NP1L4_HUMAN
Evidence for PS localization
Functions
Acts as histone chaperone in nucleosome assembly. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NP1L4_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 44.8276 | 4 | yes |
| GO:0043168 | anion binding | 24.1379 | 4 | no |
| GO:0000166 | nucleotide binding | 22.4138 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.4138 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.4138 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.6897 | 4 | no |
| GO:0045296 | cadherin binding | 20.6897 | 4 | no |
| GO:0031491 | nucleosome binding | 3.4483 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NP1L4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 51.7241 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.8276 | 4 | no |
| GO:0022607 | cellular component assembly | 44.8276 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 41.3793 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 41.3793 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 41.3793 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 41.3793 | 4 | no |
| GO:0006996 | organelle organization | 41.3793 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 36.2069 | 5 | no |
| GO:0043933 | protein-containing complex organization | 36.2069 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 34.4828 | 4 | no |
| GO:0010646 | regulation of cell communication | 34.4828 | 4 | no |
| GO:0008104 | protein localization | 34.4828 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 32.7586 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.7586 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.7586 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.7586 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.7586 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 32.7586 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 31.0345 | 4 | no |
| GO:0010468 | regulation of gene expression | 31.0345 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 31.0345 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.3103 | 5 | no |
| GO:0071702 | organic substance transport | 29.3103 | 4 | no |
| GO:0043412 | macromolecule modification | 27.5862 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.5862 | 5 | no |
| GO:0071705 | nitrogen compound transport | 27.5862 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.5862 | 4 | no |
| GO:0009894 | regulation of catabolic process | 25.8621 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 25.8621 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.8621 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.8621 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.8621 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.8621 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 25.8621 | 6 | no |
| GO:0036211 | protein modification process | 25.8621 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 24.1379 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.1379 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.1379 | 6 | no |
| GO:0031399 | regulation of protein modification process | 24.1379 | 6 | no |
| GO:0033043 | regulation of organelle organization | 24.1379 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.4138 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.4138 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 22.4138 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.4138 | 4 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.4138 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 22.4138 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.4138 | 4 | no |
| GO:0051726 | regulation of cell cycle | 22.4138 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.4138 | 6 | no |
| GO:0015031 | protein transport | 22.4138 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.4138 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.4138 | 5 | no |
| GO:0060341 | regulation of cellular localization | 22.4138 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.4138 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.4138 | 5 | no |
| GO:0090304 | nucleic acid metabolic process | 20.6897 | 4 | no |
| GO:0031400 | negative regulation of protein modification process | 20.6897 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 20.6897 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 20.6897 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 20.6897 | 6 | no |
| GO:0006325 | chromatin organization | 8.6207 | 6 | yes |
| GO:0071824 | protein-DNA complex organization | 8.6207 | 5 | yes |
| GO:0006334 | nucleosome assembly | 6.8966 | 7 | yes |
| GO:0006338 | chromatin remodeling | 6.8966 | 7 | yes |
| GO:0034728 | nucleosome organization | 6.8966 | 8 | yes |
| GO:0065004 | protein-DNA complex assembly | 6.8966 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| H32_HUMAN | [view interactions] | Low throughput | no | yes |
| H4_HUMAN | [view interactions] | Low throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | Low throughput | no | yes |
| H2B2E_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | Low throughput | no | yes |
| H11_HUMAN | [view interactions] | Low throughput | no | no |
| H31T_HUMAN | [view interactions] | Low throughput | no | yes |
| NP1L4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| H2A2C_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGD2_HUMAN | [view interactions] | Low throughput | no | yes |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| NP1L2_HUMAN | [view interactions] | Low throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| FGF11_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| TR10A_HUMAN | [view interactions] | High throughput | no | no |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| PTN4_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RM39_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| H2B1J_HUMAN | [view interactions] | High throughput | no | yes |
| UTP25_HUMAN | [view interactions] | High throughput | no | yes |
| HM20A_HUMAN | [view interactions] | High throughput | no | yes |
| PHF14_HUMAN | [view interactions] | High throughput | no | yes |
| RM43_HUMAN | [view interactions] | High throughput | no | no |
| TSYL4_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| DGKZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2B3B_HUMAN | [view interactions] | High throughput | no | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARL3_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H10_HUMAN | [view interactions] | High throughput | no | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO9B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| KAT6A_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| PESC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYK_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| APC1_HUMAN | [view interactions] | High throughput | no | no |
| APC10_HUMAN | [view interactions] | High throughput | no | yes |
| APC7_HUMAN | [view interactions] | High throughput | no | yes |
| CDC16_HUMAN | [view interactions] | High throughput | no | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| TAF3_HUMAN | [view interactions] | High throughput | no | no |
| TAF4_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| NOP14_HUMAN | [view interactions] | High throughput | no | yes |
| FKB15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| PTCD3_HUMAN | [view interactions] | High throughput | no | yes |
| LTV1_HUMAN | [view interactions] | High throughput | no | yes |
| CFDP1_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F120A_HUMAN | [view interactions] | High throughput | no | yes |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| CTIF_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB7_HUMAN | [view interactions] | High throughput | no | no |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCNT_HUMAN | [view interactions] | High throughput | no | yes |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN330_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| CCD71_HUMAN | [view interactions] | High throughput | no | no |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| KBTB4_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| JAK3_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP78_HUMAN | [view interactions] | High throughput | no | yes |
| ASPM_HUMAN | [view interactions] | High throughput | no | no |
| ERC6L_HUMAN | [view interactions] | High throughput | no | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| ADIP_HUMAN | [view interactions] | High throughput | no | yes |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1A_HUMAN | [view interactions] | High throughput | no | no |
| RM35_HUMAN | [view interactions] | High throughput | no | no |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L5_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK2_HUMAN | [view interactions] | High throughput | no | no |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| ZN577_HUMAN | [view interactions] | High throughput | no | yes |
| ZN729_HUMAN | [view interactions] | High throughput | no | no |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCG_HUMAN | [view interactions] | High throughput | no | no |
| M3K10_HUMAN | [view interactions] | High throughput | no | yes |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| LCP2_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| BKRB1_HUMAN | [view interactions] | High throughput | no | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| H2AZ_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| H1T_HUMAN | [view interactions] | High throughput | no | no |
| CMBL_HUMAN | [view interactions] | High throughput | no | no |
| CSAG1_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGR1_HUMAN | [view interactions] | High throughput | no | no |
| SPICE_HUMAN | [view interactions] | High throughput | no | yes |
| CE120_HUMAN | [view interactions] | High throughput | no | no |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| HEN1_HUMAN | [view interactions] | High throughput | no | no |
| SPZ1_HUMAN | [view interactions] | High throughput | no | no |
| RON_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KIF1C_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| SPB1_HUMAN | [view interactions] | High throughput | no | yes |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| BCOR_HUMAN | [view interactions] | High throughput | no | no |
| CDKN3_HUMAN | [view interactions] | High throughput | no | no |