Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAN_HUMAN

GO
G2C
SynGO

GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport (PubMed, PubMed, PubMed). Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed). RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation (PubMed, PubMed). Required for normal progress through mitosis (PubMed, PubMed, PubMed). The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed). Acts as a negative regulator of the kinase activity of VRK1 and VRK2 (PubMed). Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RAN_HUMAN
GO:0003723 RNA binding 35.8779 4 yes
GO:0043168 anion binding 35.1145 4 yes
GO:0000166 nucleotide binding 32.8244 4 yes
GO:0017076 purine nucleotide binding 32.0611 5 yes
GO:0032555 purine ribonucleotide binding 29.7710 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 28.2443 4 yes
GO:0030554 adenyl nucleotide binding 23.6641 6 no
GO:0043169 cation binding 22.1374 4 yes
GO:0046872 metal ion binding 21.3740 5 yes
GO:0019900 kinase binding 21.3740 4 no
GO:0032559 adenyl ribonucleotide binding 21.3740 5 no
GO:0016462 pyrophosphatase activity 16.0305 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 16.0305 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 16.0305 6 yes
GO:0045296 cadherin binding 10.6870 4 yes
GO:0003924 GTPase activity 8.3969 7 yes
GO:0005525 GTP binding 8.3969 5 yes
GO:0019001 guanyl nucleotide binding 8.3969 6 yes
GO:0032561 guanyl ribonucleotide binding 8.3969 5 yes
GO:0000287 magnesium ion binding 4.5802 6 yes
GO:0019003 GDP binding 3.8168 5 yes
GO:0046982 protein heterodimerization activity 3.0534 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAN_HUMAN
GO:0060255 regulation of macromolecule metabolic process 62.5954 4 no
GO:0080090 regulation of primary metabolic process 60.3053 4 no
GO:0048522 positive regulation of cellular process 58.7786 4 yes
GO:0031323 regulation of cellular metabolic process 58.0153 4 no
GO:0048523 negative regulation of cellular process 55.7252 4 no
GO:0009889 regulation of biosynthetic process 49.6183 4 no
GO:0010556 regulation of macromolecule biosynthetic process 48.8550 5 no
GO:0031326 regulation of cellular biosynthetic process 48.8550 5 no
GO:0010468 regulation of gene expression 47.3282 6 no
GO:0009893 positive regulation of metabolic process 45.0382 4 no
GO:0051246 regulation of protein metabolic process 44.2748 5 no
GO:0010604 positive regulation of macromolecule metabolic process 41.9847 5 no
GO:0010646 regulation of cell communication 41.9847 4 no
GO:0009892 negative regulation of metabolic process 38.1679 4 no
GO:0009966 regulation of signal transduction 38.1679 4 no
GO:0010605 negative regulation of macromolecule metabolic process 37.4046 5 no
GO:0051128 regulation of cellular component organization 37.4046 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.8779 5 no
GO:0031325 positive regulation of cellular metabolic process 35.8779 5 no
GO:0031324 negative regulation of cellular metabolic process 32.8244 5 no
GO:0008104 protein localization 32.0611 4 yes
GO:0009891 positive regulation of biosynthetic process 31.2977 5 no
GO:0051252 regulation of RNA metabolic process 31.2977 5 no
GO:0006996 organelle organization 31.2977 4 yes
GO:0009894 regulation of catabolic process 30.5344 4 no
GO:0031328 positive regulation of cellular biosynthetic process 30.5344 6 no
GO:0048584 positive regulation of response to stimulus 29.7710 4 no
GO:0051247 positive regulation of protein metabolic process 29.7710 6 no
GO:0051049 regulation of transport 29.7710 4 yes
GO:0031399 regulation of protein modification process 29.0076 6 no
GO:0010557 positive regulation of macromolecule biosynthetic process 29.0076 6 no
GO:0043067 regulation of programmed cell death 29.0076 4 no
GO:0042981 regulation of apoptotic process 28.2443 5 no
GO:1902531 regulation of intracellular signal transduction 28.2443 5 no
GO:0009890 negative regulation of biosynthetic process 28.2443 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 28.2443 6 no
GO:0031327 negative regulation of cellular biosynthetic process 28.2443 6 no
GO:0022607 cellular component assembly 27.4809 4 no
GO:0010647 positive regulation of cell communication 26.7176 5 no
GO:0023056 positive regulation of signaling 26.7176 4 no
GO:0036211 protein modification process 26.7176 4 no
GO:0043412 macromolecule modification 26.7176 4 no
GO:0048585 negative regulation of response to stimulus 26.7176 4 no
GO:0060341 regulation of cellular localization 26.7176 4 yes
GO:0006355 regulation of DNA-templated transcription 25.9542 7 no
GO:0010648 negative regulation of cell communication 25.9542 5 no
GO:0023057 negative regulation of signaling 25.9542 4 no
GO:2001141 regulation of RNA biosynthetic process 25.9542 6 no
GO:0009968 negative regulation of signal transduction 25.1908 5 no
GO:0043933 protein-containing complex organization 25.1908 4 no
GO:0071702 organic substance transport 24.4275 4 yes
GO:0032880 regulation of protein localization 24.4275 5 yes
GO:0090304 nucleic acid metabolic process 23.6641 4 yes
GO:0009967 positive regulation of signal transduction 23.6641 5 no
GO:0071705 nitrogen compound transport 22.9008 4 yes
GO:0019220 regulation of phosphate metabolic process 22.9008 6 no
GO:0051174 regulation of phosphorus metabolic process 22.9008 5 no
GO:0071310 cellular response to organic substance 22.1374 4 yes
GO:0051248 negative regulation of protein metabolic process 21.3740 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.3740 5 no
GO:0045595 regulation of cell differentiation 20.6107 4 no
GO:0051130 positive regulation of cellular component organization 20.6107 5 no
GO:2000026 regulation of multicellular organismal development 20.6107 4 no
GO:0010629 negative regulation of gene expression 20.6107 7 no
GO:0006796 phosphate-containing compound metabolic process 19.0840 4 yes
GO:0015031 protein transport 18.3206 4 yes
GO:0007010 cytoskeleton organization 17.5573 5 yes
GO:0014070 response to organic cyclic compound 16.7939 4 yes
GO:0006886 intracellular protein transport 15.2672 4 yes
GO:0051050 positive regulation of transport 15.2672 4 yes
GO:0006913 nucleocytoplasmic transport 14.5038 5 yes
GO:0033993 response to lipid 14.5038 4 yes
GO:0051169 nuclear transport 14.5038 4 yes
GO:0033365 protein localization to organelle 13.7405 5 yes
GO:0070201 regulation of establishment of protein localization 12.9771 6 yes
GO:1903829 positive regulation of protein localization 12.2137 5 yes
GO:0071407 cellular response to organic cyclic compound 10.6870 5 yes
GO:0051223 regulation of protein transport 10.6870 5 yes
GO:0071396 cellular response to lipid 9.9237 5 yes
GO:0006259 DNA metabolic process 9.9237 5 yes
GO:0034504 protein localization to nucleus 9.9237 6 yes
GO:0072594 establishment of protein localization to organelle 9.1603 4 yes
GO:0072521 purine-containing compound metabolic process 8.3969 4 yes
GO:0006163 purine nucleotide metabolic process 8.3969 5 yes
GO:0006606 protein import into nucleus 8.3969 5 yes
GO:0006753 nucleoside phosphate metabolic process 8.3969 4 yes
GO:0009117 nucleotide metabolic process 8.3969 5 yes
GO:0019693 ribose phosphate metabolic process 8.3969 4 yes
GO:0032386 regulation of intracellular transport 8.3969 5 yes
GO:0032870 cellular response to hormone stimulus 8.3969 4 yes
GO:0048545 response to steroid hormone 8.3969 4 yes
GO:0051168 nuclear export 8.3969 6 yes
GO:0051170 import into nucleus 8.3969 6 yes
GO:1900180 regulation of protein localization to nucleus 7.6336 6 yes
GO:0009150 purine ribonucleotide metabolic process 7.6336 6 yes
GO:0009259 ribonucleotide metabolic process 7.6336 5 yes
GO:1904951 positive regulation of establishment of protein localization 6.8702 6 yes
GO:0009141 nucleoside triphosphate metabolic process 6.1069 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 6.1069 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 6.1069 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 6.1069 7 yes
GO:0043393 regulation of protein binding 6.1069 4 yes
GO:0046822 regulation of nucleocytoplasmic transport 6.1069 6 yes
GO:1900182 positive regulation of protein localization to nucleus 5.3435 6 yes
GO:0015931 nucleobase-containing compound transport 5.3435 5 yes
GO:0033157 regulation of intracellular protein transport 5.3435 6 yes
GO:0050657 nucleic acid transport 5.3435 6 yes
GO:0050658 RNA transport 5.3435 4 yes
GO:0051099 positive regulation of binding 5.3435 4 yes
GO:0051222 positive regulation of protein transport 5.3435 5 yes
GO:0071383 cellular response to steroid hormone stimulus 4.5802 5 yes
GO:1902850 microtubule cytoskeleton organization involved in mitosis 4.5802 4 yes
GO:0006405 RNA export from nucleus 4.5802 5 yes
GO:0006611 protein export from nucleus 4.5802 5 yes
GO:0031960 response to corticosteroid 4.5802 5 yes
GO:0032092 positive regulation of protein binding 3.8168 5 yes
GO:0032388 positive regulation of intracellular transport 3.8168 5 yes
GO:0042306 regulation of protein import into nucleus 3.8168 7 yes
GO:0051276 chromosome organization 3.8168 5 yes
GO:0090316 positive regulation of intracellular protein transport 3.0534 6 yes
GO:0007052 mitotic spindle organization 3.0534 4 yes
GO:0042307 positive regulation of protein import into nucleus 3.0534 7 yes
GO:0046824 positive regulation of nucleocytoplasmic transport 3.0534 6 yes
GO:0051385 response to mineralocorticoid 3.0534 6 yes
GO:0071384 cellular response to corticosteroid stimulus 2.2901 6 yes
GO:0000055 ribosomal large subunit export from nucleus 2.2901 4 yes
GO:0000056 ribosomal small subunit export from nucleus 2.2901 4 yes
GO:0006404 RNA import into nucleus 2.2901 5 yes
GO:0007286 spermatid development 2.2901 4 yes
GO:0061015 snRNA import into nucleus 1.5267 6 yes
GO:0071389 cellular response to mineralocorticoid stimulus 1.5267 7 yes
GO:0098813 nuclear chromosome segregation 1.5267 4 yes
GO:1902570 protein localization to nucleolus 1.5267 7 yes
GO:0000070 mitotic sister chromatid segregation 1.5267 4 yes
GO:0000819 sister chromatid segregation 1.5267 5 yes
GO:0035281 pre-miRNA export from nucleus 1.5267 6 yes
GO:0046039 GTP metabolic process 1.5267 7 yes
GO:0051030 snRNA transport 1.5267 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NXT1_HUMAN [view interactions] Low throughput no no
XPO2_HUMAN [view entry] [view interactions] Low throughput yes no
MYCB2_HUMAN [view entry] [view interactions] Low throughput yes no
PAK4_HUMAN [view interactions] Low throughput no yes
PAR10_HUMAN [view interactions] Low throughput no yes
RAN_HUMAN [view entry] [view interactions] Low throughput yes no
CDN1B_HUMAN [view interactions] Low throughput no yes
RL7_HUMAN [view entry] [view interactions] Low throughput yes yes
PTMA_HUMAN [view interactions] Low throughput no yes
SPN1_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
RANB9_HUMAN [view entry] [view interactions] Low throughput yes yes
IPO11_HUMAN [view interactions] Low throughput no yes
BCAR1_HUMAN [view interactions] Low throughput no yes
MD2L2_HUMAN [view interactions] Low throughput no yes
RBP10_HUMAN [view interactions] Low throughput no no
TNPO2_HUMAN [view interactions] Low throughput no yes
XPO6_HUMAN [view interactions] Low throughput no yes
NEK9_HUMAN [view interactions] Low throughput no yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
H2AY_HUMAN [view interactions] Low throughput no yes
XRCC1_HUMAN [view entry] [view interactions] Low throughput yes yes
IPO7_HUMAN [view entry] [view interactions] Low throughput yes yes
ESR1_HUMAN [view interactions] Low throughput no no
RPGF3_HUMAN [view interactions] Low throughput no yes
XPO4_HUMAN [view interactions] Low throughput no no
IPO5_HUMAN [view entry] [view interactions] Low throughput yes yes
HERC5_HUMAN [view interactions] Low throughput no yes
PAXI_HUMAN [view interactions] Low throughput no yes
RBP2_HUMAN [view interactions] Low throughput no yes
NEMP1_HUMAN [view interactions] Low throughput no no
NU153_HUMAN [view interactions] Low throughput no yes
RN157_HUMAN [view interactions] Low throughput no no
RCC1_HUMAN [view interactions] Low throughput no yes
RANG_HUMAN [view interactions] Low throughput no no
PAR14_HUMAN [view interactions] Low throughput no yes
IMB1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAGP1_HUMAN [view entry] [view interactions] Low throughput yes yes
NTF2_HUMAN [view interactions] Low throughput no yes
MOG1_HUMAN [view interactions] Low throughput no yes
XPO7_HUMAN [view entry] [view interactions] Low throughput yes yes
TNPO3_HUMAN [view interactions] Low throughput no yes
RIOK2_HUMAN [view interactions] Low throughput no yes
CPEB4_HUMAN [view entry] [view interactions] Low throughput yes no
IF5A1_HUMAN [view interactions] Low throughput no yes
FMR1_HUMAN [view entry] [view interactions] Low throughput yes yes
DIAP3_HUMAN [view interactions] Low throughput no no
CDC7_HUMAN [view interactions] Low throughput no yes
APBA3_HUMAN [view interactions] Low throughput no yes
SMAD4_HUMAN [view interactions] Low throughput no yes
DEAF1_HUMAN [view interactions] Low throughput no yes
MP2K1_HUMAN [view entry] [view interactions] Low throughput yes yes
4ET_HUMAN [view interactions] Low throughput no yes
ASPP2_HUMAN [view interactions] Low throughput no yes
IASPP_HUMAN [view interactions] Low throughput no yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
IMA1_HUMAN [view entry] [view interactions] Low throughput yes yes
RANB3_HUMAN [view interactions] Low throughput no yes
VRK1_HUMAN [view interactions] Low throughput no yes
VRK2_HUMAN [view interactions] Low throughput no no
XPO5_HUMAN [view interactions] Low throughput no yes
IPO13_HUMAN [view interactions] Low throughput no yes
BIRC5_HUMAN [view interactions] Low throughput no no
CDN2A_HUMAN [view interactions] Low throughput no yes
HDAC5_HUMAN [view interactions] Low throughput no yes
DCAF8_HUMAN [view interactions] Low throughput no yes
IF1AX_HUMAN [view interactions] Low throughput no yes
IPKA_HUMAN [view interactions] Low throughput no yes
NXF1_HUMAN [view interactions] Low throughput no yes
TNPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
XPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
XPOT_HUMAN [view interactions] Low throughput no no
NUP50_HUMAN [view interactions] Low throughput no yes
SNF5_HUMAN [view interactions] Low throughput no yes
SIR2_HUMAN [view entry] [view interactions] Low throughput yes yes
NUP54_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
CRCT1_HUMAN [view interactions] High throughput no no
BAP1_HUMAN [view interactions] High throughput no yes
WBP1L_HUMAN [view interactions] High throughput no yes
GATA4_HUMAN [view interactions] High throughput no no
SLN12_HUMAN [view interactions] High throughput no no
ACE2_HUMAN [view interactions] High throughput no no
DPYL5_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
LHX5_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
COA7_HUMAN [view interactions] High throughput no yes
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
PHF23_HUMAN [view interactions] High throughput no yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
MEP50_HUMAN [view interactions] High throughput no yes
RUFY1_HUMAN [view interactions] High throughput no yes
KCD17_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
PAAT_HUMAN [view interactions] High throughput no yes
FBW1A_HUMAN [view interactions] High throughput no yes
CC036_HUMAN [view interactions] High throughput no no
ASXL1_HUMAN [view interactions] High throughput no no
SPSB1_HUMAN [view interactions] High throughput no no
ASXL2_HUMAN [view interactions] High throughput no no
SPY4_HUMAN [view interactions] High throughput no yes
ASXL3_HUMAN [view interactions] High throughput no no
ATG10_HUMAN [view interactions] High throughput no yes
UBP48_HUMAN [view interactions] High throughput no yes
LPAL2_HUMAN [view interactions] High throughput no no
UBE2O_HUMAN [view interactions] High throughput no yes
H3C_HUMAN [view interactions] High throughput no yes
SRS10_HUMAN [view interactions] High throughput no yes
CHMP7_HUMAN [view interactions] High throughput no yes
FND3A_HUMAN [view interactions] High throughput no yes
HAUS8_HUMAN [view interactions] High throughput no yes
HSF1_HUMAN [view interactions] High throughput no yes
LRC56_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
TET5B_HUMAN [view interactions] High throughput no no
MIDN_HUMAN [view interactions] High throughput no no
ASCL4_HUMAN [view interactions] High throughput no no
GOLI_HUMAN [view interactions] High throughput no yes
KT222_HUMAN [view interactions] High throughput no no
RN149_HUMAN [view interactions] High throughput no no
ZN597_HUMAN [view interactions] High throughput no yes
SMC5_HUMAN [view interactions] High throughput no yes
FGD5_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
KAD8_HUMAN [view interactions] High throughput no no
TNIP1_HUMAN [view interactions] High throughput no yes
FAM9A_HUMAN [view interactions] High throughput no no
ATG3_HUMAN [view interactions] High throughput no yes
EF1DL_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
SPAS1_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
CF218_HUMAN [view interactions] High throughput no no
CMA1D_HUMAN [view interactions] High throughput no no
RUAS1_HUMAN [view interactions] High throughput no no
MBPHL_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
ABEC4_HUMAN [view interactions] High throughput no no
ZNG1C_HUMAN [view interactions] High throughput no yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
FND3B_HUMAN [view interactions] High throughput no no
SPRE1_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
TPR_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
U2AF1_HUMAN [view interactions] High throughput no yes
CE126_HUMAN [view interactions] High throughput no no
SF3B6_HUMAN [view interactions] High throughput no yes
NFL_HUMAN [view entry] [view interactions] High throughput yes yes
TRA2B_HUMAN [view interactions] High throughput no yes
SON_HUMAN [view interactions] High throughput no yes
EXOS2_HUMAN [view interactions] High throughput no yes
IRS1_HUMAN [view entry] [view interactions] High throughput yes yes
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
PFD4_HUMAN [view interactions] High throughput no yes
NUP88_HUMAN [view interactions] High throughput no yes
GDE_HUMAN [view entry] [view interactions] High throughput yes no
CK068_HUMAN [view interactions] High throughput no yes
IF6_HUMAN [view interactions] High throughput no yes
NU188_HUMAN [view interactions] High throughput no yes
IMA6_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
RRP44_HUMAN [view interactions] High throughput no yes
NR4A2_HUMAN [view interactions] High throughput no yes
EIF3I_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
IMA7_HUMAN [view interactions] High throughput no yes
NECD_HUMAN [view interactions] High throughput no no
PSA4_HUMAN [view entry] [view interactions] High throughput yes yes
DYRK2_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
SKI2_HUMAN [view interactions] High throughput no yes
RNBP6_HUMAN [view interactions] High throughput no yes
H31_HUMAN [view interactions] High throughput no yes
PSA1_HUMAN [view interactions] High throughput no yes
ARF3_HUMAN [view entry] [view interactions] High throughput yes no
RBBP7_HUMAN [view interactions] High throughput no yes
RS17_HUMAN [view entry] [view interactions] High throughput yes yes
MSL1_HUMAN [view interactions] High throughput no yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
IF1AY_HUMAN [view interactions] High throughput no yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
PHAX_HUMAN [view interactions] High throughput no yes
RBPMS_HUMAN [view interactions] High throughput no no
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
ALG13_HUMAN [view interactions] High throughput no yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
RPR1B_HUMAN [view interactions] High throughput no yes
RL32_HUMAN [view entry] [view interactions] High throughput yes yes
BACH_HUMAN [view entry] [view interactions] High throughput yes yes
SAP18_HUMAN [view interactions] High throughput no yes
DHX15_HUMAN [view interactions] High throughput no yes
SMCA5_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
KDM1A_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
FLNB_HUMAN [view interactions] High throughput no no
TAF6_HUMAN [view interactions] High throughput no no
SAP30_HUMAN [view interactions] High throughput no yes
KMT2A_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
MBD3_HUMAN [view interactions] High throughput no yes
RAD21_HUMAN [view interactions] High throughput no yes
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
HDGF_HUMAN [view interactions] High throughput no yes
CAN1_HUMAN [view entry] [view interactions] High throughput yes yes
SYEP_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
KAP0_HUMAN [view entry] [view interactions] High throughput yes yes
ISG15_HUMAN [view interactions] High throughput no no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
TFAP4_HUMAN [view interactions] High throughput no yes
G6PD_HUMAN [view entry] [view interactions] High throughput yes no
CDK2_HUMAN [view interactions] High throughput no yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
CREB1_HUMAN [view interactions] High throughput no yes
MGN_HUMAN [view interactions] High throughput no yes
H12_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
NUCL_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
PAN2_HUMAN [view interactions] High throughput no no
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
S10A2_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
ASB2_HUMAN [view interactions] High throughput no no
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
ASB16_HUMAN [view interactions] High throughput no no
GARS_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
SYIC_HUMAN [view interactions] High throughput no yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
SYQ_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
OBSL1_HUMAN [view interactions] High throughput no yes
HCFC1_HUMAN [view interactions] High throughput no yes
SUZ12_HUMAN [view interactions] High throughput no no
NCBP2_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
ACLY_HUMAN [view entry] [view interactions] High throughput yes yes
RGPD5_HUMAN [view interactions] High throughput no no
RING2_HUMAN [view interactions] High throughput no yes
SYRC_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
SYMC_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
PPME1_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
CRY2_HUMAN [view interactions] High throughput no yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
U2AF2_HUMAN [view interactions] High throughput no yes
CAP1_HUMAN [view entry] [view interactions] High throughput yes yes
MK13_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
SLX4_HUMAN [view interactions] High throughput no yes
IF2B_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
SLX1_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
AIMP1_HUMAN [view interactions] High throughput no yes
IKKB_HUMAN [view interactions] High throughput no yes
NKX21_HUMAN [view interactions] High throughput no no
PABP4_HUMAN [view entry] [view interactions] High throughput yes yes
ILK_HUMAN [view interactions] High throughput no no
RPTOR_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
TYK2_HUMAN [view interactions] High throughput no no
NU214_HUMAN [view interactions] High throughput no no
CUL2_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
IKIP_HUMAN [view interactions] High throughput no no
IPYR_HUMAN [view interactions] High throughput no yes
NUP98_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
RBBP5_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
STXB2_HUMAN [view interactions] High throughput no no
C170L_HUMAN [view entry] [view interactions] High throughput yes no
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
BRCA1_HUMAN [view interactions] High throughput no yes
HDAC2_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
SYMPK_HUMAN [view interactions] High throughput no yes
SMRC1_HUMAN [view interactions] High throughput no yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
BRAF_HUMAN [view entry] [view interactions] High throughput yes yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
KIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
BMR1A_HUMAN [view interactions] High throughput no no
TSNAX_HUMAN [view interactions] High throughput no yes
PAX6_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC7_HUMAN [view interactions] High throughput no yes
MED12_HUMAN [view interactions] High throughput no yes
SYTL2_HUMAN [view interactions] High throughput no no
KIF1C_HUMAN [view interactions] High throughput no yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
CPSF2_HUMAN [view entry] [view interactions] High throughput yes yes
GRDN_HUMAN [view interactions] High throughput no no
HBP1_HUMAN [view interactions] High throughput no yes
SYLC_HUMAN [view interactions] High throughput no yes
NEMP2_HUMAN [view interactions] High throughput no no
PTC1_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
IMA3_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
RGPD8_HUMAN [view interactions] High throughput no no
AAR2_HUMAN [view interactions] High throughput no no
Z3H7A_HUMAN [view interactions] High throughput no no
NUP62_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
NAA40_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
DLGP5_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
RGPD2_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
CDCA2_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
FOXO1_HUMAN [view interactions] High throughput no yes
IPO9_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
RED1_HUMAN [view interactions] High throughput no no
AKIR1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
RAB25_HUMAN [view interactions] High throughput no no
NEMO_HUMAN [view interactions] High throughput no yes
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
AKIR2_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
RFA2_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
RFA3_HUMAN [view interactions] High throughput no yes
OCRL_HUMAN [view interactions] High throughput no yes
BACH1_HUMAN [view interactions] High throughput no no
RFA4_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
SSR3_HUMAN [view interactions] High throughput no yes
RHG01_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
GPN3_HUMAN [view interactions] High throughput no yes
CTCF_HUMAN [view interactions] High throughput no yes
SMYD3_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
AN32A_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
PPM1G_HUMAN [view interactions] High throughput no no
ATX3_HUMAN [view interactions] High throughput no yes
SET_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
PEX5_HUMAN [view interactions] High throughput no yes
P2RY6_HUMAN [view interactions] High throughput no no
TT39C_HUMAN [view interactions] High throughput no yes
UN93B_HUMAN [view interactions] High throughput no yes
GPN1_HUMAN [view interactions] High throughput no yes
STYX_HUMAN [view interactions] High throughput no yes
SUFU_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
AN32E_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
ARI1_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
SESN2_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
MAP11_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
ZCH18_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
SNIP1_HUMAN [view interactions] High throughput no no
PRD16_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
MECOM_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
GAB2_HUMAN [view interactions] High throughput no yes
CHM4C_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
KIF14_HUMAN [view interactions] High throughput no no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
KIF23_HUMAN [view interactions] High throughput no yes
NCBP1_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
RMC1_HUMAN [view interactions] High throughput no no
INS_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
SPAG7_HUMAN [view interactions] High throughput no yes
FNDC5_HUMAN [view interactions] High throughput no no
SBP2L_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
IGSF3_HUMAN [view interactions] High throughput no yes
CBX5_HUMAN [view interactions] High throughput no yes
BAZ1A_HUMAN [view interactions] High throughput no no
CBX1_HUMAN [view interactions] High throughput no yes
H15_HUMAN [view interactions] High throughput no no
KDF1_HUMAN [view interactions] High throughput no yes
H31T_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
H2B1H_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
BAG5_HUMAN [view entry] [view interactions] High throughput yes no
MLXIP_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
S26A6_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
2ABB_HUMAN [view interactions] High throughput no yes
H2AX_HUMAN [view interactions] High throughput no yes
RGPD4_HUMAN [view interactions] High throughput no no
RGPD1_HUMAN [view interactions] High throughput no no
VRK3_HUMAN [view interactions] High throughput no yes
DTX3_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
ANR49_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
BAG1_HUMAN [view interactions] High throughput no yes
TRPV4_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
IKBA_HUMAN [view interactions] High throughput no yes
AP2S1_HUMAN [view entry] [view interactions] High throughput yes no
ASPP1_HUMAN [view interactions] High throughput no yes
CNBP_HUMAN [view interactions] High throughput no no
TNKS1_HUMAN [view interactions] High throughput no yes
ECM29_HUMAN [view interactions] High throughput no no
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
SHIP2_HUMAN [view interactions] High throughput no yes
GABP1_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
DUX4_HUMAN [view interactions] High throughput no no
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
TIAM1_HUMAN [view entry] [view interactions] High throughput yes yes
NXT2_HUMAN [view interactions] High throughput no yes
TIAM2_HUMAN [view interactions] High throughput no yes
KPCD3_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
MCE1_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
PCNT_HUMAN [view interactions] High throughput no yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
IMA4_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
NUP42_HUMAN [view interactions] High throughput no no
BMI1_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
SUMO1_HUMAN [view entry] [view interactions] High throughput yes yes
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
HNRPU_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
GRSF1_HUMAN [view interactions] High throughput no yes
NUP85_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
RGPD3_HUMAN [view interactions] High throughput no no
NUP93_HUMAN [view interactions] High throughput no yes
NU155_HUMAN [view interactions] High throughput no yes
NUP37_HUMAN [view interactions] High throughput no yes
ASH2L_HUMAN [view interactions] High throughput no yes
RPB9_HUMAN [view interactions] High throughput no yes
NDC1_HUMAN [view interactions] High throughput no yes
PER1_HUMAN [view interactions] High throughput no no
KIFC1_HUMAN [view interactions] High throughput no yes
RBBP4_HUMAN [view interactions] High throughput no yes
NUSAP_HUMAN [view interactions] High throughput no no
TF65_HUMAN [view entry] [view interactions] High throughput yes yes
SKI8_HUMAN [view interactions] High throughput no yes
RHEB_HUMAN [view entry] [view interactions] High throughput yes yes
NU205_HUMAN [view interactions] High throughput no no
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
SMCE1_HUMAN [view interactions] High throughput no yes
PP1RB_HUMAN [view interactions] High throughput no yes
IPO4_HUMAN [view interactions] High throughput no no
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
PO210_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
NU133_HUMAN [view interactions] High throughput no yes
ZBT14_HUMAN [view interactions] High throughput no yes
ANXA4_HUMAN [view interactions] High throughput no no
PHF10_HUMAN [view interactions] High throughput no yes
TRI23_HUMAN [view interactions] High throughput no yes
BRD7_HUMAN [view interactions] High throughput no yes
BAAT_HUMAN [view interactions] High throughput no no
UGGG1_HUMAN [view interactions] High throughput no yes
CHLE_HUMAN [view interactions] High throughput no no
CAN2_HUMAN [view entry] [view interactions] High throughput yes no
ERG1_HUMAN [view interactions] High throughput no no
TEN1L_HUMAN [view interactions] High throughput no no
NUMA1_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
SPCS3_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
IMA5_HUMAN [view entry] [view interactions] High throughput yes yes
AOFB_HUMAN [view entry] [view interactions] High throughput yes yes
SMRC2_HUMAN [view interactions] High throughput no yes
PPARA_HUMAN [view interactions] High throughput no yes
RAE1L_HUMAN [view interactions] High throughput no no
TELT_HUMAN [view interactions] High throughput no no
CCD43_HUMAN [view interactions] High throughput no yes
JMJD7_HUMAN [view interactions] High throughput no yes
AFG2A_HUMAN [view interactions] High throughput no yes
CDS2_HUMAN [view interactions] High throughput no yes
NUP35_HUMAN [view interactions] High throughput no yes
RNF10_HUMAN [view entry] [view interactions] High throughput yes yes
GLE1_HUMAN [view interactions] High throughput no yes
C1D_HUMAN [view interactions] High throughput no yes
NUP58_HUMAN [view interactions] High throughput no yes
ACL7B_HUMAN [view interactions] High throughput no no
TRI31_HUMAN [view interactions] High throughput no no
YIF1A_HUMAN [view interactions] High throughput no yes
ANM1_HUMAN [view interactions] High throughput no yes
SNF8_HUMAN [view interactions] High throughput no yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
ELL2_HUMAN [view interactions] High throughput no no
FOLR1_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
MYCN_HUMAN [view interactions] High throughput no no
EST1A_HUMAN [view interactions] High throughput no yes
DPOA2_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
RPAC2_HUMAN [view interactions] High throughput no no
RNF38_HUMAN [view interactions] High throughput no yes
JUPI1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
RSRC1_HUMAN [view interactions] High throughput no yes
AIMP2_HUMAN [view interactions] High throughput no yes
CIA2B_HUMAN [view interactions] High throughput no yes
HDAC6_HUMAN [view interactions] High throughput no yes