PRIC2_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRIC2_HUMAN |
|---|---|---|---|---|
| GO:0030695 | GTPase regulator activity | 35.0000 | 4 | no |
| GO:0043169 | cation binding | 32.5000 | 4 | yes |
| GO:0046872 | metal ion binding | 32.5000 | 5 | yes |
| GO:0031267 | small GTPase binding | 25.0000 | 5 | no |
| GO:0051020 | GTPase binding | 25.0000 | 4 | no |
| GO:0046914 | transition metal ion binding | 17.5000 | 6 | yes |
| GO:0008270 | zinc ion binding | 15.0000 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRIC2_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 60.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 55.0000 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 55.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 52.5000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 42.5000 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 42.5000 | 4 | no |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 37.5000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 37.5000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 37.5000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 37.5000 | 5 | no |
| GO:0006996 | organelle organization | 37.5000 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.0000 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 35.0000 | 5 | no |
| GO:0030030 | cell projection organization | 35.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.0000 | 5 | no |
| GO:0008104 | protein localization | 35.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 32.5000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 32.5000 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 32.5000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.0000 | 5 | no |
| GO:0031399 | regulation of protein modification process | 30.0000 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.0000 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 30.0000 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 30.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.5000 | 7 | no |
| GO:0009892 | negative regulation of metabolic process | 27.5000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.5000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.5000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.5000 | 6 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 27.5000 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 27.5000 | 5 | no |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 27.5000 | 6 | no |
| GO:0051049 | regulation of transport | 27.5000 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 25.0000 | 8 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 25.0000 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.0000 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.0000 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.0000 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 22.5000 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 22.5000 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.5000 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.5000 | 7 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.5000 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 22.5000 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.5000 | 5 | no |
| GO:0016055 | Wnt signaling pathway | 10.0000 | 4 | yes |
| GO:0035567 | non-canonical Wnt signaling pathway | 10.0000 | 5 | yes |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 10.0000 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VANG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PARP2_HUMAN | [view interactions] | High throughput | no | yes |
| TANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| RHG15_HUMAN | [view interactions] | High throughput | no | no |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAL_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| KLHL7_HUMAN | [view interactions] | High throughput | no | yes |
| LPXN_HUMAN | [view interactions] | High throughput | no | yes |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG40_HUMAN | [view interactions] | High throughput | no | no |
| RHG42_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIO_HUMAN | [view interactions] | High throughput | no | yes |
| DAB2P_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| GLI2_HUMAN | [view interactions] | High throughput | no | yes |
| LHX3_HUMAN | [view interactions] | High throughput | no | no |
| LMA2L_HUMAN | [view interactions] | High throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE6B_HUMAN | [view interactions] | High throughput | no | no |
| PIAS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPOPL_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| TIM44_HUMAN | [view interactions] | High throughput | no | yes |
| CEGT_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| RPGF4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGF1B_HUMAN | [view interactions] | High throughput | no | no |
| SRGP1_HUMAN | [view interactions] | High throughput | no | no |
| SRGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STA13_HUMAN | [view interactions] | High throughput | no | yes |
| STRP2_HUMAN | [view interactions] | High throughput | no | yes |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF2_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |