throughput no yes
HDA11_HUMAN [view interactions] High throughput no no
WDR89_HUMAN [view entry] [view interactions] High throughput yes yes
MAGD4_HUMAN [view interactions] High throughput no no
F131A_HUMAN [view interactions] High throughput no yes
MET18_HUMAN [view interactions] High throughput no yes
NDUV3_HUMAN [view interactions] High throughput no yes
PPIE_HUMAN [view interactions] High throughput no yes
S10AD_HUMAN [view interactions] High throughput no yes
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
SMRC2_HUMAN [view interactions] High throughput no yes
ZZEF1_HUMAN [view interactions] High throughput no no
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
NFE2_HUMAN [view interactions] High throughput no no
PHYIP_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
ANR12_HUMAN [view interactions] High throughput no yes
OXDA_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
TIA1_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
MSI2H_HUMAN [view interactions] High throughput no yes
PARL_HUMAN [view interactions] High throughput no yes
COG7_HUMAN [view interactions] High throughput no yes
TBB8_HUMAN [view interactions] High throughput no no
TBB1_HUMAN [view interactions] High throughput no yes
MARH7_HUMAN [view interactions] High throughput no yes
ANR40_HUMAN [view interactions] High throughput no yes
PHIPL_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
PAHX_HUMAN [view interactions] High throughput no yes