PRDX2_HUMAN
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRDX2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 32.7869 | 4 | no |
| GO:0000166 | nucleotide binding | 31.1475 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.3279 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.0492 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.0492 | 4 | no |
| GO:0043169 | cation binding | 26.2295 | 4 | no |
| GO:0046872 | metal ion binding | 26.2295 | 5 | no |
| GO:0003723 | RNA binding | 23.7705 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 22.9508 | 6 | no |
| GO:0008379 | thioredoxin peroxidase activity | 3.2787 | 5 | yes |
| GO:0140824 | thioredoxin-dependent peroxiredoxin activity | 3.2787 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRDX2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.9180 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 49.1803 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.3607 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.0820 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 44.2623 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 41.8033 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.8033 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.9836 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 40.9836 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 39.3443 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.5246 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 38.5246 | 5 | no |
| GO:0022607 | cellular component assembly | 36.8852 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.2459 | 5 | no |
| GO:0006996 | organelle organization | 32.7869 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.7869 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 32.7869 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.7869 | 5 | yes |
| GO:0010468 | regulation of gene expression | 31.9672 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.9672 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 31.1475 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 29.5082 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 28.6885 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 28.6885 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 28.6885 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 27.8689 | 5 | no |
| GO:0008104 | protein localization | 27.0492 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.0492 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.0492 | 6 | no |
| GO:0060341 | regulation of cellular localization | 27.0492 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.2295 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 26.2295 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 25.4098 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.4098 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.4098 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.4098 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 25.4098 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 25.4098 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 24.5902 | 6 | no |
| GO:0043933 | protein-containing complex organization | 24.5902 | 4 | no |
| GO:0051049 | regulation of transport | 24.5902 | 4 | no |
| GO:0032880 | regulation of protein localization | 24.5902 | 5 | no |
| GO:0009894 | regulation of catabolic process | 24.5902 | 4 | no |
| GO:0043412 | macromolecule modification | 23.7705 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.7705 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.7705 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 22.9508 | 7 | no |
| GO:0036211 | protein modification process | 22.9508 | 4 | no |
| GO:0071702 | organic substance transport | 22.9508 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.9508 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.1311 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.1311 | 5 | no |
| GO:0071705 | nitrogen compound transport | 22.1311 | 4 | no |
| GO:0033043 | regulation of organelle organization | 22.1311 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 22.1311 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 22.1311 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.3115 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.3115 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 20.4918 | 5 | no |
| GO:1903829 | positive regulation of protein localization | 20.4918 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.4918 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.4918 | 6 | no |
| GO:0071310 | cellular response to organic substance | 20.4918 | 4 | no |
| GO:0080134 | regulation of response to stress | 20.4918 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 19.6721 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 18.0328 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 17.2131 | 4 | yes |
| GO:0043069 | negative regulation of programmed cell death | 17.2131 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 17.2131 | 4 | yes |
| GO:0043066 | negative regulation of apoptotic process | 16.3934 | 6 | yes |
| GO:0033993 | response to lipid | 15.5738 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 13.9344 | 4 | yes |
| GO:0060284 | regulation of cell development | 13.9344 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 13.1148 | 6 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 12.2951 | 5 | yes |
| GO:0062197 | cellular response to chemical stress | 10.6557 | 4 | yes |
| GO:0030155 | regulation of cell adhesion | 9.8361 | 4 | yes |
| GO:0034599 | cellular response to oxidative stress | 9.8361 | 4 | yes |
| GO:0050865 | regulation of cell activation | 9.0164 | 4 | yes |
| GO:0002694 | regulation of leukocyte activation | 8.1967 | 4 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 8.1967 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 8.1967 | 4 | yes |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 8.1967 | 5 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 8.1967 | 6 | yes |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 7.3770 | 6 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 7.3770 | 4 | yes |
| GO:0050863 | regulation of T cell activation | 7.3770 | 6 | yes |
| GO:0051249 | regulation of lymphocyte activation | 7.3770 | 5 | yes |
| GO:1903706 | regulation of hemopoiesis | 7.3770 | 4 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 6.5574 | 7 | yes |
| GO:0045596 | negative regulation of cell differentiation | 6.5574 | 5 | yes |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 5.7377 | 7 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 5.7377 | 5 | yes |
| GO:0042110 | T cell activation | 5.7377 | 4 | yes |
| GO:1903034 | regulation of response to wounding | 5.7377 | 5 | yes |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 5.7377 | 6 | yes |
| GO:0002683 | negative regulation of immune system process | 4.9180 | 4 | yes |
| GO:0042743 | hydrogen peroxide metabolic process | 4.9180 | 4 | yes |
| GO:0045580 | regulation of T cell differentiation | 4.9180 | 7 | yes |
| GO:0045619 | regulation of lymphocyte differentiation | 4.9180 | 6 | yes |
| GO:0048732 | gland development | 4.9180 | 4 | yes |
| GO:1902105 | regulation of leukocyte differentiation | 4.9180 | 5 | yes |
| GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 4.0984 | 7 | yes |
| GO:0002237 | response to molecule of bacterial origin | 4.0984 | 4 | yes |
| GO:0007162 | negative regulation of cell adhesion | 4.0984 | 5 | yes |
| GO:0010310 | regulation of hydrogen peroxide metabolic process | 4.0984 | 6 | yes |
| GO:0010721 | negative regulation of cell development | 4.0984 | 6 | yes |
| GO:0032496 | response to lipopolysaccharide | 4.0984 | 4 | yes |
| GO:0042744 | hydrogen peroxide catabolic process | 4.0984 | 4 | yes |
| GO:0048534 | hematopoietic or lymphoid organ development | 4.0984 | 4 | yes |
| GO:0048538 | thymus development | 4.0984 | 5 | yes |
| GO:0050818 | regulation of coagulation | 4.0984 | 4 | yes |
| GO:0061041 | regulation of wound healing | 4.0984 | 6 | yes |
| GO:0097191 | extrinsic apoptotic signaling pathway | 4.0984 | 4 | yes |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 3.2787 | 7 | yes |
| GO:0030193 | regulation of blood coagulation | 3.2787 | 4 | yes |
| GO:0032943 | mononuclear cell proliferation | 3.2787 | 4 | yes |
| GO:0042098 | T cell proliferation | 3.2787 | 5 | yes |
| GO:0046651 | lymphocyte proliferation | 3.2787 | 4 | yes |
| GO:0050866 | negative regulation of cell activation | 3.2787 | 5 | yes |
| GO:1901099 | negative regulation of signal transduction in absence of ligand | 3.2787 | 6 | yes |
| GO:0002695 | negative regulation of leukocyte activation | 2.4590 | 5 | yes |
| GO:0002832 | negative regulation of response to biotic stimulus | 2.4590 | 5 | yes |
| GO:0006801 | superoxide metabolic process | 2.4590 | 4 | yes |
| GO:0019430 | removal of superoxide radicals | 2.4590 | 4 | yes |
| GO:0022408 | negative regulation of cell-cell adhesion | 2.4590 | 6 | yes |
| GO:0043029 | T cell homeostasis | 2.4590 | 4 | yes |
| GO:0050820 | positive regulation of coagulation | 2.4590 | 5 | yes |
| GO:0050868 | negative regulation of T cell activation | 2.4590 | 7 | yes |
| GO:0051250 | negative regulation of lymphocyte activation | 2.4590 | 6 | yes |
| GO:1903036 | positive regulation of response to wounding | 2.4590 | 5 | yes |
| GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 2.4590 | 7 | yes |
| GO:0002357 | defense response to tumor cell | 1.6393 | 4 | yes |
| GO:0030194 | positive regulation of blood coagulation | 1.6393 | 5 | yes |
| GO:0031664 | regulation of lipopolysaccharide-mediated signaling pathway | 1.6393 | 5 | yes |
| GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway | 1.6393 | 6 | yes |
| GO:0045581 | negative regulation of T cell differentiation | 1.6393 | 8 | yes |
| GO:0045620 | negative regulation of lymphocyte differentiation | 1.6393 | 7 | yes |
| GO:0090303 | positive regulation of wound healing | 1.6393 | 6 | yes |
| GO:1900048 | positive regulation of hemostasis | 1.6393 | 4 | yes |
| GO:1902106 | negative regulation of leukocyte differentiation | 1.6393 | 6 | yes |
| GO:1903707 | negative regulation of hemopoiesis | 1.6393 | 5 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PARK7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TXND5_HUMAN | [view interactions] | Low throughput | no | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CDK1_HUMAN | [view interactions] | Low throughput | no | no |
| DNM3A_HUMAN | [view interactions] | Low throughput | no | yes |
| THIO_HUMAN | [view interactions] | Low throughput | no | yes |
| STAT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP4_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | High throughput | no | yes |
| MAK_HUMAN | [view interactions] | High throughput | no | no |
| COP1_HUMAN | [view interactions] | High throughput | no | no |
| APOE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMU1_HUMAN | [view interactions] | High throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| YAF2_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIE_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NEK2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP56_HUMAN | [view interactions] | High throughput | no | yes |
| COMP_HUMAN | [view interactions] | High throughput | no | no |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| AKP13_HUMAN | [view interactions] | High throughput | no | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| M4K5_HUMAN | [view interactions] | High throughput | no | no |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F1712_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPC12_HUMAN | [view interactions] | High throughput | no | yes |
| ANR40_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDCL3_HUMAN | [view interactions] | High throughput | no | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PANK4_HUMAN | [view interactions] | High throughput | no | no |
| TXND9_HUMAN | [view interactions] | High throughput | no | yes |
| TCPW_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHLP_HUMAN | [view interactions] | High throughput | no | yes |
| PCKGC_HUMAN | [view interactions] | High throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| NALP7_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| FOLR1_HUMAN | [view interactions] | High throughput | no | no |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| RNF8_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| ASXL3_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| CFAH_HUMAN | [view interactions] | High throughput | no | no |
| TET5C_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| SAT1_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| UTY_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX4_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CD320_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| 2AAB_HUMAN | [view interactions] | High throughput | no | yes |
| URM1_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPHM_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBA3_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| TIPRL_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMEM9_HUMAN | [view interactions] | High throughput | no | no |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RIF1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S23IP_HUMAN | [view interactions] | High throughput | no | yes |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| PRDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RETR2_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC15_HUMAN | [view interactions] | High throughput | no | yes |
| IPO11_HUMAN | [view interactions] | High throughput | no | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRMB_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNH2A_HUMAN | [view interactions] | High throughput | no | no |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EM55_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| NEST_HUMAN | [view interactions] | High throughput | no | no |
| MSH6_HUMAN | [view interactions] | High throughput | no | yes |
| SPT20_HUMAN | [view interactions] | High throughput | no | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTA70_HUMAN | [view interactions] | High throughput | no | no |
| ANX11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FL2D_HUMAN | [view interactions] | High throughput | no | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| BAX_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NNRD_HUMAN | [view interactions] | High throughput | no | yes |
| RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG31_HUMAN | [view interactions] | High throughput | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHGH_HUMAN | [view interactions] | High throughput | no | yes |
| GLOD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| GPX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| ANRA2_HUMAN | [view interactions] | High throughput | no | no |
| FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| IPYR_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2T_HUMAN | [view interactions] | High throughput | no | no |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLRX5_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| SYJ2B_HUMAN | [view interactions] | High throughput | no | no |
| HBA_HUMAN | [view interactions] | High throughput | no | no |
| FRDA_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACOT9_HUMAN | [view interactions] | High throughput | no | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MCAT_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| HCDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| CLIC4_HUMAN | [view interactions] | High throughput | no | no |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX2_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| CE192_HUMAN | [view interactions] | High throughput | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| POC5_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN2_HUMAN | [view interactions] | High throughput | no | no |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| ECSIT_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIT5_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| RNF32_HUMAN | [view interactions] | High throughput | no | no |
| SALL1_HUMAN | [view interactions] | High throughput | no | yes |
| CAH4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GEPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCTD5_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COEA1_HUMAN | [view interactions] | High throughput | no | no |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| RTL9_HUMAN | [view interactions] | High throughput | no | no |
| DCA10_HUMAN | [view interactions] | High throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCA12_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| SOX4_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| PWP1_HUMAN | [view interactions] | High throughput | no | no |