Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAN_HUMAN

GO
G2C
SynGO

GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport (PubMed, PubMed, PubMed). Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed). RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation (PubMed, PubMed). Required for normal progress through mitosis (PubMed, PubMed, PubMed). The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed). Acts as a negative regulator of the kinase activity of VRK1 and VRK2 (PubMed). Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RAN_HUMAN
GO:0003723 RNA binding 36.1111 4 yes
GO:0017076 purine nucleotide binding 25.9259 4 yes
GO:0032555 purine ribonucleotide binding 25.0000 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 25.0000 4 yes
GO:0019900 kinase binding 24.0741 4 no
GO:0019901 protein kinase binding 21.2963 5 no
GO:0046872 metal ion binding 19.4444 4 yes
GO:0045296 cadherin binding 14.8148 4 yes
GO:0016462 pyrophosphatase activity 13.8889 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 13.8889 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 13.8889 6 yes
GO:0003924 GTPase activity 7.4074 7 yes
GO:0005525 GTP binding 7.4074 5 yes
GO:0019001 guanyl nucleotide binding 7.4074 5 yes
GO:0032561 guanyl ribonucleotide binding 7.4074 5 yes
GO:0046982 protein heterodimerization activity 5.5556 4 yes
GO:0000287 magnesium ion binding 4.6296 5 yes
GO:0019003 GDP binding 3.7037 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAN_HUMAN
GO:0060255 regulation of macromolecule metabolic process 69.4444 4 no
GO:0080090 regulation of primary metabolic process 67.5926 4 no
GO:0051171 regulation of nitrogen compound metabolic process 66.6667 4 no
GO:0031323 regulation of cellular metabolic process 63.8889 4 no
GO:0048522 positive regulation of cellular process 62.0370 4 yes
GO:0048523 negative regulation of cellular process 55.5556 4 no
GO:0009893 positive regulation of metabolic process 49.0741 4 no
GO:0051246 regulation of protein metabolic process 47.2222 5 no
GO:0010604 positive regulation of macromolecule metabolic process 45.3704 5 no
GO:0010646 regulation of cell communication 43.5185 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 43.5185 5 no
GO:0010468 regulation of gene expression 42.5926 5 no
GO:0031325 positive regulation of cellular metabolic process 42.5926 5 no
GO:0009892 negative regulation of metabolic process 41.6667 4 no
GO:0010605 negative regulation of macromolecule metabolic process 40.7407 5 no
GO:0009966 regulation of signal transduction 39.8148 4 no
GO:0009889 regulation of biosynthetic process 38.8889 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 38.8889 5 no
GO:0031326 regulation of cellular biosynthetic process 38.8889 5 no
GO:0010556 regulation of macromolecule biosynthetic process 37.0370 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 37.0370 5 no
GO:0031324 negative regulation of cellular metabolic process 36.1111 5 no
GO:0051128 regulation of cellular component organization 36.1111 4 no
GO:0008104 protein localization 35.1852 4 yes
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0071702 organic substance transport 30.5556 4 yes
GO:0071705 nitrogen compound transport 30.5556 4 yes
GO:0051252 regulation of RNA metabolic process 30.5556 5 no
GO:0009894 regulation of catabolic process 29.6296 4 no
GO:0051049 regulation of transport 28.7037 4 yes
GO:0010941 regulation of cell death 28.7037 4 no
GO:0019220 regulation of phosphate metabolic process 28.7037 6 no
GO:0051174 regulation of phosphorus metabolic process 28.7037 5 no
GO:0051247 positive regulation of protein metabolic process 28.7037 6 no
GO:0006996 organelle organization 27.7778 4 yes
GO:0009891 positive regulation of biosynthetic process 27.7778 5 no
GO:0031328 positive regulation of cellular biosynthetic process 27.7778 6 no
GO:0051248 negative regulation of protein metabolic process 27.7778 6 no
GO:0060341 regulation of cellular localization 26.8519 4 yes
GO:0006355 regulation of DNA-templated transcription 26.8519 6 no
GO:1903506 regulation of nucleic acid-templated transcription 26.8519 7 no
GO:2001141 regulation of RNA biosynthetic process 26.8519 6 no
GO:0048584 positive regulation of response to stimulus 26.8519 4 no
GO:0048585 negative regulation of response to stimulus 26.8519 4 no
GO:1902531 regulation of intracellular signal transduction 26.8519 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 26.8519 6 no
GO:0036211 protein modification process 26.8519 4 no
GO:0043412 macromolecule modification 26.8519 4 no
GO:0071310 cellular response to organic substance 25.9259 4 yes
GO:0043067 regulation of programmed cell death 25.9259 5 no
GO:0042325 regulation of phosphorylation 25.9259 7 no
GO:0022607 cellular component assembly 25.9259 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 25.9259 6 no
GO:0015031 protein transport 25.0000 4 yes
GO:0042981 regulation of apoptotic process 25.0000 6 no
GO:0032880 regulation of protein localization 24.0741 5 yes
GO:0010648 negative regulation of cell communication 24.0741 5 no
GO:0023057 negative regulation of signaling 24.0741 4 no
GO:0031329 regulation of cellular catabolic process 24.0741 5 no
GO:0051338 regulation of transferase activity 24.0741 4 no
GO:0010647 positive regulation of cell communication 23.1481 5 no
GO:0023056 positive regulation of signaling 23.1481 4 no
GO:0080134 regulation of response to stress 23.1481 4 no
GO:0006886 intracellular protein transport 22.2222 4 yes
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0033043 regulation of organelle organization 22.2222 5 no
GO:0001932 regulation of protein phosphorylation 21.2963 7 no
GO:0043085 positive regulation of catalytic activity 21.2963 4 no
GO:0009967 positive regulation of signal transduction 20.3704 5 no
GO:0090304 nucleic acid metabolic process 19.4444 4 yes
GO:0014070 response to organic cyclic compound 16.6667 4 yes
GO:0033365 protein localization to organelle 16.6667 5 yes
GO:0051050 positive regulation of transport 16.6667 4 yes
GO:0070201 regulation of establishment of protein localization 16.6667 6 yes
GO:0006796 phosphate-containing compound metabolic process 14.8148 4 yes
GO:0006913 nucleocytoplasmic transport 14.8148 5 yes
GO:0007010 cytoskeleton organization 14.8148 5 yes
GO:0033993 response to lipid 14.8148 4 yes
GO:0051169 nuclear transport 14.8148 4 yes
GO:1903829 positive regulation of protein localization 14.8148 5 yes
GO:0034504 protein localization to nucleus 12.9630 6 yes
GO:0071407 cellular response to organic cyclic compound 12.9630 5 yes
GO:0032386 regulation of intracellular transport 12.0370 5 yes
GO:0051223 regulation of protein transport 12.0370 5 yes
GO:0072594 establishment of protein localization to organelle 12.0370 4 yes
GO:0006606 protein import into nucleus 11.1111 5 yes
GO:0051170 import into nucleus 11.1111 6 yes
GO:1904951 positive regulation of establishment of protein localization 11.1111 6 yes
GO:0006259 DNA metabolic process 10.1852 4 yes
GO:0033157 regulation of intracellular protein transport 9.2593 6 yes
GO:0071396 cellular response to lipid 9.2593 5 yes
GO:1900180 regulation of protein localization to nucleus 9.2593 6 yes
GO:0015931 nucleobase-containing compound transport 8.3333 5 yes
GO:0032870 cellular response to hormone stimulus 8.3333 4 yes
GO:0046822 regulation of nucleocytoplasmic transport 8.3333 6 yes
GO:0050657 nucleic acid transport 8.3333 6 yes
GO:0050658 RNA transport 8.3333 4 yes
GO:0051099 positive regulation of binding 8.3333 4 yes
GO:1900182 positive regulation of protein localization to nucleus 8.3333 6 yes
GO:0032388 positive regulation of intracellular transport 7.4074 5 yes
GO:0043393 regulation of protein binding 7.4074 4 yes
GO:0048545 response to steroid hormone 7.4074 4 yes
GO:0051222 positive regulation of protein transport 7.4074 5 yes
GO:0051168 nuclear export 6.4815 6 yes
GO:0090316 positive regulation of intracellular protein transport 6.4815 6 yes
GO:0031960 response to corticosteroid 5.5556 5 yes
GO:0046824 positive regulation of nucleocytoplasmic transport 5.5556 6 yes
GO:0006611 protein export from nucleus 4.6296 5 yes
GO:0032092 positive regulation of protein binding 4.6296 5 yes
GO:1902850 microtubule cytoskeleton organization involved in mitosis 4.6296 4 yes
GO:0000055 ribosomal large subunit export from nucleus 3.7037 4 yes
GO:0000056 ribosomal small subunit export from nucleus 3.7037 4 yes
GO:0006163 purine nucleotide metabolic process 3.7037 5 yes
GO:0006405 RNA export from nucleus 3.7037 5 yes
GO:0006753 nucleoside phosphate metabolic process 3.7037 4 yes
GO:0009117 nucleotide metabolic process 3.7037 5 yes
GO:0009141 nucleoside triphosphate metabolic process 3.7037 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 3.7037 6 yes
GO:0009150 purine ribonucleotide metabolic process 3.7037 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 3.7037 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 3.7037 7 yes
GO:0009259 ribonucleotide metabolic process 3.7037 5 yes
GO:0019693 ribose phosphate metabolic process 3.7037 4 yes
GO:0042306 regulation of protein import into nucleus 3.7037 7 yes
GO:0042307 positive regulation of protein import into nucleus 3.7037 7 yes
GO:0051276 chromosome organization 3.7037 5 yes
GO:0051385 response to mineralocorticoid 3.7037 6 yes
GO:0071383 cellular response to steroid hormone stimulus 3.7037 5 yes
GO:0072521 purine-containing compound metabolic process 3.7037 4 yes
GO:0006404 RNA import into nucleus 2.7778 5 yes
GO:0007052 mitotic spindle organization 2.7778 4 yes
GO:0071384 cellular response to corticosteroid stimulus 2.7778 6 yes
GO:0000070 mitotic sister chromatid segregation 1.8519 4 yes
GO:0000819 sister chromatid segregation 1.8519 4 yes
GO:0007286 spermatid development 1.8519 4 yes
GO:0035281 pre-miRNA export from nucleus 1.8519 6 yes
GO:0046039 GTP metabolic process 1.8519 7 yes
GO:0051030 snRNA transport 1.8519 5 yes
GO:0061015 snRNA import into nucleus 1.8519 6 yes
GO:0071389 cellular response to mineralocorticoid stimulus 1.8519 7 yes
GO:1902570 protein localization to nucleolus 1.8519 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in RAN_HUMAN
DOID:331 central nervous system disease 4.6296 3 no
DOID:1289 neurodegenerative disease 2.7778 4 no
DOID:936 brain disease 1.8519 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
IMA1_HUMAN [view entry] [view interactions] Low throughput yes yes
RANB3_HUMAN [view interactions] Low throughput no yes
VRK1_HUMAN [view interactions] Low throughput no yes
VRK2_HUMAN [view interactions] Low throughput no no
XPO5_HUMAN [view interactions] Low throughput no yes
IPO13_HUMAN [view interactions] Low throughput no yes
BIRC5_HUMAN [view interactions] Low throughput no no
CDN2A_HUMAN [view interactions] Low throughput no yes
HDAC5_HUMAN [view interactions] Low throughput no yes
DCAF8_HUMAN [view interactions] Low throughput no yes
IF1AX_HUMAN [view interactions] Low throughput no yes
IPKA_HUMAN [view interactions] Low throughput no yes
NXF1_HUMAN [view interactions] Low throughput no yes
TNPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
XPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
XPOT_HUMAN [view interactions] Low throughput no no
SNF5_HUMAN [view interactions] Low throughput no yes
NXT1_HUMAN [view interactions] Low throughput no no
XPO2_HUMAN [view entry] [view interactions] Low throughput yes no
MYCB2_HUMAN [view entry] [view interactions] Low throughput yes no
PAK4_HUMAN [view interactions] Low throughput no yes
PAR10_HUMAN [view interactions] Low throughput no yes
RAN_HUMAN [view entry] [view interactions] Low throughput yes no
PTMA_HUMAN [view interactions] Low throughput no yes
CDN1B_HUMAN [view interactions] Low throughput no yes
RL7_HUMAN [view entry] [view interactions] Low throughput yes yes
SPN1_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR2_HUMAN [view entry] [view interactions] Low throughput yes yes
RANB9_HUMAN [view entry] [view interactions] Low throughput yes yes
IPO11_HUMAN [view interactions] Low throughput no yes
TNPO3_HUMAN [view interactions] Low throughput no yes
BCAR1_HUMAN [view interactions] Low throughput no yes
MD2L2_HUMAN [view interactions] Low throughput no yes
RBP10_HUMAN [view interactions] Low throughput no no
TNPO2_HUMAN [view interactions] Low throughput no yes
XPO6_HUMAN [view interactions] Low throughput no yes
NEK9_HUMAN [view interactions] Low throughput no yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
H2AY_HUMAN [view interactions] Low throughput no yes
XRCC1_HUMAN [view entry] [view interactions] Low throughput yes yes
IPO7_HUMAN [view entry] [view interactions] Low throughput yes yes
ESR1_HUMAN [view interactions] Low throughput no no
RPGF3_HUMAN [view interactions] Low throughput no yes
RIOK2_HUMAN [view interactions] Low throughput no yes
CPEB4_HUMAN [view entry] [view interactions] Low throughput yes no
IF5A1_HUMAN [view interactions] Low throughput no yes
XPO4_HUMAN [view interactions] Low throughput no no
PAXI_HUMAN [view interactions] Low throughput no yes
IPO5_HUMAN [view entry] [view interactions] Low throughput yes yes
FMR1_HUMAN [view entry] [view interactions] Low throughput yes yes
DIAP3_HUMAN [view interactions] Low throughput no no
CDC7_HUMAN [view interactions] Low throughput no yes
APBA3_HUMAN [view interactions] Low throughput no yes
SMAD4_HUMAN [view interactions] Low throughput no yes
DEAF1_HUMAN [view interactions] Low throughput no yes
MP2K1_HUMAN [view entry] [view interactions] Low throughput yes yes
4ET_HUMAN [view interactions] Low throughput no yes
HERC5_HUMAN [view interactions] Low throughput no yes
RBP2_HUMAN [view interactions] Low throughput no yes
NEMP1_HUMAN [view interactions] Low throughput no no
NU153_HUMAN [view interactions] Low throughput no yes
PAR14_HUMAN [view interactions] Low throughput no yes
RCC1_HUMAN [view interactions] Low throughput no yes
RANG_HUMAN [view interactions] Low throughput no no
IMB1_HUMAN [view entry] [view interactions] Low throughput yes yes
MOG1_HUMAN [view interactions] Low throughput no yes
NTF2_HUMAN [view interactions] Low throughput no yes
RAGP1_HUMAN [view entry] [view interactions] Low throughput yes yes
XPO7_HUMAN [view entry] [view interactions] Low throughput yes yes
IASPP_HUMAN [view interactions] Low throughput no yes
ASPP2_HUMAN [view interactions] Low throughput no yes
H31T_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
MLXIP_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
S26A6_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
H2AX_HUMAN [view interactions] High throughput no yes
RGPD4_HUMAN [view interactions] High throughput no no
2ABB_HUMAN [view interactions] High throughput no yes
RGPD1_HUMAN [view interactions] High throughput no no
DTX3_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
VRK3_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
BAG1_HUMAN [view interactions] High throughput no yes
ANR49_HUMAN [view interactions] High throughput no yes
AP2S1_HUMAN [view entry] [view interactions] High throughput yes no
CNBP_HUMAN [view interactions] High throughput no no
TNKS1_HUMAN [view interactions] High throughput no yes
ECM29_HUMAN [view interactions] High throughput no no
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
SHIP2_HUMAN [view interactions] High throughput no yes
TRPV4_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
GABP1_HUMAN [view interactions] High throughput no yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
ASPP1_HUMAN [view interactions] High throughput no yes
NXT2_HUMAN [view interactions] High throughput no yes
IKBA_HUMAN [view interactions] High throughput no yes
KPCD3_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
MCE1_HUMAN [view interactions] High throughput no yes
TIAM1_HUMAN [view entry] [view interactions] High throughput yes yes
PCNT_HUMAN [view interactions] High throughput no yes
TIAM2_HUMAN [view interactions] High throughput no yes
IMA4_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
NUP42_HUMAN [view interactions] High throughput no no
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
SUMO3_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
SUMO1_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
BMI1_HUMAN [view interactions] High throughput no yes
GRSF1_HUMAN [view interactions] High throughput no yes
NUP85_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
RGPD3_HUMAN [view interactions] High throughput no no
NUP93_HUMAN [view interactions] High throughput no yes
NU155_HUMAN [view interactions] High throughput no yes
NUP37_HUMAN [view interactions] High throughput no yes
ASH2L_HUMAN [view interactions] High throughput no yes
ZBT14_HUMAN [view interactions] High throughput no yes
NDC1_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
KIFC1_HUMAN [view interactions] High throughput no yes
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
NUSAP_HUMAN [view interactions] High throughput no no
PP1RB_HUMAN [view interactions] High throughput no yes
WDR61_HUMAN [view interactions] High throughput no yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
NU205_HUMAN [view interactions] High throughput no no
RHEB_HUMAN [view entry] [view interactions] High throughput yes yes
SMCE1_HUMAN [view interactions] High throughput no yes
TF65_HUMAN [view entry] [view interactions] High throughput yes yes
IPO4_HUMAN [view interactions] High throughput no no
RBBP4_HUMAN [view interactions] High throughput no yes
PO210_HUMAN [view interactions] High throughput no yes
PPARA_HUMAN [view interactions] High throughput no yes
NU133_HUMAN [view interactions] High throughput no yes
RPB9_HUMAN [view interactions] High throughput no yes
NUP50_HUMAN [view interactions] High throughput no yes
PER1_HUMAN [view interactions] High throughput no no
PHF10_HUMAN [view interactions] High throughput no yes
AOFB_HUMAN [view entry] [view interactions] High throughput yes yes
BRD7_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
UGGG1_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
TEN1L_HUMAN [view interactions] High throughput no no
ERG1_HUMAN [view interactions] High throughput no no
CAN2_HUMAN [view interactions] High throughput no no
NUMA1_HUMAN [view interactions] High throughput no yes
CHLE_HUMAN [view interactions] High throughput no no
SPCS3_HUMAN [view interactions] High throughput no yes
BAAT_HUMAN [view interactions] High throughput no no
IMA5_HUMAN [view entry] [view interactions] High throughput yes yes
TRI23_HUMAN [view interactions] High throughput no yes
SMRC2_HUMAN [view interactions] High throughput no yes
ANXA4_HUMAN [view interactions] High throughput no no
RAE1L_HUMAN [view interactions] High throughput no no
CIA2B_HUMAN [view interactions] High throughput no yes
CCD43_HUMAN [view interactions] High throughput no yes
NUP54_HUMAN [view interactions] High throughput no yes
AFG2H_HUMAN [view interactions] High throughput no yes
RSRC1_HUMAN [view interactions] High throughput no yes
NUP35_HUMAN [view interactions] High throughput no yes
JUPI1_HUMAN [view interactions] High throughput no yes
GLE1_HUMAN [view interactions] High throughput no yes
RPAC2_HUMAN [view interactions] High throughput no no
NUP58_HUMAN [view interactions] High throughput no yes
DPOA2_HUMAN [view interactions] High throughput no yes
ATG3_HUMAN [view interactions] High throughput no yes
EST1A_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
ELL2_HUMAN [view interactions] High throughput no no
SNF8_HUMAN [view interactions] High throughput no yes
YIF1A_HUMAN [view interactions] High throughput no yes
ACL7B_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view interactions] High throughput no yes
C1D_HUMAN [view interactions] High throughput no yes
RNF10_HUMAN [view entry] [view interactions] High throughput yes yes
CDS2_HUMAN [view interactions] High throughput no yes
JMJD7_HUMAN [view interactions] High throughput no yes
TPR_HUMAN [view interactions] High throughput no yes
TELT_HUMAN [view interactions] High throughput no no
U2AF1_HUMAN [view interactions] High throughput no yes
DPYL5_HUMAN [view entry] [view interactions] High throughput yes yes
SF3B6_HUMAN [view interactions] High throughput no yes
SLN12_HUMAN [view interactions] High throughput no no
TRA2B_HUMAN [view interactions] High throughput no yes
WBP1L_HUMAN [view interactions] High throughput no yes
SON_HUMAN [view interactions] High throughput no yes
CRCT1_HUMAN [view interactions] High throughput no no
EXOS2_HUMAN [view interactions] High throughput no yes
PHF23_HUMAN [view interactions] High throughput no yes
LHX5_HUMAN [view interactions] High throughput no no
PFD4_HUMAN [view interactions] High throughput no yes
COA7_HUMAN [view interactions] High throughput no yes
GDE_HUMAN [view entry] [view interactions] High throughput yes no
MEP50_HUMAN [view interactions] High throughput no yes
IF6_HUMAN [view interactions] High throughput no yes
ATG10_HUMAN [view interactions] High throughput no yes
IMA6_HUMAN [view interactions] High throughput no yes
SPY4_HUMAN [view interactions] High throughput no yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
KCD17_HUMAN [view interactions] High throughput no yes
RRP44_HUMAN [view interactions] High throughput no yes
SPSB1_HUMAN [view interactions] High throughput no no
EIF3I_HUMAN [view interactions] High throughput no yes
CC036_HUMAN [view interactions] High throughput no no
IMA7_HUMAN [view interactions] High throughput no yes
PAAT_HUMAN [view interactions] High throughput no yes
PSA4_HUMAN [view entry] [view interactions] High throughput yes yes
LPAL2_HUMAN [view interactions] High throughput no no
PSB5_HUMAN [view interactions] High throughput no yes
RUAS1_HUMAN [view interactions] High throughput no no
SKIV2_HUMAN [view entry] [view interactions] High throughput yes yes
OD3L2_HUMAN [view interactions] High throughput no no
RNBP6_HUMAN [view interactions] High throughput no yes
CF218_HUMAN [view interactions] High throughput no no
H31_HUMAN [view interactions] High throughput no yes
SPAS1_HUMAN [view interactions] High throughput no no
PSA1_HUMAN [view interactions] High throughput no yes
EF1DL_HUMAN [view interactions] High throughput no no
ARF3_HUMAN [view entry] [view interactions] High throughput yes no
FAM9A_HUMAN [view interactions] High throughput no no
RBBP7_HUMAN [view interactions] High throughput no yes
KAD8_HUMAN [view interactions] High throughput no no
RS17_HUMAN [view entry] [view interactions] High throughput yes yes
FGD5_HUMAN [view interactions] High throughput no yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
ZN597_HUMAN [view interactions] High throughput no yes
IF1AY_HUMAN [view interactions] High throughput no yes
KT222_HUMAN [view interactions] High throughput no no
PHAX_HUMAN [view interactions] High throughput no yes
ASCL4_HUMAN [view interactions] High throughput no no
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
TET5B_HUMAN [view interactions] High throughput no no
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
LRC56_HUMAN [view interactions] High throughput no no
RL32_HUMAN [view entry] [view interactions] High throughput yes yes
HAUS8_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
CHMP7_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
H3C_HUMAN [view interactions] High throughput no yes
Z3H7A_HUMAN [view interactions] High throughput no no
ABEC4_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
MBPHL_HUMAN [view interactions] High throughput no no
NAA40_HUMAN [view interactions] High throughput no no
CBWD3_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
OPTN_HUMAN [view interactions] High throughput no yes
SPRE1_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
CE126_HUMAN [view interactions] High throughput no no
NFL_HUMAN [view entry] [view interactions] High throughput yes yes
IRS1_HUMAN [view entry] [view interactions] High throughput yes yes
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
NUP88_HUMAN [view interactions] High throughput no yes
CK068_HUMAN [view interactions] High throughput no yes
NU188_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
NR4A2_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
NECD_HUMAN [view interactions] High throughput no no
DYRK2_HUMAN [view interactions] High throughput no yes
MSL1_HUMAN [view interactions] High throughput no yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
RBPMS_HUMAN [view interactions] High throughput no no
ALG13_HUMAN [view interactions] High throughput no yes
RPR1B_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
TAF6_HUMAN [view interactions] High throughput no no
KMT2A_HUMAN [view interactions] High throughput no yes
RAD21_HUMAN [view interactions] High throughput no yes
HDGF_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
ISG15_HUMAN [view interactions] High throughput no no
TFAP4_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
MGN_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
PAN2_HUMAN [view interactions] High throughput no no
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
ASB2_HUMAN [view interactions] High throughput no no
ASB16_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
SUZ12_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
PPME1_HUMAN [view interactions] High throughput no yes
CRY2_HUMAN [view interactions] High throughput no yes
RGPD5_HUMAN [view interactions] High throughput no no
U2AF2_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
IF2B_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
NKX21_HUMAN [view interactions] High throughput no no
MK13_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
SLX4_HUMAN [view interactions] High throughput no yes
NU214_HUMAN [view interactions] High throughput no no
SLX1_HUMAN [view interactions] High throughput no yes
IKIP_HUMAN [view interactions] High throughput no no
IKKB_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
ILK_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
TYK2_HUMAN [view interactions] High throughput no no
RN157_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
NUP98_HUMAN [view interactions] High throughput no no
YAP1_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
C170L_HUMAN [view entry] [view interactions] High throughput yes no
BRAF_HUMAN [view interactions] High throughput no yes
BMR1A_HUMAN [view interactions] High throughput no no
UBC9_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
MED12_HUMAN [view interactions] High throughput no yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
KIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
HBP1_HUMAN [view interactions] High throughput no yes
PAX6_HUMAN [view interactions] High throughput no no
PTC1_HUMAN [view entry] [view interactions] High throughput yes yes
U5S1_HUMAN [view interactions] High throughput no yes
KIF1C_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
GRDN_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
AKIR1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
IPO9_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
CDCA2_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
RGPD2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP5_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
NUP62_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
RGPD8_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
IMA3_HUMAN [view interactions] High throughput no yes
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
NEMP2_HUMAN [view interactions] High throughput no no
BACH1_HUMAN [view interactions] High throughput no no
AKIR2_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
CTCF_HUMAN [view interactions] High throughput no yes
OCRL_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
RHG01_HUMAN [view entry] [view interactions] High throughput yes yes
ATX3_HUMAN [view interactions] High throughput no yes
GPN3_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
SMYD3_HUMAN [view interactions] High throughput no yes
P2RY6_HUMAN [view interactions] High throughput no no
AN32A_HUMAN [view interactions] High throughput no yes
UN93B_HUMAN [view interactions] High throughput no yes
PPM1G_HUMAN [view interactions] High throughput no no
STYX_HUMAN [view interactions] High throughput no yes
SET_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
PEX5_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
TT39C_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
GPN1_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
SUFU_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
AN32E_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
ARI1_HUMAN [view interactions] High throughput no yes
SNIP1_HUMAN [view interactions] High throughput no no
SESN2_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
MAP11_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
PRD16_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
GAB2_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
BRD4_HUMAN [view interactions] High throughput no yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP1_HUMAN [view interactions] High throughput no yes
RMC1_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
SPAG7_HUMAN [view interactions] High throughput no yes
CBX5_HUMAN [view interactions] High throughput no yes
SBP2L_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
IGSF3_HUMAN [view interactions] High throughput no yes
KDF1_HUMAN [view interactions] High throughput no yes
BAZ1A_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
H15_HUMAN [view interactions] High throughput no no
RIN3_HUMAN [view interactions] High throughput no yes
H2B1H_HUMAN [view interactions] High throughput no yes
BAG5_HUMAN [view entry] [view interactions] High throughput yes no
PSDE_HUMAN [view entry] [view interactions] Computational yes yes
NU160_HUMAN [view interactions] Computational no no
FOXO1_HUMAN [view interactions] Computational no yes
1433Z_HUMAN [view entry] [view interactions] Computational yes yes
1433F_HUMAN [view entry] [view interactions] Computational yes yes
HDAC1_HUMAN [view interactions] Computational no no
1433S_HUMAN [view entry] [view interactions] Computational yes yes
EF1A1_HUMAN [view entry] [view interactions] Computational yes yes
FOXO3_HUMAN [view interactions] Computational no yes
FOXO4_HUMAN [view interactions] Computational no no
NUP43_HUMAN [view interactions] Computational no yes
TCPB_HUMAN [view entry] [view interactions] Computational yes yes
1433T_HUMAN [view entry] [view interactions] Computational yes yes
P121A_HUMAN [view interactions] Computational no yes
RCC1L_HUMAN [view interactions] Computational no yes
NMD3_HUMAN [view interactions] Computational no no
RS2_HUMAN [view entry] [view interactions] Computational yes yes
HDAC4_HUMAN [view interactions] Computational no yes
P121C_HUMAN [view interactions] Computational no yes
HDAC6_HUMAN [view interactions] Computational no yes
NFAC1_HUMAN [view interactions] Computational no no
NPM_HUMAN [view entry] [view interactions] Computational yes yes
EF1G_HUMAN [view entry] [view interactions] Computational yes yes
HDAC9_HUMAN [view interactions] Computational no yes
NFAC2_HUMAN [view interactions] Computational no yes
SEC13_HUMAN [view entry] [view interactions] Computational yes yes
1433B_HUMAN [view entry] [view interactions] Computational yes yes
IPO8_HUMAN [view interactions] Computational no no
SEH1_HUMAN [view interactions] Computational no no
TPX2_HUMAN [view interactions] Computational no yes
NCBP2_HUMAN [view interactions] Computational no yes
TCPA_HUMAN [view entry] [view interactions] Computational yes yes
TCPZ_HUMAN [view entry] [view interactions] Computational yes yes
1433G_HUMAN [view entry] [view interactions] Computational yes yes
H2AZ_HUMAN [view interactions] Computational no yes
EF1A2_HUMAN [view entry] [view interactions] Computational yes yes
1433E_HUMAN [view entry] [view interactions] Computational yes yes
NCB2L_HUMAN [view interactions] Computational no no
TCPD_HUMAN [view entry] [view interactions] Computational yes yes
H2AV_HUMAN [view interactions] Computational no yes
SCYL1_HUMAN [view interactions] Computational no yes
AAAS_HUMAN [view interactions] Computational no yes
AGO2_HUMAN [view interactions] Computational no yes