TANC1_HUMAN
Evidence for PS localization
Functions
May be a scaffold component in the postsynaptic density. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TANC1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 38.1818 | 4 | no |
| GO:0019900 | kinase binding | 38.1818 | 4 | no |
| GO:0000166 | nucleotide binding | 34.5455 | 4 | no |
| GO:0017076 | purine nucleotide binding | 34.5455 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 34.5455 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.5455 | 4 | no |
| GO:0019901 | protein kinase binding | 30.9091 | 5 | no |
| GO:0045296 | cadherin binding | 25.4545 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TANC1_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 61.8182 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 58.1818 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 58.1818 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 58.1818 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 56.3636 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 56.3636 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.7273 | 4 | no |
| GO:0008104 | protein localization | 50.9091 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 45.4545 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.4545 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 45.4545 | 5 | no |
| GO:0009966 | regulation of signal transduction | 43.6364 | 4 | no |
| GO:0010468 | regulation of gene expression | 43.6364 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 41.8182 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 40.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0051049 | regulation of transport | 38.1818 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 34.5455 | 5 | no |
| GO:0031399 | regulation of protein modification process | 34.5455 | 6 | no |
| GO:0022607 | cellular component assembly | 34.5455 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 32.7273 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.7273 | 5 | no |
| GO:0023056 | positive regulation of signaling | 32.7273 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 30.9091 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 30.9091 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.9091 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 30.9091 | 5 | no |
| GO:0030030 | cell projection organization | 29.0909 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 29.0909 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 29.0909 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.0909 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.0909 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.0909 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 27.2727 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 27.2727 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 27.2727 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 27.2727 | 6 | no |
| GO:0007010 | cytoskeleton organization | 27.2727 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.2727 | 7 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.2727 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 27.2727 | 6 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 27.2727 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 27.2727 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 25.4545 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 25.4545 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.4545 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.6364 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 23.6364 | 7 | no |
| GO:0071310 | cellular response to organic substance | 23.6364 | 4 | no |
| GO:0071702 | organic substance transport | 23.6364 | 4 | no |
| GO:0071705 | nitrogen compound transport | 23.6364 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.6364 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.6364 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.6364 | 6 | no |
| GO:0033043 | regulation of organelle organization | 23.6364 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 21.8182 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.8182 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 21.8182 | 7 | no |
| GO:0042127 | regulation of cell population proliferation | 21.8182 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 21.8182 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 21.8182 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 21.8182 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 21.8182 | 5 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 21.8182 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.8182 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.8182 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.8182 | 6 | no |
| GO:0060341 | regulation of cellular localization | 21.8182 | 4 | no |
| GO:0050807 | regulation of synapse organization | 12.7273 | 5 | yes |
| GO:0050890 | cognition | 10.9091 | 4 | yes |
| GO:0099175 | regulation of postsynapse organization | 9.0909 | 6 | yes |
| GO:0007612 | learning | 5.4545 | 4 | yes |
| GO:0106027 | neuron projection organization | 5.4545 | 6 | yes |
| GO:0008306 | associative learning | 3.6364 | 5 | yes |
| GO:0008542 | visual learning | 3.6364 | 4 | yes |
| GO:0009416 | response to light stimulus | 3.6364 | 4 | yes |
| GO:0097061 | dendritic spine organization | 3.6364 | 5 | yes |
| GO:0099173 | postsynapse organization | 3.6364 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DLG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HOME1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AINX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INADL_HUMAN | [view interactions] | High throughput | no | no |
| SNTB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| ZMYD8_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TEBP_HUMAN | [view interactions] | High throughput | no | yes |
| TX1B3_HUMAN | [view interactions] | High throughput | no | no |
| TRI52_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| AGAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| TANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRK_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |